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ALKTDIRGMVWEYPDVFVVAREQIRQYANAVKAKDPASHDEAAAAELGHGGVVAGPTFMSIFAVMIQNHF FQNVDIGLETMQIVQVDQKFLFHRPIKDGDRLRGVMTILTVDERFGADIVTTRNVLTDDAGEVVMESFTT LMGHEGDNSISAGWDPETGQVVRKPVKHDEDVAEDVPEDVTAAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5119 | - | - | 100% (185) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. gilvum PYR-GCK | Mflv_5121 | - | 1e-29 | 45.64% (149) | (3R)-hydroxyacyl-ACP dehydratase subunit HadA |
| M. gilvum PYR-GCK | Mflv_0070 | - | 4e-26 | 36.59% (164) | MaoC-like dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0656 | - | 4e-54 | 59.76% (164) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. tuberculosis H37Rv | Rv0637 | - | 4e-54 | 59.76% (164) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. leprae Br4923 | MLBr_01908 | - | 6e-54 | 59.76% (164) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. abscessus ATCC 19977 | MAB_3896c | - | 1e-43 | 53.38% (148) | hypothetical protein MAB_3896c |
| M. marinum M | MMAR_0970 | - | 1e-55 | 60.37% (164) | hypothetical protein MMAR_0970 |
| M. avium 104 | MAV_4525 | - | 5e-53 | 60.00% (165) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. smegmatis MC2 155 | MSMEG_1342 | - | 3e-67 | 68.86% (167) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. thermoresistible (build 8) | TH_1866 | - | 1e-75 | 78.49% (172) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0722 | - | 7e-56 | 60.37% (164) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
| M. vanbaalenii PYR-1 | Mvan_1232 | - | 4e-90 | 91.18% (170) | (3R)-hydroxyacyl-ACP dehydratase subunit HadC |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5119|M.gilvum_PYR-GCK MALKTDIRGMVWEYPDVFVVAREQIRQYANAVKAKDPASHDEAAAAELGH
Mvan_1232|M.vanbaalenii_PYR-1 MALKTDIRGMVWEYPDVFVVAREQIRQYANSVKAKDPATHDEAAAAELGH
TH_1866|M.thermoresistible__bu MALKTDIRGMVWPYPDKFVVGREQIRQYAAAVKAFDPATHDEAAAAELGH
Mb0656|M.bovis_AF2122/97 MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGY
Rv0637|M.tuberculosis_H37Rv MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGY
MLBr_01908|M.leprae_Br4923 MALKTDIRGMVWRYSDYFIVGREQCREFARAIKCDHPAYFSEDAAAELGY
MAV_4525|M.avium_104 MALKTDIRGMIWRYPDYFVVGREQLRQFALSVKNRHPAHFSEDAAAELGH
MMAR_0970|M.marinum_M MALKTDIRGMSWKYPDCFVVGREQVRGFARSVQCDDAACYEEDAAAKLGY
MUL_0722|M.ulcerans_Agy99 MALKTDIRGMSWKYPDCFVVGREQVRGFARSVQCDDAACYEEDAAAKLGY
MSMEG_1342|M.smegmatis_MC2_155 MALKTDIKGMVWKYPDPFLIGREQIRQYAKAVKAMDPASHDEAAAAELGH
MAB_3896c|M.abscessus_ATCC_199 MALSLDVVGMTHKYSQTYVVGREKIREFAKSIKCESPASHDVAAATALGH
