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VGMADLPFGFSAGDDPDRDKRNKDNSGSGPGSGADPFGLGMPGAGGEFDMSQLGQIFSKLGEMFSGAGTS MSGGTSGGPVNYDLARQLAASSIGFVAPIPEQTTSAIADAVRLAETWLDGVTPIPAGTTRTAAWTPTDWI DNTMSTWKRLCDPVAEQISTVWAQALPQEAQAMAGPLLAMMSQMGGMAFGSQLGQALGTLSKEVLTSTDI GLPLGPKGVAALMPEAVESLAEGLEQPRSEIVTFLAAREAAHHRLFSHVPWLSSQLLNAVEAFAKGTKID MSGIEEFARGFNPASLTDPSEMEQLLNQGIFEPKATPEQTAALERLETMLALIEGWVQTVVTDALGDRIP GTSALSEMLRRRRATGGPAEQTFATLVGLELRPRKMREAADLWVRLTDAVGADARDGVWQHPDLLPSASD LDEPAAFIDRMIGGDTSDIDSAIADLERDFRRGDSGPGESTE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4656 | - | - | 100% (462) | hypothetical protein Mflv_4656 |
| M. gilvum PYR-GCK | Mflv_1410 | - | 8e-13 | 21.43% (280) | hypothetical protein Mflv_1410 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3217 | - | 0.0 | 75.44% (452) | hypothetical protein Mb3217 |
| M. tuberculosis H37Rv | Rv3195 | - | 0.0 | 75.44% (452) | hypothetical protein Rv3195 |
| M. leprae Br4923 | MLBr_00642 | - | 0.0 | 71.62% (458) | hypothetical protein MLBr_00642 |
| M. abscessus ATCC 19977 | MAB_3501 | - | 0.0 | 72.93% (447) | hypothetical protein MAB_3501 |
| M. marinum M | MMAR_1369 | - | 0.0 | 74.68% (462) | hypothetical protein MMAR_1369 |
| M. avium 104 | MAV_4139 | - | 0.0 | 73.25% (456) | hypothetical protein MAV_4139 |
| M. smegmatis MC2 155 | MSMEG_1957 | - | 0.0 | 82.90% (462) | hypothetical protein MSMEG_1957 |
| M. thermoresistible (build 8) | TH_1130 | - | 0.0 | 80.35% (458) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2507 | - | 0.0 | 74.46% (462) | hypothetical protein MUL_2507 |
| M. vanbaalenii PYR-1 | Mvan_1812 | - | 0.0 | 90.83% (458) | hypothetical protein Mvan_1812 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4656|M.gilvum_PYR-GCK -----------MGMADLPFGFSAGDDPDRDKRNKDN---SGSGPG-SGAD
Mvan_1812|M.vanbaalenii_PYR-1 ------MVSTVGGMADLPFGFSAGDDPDRDKRKNDN---PDSGPG-SGGD
MSMEG_1957|M.smegmatis_MC2_155 -------------MADLPFGFSAGDDPDRDKNKKDPD--SGSGSGNPGSD
TH_1130|M.thermoresistible__bu -------------MADLPFGFSPGDDPDRDKGKRDP----GSGSGPSGSD
MMAR_1369|M.marinum_M -------MGTVGVMADLPFGFSSGDDPRDDRSGRDKPGNNDPESGS-DAN
