For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTADITQTAPTDLGAKANRHLWGHFARHGDGITPPIITRGEGVKIFDDSGKSYIDGLSGLFVVQVGHGRK ELAEAAAKQAEKLSFFPLWSYATPPAIELAERVASFAPGDLNRVFFTTGGGEAVESAWKLAKQYFKLTGK PGKHKVVSRSIAYHGTPQGALAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPAEYAHDEKAFGRYCADRI AEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACNDFG YVPDIITSAKGLTSGYSPLGAMVASDRLFEPFNDGKTVFGHGYTFGGHPVSAAVAMANLDIFEREGINDH VKTMAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKTTKETFNDEESERLLRGFLTPALWEAGLYCR ADDRGDPVVQLAPPLISGQAEFDAIYDILHNVLTEAGNRL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1662 | - | - | 100% (461) | hypothetical protein MSMEG_1662 |
M. smegmatis MC2 155 | MSMEG_2450 | - | 4e-57 | 35.44% (364) | hypothetical protein MSMEG_2450 |
M. smegmatis MC2 155 | MSMEG_3773 | argD | 1e-47 | 34.59% (425) | acetylornithine aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3362 | - | 0.0 | 80.05% (436) | hypothetical protein Mb3362 |
M. gilvum PYR-GCK | Mflv_4862 | - | 0.0 | 89.74% (458) | hypothetical protein Mflv_4862 |
M. tuberculosis H37Rv | Rv3329 | - | 0.0 | 79.82% (436) | hypothetical protein Rv3329 |
M. leprae Br4923 | MLBr_01409 | argD | 5e-49 | 32.58% (445) | acetylornithine aminotransferase |
M. abscessus ATCC 19977 | MAB_3326c | - | 0.0 | 84.38% (461) | hypothetical protein MAB_3326c |
M. marinum M | MMAR_3558 | - | 0.0 | 86.44% (450) | aminotransferase (adenosylmethionine-8-amino-7- oxononanoate) |
M. avium 104 | MAV_4304 | - | 0.0 | 79.37% (441) | hypothetical protein MAV_4304 |
M. thermoresistible (build 8) | TH_1978 | - | 0.0 | 80.00% (450) | PROBABLE AMINOTRANSFERASE |
M. ulcerans Agy99 | MUL_2791 | - | 0.0 | 86.44% (450) | hypothetical protein MUL_2791 |
M. vanbaalenii PYR-1 | Mvan_1570 | - | 0.0 | 85.47% (461) | hypothetical protein Mvan_1570 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3362|M.bovis_AF2122/97 ------------------------MHFARHGAGIQHPVIVRGDGVTIFDD Rv3329|M.tuberculosis_H37Rv ------------------------MHFARHGAGIQHPVIVRGDGVTIFDD MAV_4304|M.avium_104 ------------------MTDHLWLHFARHGPGITPPIITRGHGVTIYDD MSMEG_1662|M.smegmatis_MC2_155 -MTTADITQTAPTDLGAKANRHLWGHFARHGDGITPPIITRGEGVKIFDD Mflv_4862|M.gilvum_PYR-GCK MTIISETEQATASELGAKANRHLWGHFARHGAGITPPIITRGEGVHIFDD Mvan_1570|M.vanbaalenii_PYR-1 -MTTTDIAPQVSSDLEAKANRHLWGHFARHGKGITPPIITRGEGVHIWDS MMAR_3558|M.marinum_M -----------MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDD MUL_2791|M.ulcerans_Agy99 -----------MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDD MAB_3326c|M.abscessus_ATCC_199 -MTSVDVVQDLSGDLHAKSSRHLWGHFARHGAGIAPPIITRGEGVRIWDD TH_1978|M.thermoresistible__bu ----------MSTDRAAQADRHLWGHFARHGPGVTPPIIVRGDGVTIWDD MLBr_01409|M.leprae_Br4923 ---------MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVTDV . :. * ::. *.