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MTIISETEQATASELGAKANRHLWGHFARHGAGITPPIITRGEGVHIFDDKGKRYIDGLSGLFVVQVGHG RKELAEAAAKQAEQLAFFPLWSYATPTAVELAERLAGYAPGDLNRVFFTTGGGEAVESAWKLAKQYFKLT GKPGKHKVVSRSIAYHGTPQGALSITGIPAFKAPFEPLVPGGFRVPNTNFYRAPAEYAHDEKAFGRYCAD RIAEAIEFEGPETVAAVFLEPVQNAGGCFPPPPGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACED FGYVPDIITCAKGLTSGYSPIGAMIASDRLFEPFNDGSTVFGHGYTFGGHPVSSAVALANLDIFEREGLN ERVKQNAPAFRATLEQLLELPIVGDVRGEGYFYGIELVKDKATKETFNDEESERLLRGFLTPALWDAGLY CRADDRGDPVVQLAPPLISGQAEFDAIYDILRSVLTEASARM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4862 | - | - | 100% (462) | hypothetical protein Mflv_4862 |
| M. gilvum PYR-GCK | Mflv_0358 | - | 1e-57 | 35.79% (380) | hypothetical protein Mflv_0358 |
| M. gilvum PYR-GCK | Mflv_1055 | - | 3e-56 | 34.01% (397) | hypothetical protein Mflv_1055 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3362 | - | 0.0 | 79.82% (436) | hypothetical protein Mb3362 |
| M. tuberculosis H37Rv | Rv3329 | - | 0.0 | 79.59% (436) | hypothetical protein Rv3329 |
| M. leprae Br4923 | MLBr_01409 | argD | 7e-49 | 32.45% (453) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_3326c | - | 0.0 | 85.68% (454) | hypothetical protein MAB_3326c |
| M. marinum M | MMAR_3558 | - | 0.0 | 85.78% (450) | aminotransferase (adenosylmethionine-8-amino-7- oxononanoate) |
| M. avium 104 | MAV_4304 | - | 0.0 | 78.91% (441) | hypothetical protein MAV_4304 |
| M. smegmatis MC2 155 | MSMEG_1662 | - | 0.0 | 89.74% (458) | hypothetical protein MSMEG_1662 |
| M. thermoresistible (build 8) | TH_1978 | - | 0.0 | 80.76% (447) | PROBABLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_2791 | - | 0.0 | 85.78% (450) | hypothetical protein MUL_2791 |
| M. vanbaalenii PYR-1 | Mvan_1570 | - | 0.0 | 88.84% (448) | hypothetical protein Mvan_1570 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3362|M.bovis_AF2122/97 ------------------------MHFARHGAGIQHPVIVRGDGVTIFDD
Rv3329|M.tuberculosis_H37Rv ------------------------MHFARHGAGIQHPVIVRGDGVTIFDD
MAV_4304|M.avium_104 ------------------MTDHLWLHFARHGPGITPPIITRGHGVTIYDD
Mflv_4862|M.gilvum_PYR-GCK MTIISETEQATASELGAKANRHLWGHFARHGAGITPPIITRGEGVHIFDD
MSMEG_1662|M.smegmatis_MC2_155 -MTTADITQTAPTDLGAKANRHLWGHFARHGDGITPPIITRGEGVKIFDD
Mvan_1570|M.vanbaalenii_PYR-1 -MTTTDIAPQVSSDLEAKANRHLWGHFARHGKGITPPIITRGEGVHIWDS
MMAR_3558|M.marinum_M -----------MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDD
MUL_2791|M.ulcerans_Agy99 -----------MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDD
MAB_3326c|M.abscessus_ATCC_199 -MTSVDVVQDLSGDLHAKSSRHLWGHFARHGAGIAPPIITRGEGVRIWDD
TH_1978|M.thermoresistible__bu ----------MSTDRAAQADRHLWGHFARHGPGVTPPIIVRGDGVTIWDD
MLBr_01409|M.leprae_Br4923 ---------MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVTDV
. :. * ::. *.*. : *
Mb3362|M.bovis_AF2122/97 RGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIE
Rv3329|M.tuberculosis_H37Rv RGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIE
MAV_4304|M.avium_104 RGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAFFPLWGYATPPAIE
Mflv_4862|M.gilvum_PYR-GCK KGKRYIDGLSGLFVVQVGHGRKELAEAAAKQAEQLAFFPLWSYATPTAVE
MSMEG_1662|M.smegmatis_MC2_155 SGKSYIDGLSGLFVVQVGHGRKELAEAAAKQAEKLSFFPLWSYATPPAIE
Mvan_1570|M.vanbaalenii_PYR-1 TGRKYIDGLSGLFVVQAGHGRKELAEAAAKQAEQLAFFPLWSYATPTAIE
MMAR_3558|M.marinum_M RGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAFFPLWSYATPTAIE
MUL_2791|M.ulcerans_Agy99 RGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAFFPLWSYATPTAIE
MAB_3326c|M.abscessus_ATCC_199 RGKSYIDGLSGLFVVQAGHGRAELAQAAARQAEKLAYFPLWSYATEPAIE
TH_1978|M.thermoresistible__bu HGRRYLDGLSGLFVVQAGHGRAELAEAAARQAGQLAYFPLWSYATPPAIE
MLBr_01409|M.leprae_Br4923 DSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHTSNL-YATEPSIT
.. *:* *.*: . *: : : :*.::* *.. . *** .::
Mb3362|M.bovis_AF2122/97 LAERLARYAPGDLN-RVFFTSGGTEAVETAWKVAKQYFKLTGKPGKHKVI
Rv3329|M.tuberculosis_H37Rv LAERLARYAPGDLN-RVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVI
MAV_4304|M.avium_104 LAERLAGYAPGDLN-RVFFTTGGTEAVETAWKLAKQYFKLTGKPGKHKVI
Mflv_4862|M.gilvum_PYR-GCK LAERLAGYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV
MSMEG_1662|M.smegmatis_MC2_155 LAERVASFAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV
Mvan_1570|M.vanbaalenii_PYR-1 LADRLAHYAPADLN-RVFFTTGGGEAVESAWKLAKQYYKLVGKPGKFKVI
MMAR_3558|M.marinum_M LAERVAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAI
MUL_2791|M.ulcerans_Agy99 LAERVAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAI
MAB_3326c|M.abscessus_ATCC_199 LADRLAGYAPGDLN-RVFFTTGGGEAVESAWKLAKQFFKLTGKPGKHKVI
TH_1978|M.thermoresistible__bu LAERIAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV
MLBr_01409|M.leprae_Br4923 LAEELVALLGADTQTRVFFCNSGTEANELAFKLSR-------LTGRTKLV
**:.:. .* : **** ..* ** * *:*::: .*: * :
Mb3362|M.bovis_AF2122/97 SRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAP--LHT
Rv3329|M.tuberculosis_H37Rv SRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAP--LHT
MAV_4304|M.avium_104 SRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFRVPNTNFYRAPEAFAN
Mflv_4862|M.gilvum_PYR-GCK SRSIAYHGTPQGALSITGIPAFKAPFEPLVPGGFRVPNTNFYRAPAEYAH
MSMEG_1662|M.smegmatis_MC2_155 SRSIAYHGTPQGALAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPAEYAH
Mvan_1570|M.vanbaalenii_PYR-1 SRAIAYHGTPQGALAITGLPDFKKPFEPLTPGGFRVPNTNFYRAPAPYDT
MMAR_3558|M.marinum_M SRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYAD
MUL_2791|M.ulcerans_Agy99 SRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYAD
MAB_3326c|M.abscessus_ATCC_199 SRAIAYHGTPQGALAITGLPAFKAPFEPLTPGGFRAPNTNFYRAPEPYAH