MUL_2507|M.ulcerans_Agy99 -------MGTVGVMADLPFGFSSGDDPRDDRSGRDKPGNNDPESGS-DAN
Mb3217|M.bovis_AF2122/97 -------MSTGEVMGDLPFGFSSGDDPPEDPSGRDKRGKDGADSGS-GAN
Rv3195|M.tuberculosis_H37Rv -------MSTGEVMGDLPFGFSSGDDPPEDPSGRDKRGKDGADSGS-GAN
MLBr_00642|M.leprae_Br4923 MAHSGSPVSTVDGVANPPFGFSSGNDSPNDESGRDKHGKNGPDSGSSGSD
MAV_4139|M.avium_104 -------------MADLPFGFSSGEDP-------DKPGKKDPDSGSNPSD
MAB_3501|M.abscessus_ATCC_1997 -------------MADLPFGFAAGDDPDRERGDAGR---GSSGSGSSGAD
:.: ****:.*:*. . .. .* .:
Mflv_4656|M.gilvum_PYR-GCK PFGLGMPGAGGEFDMSQLGQIFSKLGEMFSGAGTSMSGGTSGGPVNYDLA
Mvan_1812|M.vanbaalenii_PYR-1 PFGSGFP--GGEFDMSQLGQIFSKLGEMFSGAGTSMAGGTSAGPVNYDLA
MSMEG_1957|M.smegmatis_MC2_155 PFGLGMG--GAGFDMGDLGQIFTKLGEMFSGAGSAMAGGKQSGPVNYDLA
TH_1130|M.thermoresistible__bu PF----G--GAGFDLGDLGQIFTRLGEMFSGAGNVMAGGAQSGPVNYDLA
MMAR_1369|M.marinum_M PLG-AFG-IGGDFGMADLGQIFTRLGEMFGGVGSAMTSGQSSGPVNYQLA
MUL_2507|M.ulcerans_Agy99 PLG-AFG-IGGYFGMADLGQIFTRLGEMFGGVGSAMTSGQSSGPVNYQLA
Mb3217|M.bovis_AF2122/97 PLG-AFG-IGGEFNMADLGQIFTRLGEMFGGVGTAMAAGKTSGPVNYDLA
Rv3195|M.tuberculosis_H37Rv PLG-AFG-IGGEFNMADLGQIFTRLGEMFGGVGTAMAAGKTSGPVNYDLA
MLBr_00642|M.leprae_Br4923 PLA-SFG-MSGDFGMSDLGQIFTHLGQMFTNAGTAMTADKQLGPVNYELA
MAV_4139|M.avium_104 PFA-AFG-ISGEFGMGDLGQIFTQLGQMFSSAGSASAGGSDSGPVNYELA
MAB_3501|M.abscessus_ATCC_1997 PFG--FG--SGGFNPADLGQIFTQLGQMFSGAAAGAASGQPAGPVNYDIA
*: .. *. .:*****::**:** ... :.. *****::*
Mflv_4656|M.gilvum_PYR-GCK RQLAASSIGFVAPIPEQTTSAIADAVRLAETWLDGVTPIPAGTTRTAAWT
Mvan_1812|M.vanbaalenii_PYR-1 RQLASSSIGFVAPIPEQTATAISDAVRLAETWLDGVTPLPAGTTRAVAWT
MSMEG_1957|M.smegmatis_MC2_155 RQLANSSIGFVAPVPEKTAGAVADAVRLAETWLDGVTPLPAGTTRTVAWT
TH_1130|M.thermoresistible__bu RQLASSSIGFVAPVPDTTRSAIADAVHLAETWLDGATAIPAGTTRTVAWT
MMAR_1369|M.marinum_M RQVAASSIGFIAPIPDATNSAISDAVHLAETWLNGATSLPAGTAKAVGWS
MUL_2507|M.ulcerans_Agy99 RQVAASSIGFIAPIPDATNSAISDAVHLAETWLDGATSLPAGTAKAVGWS
Mb3217|M.bovis_AF2122/97 RQVASSSIGFIAPIPAATNSAIADAVHLADTWLDGATSLPAGATKAVGWS
Rv3195|M.tuberculosis_H37Rv RQVASSSIGFIAPIPAATNSAIADAVHLADTWLDGATSLPAGATKAVGWS
MLBr_00642|M.leprae_Br4923 RRVASSSIGFVAPIPATTSSAIGDAVHLAETWLDGVTALPAGTTKAEGWT
MAV_4139|M.avium_104 RRVASNSIGFVAPIPATTNSAIADAVHLAETWLDGATALPAGTAKAVGWT
