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MRAIQIAELSGPGAARLVEIDEPAADDGTVLVEVHAAGVAFPDALQSRGLYQYKPEMPYTPGAEVAGVVR SAPAGAHVKAGDRVAGLTMLCGAMAEVVALQPERVFALPDSVSFEAGAGILFNDLTVQFALRTRGRLAAG ETVLVHGAAGGIGTSTLRLAPAFGASRTIAVVSTEEKADVARAAGATDVVLADGFKDAVKELTGGRGVDI VVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGDIPTVKVNRLLLNNVDAVGVGWGAWTMTHPGYLQEQWAE LEPLLASGTVPAPEPVVYPLERAAEAIASLEDRSARGKVVVAVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4503 | - | - | 100% (324) | alcohol dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0740 | - | 3e-72 | 49.07% (324) | alcohol dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2449 | - | 8e-41 | 35.35% (331) | alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3165 | fadB4 | 1e-136 | 73.15% (324) | NADPH quinone oxidoreductase |
| M. tuberculosis H37Rv | Rv3141 | fadB4 | 1e-136 | 73.15% (324) | NADPH quinone oxidoreductase |
| M. leprae Br4923 | MLBr_00118 | - | 2e-27 | 29.81% (312) | putative oxidireductase |
| M. abscessus ATCC 19977 | MAB_4603c | - | 2e-72 | 46.27% (322) | oxidoreductase |
| M. marinum M | MMAR_1498 | fadB4 | 1e-138 | 74.69% (324) | NADPH quinone oxidoreductase FadB4 |
| M. avium 104 | MAV_4021 | - | 1e-140 | 76.54% (324) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_2033 | - | 1e-143 | 77.78% (324) | oxidoreductase, zinc-binding dehydrogenase family protein |
| M. thermoresistible (build 8) | TH_3116 | - | 1e-149 | 81.93% (321) | PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein |
| M. ulcerans Agy99 | MUL_2439 | fadB4 | 1e-138 | 74.69% (324) | NADPH quinone oxidoreductase FadB4 |
| M. vanbaalenii PYR-1 | Mvan_1864 | - | 1e-167 | 91.67% (324) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3165|M.bovis_AF2122/97 MRAVRVTRLEGPDAVEVAEVEEPT--SAGVVIEVHAAGVAFPDALLTRGR
Rv3141|M.tuberculosis_H37Rv MRAVRVTRLEGPDAVEVAEVEEPT--SAGVVIEVHAAGVAFPDALLTRGR
MMAR_1498|M.marinum_M MRAIRVTRLDGPDAVEVAEVDEPT--GDGVVVDVHAAGVAFPDALLTRGL
MUL_2439|M.ulcerans_Agy99 MRAIRVTRLDGPDAVEVAEVDEPT--GDGVVVDVHAAGVAFPDALLTRGL
MAV_4021|M.avium_104 MRAARVTRLDGPDAIEVTDVDEPT--GDGVVVDVHAAGVAFPDALLTRGL
Mflv_4503|M.gilvum_PYR-GCK MRAIQIAELSGPGAARLVEIDEPAADDGTVLVEVHAAGVAFPDALQSRGL
Mvan_1864|M.vanbaalenii_PYR-1 MRAIQIAELGGPQAAALVEIDEPMGDDGTVLVDVHAAGVAFPDALQSRGL
TH_3116|M.thermoresistible__bu ---VQVSRLDGPEAVEVVEWEEPT-DSDAVIIDVHAAGVSFPDALLTRGL
MSMEG_2033|M.smegmatis_MC2_155 MRAALITRLDGPDAVEVVEVDEPS-GDDAVLIDVHAAGVAFPDALLTRGL
MAB_4603c|M.abscessus_ATCC_199 MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGE
MLBr_00118|M.leprae_Br4923 ---MHAIVAESANQMVWREVPDVTAGPGEVLIEVAASGVNRADVLQVAGK
.. : *:::* *:** .* * *
Mb3165|M.bovis_AF2122/97 YQYRPEPPFVLGAEIAGVVRSAPDNSQVRSGDRVVGLTMLTGGMAEVAVL
Rv3141|M.tuberculosis_H37Rv YQYRPEPPFVLGAEIAGVVRSAPDNSQVRSGDRVVGLTMLTGGMAEVAVL
MMAR_1498|M.marinum_M YQYRPQLPFVLGAEIAGVVRSAPPDCHVRAGDRVVGLTMLSGGMAEVAVL
MUL_2439|M.ulcerans_Agy99 YQYRPQLPFVLGAEIAGVVWSAPPDCHVRAGDRVVGLTMLSGGMAEVAVL
MAV_4021|M.avium_104 YQYRPELPFVLGAEIAGVVRSAPEGAHVRSGDRVVGLTMLSGGMAEVAVL
Mflv_4503|M.gilvum_PYR-GCK YQYKPEMPYTPGAEVAGVVRSAPAGAHVKAGDRVAGLTMLCGAMAEVVAL
Mvan_1864|M.vanbaalenii_PYR-1 YQYKPAMPYTPGAEVAGVVRSAPAGAHVQPGDRVAGLTMLCGAMAEVVAL
TH_3116|M.thermoresistible__bu YQYKPELPFIPGAEVAGEVRSAPAGAHVAKGDRVAGLTMLHGGMAEVVAL
MSMEG_2033|M.smegmatis_MC2_155 YQYKPDLPFSPGAEVAGVVRSAPAGASVAAGDRVLGLTMLSGGMAEVVAL
MAB_4603c|M.abscessus_ATCC_199 YQLKMEPPFVPGIETAGVVRSAPEGSGIKPGDRVMAFNFIGG-YAERVAV
MLBr_00118|M.leprae_Br4923 YPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGGYAEYVAV
* . * * ** * :.. . .: : * ** ..:
Mb3165|M.bovis_AF2122/97 SPERVFKLPDNMTFEAGAGVLFNDLTVYFALAVRGRLQAGETVLVHGAAG
Rv3141|M.tuberculosis_H37Rv SPERVFKLPDNMTFEAGAGVLFNDLTVYFALAVRGRLQAGETVLVHGAAG
MMAR_1498|M.marinum_M APDRVFRLPENVSFEAGAGLLFNDLTVYFALAVRGRLQRGETVLVHGAAG
MUL_2439|M.ulcerans_Agy99 TPDRVFRLPDNVSFEAGAGLLFNDLTVYFALAVRGRLQRGETVLVHGAAG
MAV_4021|M.avium_104 APDRVFKLPDNVSFEAGAGLLFNDLTVYFALTVRGRLQRGETVLVHGAAG
Mflv_4503|M.gilvum_PYR-GCK QPERVFALPDSVSFEAGAGILFNDLTVQFALRTRGRLAAGETVLVHGAAG
Mvan_1864|M.vanbaalenii_PYR-1 QPERVFKLPDSVSFEAGAGILFNDLTVHFALRTRGRLQQGETLLVHGAAG
TH_3116|M.thermoresistible__bu APDRVFKLPDAVSFEAGAGLLFNDLTVHCALRTRGRLSRGETVLVHGAAG
MSMEG_2033|M.smegmatis_MC2_155 PEDRVFKLPDAVPFDAGAGILFNDMTVHFVLRTRGRLSGGETVLVHGAAG
MAB_4603c|M.abscessus_ATCC_199 APSNILPTPPQLDDAEAVALIANYHTMYFAYARRGQLRAGETVLVLGAAG
MLBr_00118|M.leprae_Br4923 PASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLLLLHGGTS
..:: * : ...: *: .:* *: :*: *.:.
Mb3165|M.bovis_AF2122/97 GIGTSTLRLAPALGASRTVAVVSTQEKAELATVAGATDVV-LAEGFKDAV
Rv3141|M.tuberculosis_H37Rv GIGTSTLRLAPALGASRTVAVVSTQEKAELATVAGATDVV-LAEGFKDAV
MMAR_1498|M.marinum_M GIGTSALRLAPVLGASRTIAVVSSEEKSAIATAAGATDVV-LADGFKDTV
MUL_2439|M.ulcerans_Agy99 GIGTSALRLAPVLGASRTIAVVSSEEKSAIATAAGATDVV-LADGFKDTV
MAV_4021|M.avium_104 GIGTSALRLAPALGAARTIAVVSTTDKADIATAAGATDVV-LADGFKDAV
Mflv_4503|M.gilvum_PYR-GCK GIGTSTLRLAPAFGASRTIAVVSTEEKADVARAAGATDVV-LADGFKDAV
Mvan_1864|M.vanbaalenii_PYR-1 GIGTSALRLAPAFGASRTIAVVSSQDKAEVARAAGASEVV-LVDGFKDAV
TH_3116|M.thermoresistible__bu GIGTSTLRLAPAWGAARTIAVVSTEDKKAVATAAGADDVV-LADGFKDAV
MSMEG_2033|M.smegmatis_MC2_155 GIGSSVLRLAPALGAARTIAVVSTEEKGEIARAAGASDVV-LADGFRDAV
MAB_4603c|M.abscessus_ATCC_199 GIGTAAIQIAKGMG-AKVIAVVNRTAATEFVKSVGADIVLPLEEGWAKAV
MLBr_00118|M.leprae_Br4923 GIGSHGIQVARALG-AKVAVTAGSEEKLEFCRALGAQITINYRDEDFVAR
***: :::* * ::. .... . ** .: : :
Mb3165|M.bovis_AF2122/97 QELTNGRGVDIVVDPVGGDRFTDSLRSLAAGGRLLVIGFTGGEIPTVKVN
Rv3141|M.tuberculosis_H37Rv QELTNGRGVDIVVDPVGGDRFTDSLRSLAAGGRLLVIGFTGGEIPTVKVN
MMAR_1498|M.marinum_M KELTNGRGVDVVVDPVGGDRFTDSLRSLAPAGRLLVIGFTGGEIPTVKVN
MUL_2439|M.ulcerans_Agy99 KELTNGRGVDVVVDPVGGDRFTDSLRSLAPAGRLLVIGFTGGEIPTVKVN
MAV_4021|M.avium_104 KELTHGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGEIPTVKVN
Mflv_4503|M.gilvum_PYR-GCK KELTGGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGDIPTVKVN
Mvan_1864|M.vanbaalenii_PYR-1 KELTGGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVVGFTGGEIPTVKVN
TH_3116|M.thermoresistible__bu RELTGGRGVDIVVDPVGGDRFTDSLRSLAPGGRLLVLGFTAGEIPTVKVN
MSMEG_2033|M.smegmatis_MC2_155 KELTDGRGVDMVVDPVGGDRFTDSLRSLAVGGRLLVVGFTGGEIPQVKVN
MAB_4603c|M.abscessus_ATCC_199 REATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGFAAGGIPTIKVN
MLBr_00118|M.leprae_Br4923 LQQQNG-GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGGVKGELNLG
: * *.*:::* :*. : : :** *:*:*:*: .* :::.
Mb3165|M.bovis_AF2122/97 RLLLNNIDVVGVGWGAWSLTHPD----ALAQQWSQLERLLRSGKLPPPEP
Rv3141|M.tuberculosis_H37Rv RLLLNNIDVVGVGWGAWSLTHPD----ALAQQWSQLERLLRSGKLPPPEP
MMAR_1498|M.marinum_M RLLLNNIDVVGVGWGAWAGTHPG----ALAEQWAALESLLSSGALPPPEP
MUL_2439|M.ulcerans_Agy99 RLLLNNIDVVGVGWGAWAGTHPG----ALAEQWAALESLLSSGALPPPEP
MAV_4021|M.avium_104 RLLLNNIDVVGVGWGAWTGTHPG----ALAEQWAGLERLLTSGELAPPEP
Mflv_4503|M.gilvum_PYR-GCK RLLLNNVDAVGVGWGAWTMTHPG----YLQEQWAELEPLLASGTVPAPEP
Mvan_1864|M.vanbaalenii_PYR-1 RLLLNNVDAVGVGWGAWTMTHPG----FLQEQWAELEPLLASGAVAAPEP
TH_3116|M.thermoresistible__bu RLLLNNVDVVGVGWGAWTFAHPG----YLQEQWAELEPLLASGRVPAPEP
MSMEG_2033|M.smegmatis_MC2_155 RLLLNNIEVIGAGWGAWTFTHPG----YLQEQWAELEPLLASGAVAPPQV
MAB_4603c|M.abscessus_ATCC_199 RLLLRNASLIGVAWGEFLRTHAD----YLYETQAGLEKLVAEG-MRPPVS
MLBr_00118|M.leprae_Br4923 KVLSKRARIIGSTLRARPVNGPNSKSEIVAAVTASIWPMIADGSVRPIIG
::* .. :* .. : : : :: .* : .
Mb3165|M.bovis_AF2122/97 VVYPLDQAAAAIASLENRTAKGKVVLRVRD-----------
Rv3141|M.tuberculosis_H37Rv VVYPLDQAAAAIASLENRTAKGKVVLRVRD-----------
MMAR_1498|M.marinum_M AVYPLEQAGAAVASLENRTARGKVVLRVRG-----------
MUL_2439|M.ulcerans_Agy99 AVYPLEQAGAAVASLENRTARGKVVLRVRG-----------
MAV_4021|M.avium_104 VVYPLDEAAAAVASLENRTAKGKVVLRVRG-----------
Mflv_4503|M.gilvum_PYR-GCK VVYPLERAAEAIASLEDRSARGKVVVAVR------------
Mvan_1864|M.vanbaalenii_PYR-1 VVYPLERAAEAIASLENRSARGKVVVAVR------------
TH_3116|M.thermoresistible__bu VVYPLERAAEAIASLENRSAKGKVVLSVR------------
MSMEG_2033|M.smegmatis_MC2_155 EVYPLEQAAQAIASLENRSAKGKVVLKLR------------
MAB_4603c|M.abscessus_ATCC_199 ARIPLSEGRQALQDFADGKVYGKMVLVP-------------
MLBr_00118|M.leprae_Br4923 ARMAVQQAADAHQLLLSGKVSGKIVLTVAGSGTETLLSRHH
.:... * : . .. **:*: