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M. thermoresistible (build 8) TH_1130 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2196365 - 2197729
length: 455

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1130-100% (455)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1411-5e-1221.38% (304) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3217-0.073.32% (461) hypothetical protein Mb3217
M. gilvum PYR-GCKMflv_4656-0.080.35% (458) hypothetical protein Mflv_4656
M. tuberculosis H37RvRv3195-0.073.32% (461) hypothetical protein Rv3195
M. leprae Br4923MLBr_00642-0.070.81% (459) hypothetical protein MLBr_00642
M. abscessus ATCC 19977MAB_3501-0.072.47% (454) hypothetical protein MAB_3501
M. marinum MMMAR_1369-0.073.36% (458) hypothetical protein MMAR_1369
M. avium 104MAV_4139-0.075.49% (457) hypothetical protein MAV_4139
M. smegmatis MC2 155MSMEG_1957-0.081.68% (464) hypothetical protein MSMEG_1957
M. ulcerans Agy99MUL_2507-0.073.36% (458) hypothetical protein MUL_2507
M. vanbaalenii PYR-1Mvan_1812-0.080.04% (446) hypothetical protein Mvan_1812

CLUSTAL 2.0.9 multiple sequence alignment


TH_1130|M.thermoresistible__bu      -------------MADLPFGFSPGDDPDRDKGKRDP----GSGSGPSGSD
MSMEG_1957|M.smegmatis_MC2_155      -------------MADLPFGFSAGDDPDRDKNKKDPD--SGSGSGNPGSD
Mflv_4656|M.gilvum_PYR-GCK          -----------MGMADLPFGFSAGDDPDRDKRNKDN---SGSGPG-SGAD
Mvan_1812|M.vanbaalenii_PYR-1       ------MVSTVGGMADLPFGFSAGDDPDRDKRKNDN---PDSGPG-SGGD
MMAR_1369|M.marinum_M               -------MGTVGVMADLPFGFSSGDDPRDDRSGRDKPGNNDPESGS-DAN
MUL_2507|M.ulcerans_Agy99           -------MGTVGVMADLPFGFSSGDDPRDDRSGRDKPGNNDPESGS-DAN
Mb3217|M.bovis_AF2122/97            -------MSTGEVMGDLPFGFSSGDDPPEDPSGRDKRGKDGADSGS-GAN
Rv3195|M.tuberculosis_H37Rv         -------MSTGEVMGDLPFGFSSGDDPPEDPSGRDKRGKDGADSGS-GAN
MLBr_00642|M.leprae_Br4923          MAHSGSPVSTVDGVANPPFGFSSGNDSPNDESGRDKHGKNGPDSGSSGSD
MAV_4139|M.avium_104                -------------MADLPFGFSSGEDP-------DKPGKKDPDSGSNPSD
MAB_3501|M.abscessus_ATCC_1997      -------------MADLPFGFAAGDDPDRERGDAGR---GSSGSGSSGAD
                                                 :.: ****:.*:*.       .     .. .*   .:

TH_1130|M.thermoresistible__bu      PF------GGAGFDLGDLGQIFTRLGEMFSGAGNVMAGGAQSGPVNYDLA
MSMEG_1957|M.smegmatis_MC2_155      PFG--LGMGGAGFDMGDLGQIFTKLGEMFSGAGSAMAGGKQSGPVNYDLA
Mflv_4656|M.gilvum_PYR-GCK          PFGLGMPGAGGEFDMSQLGQIFSKLGEMFSGAGTSMSGGTSGGPVNYDLA
Mvan_1812|M.vanbaalenii_PYR-1       PFGSGFP--GGEFDMSQLGQIFSKLGEMFSGAGTSMAGGTSAGPVNYDLA
MMAR_1369|M.marinum_M               PLG--AFGIGGDFGMADLGQIFTRLGEMFGGVGSAMTSGQSSGPVNYQLA
MUL_2507|M.ulcerans_Agy99           PLG--AFGIGGYFGMADLGQIFTRLGEMFGGVGSAMTSGQSSGPVNYQLA
Mb3217|M.bovis_AF2122/97            PLG--AFGIGGEFNMADLGQIFTRLGEMFGGVGTAMAAGKTSGPVNYDLA
Rv3195|M.tuberculosis_H37Rv         PLG--AFGIGGEFNMADLGQIFTRLGEMFGGVGTAMAAGKTSGPVNYDLA
MLBr_00642|M.leprae_Br4923          PLA--SFGMSGDFGMSDLGQIFTHLGQMFTNAGTAMTADKQLGPVNYELA
MAV_4139|M.avium_104                PFA--AFGISGEFGMGDLGQIFTQLGQMFSSAGSASAGGSDSGPVNYELA
MAB_3501|M.abscessus_ATCC_1997      PFG----FGSGGFNPADLGQIFTQLGQMFSGAAAGAASGQPAGPVNYDIA
                                    *:       .. *. .:*****::**:** ...   :..   *****::*

TH_1130|M.thermoresistible__bu      RQLASSSIGFVAPVPDTTRSAIADAVHLAETWLDGATAIPAGTTRTVAWT
MSMEG_1957|M.smegmatis_MC2_155      RQLANSSIGFVAPVPEKTAGAVADAVRLAETWLDGVTPLPAGTTRTVAWT
Mflv_4656|M.gilvum_PYR-GCK          RQLAASSIGFVAPIPEQTTSAIADAVRLAETWLDGVTPIPAGTTRTAAWT
Mvan_1812|M.vanbaalenii_PYR-1       RQLASSSIGFVAPIPEQTATAISDAVRLAETWLDGVTPLPAGTTRAVAWT
MMAR_1369|M.marinum_M               RQVAASSIGFIAPIPDATNSAISDAVHLAETWLNGATSLPAGTAKAVGWS
MUL_2507|M.ulcerans_Agy99           RQVAASSIGFIAPIPDATNSAISDAVHLAETWLDGATSLPAGTAKAVGWS
Mb3217|M.bovis_AF2122/97            RQVASSSIGFIAPIPAATNSAIADAVHLADTWLDGATSLPAGATKAVGWS
Rv3195|M.tuberculosis_H37Rv         RQVASSSIGFIAPIPAATNSAIADAVHLADTWLDGATSLPAGATKAVGWS
MLBr_00642|M.leprae_Br4923          RRVASSSIGFVAPIPATTSSAIGDAVHLAETWLDGVTALPAGTTKAEGWT
MAV_4139|M.avium_104                RRVASNSIGFVAPIPATTNSAIADAVHLAETWLDGATALPAGTAKAVGWT
MAB_3501|M.abscessus_ATCC_1997      RQLASSSIGFVAPITASTTSAITDAVHLADTWLDGATSLPAGATRTAAWT
                                    *::* .****:**:.  *  *: ***:**:***:*.*.:***:::: .*:

