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MATPEEPLNSSVDTAPKPSEPARTALLGAMFLMATSAVGPGFITQTTEFTVELGAAFAFAILASIVIDFA VQMNVWRVIGVAGIRAHELGNKVLPGVGYALAVLVVVGGLVFNIGNTSGAGLGTDAMFGLDPRIGGAVSA LIAIAIFLSKRAGIALDRIVVVLGIAMIAMTAYTAIVSRPPLGEALRNAVLPEQISFLAITTIVGGTVGG YITYAGAHRLLDTGITGPENVSRITLGSTYAIIVTGIMRALLFLAILGVTAGGVSLASDNPTASAFEYAL GAAGGIIFGVILWAASITSVIGAAYTSVSFLTKSTTPRRRQNILTVGFIALSAALFVILGAAPVTLLVFA GAFNGLILPIGFTVVLWVAWVRRDLLGGYRYPMWLKIVGLAVWLLTLYLGWNSLSGLSSLWS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5193 | - | - | 100% (412) | hypothetical protein Mflv_5193 |
| M. gilvum PYR-GCK | Mflv_1822 | - | 8e-09 | 21.28% (343) | Mn2+/Fe2+ transporter |
| M. gilvum PYR-GCK | Mflv_4722 | - | 3e-05 | 23.94% (355) | amino acid permease-associated region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0948c | mntH | 1e-09 | 23.51% (404) | putative manganese transport protein MntH |
| M. tuberculosis H37Rv | Rv0924c | mntH | 1e-09 | 23.51% (404) | manganese transport protein MntH |
| M. leprae Br4923 | MLBr_02098 | mntH | 7e-08 | 22.19% (392) | manganese transport protein MntH |
| M. abscessus ATCC 19977 | MAB_1031c | - | 2e-08 | 20.90% (378) | manganese transport protein MntH |
| M. marinum M | MMAR_4584 | mntH | 9e-10 | 23.63% (347) | divalent cation-transport integral membrane protein MntH |
| M. avium 104 | MAV_1044 | - | 4e-08 | 22.39% (402) | manganese transport protein MntH |
| M. smegmatis MC2 155 | MSMEG_5589 | - | 4e-08 | 20.82% (341) | manganese transport protein MntH |
| M. thermoresistible (build 8) | TH_3825 | - | 5e-07 | 22.91% (419) | PUTATIVE putative Na+/solute symporter |
| M. ulcerans Agy99 | MUL_4445 | mntH | 1e-09 | 23.63% (347) | manganese transport protein MntH |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0948c|M.bovis_AF2122/97 MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5193|M.gilvum_PYR-GCK --------------------------------------------------
TH_3825|M.thermoresistible__bu --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 GVQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLCGP
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5193|M.gilvum_PYR-GCK --------------------------------------------------
TH_3825|M.thermoresistible__bu --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 IWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCLITGNEDGVKH
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5193|M.gilvum_PYR-GCK --------------------------------------------------
TH_3825|M.thermoresistible__bu --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 CAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDFTNRN
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5193|M.gilvum_PYR-GCK --------------------------------------------------
TH_3825|M.thermoresistible__bu --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 TTFMTFNLMHIAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTTDSQRRS
Rv0924c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4584|M.marinum_M --------------------------------------------------
MUL_4445|M.ulcerans_Agy99 --------------------------------------------------
MAV_1044|M.avium_104 --------------------------------------------------
MLBr_02098|M.leprae_Br4923 --------------------------------------------------
MAB_1031c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5589|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_5193|M.gilvum_PYR-GCK --------------------------------------------------
TH_3825|M.thermoresistible__bu --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 RVARWLVAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
Rv0924c|M.tuberculosis_H37Rv ------MAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAFVAAI
MMAR_4584|M.marinum_M --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
MUL_4445|M.ulcerans_Agy99 --------------------------MAQDTQTSFKTSWYLLGPAFVAAI
MAV_1044|M.avium_104 --------------------------MAQRTQGSLKGNWYLLGPAFVAAI
MLBr_02098|M.leprae_Br4923 --------MFVNLTCLSEGNGSRGKALAESTQAELKTSWYLLGPAFVAAI
MAB_1031c|M.abscessus_ATCC_199 -------------------------MLERQKQARPLRGLSLLGPAFVAAI
MSMEG_5589|M.smegmatis_MC2_155 -------------------------MLEDTK-VRARPSWLLLGPAFVAAI
Mflv_5193|M.gilvum_PYR-GCK ---------------MATPEEPLNSSVDTAPKPSEPARTALLGAMFLMAT
TH_3825|M.thermoresistible__bu ----MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVAGRALPAVLVAAV
* . :: *
Mb0948c|M.bovis_AF2122/97 AYVDPGN---VAANVSSGAQFGYLLLWVIVAANVMAALVQ--YLSAKLGL
Rv0924c|M.tuberculosis_H37Rv AYVDPGN---VAANVSSGAQFGYLLLWVIVAANVMAALVQ--YLSAKLGL
MMAR_4584|M.marinum_M AYVDPGN---VAANVSSGAQFGYLLLWVIVVANVMAGLVQ--YLSAKLGL
MUL_4445|M.ulcerans_Agy99 AYVDPGN---VAANVSSGAQFGYLLLWVIVVANVMAGLVQ--YLSAKLGL
MAV_1044|M.avium_104 AYVDPGN---VAANVSAGSQYGYLLLWVIVAANVLAGLVQ--YLSAKLGL
MLBr_02098|M.leprae_Br4923 AYVDPGN---VAANVSSGAQFGYLQLWVVVVANVLAGLVQ--YLSAKLGL
MAB_1031c|M.abscessus_ATCC_199 AYVDPGN---VASNVSAGAKYGFLLVWVIVTANVMAGLVQ--YLSAKLGL
MSMEG_5589|M.smegmatis_MC2_155 AYVDPGN---VAANVSAGAQYGFLLVWVIVVANVMAGLVQ--YLSAKLGL
Mflv_5193|M.gilvum_PYR-GCK SAVGPGF---ITQTTEFTVELGAAFAFAILASIVIDFAVQ--MNVWRVIG
TH_3825|M.thermoresistible__bu LIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLLMGLFFARRLRA
. * ... * .: . .: : ::
Mb0948c|M.bovis_AF2122/97 VTGRSLPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFN
Rv0924c|M.tuberculosis_H37Rv VTGRSLPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFN
MMAR_4584|M.marinum_M VTGHSLPEQIGKRMGRPARLTYWVQAEIVAIATDVAEVVGGAIALRILFG
MUL_4445|M.ulcerans_Agy99 VTGHSLPEQIGKRMGRPARLTYWVQAEIVAIATDMAEVVGGAIALRILFG
MAV_1044|M.avium_104 VTGRSLPATIGKRMSRPARLVYWVQAELVAIATDAAEVVGGAIALHILFG
MLBr_02098|M.leprae_Br4923 VTGQSLPQAISKQMSHPFRLGFWLQAELVAMATDVAEIVGGAIAFHILFR
MAB_1031c|M.abscessus_ATCC_199 VTGQSLPEAIGDRMARPTRLTFWLQAELVAMATDLAEVVGGAIALHLLFG
MSMEG_5589|M.smegmatis_MC2_155 VTGRSLPEAVADHTRTPTRVAFWLQAELVAMATDLAEVVGGAIALYLLFD
Mflv_5193|M.gilvum_PYR-GCK VAG-IRAHELGNKVLPGVGYALAVLVVVGGLVFNIGNTSGAGLGTDAMFG
TH_3825|M.thermoresistible__bu AQVVTLPEYFGNRFGRGVEVASSALTVGSFAILLAGNLVAIGFLLERFLG
. . ...: . .: . .: ::
Mb0948c|M.bovis_AF2122/97 LPLPIGGIITGVVSLLLLTIQDRRGQRL--FERVITALLLVIAIGFTASF
Rv0924c|M.tuberculosis_H37Rv LPLPIGGIITGVVSLLLLTIQDRRGQRL--FERVITALLLVIAIGFTASF
MMAR_4584|M.marinum_M LPLPIGGIITGVISLLLLLIQDRRGQLL--FERVITGLLLIIAVGFTASF
MUL_4445|M.ulcerans_Agy99 LPLPIGGIITGVISLLLLLIQDRRGQLL--FERVITGLLLIIAVGFTASF
MAV_1044|M.avium_104 LPLLAGGLITGVVALLLLGIQDRRGQIL--FERVITGLLLVIAIGFAASF
MLBr_02098|M.leprae_Br4923 VSLLLGGVITGTVSLLLLMVKDRRGQLL--FERVITGLLFVIVVGFTSSF
MAB_1031c|M.abscessus_ATCC_199 LPLLLGGVITGIVSMALLTVQDRRGQRS--FEYVISALLAIIAIGFLASV
MSMEG_5589|M.smegmatis_MC2_155 LPLLVGGLITGVVSLLLLAVQNRRGQRV--FERVITGLLMVIAIGFLTSL
Mflv_5193|M.gilvum_PYR-GCK LDPRIGGAVSALIAIAIFLS-KRAGIAL--DRIVVVLGIAMIAMTAYTAI
TH_3825|M.thermoresistible__bu VSYTIGILVTVPLALLYTITGGMFASVYTGVAQVVVNIVGVFALVVWVAA
: * :: ::: . *: : ::.: :
Mb0948c|M.bovis_AF2122/97 FVVTPPPNAVLGGLAPRFQGTES----------VLLAAAIMGATVMPHAV
Rv0924c|M.tuberculosis_H37Rv FVVTPPPNAVLGGLAPRFQGTES----------VLLAAAIMGATVMPHAV
MMAR_4584|M.marinum_M FVATPPPDAMFTGLVPHFQGTES----------VLLAAAILGATVMPHAV
MUL_4445|M.ulcerans_Agy99 FVATPPPDAMFTGLVPHFQGTES----------VLLAAAILGATVMPHAV
MAV_1044|M.avium_104 FVKTAPPEAVLSGLLPRFRGTES----------VLLAAAILGATVMPHAV
MLBr_02098|M.leprae_Br4923 FVATPSPEDMVNGLLPRFQGTES----------VLLAAAIIGATVMPHAV
MAB_1031c|M.abscessus_ATCC_199 VVEPPPLPEAAAGLIPHFQGTES----------LLLATAMLGATVMPHAV
MSMEG_5589|M.smegmatis_MC2_155 FVKTPPAAAVADGLIPRFDGAES----------ILLATAMLGATVMPHAV
Mflv_5193|M.gilvum_PYR-GCK VSRPPLGEALRNAVLP---EQIS----------FLAITTIVGGTVGGYIT
TH_3825|M.thermoresistible__bu THGFTAPDGMGAGALSQLTSSESGAVINWATIIALGLGNLVAIDLMQRVF
. . . * * ::. :
Mb0948c|M.bovis_AF2122/97 YLHSGLARDRHGHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAA
Rv0924c|M.tuberculosis_H37Rv YLHSGLARDRHGHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAA
MMAR_4584|M.marinum_M YLHSGLARDRHGHPEPGPYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAA
MUL_4445|M.ulcerans_Agy99 YLHSGLARDRHGHPEPGPYRRRLLRVTRWDVGLAMIVAGGVNAAMLLVAA
MAV_1044|M.avium_104 YMHSGLVLDRHGHPDEGPHRRLLLRVTRWDVVLAMAVAGTVNAAMLLIAA
MLBr_02098|M.leprae_Br4923 YLHSGLALDRHGHPHAGRSRRRLLRVTRLDVILAMTIAGIVNTAMLLVAA
MAB_1031c|M.abscessus_ATCC_199 YLHSGLTRDRHGRPAEGEPRRRLLRITRWDVCLAMVFAGAVNMAMLLAAA
MSMEG_5589|M.smegmatis_MC2_155 YLHSGLARDRHG-HAEGPRLRMLLRVTRFDVGLAMLVAGAVNMAMLLVAA
Mflv_5193|M.gilvum_PYR-GCK YAG------AHRLLDTGITGPENVSRITLGSTYAIIVTGIMRALLFLAIL
TH_3825|M.thermoresistible__bu SARDPGAAQRACFAAAGGILLLCLPLSFVALAAVGIVGDSAGDGPILYAL
* : . . . :*
Mb0948c|M.bovis_AF2122/97 LNMRGRGDTASIEGAYHAVHDTLGATIAVLFAVGLLASGLASSSVGAYAG
Rv0924c|M.tuberculosis_H37Rv LNMRGRGDTASIEGAYHAVHDTLGATIAVLFAVGLLASGLASSSVGAYAG
MMAR_4584|M.marinum_M LNLQGREDTASIEGAYAAVHDTLGATIAVLFAIGLLASGLASTSVGAYAG
MUL_4445|M.ulcerans_Agy99 LNLQGREDTASIEGAYAAVHDTLGATIAVLFAIGLLASGLASTSVGAYAG
MAV_1044|M.avium_104 TNLQHRDVSASIEGAYAAIHNTLGATIAVMFAVGLLASGLASSSVGAYAG
MLBr_02098|M.leprae_Br4923 INLQHHQVTAYIEGTYTAIQDTLGATIAMLFAIGLLASSLASASVGAYAG
MAB_1031c|M.abscessus_ATCC_199 TNLRGRDGVDTIEGAHAAVRDSLGPTVALLFAIGLLASGLASSSVGAYAG
MSMEG_5589|M.smegmatis_MC2_155 TNLQGRGDTDSIEGAHAAVSDALGPTVALLFAIGLLASGLASTSVGAYAG
Mflv_5193|M.gilvum_PYR-GCK GVTAGGVSLASDNPTASAFEYALGAAGGIIFGVILWAASITSVIGAAYTS
TH_3825|M.thermoresistible__bu LGEYAPAWLAIIVISGLLAATLTTVSGILLSTASVLVRNVLRIDTGVLAP
: : :: : . .: .. :
Mb0948c|M.bovis_AF2122/97 AMIMQG--LLHWSVPMLVRRLITLGPALAILTLGFDPTRTLVLSQVVLSF
Rv0924c|M.tuberculosis_H37Rv AMIMQG--LLHWSVPMLVRRLITLGPALAILTLGFDPTRTLVLSQVVLSF
MMAR_4584|M.marinum_M AMIMQG--LLHWSVPMAVRRLVTLCPAVAILALGLDPTRTLVLSQVVLSF
MUL_4445|M.ulcerans_Agy99 AMIMQG--LLHWSVPMAVRRLVTLCPAVAILALGLDPTRTLVLSQVVLSF
MAV_1044|M.avium_104 AMIMQG--LLHRSIPMVVRRLITLCPALLILAVGYDTTRALVLSQVVLSF
MLBr_02098|M.leprae_Br4923 ALIMQG--LLQRSIPMLIRRLITLCPAIAILALGFDPTRALVLSQIVLSF
MAB_1031c|M.abscessus_ATCC_199 AMIMQG--LLRRSIPIVARRLITLLPALAILAAGIDPTRALVISQVVLSF
MSMEG_5589|M.smegmatis_MC2_155 AMIMQG--LLKKSYPLLLRRLVTLVPALLVLAIGVDPSRALVLSQVVLSF
Mflv_5193|M.gilvum_PYR-GCK VSFLTKSTTPRRRQNILTVGFIALS-AALFVILGAAPVTLLVFAGAFNGL
TH_3825|M.thermoresistible__bu PAAMTP--RMLRATRWATLPMAALAAVVALRVPQTGILLTLAFDLLLASL
: : :* . . *.: . .:
Mb0948c|M.bovis_AF2122/97 GIPFAVLPLVKLTGSP-AVMGGDTNHRATTWVGWVVAVMVSLLNVMLIYL
Rv0924c|M.tuberculosis_H37Rv GIPFAVLPLVKLTGSP-AVMGGDTNHRATTWVGWVVAVMVSLLNVMLIYL
MMAR_4584|M.marinum_M GIPFAVLPLVRLTSNP-EVMGSDTNHRLTTWIGWGVAVLISVLNVALIYL
MUL_4445|M.ulcerans_Agy99 GIPFAVLPLVRLTSNP-EVMGSDTNHRLTTWIGWGVAVLISVLNVALIYL
MAV_1044|M.avium_104 GIPFAVLPLIKLTSDR-ELMGSDANHRITTILGWGVGILISLLNMVLIWL
MLBr_02098|M.leprae_Br4923 GIPFAVLPLVKLTNNR-GLMGNDTNHPATTVLGWAVAILVSLLNVVLIYL
MAB_1031c|M.abscessus_ATCC_199 GIPFALIPLIRLTGDR-RLMGSDANHRVTTLLGWIIAALISALNVVLIFL
MSMEG_5589|M.smegmatis_MC2_155 GIPFALIPLVRLTSDK-ALMGGDANHRVTTAFGWGVAGLISVLNVVLIYL
Mflv_5193|M.gilvum_PYR-GCK ILPIGFTVVLWVAWVRRDLLGGYRYPMWLKIVGLAVWLLTLYLGWNSLSG
TH_3825|M.thermoresistible__bu VVPFILG-LYWSRGGAAAAAAAVVVGIGVRLTYFVLAPTIYGVDNTLLYL
:*: . : . : :. :
Mb0948c|M.bovis_AF2122/97 TVTG-------------------------------
Rv0924c|M.tuberculosis_H37Rv TVTG-------------------------------
MMAR_4584|M.marinum_M TLTG-------------------------------
MUL_4445|M.ulcerans_Agy99 TLTG-------------------------------
MAV_1044|M.avium_104 TVTG-------------------------------
MLBr_02098|M.leprae_Br4923 TVTS-------------------------------
MAB_1031c|M.abscessus_ATCC_199 TLAN-------------------------------
MSMEG_5589|M.smegmatis_MC2_155 TVNG-------------------------------
Mflv_5193|M.gilvum_PYR-GCK LSSLWS-----------------------------
TH_3825|M.thermoresistible__bu PNDWVSAXXRGGGPSGVRDTPSDTPREMHPRNALA