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M. leprae Br4923 MLBr_01910 (-)

annotation: (3R)-hydroxyacyl-ACP dehydratase subunit HadA
coordinates: 2293988 - 2294467
length: 159

GLTTNIVGMHYRYPDHYEVEREKIREYAVAVQNEDTSYFEEDAAAELGYKGLLAPLTFICLFGYKAQSAF
FKHANIAVTDQQIVQIDQVLKFVKPIVAGDKLYCDVYVDSMREAHGTQIIVTKNVVTNEVGDIVQETYTT
LAGRVGEGGEEGFSDGAA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. leprae Br4923 MLBr_01910 - - 100% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. leprae Br4923 MLBr_01908 - 5e-35 44.08% (152) (3R)-hydroxyacyl-ACP dehydratase subunit HadC
M. leprae Br4923 MLBr_02425 - 1e-28 40.71% (140) hypothetical protein MLBr_02425

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0654 - 2e-76 85.53% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. gilvum PYR-GCK Mflv_5121 - 2e-58 66.04% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. tuberculosis H37Rv Rv0635 - 2e-76 85.53% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. abscessus ATCC 19977 MAB_3898c - 4e-50 57.52% (153) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. marinum M MMAR_0968 - 1e-72 81.76% (159) hypothetical protein MMAR_0968
M. avium 104 MAV_4527 - 1e-75 82.39% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. smegmatis MC2 155 MSMEG_1340 - 9e-63 69.18% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. thermoresistible (build 8) TH_1868 - 2e-55 64.78% (159) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99 MUL_0720 - 5e-72 81.13% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. vanbaalenii PYR-1 Mvan_1230 - 2e-59 67.92% (159) (3R)-hydroxyacyl-ACP dehydratase subunit HadA

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5121|M.gilvum_PYR-GCK          MSFLDGFVGTHFRYPDHYVVGREKIREYAVAVKNSDPAFFDEDAAAELGH
Mvan_1230|M.vanbaalenii_PYR-1       MSLLDGLVGSHFRYPDHYVVGREKIREYAVAVKNDDAAFFEESVADELGY
Mb0654|M.bovis_AF2122/97            MALSADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGY
Rv0635|M.tuberculosis_H37Rv         MALSADIVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEDGAAELGY
MLBr_01910|M.leprae_Br4923          MGLTTNIVGMHYRYPDHYEVEREKIREYAVAVQNEDTSYFEEDAAAELGY
MAV_4527|M.avium_104                MPLTTNLVGMHYRYPDHYEVEREKIREYAVAVQNDDAWYFEEKAASELGY
MMAR_0968|M.marinum_M               MALTEDIVGMHFRYPDHYVVEREKIREYAVAVLNDDASFFEEGAAADLGH
MUL_0720|M.ulcerans_Agy99           MALTEDIVGMHFRYPDHYVVEREKIREYAVAVLNDDASFFEEGAAADLGH
MSMEG_1340|M.smegmatis_MC2_155      MALSSKIVGMHYRYPDFYEVGREKIREHALAIKNDETYFYDEDAAAELGH
TH_1868|M.thermoresistible__bu      VALSQDIVGKRFTYPDHYIVGREKIREYAVAVKNDDEVFFDENAAKELGH
MAB_3898c|M.abscessus_ATCC_199      MALSQDLVGTHYRYPDHYVVGREKIREHAEAVKCHHPAHHDEAGAAELGH
                                    : :   :** :: ***.* * ******:* *:   .  ..:*  * :**:

Mflv_5121|M.gilvum_PYR-GCK          DALLAPLTFISVFGYQAQWAMFAANNIGISDAKIVQVDQSLRFVRPIKAG
Mvan_1230|M.vanbaalenii_PYR-1       DSLLAPLTFISVFGYQAQRAMFEANNIALADAKIVQVDQVLKFVAPIKAG
Mb0654|M.bovis_AF2122/97            KGLLAPLTFICVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAG
Rv0635|M.tuberculosis_H37Rv         KGLLAPLTFICVFGYKAQAAFFKHANIATAEAQIVQVDQVLKFEKPIVAG
MLBr_01910|M.leprae_Br4923          KGLLAPLTFICLFGYKAQSAFFKHANIAVTDQQIVQIDQVLKFVKPIVAG
MAV_4527|M.avium_104                KGLLAPLTFVCVFGYMAQSSFFKHANIAVKDAQIVQVDQVLKFYAPLVAG
MMAR_0968|M.marinum_M               KGLLAPLTFISVFGYKAQSAFFKHANIGVSDQQIVQVDQVLKFSKPIVAG
MUL_0720|M.ulcerans_Agy99           KGLLAPLTFISVFGYKAQSAFFKHANIGVSDQQIVQVDQVLKFSKPIVAG
MSMEG_1340|M.smegmatis_MC2_155      DALPAPLTFICIFGYQAQSAFFDHADIGVREAKIVQVDQELKFFKPIKAG
TH_1868|M.thermoresistible__bu      DALPAPLTFISVFGYYAQRAFFDHANIGITDAKIVQVDQEFRFLKPIRAG
MAB_3898c|M.abscessus_ATCC_199      SALVAPPTFLAVFGYTAQSAFFEDANIGIKDEKIVQVDQAFKYIRPVRSG
                                    ..* ** **:.:*** ** ::*   :*.  : :***:** :::  *: :*

Mflv_5121|M.gilvum_PYR-GCK          DELYCDVWIDSIRKAHGTDIIVTKNIVSNGNGDVVQESYTTLAGRSEEDG
Mvan_1230|M.vanbaalenii_PYR-1       DTLYCDVWVDSIRKAHGTDIIVTKNIVSRENGEVVQESYTTLAGRSEEDG
Mb0654|M.bovis_AF2122/97            DKLYCDVYVDSVREAHGTQIIVTKNIVTNEEGDLVQETYTTLAGRAGEDG
Rv0635|M.tuberculosis_H37Rv         DKLYCDVYVDSVREAHGTQIIVTKNIVTNEEGDLVQETYTTLAGRAGEDG
MLBr_01910|M.leprae_Br4923          DKLYCDVYVDSMREAHGTQIIVTKNVVTNEVGDIVQETYTTLAGRVGEGG
MAV_4527|M.avium_104                DKLYCDVYVDSVRVSHGTQIIVTKNVITNEAGDVVQETYTTLAGRAGEDG
MMAR_0968|M.marinum_M               DILHCDVHVDSVREAHGTQIIVTRNIVTNEAGEIVQETLTTLAGRVGEDG
MUL_0720|M.ulcerans_Agy99           DILHCDVHVDSVREAHDTQIIVTRNIVTNEAGEIVQETLTTLAGRVGEDG
MSMEG_1340|M.smegmatis_MC2_155      DRLYCDVYVHAVRRAHGTDIIVTKNIITNDAGEIVQEAYTTLAGRAG-DG
TH_1868|M.thermoresistible__bu      DKLYCEVSVHSVRQSFGTDIIVTKNIVTNEAGEVVQEAYTTLAGRSDETG
MAB_3898c|M.abscessus_ATCC_199      DTLYCDVYVDSIRRSFGTDIIVIKNIITNDKGEFVTESYTTLAGRAEDDG
                                    * *:*:* :.::* :..*:*** :*:::.  *:.* *: ******    *

Mflv_5121|M.gilvum_PYR-GCK          ESGFSDGIA
Mvan_1230|M.vanbaalenii_PYR-1       ESGFSDGTA
Mb0654|M.bovis_AF2122/97            E-GFSDGAA
Rv0635|M.tuberculosis_H37Rv         E-GFSDGAA
MLBr_01910|M.leprae_Br4923          EEGFSDGAA
MAV_4527|M.avium_104                EEGFTDATA
MMAR_0968|M.marinum_M               EEGFSDGTA
MUL_0720|M.ulcerans_Agy99           EEGFSDGTA
MSMEG_1340|M.smegmatis_MC2_155      EEGFSDGSA
TH_1868|M.thermoresistible__bu      E-GFADGSA
MAB_3898c|M.abscessus_ATCC_199      EEGGFN---
                                    * *  :

species	id	gene	e-value	identity (len)	annotation
M. leprae Br4923	MLBr_01910	-	-	100% (159)	(3R)-hydroxyacyl-ACP dehydratase subunit HadA
M. leprae Br4923	MLBr_01908	-	5e-35	44.08% (152)	(3R)-hydroxyacyl-ACP dehydratase subunit HadC
M. leprae Br4923	MLBr_02425	-	1e-28	40.71% (140)	hypothetical protein MLBr_02425