For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_4602 (-)

annotation: TetR family transcriptional regulator
coordinates: 4897202 - 4897861
length: 219

VDTTAVRRAASRLPGRELRREQIIEAALSAIEENGPHALTGQIADKAGLGRTHFYRHFASKEELDLAVAR
HVHRELTAKIRLTLDVQGSPLDVIRAPVTQHVMWADEHPNLYRFLVNRHYRRSTEKTAPGSSAFASELAV
AGARYFPRYGEDSEAADRNVAAIMGLMDASVLWWLDHRDSTRDELVIRLTRQTWLIINDRLQELGFQLDP
HLPLCEPKT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4602--100% (219)TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4290-9e-1931.31% (214) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0103-9e-1123.23% (198) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3076c-8e-1729.19% (209) AsnC family transcriptional regulator
M. tuberculosis H37RvRv3050c-8e-1729.19% (209) AsnC family transcriptional regulator
M. leprae Br4923MLBr_01733-9e-1626.32% (209) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4546c-3e-2333.33% (216) TetR family transcriptional regulator
M. marinum MMMAR_1643-6e-1628.23% (209) AsnC family transcriptional regulator
M. avium 104MAV_3917-5e-1426.32% (209) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_2309-9e-2031.90% (210) transcriptional regulatory protein
M. thermoresistible (build 8)TH_1826-7e-1930.62% (209) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_1879-5e-1628.23% (209) AsnC family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2056-4e-1629.38% (211) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1643|M.marinum_M               -----------------------------MRRISRPHPNADAGVKVDARS
MUL_1879|M.ulcerans_Agy99           -----------------------------MRRISRAHLNADAGVKVDARS
Mb3076c|M.bovis_AF2122/97           -----------------------------MVRIPRPHPSAKPGVKVDARS
Rv3050c|M.tuberculosis_H37Rv        -----------------------------MVRIPRPHPSAKPGVKVDARS
MLBr_01733|M.leprae_Br4923          MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAV_3917|M.avium_104                --------------------------MVRMPRPARPHSATKPGAKVDARS
MSMEG_2309|M.smegmatis_MC2_155      -----------------------------MRRGSRSHSGG-PGVKVDARS
Mvan_2056|M.vanbaalenii_PYR-1       ----------------------MAGYSDRVRRGSRARAAEEPGVKVDARS
TH_1826|M.thermoresistible__bu      ---------------------------------------------VDARS
Mflv_4602|M.gilvum_PYR-GCK          -----------------------------------------MDTTAVRRA
MAB_4546c|M.abscessus_ATCC_199      ---------------------------------------MQPGVQECAAG
                                                                                     .

MMAR_1643|M.marinum_M               ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
MUL_1879|M.ulcerans_Agy99           ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
Mb3076c|M.bovis_AF2122/97           ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
Rv3050c|M.tuberculosis_H37Rv        ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
MLBr_01733|M.leprae_Br4923          ERWREHRKKVRGEIVDAAFRALDRLGPEVSVREIAEEAGTAKPKIYRHFT
MAV_3917|M.avium_104                ERWREHRKKVRNEIVDAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFH
MSMEG_2309|M.smegmatis_MC2_155      ERWREHRKKVRSEIVDAAFRAIDRLGPELSLREIAEEAGTAKPKIYRHFT
Mvan_2056|M.vanbaalenii_PYR-1       ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
TH_1826|M.thermoresistible__bu      ERWREHRKKVRAEIVDAAYRAIDRLGPELSLREIAAEAGTAKPKIYRHFT
Mflv_4602|M.gilvum_PYR-GCK          ASRLPGRELRREQIIEAALSAIEENGPHALTGQIADKAGLGRTHFYRHFA
MAB_4546c|M.abscessus_ATCC_199      -RWSGQRERRRAEFVDAALAAIAEHGPQTSTEQIAVHLGVTRTKLYRHFT
                                          *:  * ::::**  *: . **.    :** . *  :.::**** 

MMAR_1643|M.marinum_M               DKSDLFVAIGERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
MUL_1879|M.ulcerans_Agy99           DKSDLFVAIRERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
Mb3076c|M.bovis_AF2122/97           DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
Rv3050c|M.tuberculosis_H37Rv        DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
MLBr_01733|M.leprae_Br4923          DKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDKH
MAV_3917|M.avium_104                DKSDLFQAIGERLRDMLWTAIFPSIDLKTDSAREVIRRSVEEYVTLVDKH
MSMEG_2309|M.smegmatis_MC2_155      DKSDLFQAIGERLRDMLWSAIFPSINLASDPAREVIRRSVEQYVRLVDEH
Mvan_2056|M.vanbaalenii_PYR-1       DKSDLFQAIGQRMRDMLWAAIFPSINISTDAARTVVFRAVEQYVRLVDEH
TH_1826|M.thermoresistible__bu      DKADLHQAIGQRLRDMLWAAIFPSIDLSADSGREIIRRSVEQYVRLVDQH
Mflv_4602|M.gilvum_PYR-GCK          SKEELDLAVARHVHRELTAKIRLTLDVQG-SPLDVIRAPVTQHVMWADEH
MAB_4546c|M.abscessus_ATCC_199      DAADLQRAVAQRASDMLIADLAPLWEPDG-SMAQIIEAGVGAHARFLVGH
                                    .  :*  *:  :    * : :    :    .   ::   *  :.     *