TH_1978|M.thermoresistible__bu SRAVAYHGTPQGALAITGLPMFKAPFEPLTPGGFRVPNTNFYRAPAPYRD
MLBr_01409|M.leprae_Br4923 AAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYG-----------
: *:** . *:*::** * : .***: : *
Mb3362|M.bovis_AF2122/97 DLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERV
Rv3329|M.tuberculosis_H37Rv DLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERV
MAV_4304|M.avium_104 DPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERV
Mflv_4862|M.gilvum_PYR-GCK DEKAFGRYCADRIAEAIEFEGPETVAAVFLEPVQNAGGCFPPPPGYFERV
MSMEG_1662|M.smegmatis_MC2_155 DEKAFGRYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
Mvan_1570|M.vanbaalenii_PYR-1 DPKAWGRYCADRIAEAIEFEGPDTVCAVFLEPVQNAGGCFPPPPGYFERV
MMAR_3558|M.marinum_M DSKEFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
MUL_2791|M.ulcerans_Agy99 DSKDFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
MAB_3326c|M.abscessus_ATCC_199 DSKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
TH_1978|M.thermoresistible__bu DEKAFGRYCADRIAETIEFEGPDTVAAVVLEPVQNAGGCIPPPPGYFERV
MLBr_01409|M.leprae_Br4923 --------QVDALAAAVDN----DTAAVFLEPIMGESGVIVPPEGYLAAA
.: :* ::: ..**.:**: . .* : .* **: .
Mb3362|M.bovis_AF2122/97 REICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYS
Rv3329|M.tuberculosis_H37Rv REICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYS
MAV_4304|M.avium_104 REICDRYDVLLVSDEVICAFGRIGSMFACADFGYVPDMITCAKGMTSGYS
Mflv_4862|M.gilvum_PYR-GCK REICDEYDVLLVSDEVICAYGRIGSMFACEDFGYVPDIITCAKGLTSGYS
MSMEG_1662|M.smegmatis_MC2_155 REICDEYDVLLVSDEVICAYGRIGSMFACNDFGYVPDIITSAKGLTSGYS
Mvan_1570|M.vanbaalenii_PYR-1 REICDEYDVLLVSDEVICAFGRIGSMFACDDFGYVPDIITCAKGLTSGYS
MMAR_3558|M.marinum_M REICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCAKGMTSGYS
MUL_2791|M.ulcerans_Agy99 REICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCAKGMTSGYS
MAB_3326c|M.abscessus_ATCC_199 REICDEYDVLLVSDEVICAFGRIGSMFACEDFGYQPDIVTCAKGMTSGYS
TH_1978|M.thermoresistible__bu REICDTYDVLLISDEVICAFGRIGSMFACDDFGYQPDIITCAKGLTSGYA
MLBr_01409|M.leprae_Br4923 RDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDVVTLAKGLGGG-L
*:* :..**: *** . ** *::** . . **::* ***: .*
Mb3362|M.bovis_AF2122/97 PLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGL
Rv3329|M.tuberculosis_H37Rv PLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGL
MAV_4304|M.avium_104 PIGAMIASERLFEPFADGDTMFPHGYTFGGHPVSAAVGLVNLDIFEREGL
Mflv_4862|M.gilvum_PYR-GCK PIGAMIASDRLFEPFNDGSTVFGHGYTFGGHPVSSAVALANLDIFEREGL
MSMEG_1662|M.smegmatis_MC2_155 PLGAMVASDRLFEPFNDGKTVFGHGYTFGGHPVSAAVAMANLDIFEREGI
Mvan_1570|M.vanbaalenii_PYR-1 PIGAMIASDRLFEPFNDGKTVFGHGYTFGGHPVSSAVALANLDIFEREGL
MMAR_3558|M.marinum_M PIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGL
MUL_2791|M.ulcerans_Agy99 PIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGL
MAB_3326c|M.abscessus_ATCC_199 PIGAMIATDRLFEPFNDGKTTFPHGYTFGGHPVSAAVALANLDIFEREGL
TH_1978|M.thermoresistible__bu PLGAMIATDRLFEPFADGKTVFPHGYTFGGHPVSAAVALANLDIFEREGL
MLBr_01409|M.leprae_Br4923 PIGAFLATGPAAELLTLG----LHGSTFGGNPVCTAAALAVLRVLATQGL
*:**::*: * : * ** ****:**.:*..:. * :: :*:
Mb3362|M.bovis_AF2122/97 SDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTD
Rv3329|M.tuberculosis_H37Rv SDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTD
MAV_4304|M.avium_104 NDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYGVELVKDRATKQTFTD
Mflv_4862|M.gilvum_PYR-GCK NERVKQNAPAFRATLEQLLELPIVGDVRGEGYFYGIELVKDKATKETFND
MSMEG_1662|M.smegmatis_MC2_155 NDHVKTMAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKTTKETFND
Mvan_1570|M.vanbaalenii_PYR-1 NAHVKDNAPVFRATLEQLLELPIVGDVRGEGFFYGIELVKDKATKETFNE
MMAR_3558|M.marinum_M NDHVKQNAPAFRTTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSD
MUL_2791|M.ulcerans_Agy99 NDHVKQNAPAFRTTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSD
MAB_3326c|M.abscessus_ATCC_199 NDRVRENAPVFRATLEKLYDLPIVGDVRGEGYFYGIELVKDKAAKTTFSD
TH_1978|M.thermoresistible__bu NDRVRTLSPLLRATLERLYELPIVGDVRGEGYFFAVELVQDKAGRQPFSA
MLBr_01409|M.leprae_Br4923 VRRAEVLGDSMRIGIESLS-HPLIDQVRGRGLLLGIVLTAPRAKD-----
:.. . :* :* * *::.::**.* : .: *. :
Mb3362|M.bovis_AF2122/97 DERARLLG-QVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIET
Rv3329|M.tuberculosis_H37Rv DERARLLG-QVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIET
MAV_4304|M.avium_104 SERRALLG-RVGAALFEAGLYCRTDDRGDSVIQLAPPLISGQAEFDTIEA
Mflv_4862|M.gilvum_PYR-GCK EESERLLRGFLTPALWDAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYD
MSMEG_1662|M.smegmatis_MC2_155 EESERLLRGFLTPALWEAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYD
Mvan_1570|M.vanbaalenii_PYR-1 DESERLLRGFLTSALFEGGLYCRADDRGDPVVQLAPPLISGKKEFDAIYD
MMAR_3558|M.marinum_M EESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAPPLISGQQEFDKMEQ
MUL_2791|M.ulcerans_Agy99 EESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAPPLISGQQEFDKMEQ
MAB_3326c|M.abscessus_ATCC_199 EESERLLRGFLSAALWDAGLYCRADDRGDPVIQLAPPLISGPREFEAIEQ
TH_1978|M.thermoresistible__bu EESARLVA-HLNRALLDAGLYCRADNRGDTVVQVAPPLISGPAEFDAMHD
MLBr_01409|M.leprae_Br4923 ----------IEKAARDAGFLVNATAP--EVIRLAPPLIITESQIDSFIT
: * :.*: .: *:::***** ::: :
Mb3362|M.bovis_AF2122/97 ILRSVLTDTGRKYLHL-
Rv3329|M.tuberculosis_H37Rv ILRSVLTDTGRKYLHL-
MAV_4304|M.avium_104 ALRGVLSDECRRL----
Mflv_4862|M.gilvum_PYR-GCK ILRSVLTEASARM----
MSMEG_1662|M.smegmatis_MC2_155 ILHNVLTEAGNRL----
Mvan_1570|M.vanbaalenii_PYR-1 ILHRVLSEASRML----
MMAR_3558|M.marinum_M ILRGVLSEAWSRL----
MUL_2791|M.ulcerans_Agy99 ILRGVLSEAWSRL----
MAB_3326c|M.abscessus_ATCC_199 ILRGVLTEAWARL----
TH_1978|M.thermoresistible__bu ILRTVLKDAPNHV----
MLBr_01409|M.leprae_Br4923 ALPGILDASIAELGKKA
* :*