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M. leprae Br4923 MLBr_00696 (sdhB)

annotation: succinate dehydrogenase iron-sulfur subunit
coordinates: 833881 - 834675
length: 264

AVEPVEVKSLEPPRPPISDDAVMVTVKIARFNPDNPDAFAETGGWQSFRVPCLPTDRLLNLLIYIKGYLD
GTLTFRRSCAHGVCGSDAMRVNGVNRLACKVLMRDLLPKKAGKNLTITVEPIRGLPVEKDLVVDMEPFFD
AYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVFWSEGTYYGPAAIVNAHRFIFD
SRDEGAGERLTLLNEVDGVWRCRTTFNCTESCPRNIEVTKAIQEVKRALMFSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00696sdhB-100% (264)succinate dehydrogenase iron-sulfur subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3348sdhB1e-14389.77% (264) succinate dehydrogenase iron-sulfur subunit
M. gilvum PYR-GCKMflv_4847sdhB1e-12783.94% (249) succinate dehydrogenase iron-sulfur subunit
M. tuberculosis H37RvRv3319sdhB1e-14389.77% (264) succinate dehydrogenase iron-sulfur subunit
M. abscessus ATCC 19977MAB_3676sdhB1e-12782.61% (253) succinate dehydrogenase iron-sulfur subunit
M. marinum MMMAR_1200sdhB1e-14190.98% (255) succinate dehydrogenase (iron-sulphur protein subunit) SdhB
M. avium 104MAV_4300sdhB1e-13986.94% (268) succinate dehydrogenase iron-sulfur subunit
M. smegmatis MC2 155MSMEG_1669sdhB1e-12983.79% (253) succinate dehydrogenase iron-sulfur subunit
M. thermoresistible (build 8)TH_2183sdhB1e-12984.98% (253) PROBABLE SUCCINATE DEHYDROGENASE (IRON-SULPHUR PROTEIN
M. ulcerans Agy99MUL_1370sdhB1e-13989.80% (255) succinate dehydrogenase iron-sulfur subunit
M. vanbaalenii PYR-1Mvan_1586sdhB1e-12783.94% (249) succinate dehydrogenase iron-sulfur subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mb3348|M.bovis_AF2122/97            --MSVEP-----DVETLDPPLPPVPDGAVMVTVKIARFNPDEPDAFAATG
Rv3319|M.tuberculosis_H37Rv         --MSVEP-----DVETLDPPLPPVPDGAVMVTVKIARFNPDDPDAFAATG
MAV_4300|M.avium_104                --MSVEP-----DVETLEPPLPPVPDEAVMVTVKIARFNPDQPDAYAETG
MLBr_00696|M.leprae_Br4923          --MAVEPV----EVKSLEPPRPPISDDAVMVTVKIARFNPDNPDAFAETG
MMAR_1200|M.marinum_M               MSLDTERASSDDVTDSLAPPLPPVPDGAVMVTVKIARFNPDDPEAFASTG
MUL_1370|M.ulcerans_Agy99           --MDTERASSDDVTDSLAPPLPPVPDGAVMVTVKIARYNPDDPEAFASTG
Mflv_4847|M.gilvum_PYR-GCK          ---MSAPV--LDKQ-----DTPPVPEGAVMVTLKIARFNPESPDD----A
Mvan_1586|M.vanbaalenii_PYR-1       ---MSAPT--LEKA-----ELPPVPEGAVMVTLKIARFNPESPDD----A
MSMEG_1669|M.smegmatis_MC2_155      ---MSAPV--IDKPEAGDPELPPVPEGAVMVTLKIARFNPENPDA----A
TH_2183|M.thermoresistible__bu      --MTITPD--IDKPATTDAPLPPVPEGAVMVTLKIARFNPENPDA----A
MAB_3676|M.abscessus_ATCC_1997      ----MTAV--IEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDA----A
                                                         **:.: **** :** *:**:.*:     .

Mb3348|M.bovis_AF2122/97            GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
Rv3319|M.tuberculosis_H37Rv         GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
MAV_4300|M.avium_104                GWQSFRVPCLPSDRMLNLLIYIKSYLDGTLTFRRSCAHGVCGSDAMRING
MLBr_00696|M.leprae_Br4923          GWQSFRVPCLPTDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRVNG
MMAR_1200|M.marinum_M               GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
MUL_1370|M.ulcerans_Agy99           GWQSFRVPCLPSDRLLNLLIYIKGYLDGTLTFRRSCAHGVCGSDAMRING
Mflv_4847|M.gilvum_PYR-GCK          GWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRING
Mvan_1586|M.vanbaalenii_PYR-1       GWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRING
MSMEG_1669|M.smegmatis_MC2_155      GWQSFRVPCLPSDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRING
TH_2183|M.thermoresistible__bu      GFQSFRVPTLPTDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGSDAMRVNG
MAB_3676|M.abscessus_ATCC_1997      GWQTFRVPCLPTDRLLNLLLYVKGYLDGTLTFRRSCAHGVCGSDAMRING
                                    *:*:**** **:**:**** *:* ***********************:**