***. *: ** *.: :::.**: * :* ::: .* .. **: **:
Mflv_5119|M.gilvum_PYR-GCK GGVVAGPTFMSIFAVMIQNHFFQNVDIGLETMQIVQVDQKFLFHRPIKDG
Mvan_1232|M.vanbaalenii_PYR-1 SGIIAPPTFMSIFAVMIQNHFFQHVDVGLETLQIVQVDQRFLFHRPIKDG
TH_1866|M.thermoresistible__bu DNIIAPLTFTAIFAVMIQRHFFQNVDVGFETMQIVQVDQKFKYYRPLKPG
Mb0656|M.bovis_AF2122/97 DALVAPLTFVTILAKYVQLDFFRHVDVGMETMQIVQVDQRFVFHKPVLAG
Rv0637|M.tuberculosis_H37Rv DALVAPLTFVTILAKYVQLDFFRHVDVGMETMQIVQVDQRFVFHKPVLAG
MLBr_01908|M.leprae_Br4923 DAIVAPLTFVTIFAKYVQLDFFRNVDVGMETMQIVQVDQRFVFHKPVLVG
MAV_4525|M.avium_104 DAIIAPLTFATIFAKLVQLDFFRHVDIGMETLVIVQVDQRFVFSKPIKAG
MMAR_0970|M.marinum_M GGIVAPMTFVSILAKLVQSDFFRNVDVGMETMQIVQVDQRFVFYKPVLAG
MUL_0722|M.ulcerans_Agy99 GGIVAPMTFVSILAKLVQSDFFRNVDVGMETMQIVQVDQRFVFYKPVLAG
MSMEG_1342|M.smegmatis_MC2_155 PALVAPLTFASTLALLVQQHFFMHVDVGMQTMQIVQVDQKFIYHKPLLAG
MAB_3896c|M.abscessus_ATCC_199 DGLVASLTFPAVMALLVQKEFFRTYDVGMETMQIVQTDQKFVYHRPLKEG
::* ** : :* :* .** *:*::*: ***.**:* : :*: *
Mflv_5119|M.gilvum_PYR-GCK DRLRGVMTILTVDERFGADIVTTRNVLTDDAGEVVMESFTTLMGHE-GDN
Mvan_1232|M.vanbaalenii_PYR-1 DRLRGALTILTVDERFGADIVTTRNVLTDDAGEIVMESFTTLMGHE-GDN
TH_1866|M.thermoresistible__bu DELHGTMYIESVDERFGADIVTTRNVCTDQNDEVVLEAFTTMMGHE-GDN
Mb0656|M.bovis_AF2122/97 DKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQ-GDG
Rv0637|M.tuberculosis_H37Rv DKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQ-GDG
MLBr_01908|M.leprae_Br4923 DKLWARMDIHSVSERFGADIVVTKNSCTSDDGELVMEAYTTLMGQQ-GDN
MAV_4525|M.avium_104 DKLWARMDIVSVDERFGADIVVTKNICTNDDGELVLEAYTTLMSQFNGDQ
MMAR_0970|M.marinum_M DKLWARMEVHSVDERFGADIVVTKNVCHNDDGEVVLEAYTTLMGQQ-GDG
MUL_0722|M.ulcerans_Agy99 DKLWARMEVHSVDERFGADIVVTKNVCHNDDGEVVLEAYTTLMGQQ-GDG
MSMEG_1342|M.smegmatis_MC2_155 DQLHAVMEIMSHEERFGADIVVTRNICTNDDGEVVLEAYTTLMGHE-GDN
MAB_3896c|M.abscessus_ATCC_199 DELSCDFEVESHKESFGVDIVTTRNVVRDQTGEVVLEAFTTLMGRD-SDR
*.* : : : .* **.***.*:* .: .*:*:*::**:*.: .*
Mflv_5119|M.gilvum_PYR-GCK SISAGWDPETGQVVRKPVKHDEDVAEDVPEDVTAAE
Mvan_1232|M.vanbaalenii_PYR-1 SISAGWDPETGQVLRKPVAHDP--ADDAGQ------
TH_1866|M.thermoresistible__bu SISAGWDPETGQVVRKPVVHDTD-------------
Mb0656|M.bovis_AF2122/97 SARLKWDKESGQVIRTA-------------------
Rv0637|M.tuberculosis_H37Rv SARLKWDKESGQVIRTA-------------------
MLBr_01908|M.leprae_Br4923 SSQLKWDKESGQVIRSA-------------------
MAV_4525|M.avium_104 SAKLRWDSESGQVVRTA-------------------
MMAR_0970|M.marinum_M SAKLKWDKETGQVIRTA-------------------
MUL_0722|M.ulcerans_Agy99 SAKLKWDKETGQVIRTA-------------------
MSMEG_1342|M.smegmatis_MC2_155 SISVKWDPETGQVIRKAIGE----------------
MAB_3896c|M.abscessus_ATCC_199 MADIKLI-----------------------------