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LIKVMEGVRVLEVAQFTFVPAAGAILADWGADVIKIEHPVRGDTQRGFINMGGFQLDPNRHPLIEHPNRG KRSVGIDVSTPEGQEVLYEIAKTADVFLTNYMPQARQKNKFDIEHIRAVNPNIIYARGSAYGDKGPERLV GGFDGTAFWTRSGVGHALTPEELGGALPQGIPAFGDSIGGMNIAGGISAALFHRERTGEAVEIDVSLLST AWWAAGASVTQGMETGETMRSLMPGTTTSVNPFMANYQTSDGGTINLCIVSPTGYIRDTWEHLGLPELAD DPRFSDVMPLIQNAEEGVRLITEAIAAKPFEYWRRHLKTMKGQWAPFQSLVDLGTDEQAIANDMIVEVEA SDGGKPFKVVRGPVQFNHEPLETTRAPQASEHTEIVLMELGLEWDRIEELKDKGAIA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4341 | - | - | 100% (407) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. gilvum PYR-GCK | Mflv_2503 | - | 5e-99 | 45.43% (405) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. gilvum PYR-GCK | Mflv_4116 | - | 2e-46 | 33.08% (396) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 5e-29 | 29.06% (406) | hypothetical protein Mb3300 |
| M. tuberculosis H37Rv | Rv3272 | - | 1e-29 | 29.73% (407) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 4e-25 | 25.79% (380) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4009 | - | 0.0 | 77.23% (404) | dehydratase |
| M. avium 104 | MAV_1597 | - | 0.0 | 83.17% (404) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_0585 | - | 0.0 | 88.24% (408) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_2620 | - | 0.0 | 83.74% (406) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_3873 | - | 1e-164 | 74.79% (361) | dehydratase |
| M. vanbaalenii PYR-1 | Mvan_4155 | - | 3e-96 | 44.20% (405) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4341|M.gilvum_PYR-GCK -----MIKVMEGVRVLEVAQFTFVPAAGAILADWGADVIKIEHPVRGDTQ
MSMEG_0585|M.smegmatis_MC2_155 -----MIKVMQGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQ
TH_2620|M.thermoresistible__bu -MTEKTTRVMQGVRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQ
MAV_1597|M.avium_104 ---------MQGFRVLEVAQFTFVPAAGAILADWGADVIKVEHPVRGDTQ
MMAR_4009|M.marinum_M ---------MAGYRVLEVAQFTFVPAAGAILADWGADVIKVEHPRRGDTQ
MUL_3873|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4155|M.vanbaalenii_PYR-1 -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
MAB_0824|M.abscessus_ATCC_1997 ----MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGDDT
Mflv_4341|M.gilvum_PYR-GCK RGFINMGGFQLDPNRHPLIEHPNRGKRSVGIDVSTPEGQEVLYEIAKTAD
MSMEG_0585|M.smegmatis_MC2_155 RGFINMGGFQLDPNRHPLIEHPNRGKRSVGIDVSKPEGQEVLYELAQVSD
TH_2620|M.thermoresistible__bu RGFIHMGGFELNPDRHPLIEHPNRGKRSIGIDISTDGGREVLYEIAKTSD
MAV_1597|M.avium_104 RGFVNMGGIQVDPERHPLMEHPNRGKRSVGVDVSTPGGQEVIYELAKTSD
MMAR_4009|M.marinum_M RGFLNVGGIALDPERHPLIEHPNRGKRSVGIDLATSDGQDVLHELARTAD
MUL_3873|M.ulcerans_Agy99 MAFSTWGGIALDPERHPLIEHPNRGKRSVGIDLATSDGQDVLHELARSAD
Mvan_4155|M.vanbaalenii_PYR-1 RGLRQTGLLRVEGDPNPNIEHANRLKRSIGLDMSVAEGREVLLELARRAD
Mb3300|M.bovis_AF2122/97 Q---ITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
Rv3272|M.tuberculosis_H37Rv Q---ITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
MAB_0824|M.abscessus_ATCC_1997 R---QWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRAD
. . : ** *:*: :*:: .:. .:* :*
Mflv_4341|M.gilvum_PYR-GCK VFLTNYMPQARQKNKFDIEHIRAVNPNIIYARGSAYGDKGPERLVGGFDG
