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MSAPVLDKQDTPPVPEGAVMVTLKIARFNPESPDDAGWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRR SCAHGVCGSDAMRINGVNRLACKVLMRDMLPKNPNKQLTITIEPIRGLPVEKDLVVDMEPFFDAFRAVKP YLITSGNQPTRERIQSQTDRARYDDTTKCILCACCTTSCPVYWSEGSYFGPAAIVNAHRFIFDSRDEAAA ERLDILNDIDGVWRCRTTFNCTEACPRGIQVTKAIQEVKRALMFAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4847 | sdhB | - | 100% (256) | succinate dehydrogenase iron-sulfur subunit |
| M. gilvum PYR-GCK | Mflv_0395 | - | 1e-15 | 27.44% (215) | fumarate reductase iron-sulfur subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3348 | sdhB | 1e-131 | 87.55% (249) | succinate dehydrogenase iron-sulfur subunit |
| M. tuberculosis H37Rv | Rv3319 | sdhB | 1e-131 | 87.55% (249) | succinate dehydrogenase iron-sulfur subunit |
| M. leprae Br4923 | MLBr_00696 | sdhB | 1e-127 | 83.94% (249) | succinate dehydrogenase iron-sulfur subunit |
| M. abscessus ATCC 19977 | MAB_3676 | sdhB | 1e-134 | 91.02% (245) | succinate dehydrogenase iron-sulfur subunit |
| M. marinum M | MMAR_1200 | sdhB | 1e-132 | 88.35% (249) | succinate dehydrogenase (iron-sulphur protein subunit) SdhB |
| M. avium 104 | MAV_4300 | sdhB | 1e-126 | 83.40% (253) | succinate dehydrogenase iron-sulfur subunit |
| M. smegmatis MC2 155 | MSMEG_1669 | sdhB | 1e-144 | 91.95% (261) | succinate dehydrogenase iron-sulfur subunit |
| M. thermoresistible (build 8) | TH_2183 | sdhB | 1e-136 | 87.60% (258) | PROBABLE SUCCINATE DEHYDROGENASE (IRON-SULPHUR PROTEIN |
| M. ulcerans Agy99 | MUL_1370 | sdhB | 1e-130 | 86.35% (249) | succinate dehydrogenase iron-sulfur subunit |
| M. vanbaalenii PYR-1 | Mvan_1586 | sdhB | 1e-148 | 96.09% (256) | succinate dehydrogenase iron-sulfur subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1200|M.marinum_M MSLDTERASSDDVTDSLAPPLPPVPDGAVMVTVKIARFNPDDPEAFASTG
MUL_1370|M.ulcerans_Agy99 --MDTERASSDDVTDSLAPPLPPVPDGAVMVTVKIARYNPDDPEAFASTG
Mb3348|M.bovis_AF2122/97 --MSVEP-----DVETLDPPLPPVPDGAVMVTVKIARFNPDEPDAFAATG
Rv3319|M.tuberculosis_H37Rv --MSVEP-----DVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATG
MAV_4300|M.avium_104 --MSVEP-----DVETLEPPLPPVPDEAVMVTVKIARFNPDQPDAYAETG
MLBr_00696|M.leprae_Br4923 --MAVEPV----EVKSLEPPRPPISDDAVMVTVKIARFNPDNPDAFAETG
Mflv_4847|M.gilvum_PYR-GCK ---MSAPV--LDKQ-----DTPPVPEGAVMVTLKIARFNPESPDD----A
Mvan_1586|M.vanbaalenii_PYR-1 ---MSAPT--LEKA-----ELPPVPEGAVMVTLKIARFNPESPDD----A
MSMEG_1669|M.smegmatis_MC2_155 ---MSAPV--IDKPEAGDPELPPVPEGAVMVTLKIARFNPENPDA----A
TH_2183|M.thermoresistible__bu --MTITPD--IDKPATTDAPLPPVPEGAVMVTLKIARFNPENPDA----A
MAB_3676|M.abscessus_ATCC_1997 ----MTAV--IEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDA----A