Mb3348|M.bovis_AF2122/97            VNRLACKVLMRDLLPKKK----GKSLTVTVEPIRGLPVEKDLVVDMEPFF
Rv3319|M.tuberculosis_H37Rv         VNRLACKVLMRDLLPKKK----GKSLTVTVEPIRGLPVEKDLVVDMEPFF
MAV_4300|M.avium_104                VNRLACKVLMRDLLPEPKKGKPGKPLTITVEPIRGLPVEKDLVVDMEPFF
MLBr_00696|M.leprae_Br4923          VNRLACKVLMRDLLPKKA----GKNLTITVEPIRGLPVEKDLVVDMEPFF
MMAR_1200|M.marinum_M               VNRLACKVLMRDLLPKKP----GKQLTLTVEPIRGLPVEKDLVVDMEPFF
MUL_1370|M.ulcerans_Agy99           VNRLACKVLMRDLLPKKS----GKQLTLTVEPIRGLPVEKDLVVDMEPFF
Mflv_4847|M.gilvum_PYR-GCK          VNRLACKVLMRDMLPKNP----NKQLTITIEPIRGLPVEKDLVVDMEPFF
Mvan_1586|M.vanbaalenii_PYR-1       VNRLACKVLMRDMLPKNP----KKQLTITIEPIRGLPVEKDLVVDMEPFF
MSMEG_1669|M.smegmatis_MC2_155      VNRLACKVLMRDMLPKNP----NKQLTITIEPIRGLPVEKDLVVNMEPFF
TH_2183|M.thermoresistible__bu      VNRLACKVLMRDLLPKNP----KKELTVTVEPIRGLPVEKDLVVDMEPFF
MAB_3676|M.abscessus_ATCC_1997      VNRLACKVLMRDLLPKNP----KKTLTITIEPIRGLPVEKDLVVNMEPFF
                                    ************:**:       * **:*:**************:*****

Mb3348|M.bovis_AF2122/97            DAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
Rv3319|M.tuberculosis_H37Rv         DAYRAIKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
MAV_4300|M.avium_104                DAYRAVKPYLITTGNPPTRERIQSPADRARYDDTTKCILCAACTTSCPIF
MLBr_00696|M.leprae_Br4923          DAYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
MMAR_1200|M.marinum_M               DAYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
MUL_1370|M.ulcerans_Agy99           DAYRAVKPYLITSGNPPTRERIQSPTDRARYDDTTKCILCACCTTSCPVF
Mflv_4847|M.gilvum_PYR-GCK          DAFRAVKPYLITSGNQPTRERIQSQTDRARYDDTTKCILCACCTTSCPVY
Mvan_1586|M.vanbaalenii_PYR-1       DAFRAIKPYLITSGNQPTRERIQSQTDRARYDDTTKCILCACCTTSCPVY
MSMEG_1669|M.smegmatis_MC2_155      DAYRAVKPFLVTSGNPPTKERIQSPTDRARYDDTTKCILCACCTTSCPVY
TH_2183|M.thermoresistible__bu      DAYRAVKPFLVTSGNPPTRERLQSPQDRARYDDTTKCILCACCTTSCPVY
MAB_3676|M.abscessus_ATCC_1997      DAYRAVKPFMITSGNQPTREYIQSQTDRARFDDTTKCILCACCTTSCPVF
                                    **:**:**:::*:** **:* :**  ****:**********.******::

Mb3348|M.bovis_AF2122/97            WHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
Rv3319|M.tuberculosis_H37Rv         WHEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
MAV_4300|M.avium_104                WHEGSYYGPAAIVNAHRFIFDSRDEGAAERLDILNEVDGVWRCRTTFNCT
MLBr_00696|M.leprae_Br4923          WSEGTYYGPAAIVNAHRFIFDSRDEGAGERLTLLNEVDGVWRCRTTFNCT
MMAR_1200|M.marinum_M               WNEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
MUL_1370|M.ulcerans_Agy99           WNEGSYLGPAAIVNAHRFIFDSRDEAAAERVDILNEVDGVWRCRTTFNCT
Mflv_4847|M.gilvum_PYR-GCK          WSEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDIDGVWRCRTTFNCT
Mvan_1586|M.vanbaalenii_PYR-1       WNEGSYFGPAAIVNAHRFIFDSRDEGAAERLDILNDVDGVWRCRTTFNCT
MSMEG_1669|M.smegmatis_MC2_155      WSEGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNEVDGVWRCRTTFNCT
TH_2183|M.thermoresistible__bu      WTEGSYFGPAAIVNAHRFIFDSRDEAAGERLDILNEVDGVWRCRTTFNCT
MAB_3676|M.abscessus_ATCC_1997      WSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCT
                                    * :*:* ******************.*.**: :**::*************

Mb3348|M.bovis_AF2122/97            ESCPRGIEVTKAIQEVKRALMFTR
Rv3319|M.tuberculosis_H37Rv         ESCPRGIEVTKAIQEVKRALMFTR
MAV_4300|M.avium_104                DACPRGIEVTKAIQEVKRAIMFSR
MLBr_00696|M.leprae_Br4923          ESCPRNIEVTKAIQEVKRALMFSR
MMAR_1200|M.marinum_M               EACPRGIEVTKAIQEVKRALLFSR
MUL_1370|M.ulcerans_Agy99           EACPRGIEATKAIQEVKRALLFSR
Mflv_4847|M.gilvum_PYR-GCK          EACPRGIQVTKAIQEVKRALMFAR
Mvan_1586|M.vanbaalenii_PYR-1       EACPRGIQVTKAIQEVKRALMFAR
MSMEG_1669|M.smegmatis_MC2_155      EACPRGIQVTQAIQEVKRALMFAR
TH_2183|M.thermoresistible__bu      ESCPRGIQVTKAIQEVKRALMFAR
MAB_3676|M.abscessus_ATCC_1997      DACPRGIEVTKAIQEVKRALMFAR
                                    ::***.*:.*:********::*:*