MMAR_1643|M.marinum_M               PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
MUL_1879|M.ulcerans_Agy99           PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
Mb3076c|M.bovis_AF2122/97           PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
Rv3050c|M.tuberculosis_H37Rv        PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
MLBr_01733|M.leprae_Br4923          PNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRAA
MAV_3917|M.avium_104                PNVLRVFIQGRSTGTPQSTVTILNEGREITLAMADLFDNELREMELDHAA
MSMEG_2309|M.smegmatis_MC2_155      PNVLRFLIQGRFAEQSESTMRALNEGRGITLAMADMFSHELREMELDGAA
Mvan_2056|M.vanbaalenii_PYR-1       PNVVRFLMQGRFAEQSESAMRALNEGRDITLGIAEMFNNELSDMELDNAA
TH_1826|M.thermoresistible__bu      PNVLRFLLQGRFADQSASAARALNEGRDITLAMADMFDNELREIELDPTA
Mflv_4602|M.gilvum_PYR-GCK          PNLYRFLVNRHYRRSTEKTAPGSS---AFASELAVAGARYFPRYGEDSEA
MAB_4546c|M.abscessus_ATCC_199      RNLYRYLAHCSMAENSDGPDAITDIKLAVGTHLGQVFALYLGAFG-AGVE
                                     *: * : :      .  .    .    .   :.      :         

MMAR_1643|M.marinum_M               FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
MUL_1879|M.ulcerans_Agy99           FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
Mb3076c|M.bovis_AF2122/97           LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
Rv3050c|M.tuberculosis_H37Rv        LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
MLBr_01733|M.leprae_Br4923          SELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVGT
MAV_3917|M.avium_104                VELAAHAAFGSAASATEWWLGPEPDSPRLMSRAQFVAHLSTIMMAVIIGT
MSMEG_2309|M.smegmatis_MC2_155      IELAAFATFGAAASATDWWLGSKEDSPRRMPADEFVNHLTTIMVGSINGT
Mvan_2056|M.vanbaalenii_PYR-1       FELAGFATFGAAASATDWWLGAEQDSPRRLPSEKFVDYLTTIMVGSINGT
TH_1826|M.thermoresistible__bu      LELAAHAAFGSIASATDWWLGAETDSPRRMPSDQFIAHLTTITVGAINGT
Mflv_4602|M.gilvum_PYR-GCK          ADRNVAAIMGLMDASVLWWLDHR-DSTR----DELVIRLTRQTWLIINDR
MAB_4546c|M.abscessus_ATCC_199      SDILAMGIVGMVETATSHWLDNPGTTSQ----ERLIADQVRWIWLLLDDT
                                     :    . .*   ::.  **.    :.:     .::          : . 

MMAR_1643|M.marinum_M               AEALGIAMDPDKPIHDAVPAPTADRR--------
MUL_1879|M.ulcerans_Agy99           AEALGIAMDPDKPIHDAVPAPTADRR--------
Mb3076c|M.bovis_AF2122/97           AEALGIAVDPDQPIHDAVPNNPAVR---------
Rv3050c|M.tuberculosis_H37Rv        AEALGIAVDPDQPIHDAVPNNPAVR---------
MLBr_01733|M.leprae_Br4923          AETLGISMNPDRPIHDAVPLDRSAS---------
MAV_3917|M.avium_104                AETLGITMNPDQPIHDAVVRKPAVS---------
MSMEG_2309|M.smegmatis_MC2_155      CELLGIRIDPDLPLHEGVQRRERAS---------
Mvan_2056|M.vanbaalenii_PYR-1       CEVLGIKIDPDVPLHEGVKRREQVA---------
TH_1826|M.thermoresistible__bu      CEMLGIKIDPDLPLHAGVRRREDVA---------
Mflv_4602|M.gilvum_PYR-GCK          LQELGFQLDPHLPLCEPKT---------------
MAB_4546c|M.abscessus_ATCC_199      LRAEGIYVNPNEPLPPPDEIARTADSYRDPSRLR
                                     .  *: ::*. *: