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AALGYGVSDFVGGIASRRVAALRVVVISYPVALLLLVLAAVPFGGQLSTAAILWGLSAGIVQAFGVWWFY AALGSGPISVVSPLTAILVAGIPVLAGLAFGERPGTLAGVGVVLALIAVVLVSRDSAGDAEAARTGARFT AKVAWLTVGAGVAFGLNFVILHRIPKEAQLWPLVFGRAAAVVVVLIAAVATANLVIERGVPLRLAVLAGG LDTVANIATLVALQSSLLSLAGVLIALYPAATVVLAIAVLRERVSRSQCVGMVLALAAVGMIAAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4445 | - | - | 100% (276) | hypothetical protein Mflv_4445 |
| M. gilvum PYR-GCK | Mflv_0187 | - | 9e-06 | 25.78% (225) | amino acid permease-associated region |
| M. gilvum PYR-GCK | Mflv_3133 | - | 7e-05 | 25.91% (247) | hypothetical protein Mflv_3133 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0865 | - | 2e-05 | 30.41% (171) | integral membrane protein |
| M. tuberculosis H37Rv | Rv0842 | - | 2e-05 | 30.41% (171) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0415 | - | 1e-28 | 33.46% (272) | hypothetical protein MAB_0415 |
| M. marinum M | MMAR_4903 | - | 3e-05 | 23.77% (265) | hypothetical protein MMAR_4903 |
| M. avium 104 | MAV_4000 | - | 6e-71 | 58.57% (251) | hypothetical protein MAV_4000 |
| M. smegmatis MC2 155 | MSMEG_3416 | - | 2e-32 | 31.34% (284) | protein of unknown function DUF6, transmembrane, putative |
| M. thermoresistible (build 8) | TH_3271 | - | 5e-07 | 27.88% (226) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0503 | - | 2e-05 | 23.77% (265) | hypothetical protein MUL_0503 |
| M. vanbaalenii PYR-1 | Mvan_1917 | - | 1e-107 | 78.41% (264) | hypothetical protein Mvan_1917 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4445|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1917|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4000|M.avium_104 --------------------------------------------------
MSMEG_3416|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0415|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4903|M.marinum_M --------------------------------------------------
MUL_0503|M.ulcerans_Agy99 ---------------------------------------------MASST
Mb0865|M.bovis_AF2122/97 MRYTGPERCSGDGQVRAAGDRYSTVIWLLGGNLLVRSAGFGYPFLAYHVA
Rv0842|M.tuberculosis_H37Rv MRYTGPERCSGDGQVRAAGDRYSTVIWLLGGNLLVRSAGFGYPFLAYHVA
TH_3271|M.thermoresistible__bu --------------------------------------------------
Mflv_4445|M.gilvum_PYR-GCK --------------MAALGYGVSDFVGGIASRRVAALRVVVIS-YPVALL
Mvan_1917|M.vanbaalenii_PYR-1 -------------------------MGGIASRRVAALRVVVVS-YPVALV
MAV_4000|M.avium_104 --------------------------------------MMLVA-YPIETL
MSMEG_3416|M.smegmatis_MC2_155 ------MIGWLFGLGSAVLYGMSDFVGGLASRRSHFVVVALLG-QCAGLM
MAB_0415|M.abscessus_ATCC_1997 ------MNSIPLALAGSLSWGISDFIGGHASKRRSTLAVLALS-RPVGLA
MMAR_4903|M.marinum_M --------MPALAMGVTVTLWAFAFVGVRSAGRVFSPGVLALSRLFIAVM
MUL_0503|M.ulcerans_Agy99 TSSQRTVNMPALAMGVTVTLWAFAFVGVRSAGRVFSPGVLALSRLFIAVM
Mb0865|M.bovis_AF2122/97 GRGHGAGAVGAVVAAYGLGWAVGQLLCGWLVDRVG-ARVTLVSTMLVAAA
Rv0842|M.tuberculosis_H37Rv GRGHGAGAVGAVVAAYGLGWAVGQLLCGWLVDRVG-ARVTLVSTMLVAAA
TH_3271|M.thermoresistible__bu ------------VLGQGLAVLLAVCAAVFAAVGIVVRQRATMDVPPEKGV
:
Mflv_4445|M.gilvum_PYR-GCK LLVLAAVPFGGQ-LSTAAILWGLSAG-IVQAFGVWWFYAALGSGPISVVS