TH_1130|M.thermoresistible__bu      PTDWIDNTLDTWKRLCDPVAEQVSAVWTAALPEEARAMAGPLLAMMTQMG
MSMEG_1957|M.smegmatis_MC2_155      PSDWLDNTMETWKRLCDPVAEQVSTMWTAALPEEAKAMAGPLLAMMSQMG
Mflv_4656|M.gilvum_PYR-GCK          PTDWIDNTMSTWKRLCDPVAEQISTVWAQALPQEAQAMAGPLLAMMSQMG
Mvan_1812|M.vanbaalenii_PYR-1       PTDWIDNTMDTWKRLCDPVAQQISTVWAQALPEEAKAMAGPLLAMMSQMG
MMAR_1369|M.marinum_M               PTDWVDNTMDVWKRLCDPMAQQISSVWASSLPEEAKSMAGPLLSMMSQMG
MUL_2507|M.ulcerans_Agy99           PTDWVDNTMDVWKRLCDPMAQQISSVWASSLPEEAKSMAGPLLSMMSQMR
Mb3217|M.bovis_AF2122/97            PTDWVDNTLATWKRLCDPMAQQISTVWASSLPEEAKSMAGPLLSIMSQMG
Rv3195|M.tuberculosis_H37Rv         PTDWVDNTLATWKRLCDPMAQQISTVWASSLPEEAKSMAGPLLSIMSQMG
MLBr_00642|M.leprae_Br4923          PDDWVNNTLETWKRLCDPMAQQISTVWAASLPEEAKSMASPLLSMMSQMG
MAV_4139|M.avium_104                PADWVDNTLGTWKRLCDPMAQQISTVWAASLPEEAKSMAGPLLQMMSQMG
MAB_3501|M.abscessus_ATCC_1997      ATDWVDNTLENWKRLVDPVAEQISGMWAANLPEEAQSMAGPLLGMMTQMG
                                    . **::**:  **** **:*:*:* :*:  **:**::**.*** :*:** 

TH_1130|M.thermoresistible__bu      GMAFGSQLGQALGKLSREVLTSTDIGLPLGPKGVAALLPSNIETFSEGLE
MSMEG_1957|M.smegmatis_MC2_155      GMAFGSQLGQALGKLSREVLTSTDIGLPLGPKGVAALLPEAIEAFAEGLE
Mflv_4656|M.gilvum_PYR-GCK          GMAFGSQLGQALGTLSKEVLTSTDIGLPLGPKGVAALMPEAVESLAEGLE
Mvan_1812|M.vanbaalenii_PYR-1       GMAFGSQLGQALGTLSKEVLTSTDIGLPLGPKGIAALMPEAIEALAEGLE
MMAR_1369|M.marinum_M               GMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPEAVESFASGLE
MUL_2507|M.ulcerans_Agy99           GMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPEAVESFASGLE
Mb3217|M.bovis_AF2122/97            GIAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPGAVESFAAGLE
Rv3195|M.tuberculosis_H37Rv         GIAFGSQLGQALGRLSREVLTSTDIGLPLGPKGVAAILPGAVESFAAGLE
MLBr_00642|M.leprae_Br4923          GMAFGSQLGQAFGQLSREVLTSTDIGLPLGPRGVAAIMPQAVESFADGLE
MAV_4139|M.avium_104                GMAFGSQLGQALGRLSREVLTSTDIGLPLGPKGIAAILPDAVESFASGLE
MAB_3501|M.abscessus_ATCC_1997      GMAFGSQLGQALGQLSREVLTSTDIGLPLGPKGTAALMPAAIETFSEGLE
                                    *:*********:* **:**************:* **::*  :*::: ***

TH_1130|M.thermoresistible__bu      HPRSEVLTFLAAREAAHHRLFSHVPWLSSQLLNAVEAFARGIKIDMTGIE
MSMEG_1957|M.smegmatis_MC2_155      RPRSEILTFLAAREAAHHRLFSHVPWLSSQLLGAVEAFAKGMKVDMSGIE
Mflv_4656|M.gilvum_PYR-GCK          QPRSEIVTFLAAREAAHHRLFSHVPWLSSQLLNAVEAFAKGTKIDMSGIE
Mvan_1812|M.vanbaalenii_PYR-1       QPRSEIVTFLAAREAAHHRLFSHVPWLPGQLLNAVEAFARGTKIDMSGIE
MMAR_1369|M.marinum_M               QPRSEIMTFLAAREAAHHRLFSHVPWLSSQLLGAVEAYAAGMKIDMSGIE
MUL_2507|M.ulcerans_Agy99           RPRSEIMTFLAAREAAHHRLFSHVPWLSSQLLGAVEAYAAGMKIDMSGIE
Mb3217|M.bovis_AF2122/97            QPRSEILTFLATREAAHHRLFSHVPWLASQLLGAVEAYAMGMKIDMTGIE
Rv3195|M.tuberculosis_H37Rv         QPRSEILTFLATREAAHHRLFSHVPWLASQLLGAVEAYAMGMKIDMTGIE
MLBr_00642|M.leprae_Br4923          QPRCEILTFLATREAAHHRLFSHVPWLASQLLGAVEAYAAGMKIDMNGIE
MAV_4139|M.avium_104                RPRSEILTFLAAREAAHHRLFSHVPWLASQLLGAVEAYAMGMQIDMSGIE
MAB_3501|M.abscessus_ATCC_1997      QSKGEIMTFLAAREAAHHRLFSGVGWLTIRLMDTVEQYAKGISIDMSAIE
                                    :.: *::****:********** * **. :*:.:** :* * .:**..**