MAB_3501|M.abscessus_ATCC_1997 RQLASSSIGFVAPITASTTSAITDAVHLADTWLDGATSLPAGATRTAAWT
*::* .****:**:. * *: ***:**:***:*.*.:***:::: .*:
Mflv_4656|M.gilvum_PYR-GCK PTDWIDNTMSTWKRLCDPVAEQISTVWAQALPQEAQAMAGPLLAMMSQMG
Mvan_1812|M.vanbaalenii_PYR-1 PTDWIDNTMDTWKRLCDPVAQQISTVWAQALPEEAKAMAGPLLAMMSQMG
MSMEG_1957|M.smegmatis_MC2_155 PSDWLDNTMETWKRLCDPVAEQVSTMWTAALPEEAKAMAGPLLAMMSQMG
TH_1130|M.thermoresistible__bu PTDWIDNTLDTWKRLCDPVAEQVSAVWTAALPEEARAMAGPLLAMMTQMG
MMAR_1369|M.marinum_M PTDWVDNTMDVWKRLCDPMAQQISSVWASSLPEEAKSMAGPLLSMMSQMG
MUL_2507|M.ulcerans_Agy99 PTDWVDNTMDVWKRLCDPMAQQISSVWASSLPEEAKSMAGPLLSMMSQMR
Mb3217|M.bovis_AF2122/97 PTDWVDNTLATWKRLCDPMAQQISTVWASSLPEEAKSMAGPLLSIMSQMG
Rv3195|M.tuberculosis_H37Rv PTDWVDNTLATWKRLCDPMAQQISTVWASSLPEEAKSMAGPLLSIMSQMG
MLBr_00642|M.leprae_Br4923 PDDWVNNTLETWKRLCDPMAQQISTVWAASLPEEAKSMASPLLSMMSQMG
MAV_4139|M.avium_104 PADWVDNTLGTWKRLCDPMAQQISTVWAASLPEEAKSMAGPLLQMMSQMG
MAB_3501|M.abscessus_ATCC_1997 ATDWVDNTLENWKRLVDPVAEQISGMWAANLPEEAQSMAGPLLGMMTQMG
. **::**: **** **:*:*:* :*: **:**::**.*** :*:**
Mflv_4656|M.gilvum_PYR-GCK GMAFGSQLGQALGTLSKEVLTSTDIGLPLGPKGVAALMPEAVESLAEGLE
Mvan_1812|M.vanbaalenii_PYR-1 GMAFGSQLGQALGTLSKEVLTSTDIGLPLGPKGIAALMPEAIEALAEGLE
MSMEG_1957|M.smegmatis_MC2_155 GMAFGSQLGQALGKLSREVLTSTDIGLPLGPKGVAALLPEAIEAFAEGLE
TH_1130|M.thermoresistible__bu GMAFGSQLGQALGKLSREVLTSTDIGLPLGPKGVAALLPSNIETFSEGLE
MMAR_1369|M.marinum_M GMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPEAVESFASGLE
MUL_2507|M.ulcerans_Agy99 GMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPEAVESFASGLE
Mb3217|M.bovis_AF2122/97 GIAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPGAVESFAAGLE
Rv3195|M.tuberculosis_H37Rv GIAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPGAVESFAAGLE
MLBr_00642|M.leprae_Br4923 GMAFGSQLGQAFGQLSREVLTSTDIGLPLGPRGVAAIMPQAVESFADGLE
MAV_4139|M.avium_104 GMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGIAAILPDAVESFASGLE
MAB_3501|M.abscessus_ATCC_1997 GMAFGSQLGQALGQLSREVLTSTDIGLPLGPKGTAALMPAAIETFSEGLE
*:*********:* **:**************:* **::* :*::: ***
Mflv_4656|M.gilvum_PYR-GCK QPRSEIVTFLAAREAAHHRLFSHVPWLSSQLLNAVEAFAKGTKIDMSGIE
