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AYDDRGSGDPVLFIAGRGGAGRTWHLHQVPVFTRAGYRCVTFDNRGIGATENAEGFTTETMIGDTAALIE QLDLAPVRIVAVSMGSFIAQELMVARPELVHSAVLMATRGRHDRTREFFWRGEHALASSGIDLPPEFDAK VRLLESFSPKTLNDDNAVRDWIDMFTMWPQKPTPGIRTHLSISPQDNRLAAYQNVTTPALVIGFGDDVVL PPHLGREVANALPNGRFVEIPDTGHLGFIEKPEVVNTAILNFFADTL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5264 | - | - | 100% (258) | alpha/beta hydrolase fold |
| M. gilvum PYR-GCK | Mflv_1348 | - | 1e-12 | 22.45% (245) | 3-oxoadipate enol-lactonase |
| M. gilvum PYR-GCK | Mflv_2561 | - | 2e-11 | 26.39% (269) | alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0569 | bpoC | 1e-109 | 72.55% (255) | peroxidase BpoC |
| M. tuberculosis H37Rv | Rv0554 | bpoC | 1e-109 | 72.55% (255) | peroxidase BpoC |
| M. leprae Br4923 | MLBr_02269 | - | 1e-102 | 69.02% (255) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_3934c | - | 6e-88 | 58.71% (264) | alpha/beta fold hydrolase |
| M. marinum M | MMAR_0900 | bpoC | 1e-105 | 70.82% (257) | bromoperoxidase BpoC |
| M. avium 104 | MAV_4589 | - | 1e-104 | 68.75% (256) | hydrolase, alpha/beta fold family protein |
| M. smegmatis MC2 155 | MSMEG_1108 | - | 1e-113 | 75.39% (256) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_1118 | bpoC | 1e-78 | 68.53% (197) | POSSIBLE PEROXIDASE BPOC (NON-HAEM PEROXIDASE) |
| M. ulcerans Agy99 | MUL_0653 | bpoC | 1e-104 | 70.43% (257) | bromoperoxidase BpoC |
| M. vanbaalenii PYR-1 | Mvan_0974 | - | 1e-133 | 87.98% (258) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5264|M.gilvum_PYR-GCK ----------------------MAYDDRG------SGDPVLFIAGRGGAG
Mvan_0974|M.vanbaalenii_PYR-1 --------------------MNLAFDDRG------SGDPVLFIAGRGGAG
MSMEG_1108|M.smegmatis_MC2_155 MRHVVPRELRHRASSSSVSHVNLAYDERG------KGEAVLFIAGRGGAG
TH_1118|M.thermoresistible__bu --------------------------------------------------
MMAR_0900|M.marinum_M -------------------MINLAYDDKG------TGEPVLFIAGRGGAG
MUL_0653|M.ulcerans_Agy99 -------------------MINLAYDDKG------TGEPVLFIAGRGGAG
Mb0569|M.bovis_AF2122/97 -------------------MINLAYDDNG------TGDPVVFIAGRGGAG
Rv0554|M.tuberculosis_H37Rv -------------------MINLAYDDNG------TGDPVVFIAGRGGAG
MLBr_02269|M.leprae_Br4923 -------------------MINLAYEDRG------TGEPVVFIAGRGGAG
MAV_4589|M.avium_104 -------------------MINLAYDDRG------SGEPVVFIAGHGGAG
MAB_3934c|M.abscessus_ATCC_199 ------------MPLANINGIQISYDDRGPLALGASGDPVVFISGRGGAG
Mflv_5264|M.gilvum_PYR-GCK RTWHLHQVPVFTRAGYRCVTFDNRGIG-ATENAEGFTTETMIGDTAALIE
Mvan_0974|M.vanbaalenii_PYR-1 RTWHLHQVPVFTRAGYRCVTFDNRGIG-ATENASGFTTETMVGDTAALIE
MSMEG_1108|M.smegmatis_MC2_155 RTWHLNQVPEFQRAGYRVITFDNRGVG-ATENAEGFGTEQMVADTAALIE
TH_1118|M.thermoresistible__bu ----------------------------------------MVADTAALIE
MMAR_0900|M.marinum_M RTWQPHQVPAFLAAGYRCITFDNRGIG-ATENAEGFTTQTMVNDTAALIE
MUL_0653|M.ulcerans_Agy99 RTWQPHQVPAFLAAGYRCITFDNRGIG-ATENAEGFTTQTMVNDTAALIE
Mb0569|M.bovis_AF2122/97 RTWHPHQVPAFLAAGYRCITFDNRGIG-ATENAEGFTTQTMVADTAALIE
Rv0554|M.tuberculosis_H37Rv RTWHPHQVPAFLAAGYRCITFDNRGIG-ATENAEGFTTQTMVADTAALIE
MLBr_02269|M.leprae_Br4923 RTWQPHQVPAFLAAGYRVITFDNRGIG-ATENTEGFTTQTMVADTAVLIE
MAV_4589|M.avium_104 RTWHPYQVPAFLAAGYRVITFDNRGIG-ATENAQGFTTETMVADTAALIE
MAB_3934c|M.abscessus_ATCC_199 RSWHLHQVPAFRAAGYRTITFNNRGIPPTTESADGFTLQDMVDDTAALIE
*: ***.***
Mflv_5264|M.gilvum_PYR-GCK QLDLAPVRIVAVSMGSFIAQELMVARPELVHSAVLMATRGRHDRTREFFW
Mvan_0974|M.vanbaalenii_PYR-1 HLGLAPVRIVALSMGSYIAQELMVARPELVKSAVLMATRGRHDRTRDFFW
MSMEG_1108|M.smegmatis_MC2_155 KLDAAPARLVGVSMGSFIAQELMVARPELVHSAALMATRGRHDHAREFFR
TH_1118|M.thermoresistible__bu KIGAGPVRVVGVSMGSFIAQELMLARPDLVTDGVLMATRGREDHTRQFFR
MMAR_0900|M.marinum_M SLGIGPVRIVAVSMGSFIAQELMVVRPELVNSAVLMATRGRLDRARKFFH
MUL_0653|M.ulcerans_Agy99 SLGIGPVRIVAVSMGSFIAQELMVVRPELVNSAVLMATRGRLDRARKFFH
Mb0569|M.bovis_AF2122/97 TLDIAPARVVGVSMGAFIAQELMVVAPELVSSAVLMATRGRLDRARQFFN
Rv0554|M.tuberculosis_H37Rv TLDIAPARVVGVSMGAFIAQELMVVAPELVSSAVLMATRGRLDRARQFFN
MLBr_02269|M.leprae_Br4923 SLGAVPARIVGVSMGSFIAQELMVARPELVRAAVLMATRGRLDRTRQFFH
MAV_4589|M.avium_104 GLNAAPARIVGMSMGAFIAQELMLARPELVSAAVLMGTRGRMDRARQFFR
MAB_3934c|M.abscessus_ATCC_199 QLGAAPARLVGFSMGALIAQELTLTRPELVTAAVFMGTRGREDATRSFFR
:. *.*:*..***: ***** :. *:** ..:*.**** * :*.**
Mflv_5264|M.gilvum_PYR-GCK RGEHALASSGIDLPPEFDAKVRLLESFSPKTLNDDNAVRDWIDMFTMWPQ
Mvan_0974|M.vanbaalenii_PYR-1 QGERALAESGIELPIEFEAKVRLLESFSPNTLNDDNAVRDWIDMFTMWPQ
MSMEG_1108|M.smegmatis_MC2_155 KAELDLSQSGVDLPPTFDAKVRMLESFSPKTLNDDAFVRDWSEMFTMWPT
TH_1118|M.thermoresistible__bu QAERELQASGIELPPAYDAKIRLLENFSRKTLNDERTVRDWIDMFTMWPT
MMAR_0900|M.marinum_M DAEAELYDSGARMPSTYDVKDRLLENFSRKTLNDDAAVGDWLAMFSMWPI
MUL_0653|M.ulcerans_Agy99 DAEAELYDSGARMPSTYDVKDRLLENFSRKTLNDDAAVGDWLAMFSMWPI
Mb0569|M.bovis_AF2122/97 KAEAELYDSGVQLPPTYDARARLLENFSRKTLNDDVAVGDWIAMFSMWPI
Rv0554|M.tuberculosis_H37Rv KAEAELYDSGVQLPPTYDARARLLENFSRKTLNDDVAVGDWIAMFSMWPI
MLBr_02269|M.leprae_Br4923 AAEAEFHDSGIQLPSGYNAKVRLLENLSRKTLNDDVAVADWIAMFNMWPI
MAV_4589|M.avium_104 DAEAELADGGVALPASYEAKIRLLENFSRKTLNDDTAVADWIAMFSTWPV
MAB_3934c|M.abscessus_ATCC_199 KAELELSASGVEVPAAYQAAMRLLLNFSPKTLNNDAAIKDWIDMFTLWPE
.* : .* :* ::. *:* .:* :***:: : ** **. **
Mflv_5264|M.gilvum_PYR-GCK KPTPGIRTHLSISPQDNRLAAYQNVTTPALVIGFGDDVVLPPHLGREVAN
Mvan_0974|M.vanbaalenii_PYR-1 KPTPGMRTQLDIAPQGSRLSAYQSVTTPVLVIGFADDVVLPSYLGREVAN
MSMEG_1108|M.smegmatis_MC2_155 KQTPGSRTQLDVGPVTNRLPAYRSISHPVLVIGFADDVVLPAHLGREVAD
TH_1118|M.thermoresistible__bu RHTPGLRAQMDVSPQGNRLPAYRNITARVLVIGFSDDVLLPPHLGREVAD
MMAR_0900|M.marinum_M KQTPGLRCQLDAAPLTNRLPAYRNIAAPVLVIGFSDDIVTPPYLGREVAD
MUL_0653|M.ulcerans_Agy99 KQTPGLRCQLDAAPLTNRLPAYRNIAAPVLVIGFSDDIVTPPYLGREVAD
Mb0569|M.bovis_AF2122/97 KSTPGLRCQLDCAPQTNRLPAYRNIAAPVLVIGFADDVVTPPYLGREVAD
Rv0554|M.tuberculosis_H37Rv KSTPGLRCQLDCAPQTNRLPAYRNIAAPVLVIGFADDVVTPPYLGREVAD
MLBr_02269|M.leprae_Br4923 KSTPGLRCQTDVAPQNNRLPAYRSIAAPVLVIGFAEDVVTPPSLGREVAD
MAV_4589|M.avium_104 KSTPGMRAQLDVAPYTNRLSAYRSIATPVLVIGFSDDVLTPPYLGREVAD
MAB_3934c|M.abscessus_ATCC_199 PASGGIDHQRSAIPAPDRPGAYADIKVPSLVIGFTDDMTLPPYLGKEVAD
: * : . * .* ** .: ***** :*: *. **:***:
Mflv_5264|M.gilvum_PYR-GCK ALPNGRFVEIPDTGHLGFIEKPEVVNTAILNFFADTL------------
Mvan_0974|M.vanbaalenii_PYR-1 ALPNGRFLEIPGTGHLGFIEKPQVVNTAILNFFADTL------------
MSMEG_1108|M.smegmatis_MC2_155 AIPNGRYLQIPDTGHLGFIEKPQEVNAAILNFFAEHGGKKFTNLLANKL
TH_1118|M.thermoresistible__bu AIPNARYLEIPDTGHLGFIEQPQAVNEAILKFFADRL------------
MMAR_0900|M.marinum_M SLPNGRYLQIPDAGHLGFFERPEAVNTAALKFFAGTRG-----------
MUL_0653|M.ulcerans_Agy99 SLSNGRYLQIPDAGHLGFFERPEAVNTAALKFFAGTRG-----------
Mb0569|M.bovis_AF2122/97 ALPNGRYLQIPDAGHLGFFERPEAVNTAMLKFFASVKA-----------
Rv0554|M.tuberculosis_H37Rv ALPNGRYLQIPDAGHLGFFERPEAVNTAMLKFFASVKA-----------
MLBr_02269|M.leprae_Br4923 VLPNGRYLQIPDAGHLGFFERPEAVNAAALQFFAGVKGEWP--------
MAV_4589|M.avium_104 ALPNGRYVQIPDTGHLGFFERPDAVNAAMLKFFGEQH------------
MAB_3934c|M.abscessus_ATCC_199 AIPGGQYVEISDAGHLGFIERPDEVNRVILEFFASTAQTV---------
:...::::*..:*****:*:*: ** . *:**.