For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_5121 (-)

annotation: (3R)-hydroxyacyl-ACP dehydratase subunit HadA
coordinates: 5443139 - 5443618
length: 159

SFLDGFVGTHFRYPDHYVVGREKIREYAVAVKNSDPAFFDEDAAAELGHDALLAPLTFISVFGYQAQWAM
FAANNIGISDAKIVQVDQSLRFVRPIKAGDELYCDVWIDSIRKAHGTDIIVTKNIVSNGNGDVVQESYTT
LAGRSEEDGESGFSDGIA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_5121--100% (159)(3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. gilvum PYR-GCKMflv_0070-2e-3042.07% (145) MaoC-like dehydratase
M. gilvum PYR-GCKMflv_5119-1e-2945.64% (149) (3R)-hydroxyacyl-ACP dehydratase subunit HadC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0654-5e-5769.74% (152) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. tuberculosis H37RvRv0635-5e-5769.74% (152) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. leprae Br4923MLBr_01910-7e-5966.04% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. abscessus ATCC 19977MAB_3898c-4e-5564.71% (153) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. marinum MMMAR_0968-1e-5868.55% (159) hypothetical protein MMAR_0968
M. avium 104MAV_4527-1e-5562.89% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. smegmatis MC2 155MSMEG_1340-1e-5866.67% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. thermoresistible (build 8)TH_1868-1e-5970.44% (159) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0720-4e-5867.92% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. vanbaalenii PYR-1Mvan_1230-2e-7484.28% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5121|M.gilvum_PYR-GCK          MSFLDGFVGTHFRYPDHYVVGREKIREYAVAVKNSDPAFFDEDAAAELGH
Mvan_1230|M.vanbaalenii_PYR-1       MSLLDGLVGSHFRYPDHYVVGREKIREYAVAVKNDDAAFFEESVADELGY
Mb0654|M.bovis_AF2122/97            MALSADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGY
Rv0635|M.tuberculosis_H37Rv         MALSADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGY
MLBr_01910|M.leprae_Br4923          MGLTTNIVGMHYRYPDHYEVEREKIREYAVAVQNEDTSYFEEDAAAELGY
MAV_4527|M.avium_104                MPLTTNLVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEKAASELGY
MMAR_0968|M.marinum_M               MALTEDIVGMHFRYPDHYVVEREKIREYAVAVLNDDASFFEEGAAADLGH
MUL_0720|M.ulcerans_Agy99           MALTEDIVGMHFRYPDHYVVEREKIREYAVAVLNDDASFFEEGAAADLGH
MSMEG_1340|M.smegmatis_MC2_155      MALSSKIVGMHYRYPDFYEVGREKIREHALAIKNDETYFYDEDAAAELGH
TH_1868|M.thermoresistible__bu      VALSQDIVGKRFTYPDHYIVGREKIREYAVAVKNDDEVFFDENAAKELGH
MAB_3898c|M.abscessus_ATCC_199      MALSQDLVGTHYRYPDHYVVGREKIREHAEAVKCHHPAHHDEAGAAELGH
                                    : :   :** :: ***.* * ******:* *:   .  ..:*  * :**:

Mflv_5121|M.gilvum_PYR-GCK          DALLAPLTFISVFGYQAQWAMFAANNIGISDAKIVQVDQSLRFVRPIKAG
Mvan_1230|M.vanbaalenii_PYR-1       DSLLAPLTFISVFGYQAQRAMFEANNIALADAKIVQVDQVLKFVAPIKAG
Mb0654|M.bovis_AF2122/97            KGLLAPLTFICVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAG
Rv0635|M.tuberculosis_H37Rv         KGLLAPLTFICVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAG
MLBr_01910|M.leprae_Br4923          KGLLAPLTFICLFGYKAQSAFFKHANIAVTDQQIVQIDQVLKFVKPIVAG
MAV_4527|M.avium_104                KGLLAPLTFVCVFGYMAQSSFFKHANIAVKDAQIVQVDQVLKFYAPLVAG
MMAR_0968|M.marinum_M               KGLLAPLTFISVFGYKAQSAFFKHANIGVSDQQIVQVDQVLKFSKPIVAG
MUL_0720|M.ulcerans_Agy99           KGLLAPLTFISVFGYKAQSAFFKHANIGVSDQQIVQVDQVLKFSKPIVAG
MSMEG_1340|M.smegmatis_MC2_155      DALPAPLTFICIFGYQAQSAFFDHADIGVREAKIVQVDQELKFFKPIKAG
TH_1868|M.thermoresistible__bu      DALPAPLTFISVFGYYAQRAFFDHANIGITDAKIVQVDQEFRFLKPIRAG
MAB_3898c|M.abscessus_ATCC_199      SALVAPPTFLAVFGYTAQSAFFEDANIGIKDEKIVQVDQAFKYIRPVRSG
                                    ..* ** **:.:*** ** ::*   :*.  : :***:** :::  *: :*

Mflv_5121|M.gilvum_PYR-GCK          DELYCDVWIDSIRKAHGTDIIVTKNIVSNGNGDVVQESYTTLAGRSEEDG
Mvan_1230|M.vanbaalenii_PYR-1       DTLYCDVWVDSIRKAHGTDIIVTKNIVSRENGEVVQESYTTLAGRSEEDG
Mb0654|M.bovis_AF2122/97            DKLYCDVYVDSVREAHGTQIIVTKNIVTNEEGDLVQETYTTLAGRAGEDG
Rv0635|M.tuberculosis_H37Rv         DKLYCDVYVDSVREAHGTQIIVTKNIVTNEEGDLVQETYTTLAGRAGEDG
MLBr_01910|M.leprae_Br4923          DKLYCDVYVDSMREAHGTQIIVTKNVVTNEVGDIVQETYTTLAGRVGEGG
MAV_4527|M.avium_104                DKLYCDVYVDSVRVSHGTQIIVTKNVITNEAGDVVQETYTTLAGRAGEDG
MMAR_0968|M.marinum_M               DILHCDVHVDSVREAHGTQIIVTRNIVTNEAGEIVQETLTTLAGRVGEDG
MUL_0720|M.ulcerans_Agy99           DILHCDVHVDSVREAHDTQIIVTRNIVTNEAGEIVQETLTTLAGRVGEDG
MSMEG_1340|M.smegmatis_MC2_155      DRLYCDVYVHAVRRAHGTDIIVTKNIITNDAGEIVQEAYTTLAGRAG-DG
TH_1868|M.thermoresistible__bu      DKLYCEVSVHSVRQSFGTDIIVTKNIVTNEAGEVVQEAYTTLAGRSDETG
MAB_3898c|M.abscessus_ATCC_199      DTLYCDVYVDSIRRSFGTDIIVIKNIITNDKGEFVTESYTTLAGRAEDDG
                                    * *:*:* :.::* :..*:*** :*:::.  *:.* *: ******    *

Mflv_5121|M.gilvum_PYR-GCK          ESGFSDGIA
Mvan_1230|M.vanbaalenii_PYR-1       ESGFSDGTA
Mb0654|M.bovis_AF2122/97            E-GFSDGAA
Rv0635|M.tuberculosis_H37Rv         E-GFSDGAA
MLBr_01910|M.leprae_Br4923          EEGFSDGAA
MAV_4527|M.avium_104                EEGFTDATA
MMAR_0968|M.marinum_M               EEGFSDGTA
MUL_0720|M.ulcerans_Agy99           EEGFSDGTA
MSMEG_1340|M.smegmatis_MC2_155      EEGFSDGSA
TH_1868|M.thermoresistible__bu      E-GFADGSA
MAB_3898c|M.abscessus_ATCC_199      EEGGFN---
                                    * *  :