Mvan_1812|M.vanbaalenii_PYR-1 QPRSEIVTFLAAREAAHHRLFSHVPWLPGQLLNAVEAFARGTKIDMSGIE
MSMEG_1957|M.smegmatis_MC2_155 RPRSEILTFLAAREAAHHRLFSHVPWLSSQLLGAVEAFAKGMKVDMSGIE
TH_1130|M.thermoresistible__bu HPRSEVLTFLAAREAAHHRLFSHVPWLSSQLLNAVEAFARGIKIDMTGIE
MMAR_1369|M.marinum_M QPRSEIMTFLAAREAAHHRLFSHVPWLSSQLLGAVEAYAAGMKIDMSGIE
MUL_2507|M.ulcerans_Agy99 RPRSEIMTFLAAREAAHHRLFSHVPWLSSQLLGAVEAYAAGMKIDMSGIE
Mb3217|M.bovis_AF2122/97 QPRSEILTFLATREAAHHRLFSHVPWLASQLLGAVEAYAMGMKIDMTGIE
Rv3195|M.tuberculosis_H37Rv QPRSEILTFLATREAAHHRLFSHVPWLASQLLGAVEAYAMGMKIDMTGIE
MLBr_00642|M.leprae_Br4923 QPRCEILTFLATREAAHHRLFSHVPWLASQLLGAVEAYAAGMKIDMNGIE
MAV_4139|M.avium_104 RPRSEILTFLAAREAAHHRLFSHVPWLASQLLGAVEAYAMGMQIDMSGIE
MAB_3501|M.abscessus_ATCC_1997 QSKGEIMTFLAAREAAHHRLFSGVGWLTIRLMDTVEQYAKGISIDMSAIE
:.: *::****:********** * **. :*:.:** :* * .:**..**
Mflv_4656|M.gilvum_PYR-GCK EFARGFNPASLTDPSEMEQLLNQGIFEPKATPEQTAALERLETMLALIEG
Mvan_1812|M.vanbaalenii_PYR-1 EFARGFNPASLTDPSEMEQLLNQGIFEPKATPEQTAALERLETTLALIEG
MSMEG_1957|M.smegmatis_MC2_155 DFARGFNPASLSDPSEMEQLLNQGIFEPKATPEQEAALERLETLLALVEG
TH_1130|M.thermoresistible__bu ELAAGFSPTSLNDPSAMEELLNQGIFEPKSTPEQEAALERLETLLALIEG
MMAR_1369|M.marinum_M ELARDFNPATLGDPAAMEQLLSQGVFEPQATPAQTQALERLETLLALIEG
MUL_2507|M.ulcerans_Agy99 ELARDFNPATLGDPAAMEQLLSQGVFEPQATPAQTQALERLETLLALIEG
Mb3217|M.bovis_AF2122/97 ELARDINPTSLADPAAMEQLLSQGVFEPKATPAQTQALERLETLLALIEG
Rv3195|M.tuberculosis_H37Rv ELARDINPTSLADPAAMEQLLSQGVFEPKATPAQTQALERLETLLALIEG
MLBr_00642|M.leprae_Br4923 ELARDFNPASLSDPTAIEELLGQGVFEPQATPAQTQALERLEALLALIEG
MAV_4139|M.avium_104 ELARDFNPASLSDPAAIENLLGQGVFEPKATPAQTQALERLETLLALIEG
MAB_3501|M.abscessus_ATCC_1997 EAARGFNPAAMGDPSEMEQILSQGIFEPKTTPQQEQALERLETLLALVEG
: * .:.*::: **: :*::*.**:***::** * ******: ***:**
Mflv_4656|M.gilvum_PYR-GCK WVQTVVTDALGDRIPGTSALSEMLRRRRATGGPAEQTFATLVGLELRPRK
Mvan_1812|M.vanbaalenii_PYR-1 WVQTVVSDALGDRIPGTPALSEMLRRRRATGGPAEQTFATLVGLELRPRK
MSMEG_1957|M.smegmatis_MC2_155 WVQTVVSGALGERIPGTSAMAETMRRRRATGGPAEQTFATLVGLELRPRK
TH_1130|M.thermoresistible__bu WVQTVVTAALGDRIPATSALSELLRRRRATGGPAEQTFATLVGLELRPRK
MMAR_1369|M.marinum_M WVQTVVTDALGDRIPGTAALSETLRRRRASGGPAEQTFTTLVGLELRPRK
MUL_2507|M.ulcerans_Agy99 WVQTVVTDALGDRIPGTAALSETLRRRRASGGPAEQTFTTLVGLELRPRK
Mb3217|M.bovis_AF2122/97 WVQTVVTAALGERIPGEAALSETLRRRRASGGPAEQTFATLVGLELRPRK
Rv3195|M.tuberculosis_H37Rv WVQTVVTAALGERIPGEAALSETLRRRRASGGPAEQTFATLVGLELRPRK
MLBr_00642|M.leprae_Br4923 WVQVVVTAALGDRIPGAAALGETLRRRRASGGPAEQTFATLVGLELRPRK
MAV_4139|M.avium_104 WVQVVVAAALGDRIPGAAALAETLRRRRASGGPAEQTFATLVGLELRPRK
MAB_3501|M.abscessus_ATCC_1997 WVQTVVTDALGERIPATAALSETLRRRRATGGPAEQTFATLVGLELRPRK
***.**: ***:***. .*:.* :*****:********:***********
Mflv_4656|M.gilvum_PYR-GCK MREAADLWVRLTDAVGADARDGVWQHPDLLPSASDLDEPAAFIDRMIGGD
Mvan_1812|M.vanbaalenii_PYR-1 MREAADLWRKLTEAVGADTRDSVWQHPDLLPSAGDLDEPAAFIDRMIGGD
MSMEG_1957|M.smegmatis_MC2_155 MREAAVLWERLTEAVGADARDSVWQHPDLLPSASDLDEPAGFIDRMIGGD
TH_1130|M.thermoresistible__bu MREAAALWERLTEAVGADARDGVWQHPDLLPDAADLDEPAGFIDRMIGGD
MMAR_1369|M.marinum_M LREAAALWDRLTQGAGIDARDAVWQHPDLLPSIEDLDDPAAFIDRTIGGD
MUL_2507|M.ulcerans_Agy99 LREAAALWDRLTQGAGIDARDAVWQHPDLLPSIEDLDDPAAFIDRTIGGD
Mb3217|M.bovis_AF2122/97 LREAGALWERLTRAVGMDARDAVWQHPDLLPATDDLDDPAAFIDRVIGGD
Rv3195|M.tuberculosis_H37Rv LREAGALWERLTRAVGMDARDAVWQHPDLLPATDDLDDPAAFIDRVIGGD
MLBr_00642|M.leprae_Br4923 LREAAVLWERLTQAAGVDARDAVWQHPDLLPSGKDLDDPASFIDRIIGGD
MAV_4139|M.avium_104 MREAAALWERLTEAAGVDARDGIWQHPDLLPDADDLDDPAAFIDRVIGGD
MAB_3501|M.abscessus_ATCC_1997 LREAADLWRRLTDAVGVDKRDAVWAHPDLMPDASDLDNPAAFIDRIIGGD
:***. ** :** ..* * **.:* ****:* ***:**.**** ****
Mflv_4656|M.gilvum_PYR-GCK TSDIDS----AIADLERDFRRGD-----SGPGESTE-
Mvan_1812|M.vanbaalenii_PYR-1 TSDLDN----AIADLERDLRRGD-----AGPDEPRD-
MSMEG_1957|M.smegmatis_MC2_155 TSGIDDAIDQAIADLQKNDPPQEGDSGTEGAGDDKS-
TH_1130|M.thermoresistible__bu TSGID----EALADLGKETDPE------KAPGEDDTD
MMAR_1369|M.marinum_M TSGIDE----ALSDLKAELDRDMRNREDPGSGPVDN-
MUL_2507|M.ulcerans_Agy99 TSGIDE----ALSDLKAELDRDMRNREDPGAGPVDN-
Mb3217|M.bovis_AF2122/97 TSGIDE----AIAELERDQQARGADDSGHDGGPVDN-
Rv3195|M.tuberculosis_H37Rv TSGIDE----AIAELERDQQARGADDSGHDGGPVDN-
MLBr_00642|M.leprae_Br4923 TSGIDE----AIAKLDLD-RGNSDGRTPGSGGPVDN-
MAV_4139|M.avium_104 TSGIDE----AIARLEQE-GPDS----PGSGGGDT--
MAB_3501|M.abscessus_ATCC_1997 TDAVDD----PIAQIQKLDPGTP---------PTED-
*. :* .:: :