TH_1130|M.thermoresistible__bu      ELAAGFSPTSLNDPSAMEELLNQGIFEPKSTPEQEAALERLETLLALIEG
MSMEG_1957|M.smegmatis_MC2_155      DFARGFNPASLSDPSEMEQLLNQGIFEPKATPEQEAALERLETLLALVEG
Mflv_4656|M.gilvum_PYR-GCK          EFARGFNPASLTDPSEMEQLLNQGIFEPKATPEQTAALERLETMLALIEG
Mvan_1812|M.vanbaalenii_PYR-1       EFARGFNPASLTDPSEMEQLLNQGIFEPKATPEQTAALERLETTLALIEG
MMAR_1369|M.marinum_M               ELARDFNPATLGDPAAMEQLLSQGVFEPQATPAQTQALERLETLLALIEG
MUL_2507|M.ulcerans_Agy99           ELARDFNPATLGDPAAMEQLLSQGVFEPQATPAQTQALERLETLLALIEG
Mb3217|M.bovis_AF2122/97            ELARDINPTSLADPAAMEQLLSQGVFEPKATPAQTQALERLETLLALIEG
Rv3195|M.tuberculosis_H37Rv         ELARDINPTSLADPAAMEQLLSQGVFEPKATPAQTQALERLETLLALIEG
MLBr_00642|M.leprae_Br4923          ELARDFNPASLSDPTAIEELLGQGVFEPQATPAQTQALERLEALLALIEG
MAV_4139|M.avium_104                ELARDFNPASLSDPAAIENLLGQGVFEPKATPAQTQALERLETLLALIEG
MAB_3501|M.abscessus_ATCC_1997      EAARGFNPAAMGDPSEMEQILSQGIFEPKTTPQQEQALERLETLLALVEG
                                    : * .:.*::: **: :*::*.**:***::** *  ******: ***:**

TH_1130|M.thermoresistible__bu      WVQTVVTAALGDRIPATSALSELLRRRRATGGPAEQTFATLVGLELRPRK
MSMEG_1957|M.smegmatis_MC2_155      WVQTVVSGALGERIPGTSAMAETMRRRRATGGPAEQTFATLVGLELRPRK
Mflv_4656|M.gilvum_PYR-GCK          WVQTVVTDALGDRIPGTSALSEMLRRRRATGGPAEQTFATLVGLELRPRK
Mvan_1812|M.vanbaalenii_PYR-1       WVQTVVSDALGDRIPGTPALSEMLRRRRATGGPAEQTFATLVGLELRPRK
MMAR_1369|M.marinum_M               WVQTVVTDALGDRIPGTAALSETLRRRRASGGPAEQTFTTLVGLELRPRK
MUL_2507|M.ulcerans_Agy99           WVQTVVTDALGDRIPGTAALSETLRRRRASGGPAEQTFTTLVGLELRPRK
Mb3217|M.bovis_AF2122/97            WVQTVVTAALGERIPGEAALSETLRRRRASGGPAEQTFATLVGLELRPRK
Rv3195|M.tuberculosis_H37Rv         WVQTVVTAALGERIPGEAALSETLRRRRASGGPAEQTFATLVGLELRPRK
MLBr_00642|M.leprae_Br4923          WVQVVVTAALGDRIPGAAALGETLRRRRASGGPAEQTFATLVGLELRPRK
MAV_4139|M.avium_104                WVQVVVAAALGDRIPGAAALAETLRRRRASGGPAEQTFATLVGLELRPRK
MAB_3501|M.abscessus_ATCC_1997      WVQTVVTDALGERIPATAALSETLRRRRATGGPAEQTFATLVGLELRPRK
                                    ***.**: ***:***. .*:.* :*****:********:***********

TH_1130|M.thermoresistible__bu      MREAAALWERLTEAVGADARDGVWQHPDLLPDAADLDEPAGFIDRMIGGD
MSMEG_1957|M.smegmatis_MC2_155      MREAAVLWERLTEAVGADARDSVWQHPDLLPSASDLDEPAGFIDRMIGGD
Mflv_4656|M.gilvum_PYR-GCK          MREAADLWVRLTDAVGADARDGVWQHPDLLPSASDLDEPAAFIDRMIGGD
Mvan_1812|M.vanbaalenii_PYR-1       MREAADLWRKLTEAVGADTRDSVWQHPDLLPSAGDLDEPAAFIDRMIGGD
MMAR_1369|M.marinum_M               LREAAALWDRLTQGAGIDARDAVWQHPDLLPSIEDLDDPAAFIDRTIGGD
MUL_2507|M.ulcerans_Agy99           LREAAALWDRLTQGAGIDARDAVWQHPDLLPSIEDLDDPAAFIDRTIGGD
Mb3217|M.bovis_AF2122/97            LREAGALWERLTRAVGMDARDAVWQHPDLLPATDDLDDPAAFIDRVIGGD
Rv3195|M.tuberculosis_H37Rv         LREAGALWERLTRAVGMDARDAVWQHPDLLPATDDLDDPAAFIDRVIGGD
MLBr_00642|M.leprae_Br4923          LREAAVLWERLTQAAGVDARDAVWQHPDLLPSGKDLDDPASFIDRIIGGD
MAV_4139|M.avium_104                MREAAALWERLTEAAGVDARDGIWQHPDLLPDADDLDDPAAFIDRVIGGD
MAB_3501|M.abscessus_ATCC_1997      LREAADLWRRLTDAVGVDKRDAVWAHPDLMPDASDLDNPAAFIDRIIGGD
                                    :***. ** :** ..* * **.:* ****:*   ***:**.**** ****

TH_1130|M.thermoresistible__bu      TSGID----EALADLGKETDPEK------APGEDDTD
MSMEG_1957|M.smegmatis_MC2_155      TSGIDDAIDQAIADLQKNDPPQEGDSGTEGAGDDKS-
Mflv_4656|M.gilvum_PYR-GCK          TSDID----SAIADLERDFRRGDS-----GPGESTE-
Mvan_1812|M.vanbaalenii_PYR-1       TSDLD----NAIADLERDLRRGDA-----GPDEPRD-
MMAR_1369|M.marinum_M               TSGID----EALSDLKAELDRDMRNREDPGSGPVDN-
MUL_2507|M.ulcerans_Agy99           TSGID----EALSDLKAELDRDMRNREDPGAGPVDN-
Mb3217|M.bovis_AF2122/97            TSGID----EAIAELERDQQARGADDSGHDGGPVDN-
Rv3195|M.tuberculosis_H37Rv         TSGID----EAIAELERDQQARGADDSGHDGGPVDN-
MLBr_00642|M.leprae_Br4923          TSGID----EAIAKLDLD-RGNSDGRTPGSGGPVDN-
MAV_4139|M.avium_104                TSGID----EAIARLEQE-GPDS----PGSGGGDT--
MAB_3501|M.abscessus_ATCC_1997      TDAVD----DPIAQIQKLDPGTP---------PTED-
                                    *. :*    ..:: :