**:.: **** :** *:**:.*: .
MMAR_1200|M.marinum_M GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
MUL_1370|M.ulcerans_Agy99 GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
Mb3348|M.bovis_AF2122/97 GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
Rv3319|M.tuberculosis_H37Rv GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
MAV_4300|M.avium_104 GWQSFRVPCLPSDRMLNLLIYIKSYLDGTLTFRRSCAHGVCGSDAMRING
MLBr_00696|M.leprae_Br4923 GWQSFRVPCLPTDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRVNG
Mflv_4847|M.gilvum_PYR-GCK GWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRING
Mvan_1586|M.vanbaalenii_PYR-1 GWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRING
MSMEG_1669|M.smegmatis_MC2_155 GWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRING
TH_2183|M.thermoresistible__bu GFQSFRVPTLPTDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRVNG
MAB_3676|M.abscessus_ATCC_1997 GWQTFRVPCLPTDRLLNLLLYVKGYLDGTLTFRRSCAHGVCGSDAMRING
*:*:**** **:**:**** *:* ***********************:**
MMAR_1200|M.marinum_M VNRLACKVLMRDLLPKKP----GKQLTLTVEPIRGLPVEKDLVVDMEPFF
MUL_1370|M.ulcerans_Agy99 VNRLACKVLMRDLLPKKS----GKQLTLTVEPIRGLPVEKDLVVDMEPFF
Mb3348|M.bovis_AF2122/97 VNRLACKVLMRDLLPKKK----GKSLTVTVEPIRGLPVEKDLVVDMEPFF
Rv3319|M.tuberculosis_H37Rv VNRLACKVLMRDLLPKKK----GKSLTVTVEPIRGLPVEKDLVVDMEPFF
MAV_4300|M.avium_104 VNRLACKVLMRDLLPEPKKGKPGKPLTITVEPIRGLPVEKDLVVDMEPFF
MLBr_00696|M.leprae_Br4923 VNRLACKVLMRDLLPKKA----GKNLTITVEPIRGLPVEKDLVVDMEPFF
Mflv_4847|M.gilvum_PYR-GCK VNRLACKVLMRDMLPKNP----NKQLTITIEPIRGLPVEKDLVVDMEPFF
Mvan_1586|M.vanbaalenii_PYR-1 VNRLACKVLMRDMLPKNP----KKQLTITIEPIRGLPVEKDLVVDMEPFF
MSMEG_1669|M.smegmatis_MC2_155 VNRLACKVLMRDMLPKNP----NKQLTITIEPIRGLPVEKDLVVNMEPFF
TH_2183|M.thermoresistible__bu VNRLACKVLMRDLLPKNP----KKELTVTVEPIRGLPVEKDLVVDMEPFF
MAB_3676|M.abscessus_ATCC_1997 VNRLACKVLMRDLLPKNP----KKTLTITIEPIRGLPVEKDLVVNMEPFF
************:**: * **:*:**************:*****
MMAR_1200|M.marinum_M DAYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
MUL_1370|M.ulcerans_Agy99 DAYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
Mb3348|M.bovis_AF2122/97 DAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
Rv3319|M.tuberculosis_H37Rv DAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
MAV_4300|M.avium_104 DAYRAVKPYLITTGNPPTRERIQSPADRARYDDTTKCILCAACTTSCPIF
MLBr_00696|M.leprae_Br4923 DAYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
Mflv_4847|M.gilvum_PYR-GCK DAFRAVKPYLITSGNQPTRERIQSQTDRARYDDTTKCILCACCTTSCPVY
Mvan_1586|M.vanbaalenii_PYR-1 DAFRAIKPYLITSGNQPTRERIQSQTDRARYDDTTKCILCACCTTSCPVY
MSMEG_1669|M.smegmatis_MC2_155 DAYRAVKPFLVTSGNPPTKERIQSPTDRARYDDTTKCILCACCTTSCPVY
TH_2183|M.thermoresistible__bu DAYRAVKPFLVTSGNPPTRERLQSPQDRARYDDTTKCILCACCTTSCPVY
MAB_3676|M.abscessus_ATCC_1997 DAYRAVKPFMITSGNQPTREYIQSQTDRARFDDTTKCILCACCTTSCPVF
**:**:**:::*:** **:* :** ****:**********.******::
MMAR_1200|M.marinum_M WNEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
MUL_1370|M.ulcerans_Agy99 WNEGSYLGPAAIVNAHRFIFDSRDEAAAERVDILNEVDGVWRCRTTFNCT
Mb3348|M.bovis_AF2122/97 WHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
Rv3319|M.tuberculosis_H37Rv WHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
MAV_4300|M.avium_104 WHEGSYYGPAAIVNAHRFIFDSRDEGAAERLDILNEVDGVWRCRTTFNCT
MLBr_00696|M.leprae_Br4923 WSEGTYYGPAAIVNAHRFIFDSRDEGAGERLTLLNEVDGVWRCRTTFNCT
Mflv_4847|M.gilvum_PYR-GCK WSEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDIDGVWRCRTTFNCT
Mvan_1586|M.vanbaalenii_PYR-1 WNEGSYFGPAAIVNAHRFIFDSRDEGAAERLDILNDVDGVWRCRTTFNCT
MSMEG_1669|M.smegmatis_MC2_155 WSEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
TH_2183|M.thermoresistible__bu WTEGSYFGPAAIVNAHRFIFDSRDEAAGERLDILNEVDGVWRCRTTFNCT
MAB_3676|M.abscessus_ATCC_1997 WSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCT
* :*:* ******************.*.**: :**::*************
MMAR_1200|M.marinum_M EACPRGIEVTKAIQEVKRALLFSR
MUL_1370|M.ulcerans_Agy99 EACPRGIEATKAIQEVKRALLFSR
Mb3348|M.bovis_AF2122/97 ESCPRGIEVTKAIQEVKRALMFTR
Rv3319|M.tuberculosis_H37Rv ESCPRGIEVTKAIQEVKRALMFTR
MAV_4300|M.avium_104 DACPRGIEVTKAIQEVKRAIMFSR
MLBr_00696|M.leprae_Br4923 ESCPRNIEVTKAIQEVKRALMFSR
Mflv_4847|M.gilvum_PYR-GCK EACPRGIQVTKAIQEVKRALMFAR
Mvan_1586|M.vanbaalenii_PYR-1 EACPRGIQVTKAIQEVKRALMFAR
MSMEG_1669|M.smegmatis_MC2_155 EACPRGIQVTQAIQEVKRALMFAR
TH_2183|M.thermoresistible__bu ESCPRGIQVTKAIQEVKRALMFAR
MAB_3676|M.abscessus_ATCC_1997 DACPRGIEVTKAIQEVKRALMFAR
::***.*:.*:********::*:*