Mvan_1917|M.vanbaalenii_PYR-1 LLVLAAIPMGGQ-LSTAAVAWGALAG-LVQAFGVWWFYAALGSGPISVVS
MAV_4000|M.avium_104 LLGALAIFVGGP-IHPGALLWGGLYG-IGMAFGMWAFFAALGSGPISVVS
MSMEG_3416|M.smegmatis_MC2_155 ASALAGLMIGAESIPRSDLWWGALSG-FGTAVGMAFLFRGLSRGAMSVIV
MAB_0415|M.abscessus_ATCC_1997 VVGLVSVLTAST-HFDGRTLLGMLSG-PAAFAALYALYRALAIGPMGVVS
MMAR_4903|M.marinum_M VMAVIATIAATYTAYAGRATTRRLRPPSAAALTLVIAYGVAWFGAYSIVI
MUL_0503|M.ulcerans_Agy99 VMAVIATIAATYTAYAGRATTRRLRPPSAAALTLVIAYGVAWFGAYSIVI
Mb0865|M.bovis_AF2122/97 VLVLMAGLHTVPGLLVGAMIAGLVCDAPRPVLGAVIAELVADPQRRAQLD
Rv0842|M.tuberculosis_H37Rv VLVLMAGLHTVPGLLVGAMIAGLVCDAPRPVLGAVIAELVADPQRRAQLD
TH_3271|M.thermoresistible__bu STVMIATLVRRR-------LWWIGTG--AAVAGYALQAAALAFGSLILVQ
. :
Mflv_4445|M.gilvum_PYR-GCK ---------PLTAILVAGIPVLAGLAF------GERPGTLAGVGVVLALI
Mvan_1917|M.vanbaalenii_PYR-1 ---------PLTAVLVAGIPVLAGVAL------GERPSVVAGVGVVLALV
MAV_4000|M.avium_104 ---------PLAAVLNAAVPVAVGMAL------GERPGQAALVGVVLALA
MSMEG_3416|M.smegmatis_MC2_155 ---------PVSAVTGVSIPVLFGVVVE-----GQRPSLLAWLGIVVAVP
MAB_0415|M.abscessus_ATCC_1997 ---------PIAAVG-AVVPVLWGTVI------GQSLAGLTYLGLGGTLV
MMAR_4903|M.marinum_M SWAEQHIDAGTTALLVNLAPILVAVFAG--FFLGEGYSARLLTGIAIAFA
MUL_0503|M.ulcerans_Agy99 SWAEQHIDAGTTALLVNLAPILVAVFAG--FFLGEGYSARLLTGIAIAFA
Mb0865|M.bovis_AF2122/97 GWRYGWVLNIGAAITGGVGGVVAGWLDTPVLYWINGIGCAIFAGLAGRCI
Rv0842|M.tuberculosis_H37Rv GWRYGWVLNIGAAITGGVGGVVAGWLDTPVLYWINGIGCAIFAGLAGRCI
TH_3271|M.thermoresistible__bu P--------ILVSALLFALPLSARLGAR----RVSRGEWAWAAVLTVALA
: : . :
Mflv_4445|M.gilvum_PYR-GCK AVVLVSRDSAGD-----AEAARTGARFTAKVAWLTVGAGVAFGLNFVILH
Mvan_1917|M.vanbaalenii_PYR-1 AVVLVSRGAT-------DEDSRP-HRFTAKVAWLTVGSGVAFGMNFVILH
MAV_4000|M.avium_104 AVMLVSREAP---------AEGTPYRFTPKVAWLTVVAGSAMGLNLVFLH
MSMEG_3416|M.smegmatis_MC2_155 ALWLVAGRQS-----------RNAEGLKGSGVGDGLVAGVGIAVQYLALA
MAB_0415|M.abscessus_ATCC_1997 GVMLASASEG-----------LDGQRPGRQVLVWSFFCMVMFGICMILLA
MMAR_4903|M.marinum_M GVVLISAGGG-------------GSQTDWLGVGLGLLAAVLYAAGVLLQK
MUL_0503|M.ulcerans_Agy99 GVVLISAGGG-------------GSQTDWLGVGLGLLAAVLYAAGVLLQK
Mb0865|M.bovis_AF2122/97 PADVCRRTESGLRACTAMSKVGYRQALSDKRLVLLAVSGLATLTTLMGFF
Rv0842|M.tuberculosis_H37Rv PADVCRRTESGLRACTAMSKVGYRQALSDKRLVLLAVSGLATLTTLMGFF
TH_3271|M.thermoresistible__bu AFVLIAKPKP----------GDYQASIPGTVVVTVACVAGVTVCVVLAVR
: :
Mflv_4445|M.gilvum_PYR-GCK RIP-KEAQLWPLVFGRAAAVVVVLIAAVATANLVIERG--VPLRLAVLAG
Mvan_1917|M.vanbaalenii_PYR-1 QIP-PEAKLWPLVLGRLVAAAVVLFAALVTANLVFERG--VPLRLAVLAG
MAV_4000|M.avium_104 QAP-HACKLWPLVFARVAASLVVFAMAGTSQNLKMPRG--RPLRLAVAVA
MSMEG_3416|M.smegmatis_MC2_155 HAS-AASGLWPVAAGRVSAVLVLIVMAIFVMRHLKDEHDRSPLRTTMASG
MAB_0415|M.abscessus_ATCC_1997 EAG-RYHPVEAVVVSRATEVVLILILGALSWNNLRENLR-PPFGVVPFAG
MMAR_4903|M.marinum_M VALRTVDALSATLWGTLVGFIVTLPFLPAAARELSLASAADLWWLVFLGA
MUL_0503|M.ulcerans_Agy99 VALRTVDALSATLWGTLVGFIVTLPFLPAAARELSLASAADLWWLVFLGA
Mb0865|M.bovis_AF2122/97 AAVPMLMSASGLGVGAYGWVQLINALAVVAVTPLLTPWLSKQLALGPRPD
Rv0842|M.tuberculosis_H37Rv AAVPMLMSASGLGVGAYGWVQLINALAVVAVTPLLTPWLSKQLALGPRPD
TH_3271|M.thermoresistible__bu SLGWRRALLLATAVGVLFGVVAVLTKVWLHKLFTGGVAVGVTSPLLYLLI
.
Mflv_4445|M.gilvum_PYR-GCK GLDTVANIATLVALQSSLLS-------LAGVLIALYPAATVVLAIAVLRE
Mvan_1917|M.vanbaalenii_PYR-1 VLD---NVATLLALQSSMLS-------LAGVLIALYPAATVVLAIVVLRE
MAV_4000|M.avium_104 VLDIFANITMLAALHTWLLS-------LASILISLYPAATVVLAMVVLRE
MSMEG_3416|M.smegmatis_MC2_155 VLATSAGVLAAAALAAYAIATRHQLAAIAVVLSSMYPVIPVLLGVTVLRE
MAB_0415|M.abscessus_ATCC_1997 VLDTSAMLLFAYAAGHGSLA-------VAAVLSSLYPVVTVLIARLVLHE
MMAR_4903|M.marinum_M GPSAIAFTTWAYALARTNAG-------VTAATTLMVPALVIALSGLLLAE
MUL_0503|M.ulcerans_Agy99 GPSAIAFTTWAYALARTNAG-------VTAATTLMVPALVIALSGLLLAE
Mb0865|M.bovis_AF2122/97 ILAGAGVWVTLCMAAAGLARTTVG-FSVAAAACSPGEIAWFVVAAGIVHR
Rv0842|M.tuberculosis_H37Rv ILAGAGVWVTLCMAAAGLARTTVG-FSVAAAACSPGEIAWFVVAAGIVHR
TH_3271|M.thermoresistible__bu LLGVLATLLQQSAFHAGSLQAS------VPTMLVLEPVVAVALGAAVLGE
. . :. :: .
Mflv_4445|M.gilvum_PYR-GCK RVSRSQCVG-------MVLALAAVGMIAAG--------------------
Mvan_1917|M.vanbaalenii_PYR-1 RVTRWQALG-------MVLALGSVVMIAAN--------------------
MAV_4000|M.avium_104 RVTRWQGIG-------MVLAMGSVAMIASA--------------------
MSMEG_3416|M.smegmatis_MC2_155 HLTRQQSAG-------LLAAAAATVLLAV---------------------
MAB_0415|M.abscessus_ATCC_1997 RLSRVQQTG-------AVLTLVCVAVVVFSAAR-----------------
MMAR_4903|M.marinum_M VPNPLGLAGGGACLIGVALARGLLRLPARSRRRTGTGDQLQGVESLPVGL
MUL_0503|M.ulcerans_Agy99 VPNPLGLAGGGACLIGVVLARGLLRLPARSRRRTGTGDQLQGVESLPVGL
Mb0865|M.bovis_AF2122/97 IAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGF
Rv0842|M.tuberculosis_H37Rv IAPPAHGGRYHGIWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGF
TH_3271|M.thermoresistible__bu HLDINGWEP-------VPLALAGAAMFAATVALGRNEGAYEERLEVAALA
:
Mflv_4445|M.gilvum_PYR-GCK --------------------------------
Mvan_1917|M.vanbaalenii_PYR-1 --------------------------------
MAV_4000|M.avium_104 --------------------------------
MSMEG_3416|M.smegmatis_MC2_155 --------------------------------
MAB_0415|M.abscessus_ATCC_1997 --------------------------------
MMAR_4903|M.marinum_M SDYAASSTAPSGRQL-----------------
MUL_0503|M.ulcerans_Agy99 SDYAASSTAPSGRQL-----------------
Mb0865|M.bovis_AF2122/97 FGAALCLPLARVLAAASCGPLSSKEPSRDSYQ
Rv0842|M.tuberculosis_H37Rv FGAALCLPLARVLAAASCGPLSSKEPSRDSYQ
TH_3271|M.thermoresistible__bu QQSRSQQVRT----------------------