*. : * Mb3362|M.bovis_AF2122/97 RGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIE Rv3329|M.tuberculosis_H37Rv RGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIE MAV_4304|M.avium_104 RGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAFFPLWGYATPPAIE MSMEG_1662|M.smegmatis_MC2_155 SGKSYIDGLSGLFVVQVGHGRKELAEAAAKQAEKLSFFPLWSYATPPAIE Mflv_4862|M.gilvum_PYR-GCK KGKRYIDGLSGLFVVQVGHGRKELAEAAAKQAEQLAFFPLWSYATPTAVE Mvan_1570|M.vanbaalenii_PYR-1 TGRKYIDGLSGLFVVQAGHGRKELAEAAAKQAEQLAFFPLWSYATPTAIE MMAR_3558|M.marinum_M RGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAFFPLWSYATPTAIE MUL_2791|M.ulcerans_Agy99 RGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAFFPLWSYATPTAIE MAB_3326c|M.abscessus_ATCC_199 RGKSYIDGLSGLFVVQAGHGRAELAQAAARQAEKLAYFPLWSYATEPAIE TH_1978|M.thermoresistible__bu HGRRYLDGLSGLFVVQAGHGRAELAEAAARQAGQLAYFPLWSYATPPAIE MLBr_01409|M.leprae_Br4923 DSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHTSNL-YATEPSIT .. *:* *.*: . *: : : :*.::* *.. . *** .:: Mb3362|M.bovis_AF2122/97 LAERLARYAPGDLN-RVFFTSGGTEAVETAWKVAKQYFKLTGKPGKHKVI Rv3329|M.tuberculosis_H37Rv LAERLARYAPGDLN-RVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVI MAV_4304|M.avium_104 LAERLAGYAPGDLN-RVFFTTGGTEAVETAWKLAKQYFKLTGKPGKHKVI MSMEG_1662|M.smegmatis_MC2_155 LAERVASFAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV Mflv_4862|M.gilvum_PYR-GCK LAERLAGYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV Mvan_1570|M.vanbaalenii_PYR-1 LADRLAHYAPADLN-RVFFTTGGGEAVESAWKLAKQYYKLVGKPGKFKVI MMAR_3558|M.marinum_M LAERVAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAI MUL_2791|M.ulcerans_Agy99 LAERVAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAI MAB_3326c|M.abscessus_ATCC_199 LADRLAGYAPGDLN-RVFFTTGGGEAVESAWKLAKQFFKLTGKPGKHKVI TH_1978|M.thermoresistible__bu LAERIAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV MLBr_01409|M.leprae_Br4923 LAEELVALLGADTQTRVFFCNSGTEANELAFKLSR-------LTGRTKLV **:.:. .* : **** ..* ** * *:*::: .*: * : Mb3362|M.bovis_AF2122/97 SRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAP--LHT Rv3329|M.tuberculosis_H37Rv SRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAP--LHT MAV_4304|M.avium_104 SRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFRVPNTNFYRAPEAFAN MSMEG_1662|M.smegmatis_MC2_155 SRSIAYHGTPQGALAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPAEYAH Mflv_4862|M.gilvum_PYR-GCK SRSIAYHGTPQGALSITGIPAFKAPFEPLVPGGFRVPNTNFYRAPAEYAH Mvan_1570|M.vanbaalenii_PYR-1 SRAIAYHGTPQGALAITGLPDFKKPFEPLTPGGFRVPNTNFYRAPAPYDT MMAR_3558|M.marinum_M SRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYAD MUL_2791|M.ulcerans_Agy99 SRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYAD MAB_3326c|M.abscessus_ATCC_199 SRAIAYHGTPQGALAITGLPAFKAPFEPLTPGGFRAPNTNFYRAPEPYAH TH_1978|M.thermoresistible__bu SRAVAYHGTPQGALAITGLPMFKAPFEPLTPGGFRVPNTNFYRAPAPYRD MLBr_01409|M.leprae_Br4923 AAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYG----------- : *:** . *:*::** * : .***: : * Mb3362|M.bovis_AF2122/97 DLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERV Rv3329|M.tuberculosis_H37Rv DLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERV MAV_4304|M.avium_104 DPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERV MSMEG_1662|M.smegmatis_MC2_155 DEKAFGRYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV Mflv_4862|M.gilvum_PYR-GCK DEKAFGRYCADRIAEAIEFEGPETVAAVFLEPVQNAGGCFPPPPGYFERV Mvan_1570|M.vanbaalenii_PYR-1 DPKAWGRYCADRIAEAIEFEGPDTVCAVFLEPVQNAGGCFPPPPGYFERV MMAR_3558|M.marinum_M DSKEFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV MUL_2791|M.ulcerans_Agy99 DSKDFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV MAB_3326c|M.abscessus_ATCC_199 DSKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV TH_1978|M.thermoresistible__bu DEKAFGRYCADRIAETIEFEGPDTVAAVVLEPVQNAGGCIPPPPGYFERV MLBr_01409|M.leprae_Br4923 --------QVDALAAAVDN----DTAAVFLEPIMGESGVIVPPEGYLAAA .: :* ::: ..**.:**: . .* : .* **: . Mb3362|M.bovis_AF2122/97 REICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYS Rv3329|M.tuberculosis_H37Rv REICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYS MAV_4304|M.avium_104 REICDRYDVLLVSDEVICAFGRIGSMFACADFGYVPDMITCAKGMTSGYS MSMEG_1662|M.smegmatis_MC2_155 REICDEYDVLLVSDEVICAYGRIGSMFACNDFGYVPDIITSAKGLTSGYS Mflv_4862|M.gilvum_PYR-GCK REICDEYDVLLVSDEVICAYGRIGSMFACEDFGYVPDIITCAKGLTSGYS Mvan_1570|M.vanbaalenii_PYR-1 REICDEYDVLLVSDEVICAFGRIGSMFACDDFGYVPDIITCAKGLTSGYS MMAR_3558|M.marinum_M REICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCAKGMTSGYS MUL_2791|M.ulcerans_Agy99 REICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCAKGMTSGYS MAB_3326c|M.abscessus_ATCC_199 REICDEYDVLLVSDEVICAFGRIGSMFACEDFGYQPDIVTCAKGMTSGYS TH_1978|M.thermoresistible__bu REICDTYDVLLISDEVICAFGRIGSMFACDDFGYQPDIITCAKGLTSGYA MLBr_01409|M.leprae_Br4923 RDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDVVTLAKGLGGG-L *:* :..**: *** . ** *::** . . **::* ***: .* Mb3362|M.bovis_AF2122/97 PLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGL Rv3329|M.tuberculosis_H37Rv PLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGL MAV_4304|M.avium_104 PIGAMIASERLFEPFADGDTMFPHGYTFGGHPVSAAVGLVNLDIFEREGL MSMEG_1662|M.smegmatis_MC2_155 PLGAMVASDRLFEPFNDGKTVFGHGYTFGGHPVSAAVAMANLDIFEREGI Mflv_4862|M.gilvum_PYR-GCK PIGAMIASDRLFEPFNDGSTVFGHGYTFGGHPVSSAVALANLDIFEREGL Mvan_1570|M.vanbaalenii_PYR-1 PIGAMIASDRLFEPFNDGKTVFGHGYTFGGHPVSSAVALANLDIFEREGL MMAR_3558|M.marinum_M PIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGL MUL_2791|M.ulcerans_Agy99 PIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGL MAB_3326c|M.abscessus_ATCC_199 PIGAMIATDRLFEPFNDGKTTFPHGYTFGGHPVSAAVALANLDIFEREGL TH_1978|M.thermoresistible__bu PLGAMIATDRLFEPFADGKTVFPHGYTFGGHPVSAAVALANLDIFEREGL MLBr_01409|M.leprae_Br4923 PIGAFLATGPAAELLTLG----LHGSTFGGNPVCTAAALAVLRVLATQGL *:**::*: * : * ** ****:**.:*..:. * :: :*: Mb3362|M.bovis_AF2122/97 SDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTD Rv3329|M.tuberculosis_H37Rv SDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTD MAV_4304|M.avium_104 NDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYGVELVKDRATKQTFTD MSMEG_1662|M.smegmatis_MC2_155 NDHVKTMAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKTTKETFND Mflv_4862|M.gilvum_PYR-GCK NERVKQNAPAFRATLEQLLELPIVGDVRGEGYFYGIELVKDKATKETFND Mvan_1570|M.vanbaalenii_PYR-1 NAHVKDNAPVFRATLEQLLELPIVGDVRGEGFFYGIELVKDKATKETFNE MMAR_3558|M.marinum_M NDHVKQNAPAFRTTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSD MUL_2791|M.ulcerans_Agy99 NDHVKQNAPAFRTTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSD MAB_3326c|M.abscessus_ATCC_199 NDRVRENAPVFRATLEKLYDLPIVGDVRGEGYFYGIELVKDKAAKTTFSD TH_1978|M.thermoresistible__bu NDRVRTLSPLLRATLERLYELPIVGDVRGEGYFFAVELVQDKAGRQPFSA MLBr_01409|M.leprae_Br4923 VRRAEVLGDSMRIGIESLS-HPLIDQVRGRGLLLGIVLTAPRAKD----- :.. . :* :* * *::.::**.* : .: *. : Mb3362|M.bovis_AF2122/97 DERARLLG-QVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIET Rv3329|M.tuberculosis_H37Rv DERARLLG-QVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIET MAV_4304|M.avium_104 SERRALLG-RVGAALFEAGLYCRTDDRGDSVIQLAPPLISGQAEFDTIEA MSMEG_1662|M.smegmatis_MC2_155 EESERLLRGFLTPALWEAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYD Mflv_4862|M.gilvum_PYR-GCK EESERLLRGFLTPALWDAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYD Mvan_1570|M.vanbaalenii_PYR-1 DESERLLRGFLTSALFEGGLYCRADDRGDPVVQLAPPLISGKKEFDAIYD MMAR_3558|M.marinum_M EESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAPPLISGQQEFDKMEQ MUL_2791|M.ulcerans_Agy99 EESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAPPLISGQQEFDKMEQ MAB_3326c|M.abscessus_ATCC_199 EESERLLRGFLSAALWDAGLYCRADDRGDPVIQLAPPLISGPREFEAIEQ TH_1978|M.thermoresistible__bu EESARLVA-HLNRALLDAGLYCRADNRGDTVVQVAPPLISGPAEFDAMHD MLBr_01409|M.leprae_Br4923 ----------IEKAARDAGFLVNATAP--EVIRLAPPLIITESQIDSFIT : * :.*: .: *:::***** ::: : Mb3362|M.bovis_AF2122/97 ILRSVLTDTGRKYLHL- Rv3329|M.tuberculosis_H37Rv ILRSVLTDTGRKYLHL- MAV_4304|M.avium_104 ALRGVLSDECRRL---- MSMEG_1662|M.smegmatis_MC2_155 ILHNVLTEAGNRL---- Mflv_4862|M.gilvum_PYR-GCK ILRSVLTEASARM---- Mvan_1570|M.vanbaalenii_PYR-1 ILHRVLSEASRML---- MMAR_3558|M.marinum_M ILRGVLSEAWSRL---- MUL_2791|M.ulcerans_Agy99 ILRGVLSEAWSRL---- MAB_3326c|M.abscessus_ATCC_199 ILRGVLTEAWARL---- TH_1978|M.thermoresistible__bu ILRTVLKDAPNHV---- MLBr_01409|M.leprae_Br4923 ALPGILDASIAELGKKA * :*