MSMEG_0585|M.smegmatis_MC2_155 VFLTNYMPQAREKNKFDVEHIRAVNPNIIYARGSAYGDKGPERLAGGFDG
TH_2620|M.thermoresistible__bu VFLTNYLPVQRQKHKFDVEHIREVNPGIIYARGSAYGDKGPQRDVGGFDG
MAV_1597|M.avium_104 VFLTNYMPAQRRKHKFDVEHIRAVNPNIVYARGSAYGDKGAERDVGGYDG
MMAR_4009|M.marinum_M VFLTNYLPSARQKNKFDVEHVRGANPDIIYARGTAYGDKGAERDVGGYDG
MUL_3873|M.ulcerans_Agy99 VFLTNYLPSARQKNKFDVEHVRGANPDIIYARGTAYGDKGAERDVGGYDG
Mvan_4155|M.vanbaalenii_PYR-1 VFLTSFLPGHRQKFGIDVDDIRAANPKIVYARGSALGPRGEESVKGGYDM
Mb3300|M.bovis_AF2122/97 VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
Rv3272|M.tuberculosis_H37Rv VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
MAB_0824|M.abscessus_ATCC_1997 VVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFG-RGAGADLPGYDL
*.: : . .* :. : :: ** ::*. :. * .* * *
Mflv_4341|M.gilvum_PYR-GCK TAFWTRSGVGHALTPEELGGALPQGIPAFGDSIGGMNIAGGISAALFHRE
MSMEG_0585|M.smegmatis_MC2_155 TAFWTRSGVGHALTPEELGGALSQGIPAFGDSIGGMNIAGGIAAALFHRD
TH_2620|M.thermoresistible__bu TAFWTRSGIGHALTPEELGGALSQGIPAFGDSIGGMNIAGGIAAALFHRE
MAV_1597|M.avium_104 TAFWTRSGIGYALTPEELGGALGQGIPAFGDSIGGMFIAGGISAALLHRE
MMAR_4009|M.marinum_M TAFWTRSGVGHALTPPELGAPLAQGIPAFGDSIGGMNIAGGISAALLHRE
MUL_3873|M.ulcerans_Agy99 TAFWTRSGVGHALTPPELGAPLAQGIPAFGDSIGGMNIAGGISAALLHRE
Mvan_4155|M.vanbaalenii_PYR-1 TAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALLKRE
Mb3300|M.bovis_AF2122/97 VVAAEAGMTTGMPTPEGKPQIIP---FQLVDNASGHVLAQAVLAALLHRE
Rv3272|M.tuberculosis_H37Rv VVAAEAGMTTGMPTPEGKPQIIP---FQLVDNASGHVLAQAVLAALLHRE
MAB_0824|M.abscessus_ATCC_1997 LVQAVGGLMSVTGPDAAHPSKVG---VALVDVLTALHALSGILAALSYRD
. . . : * . .: *** *:
Mflv_4341|M.gilvum_PYR-GCK RTGEAVEIDVSLLSTAWWAAGASVTQGMETGETMRSLMPGTT--------
MSMEG_0585|M.smegmatis_MC2_155 RTGEALEVDVSLLSTAWWAAGASVTQGMETGETMRSQMPDTIG-------
TH_2620|M.thermoresistible__bu RTGEAVEIDVSLLSTAWWAAGASVTQGMETGETMRSQMPDTVG-------
MAV_1597|M.avium_104 RTGEAVELDVSLLSTAWWAAGASVTQGMETGEVMRTPMPGAGA-------
MMAR_4009|M.marinum_M RTGEALEVDVSLLSTAWWAAGASVTQGMDTGETMRSRMPQSGG-------
MUL_3873|M.ulcerans_Agy99 RTGEALEVDVSLLSTAWWAAGASMTQGMDTGETMRSRMPQSGG-------
Mvan_4155|M.vanbaalenii_PYR-1 RTGEPSIVDVSLLGSGLWALGHTVALTNHLHERMEAFPPGAHG-------
Mb3300|M.bovis_AF2122/97 RNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGV
Rv3272|M.tuberculosis_H37Rv RNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGV
MAB_0824|M.abscessus_ATCC_1997 RTGQGQRVDTDLMSVLLSSLVNQASGYLGAGVVPEALGNRHP--------
*.* ::. : . ..
Mflv_4341|M.gilvum_PYR-GCK -TSVNPFMANYQTSDGGTINLCIVSPTGYIRDTWEHLGLPELADDPRFSD
MSMEG_0585|M.smegmatis_MC2_155 -PTVNPFLGNYQTSDGGTINLCIVSPTGYIRDTFEHLGLAELADDPRFCD
TH_2620|M.thermoresistible__bu -PTVNPFLGNYLTSDGGTINLCIVSPTGYIRDAFEHLDLPELADDPRFCD
MAV_1597|M.avium_104 -PSVNPFMGNYETSDGGTINLCIISPTGLIRDTFEHLGIPEAADDPRFCD
MMAR_4009|M.marinum_M -MPMNPFMGNYQTSDGGTINLCILSPTGYIRDTFEHLGIPEAADDPRFGE
MUL_3873|M.ulcerans_Agy99 -MPMNPFMGNYQTSDGGTINLCILSPTGYIRDTFEHLGIPEAADDPRFGE
Mvan_4155|M.vanbaalenii_PYR-1 -SPINPLVGLYPTADDRYISFVMMQPTKFWADVCSHMDLDELVDDPRFAT
Mb3300|M.bovis_AF2122/97 GFATQPSD-AFRTADG-YIVISAYVPK-HWQKLCYLIGRPDLVEDQRFAE
Rv3272|M.tuberculosis_H37Rv GFATQPSD-AFRTADG-YIVISAYVPK-HWQKLCYLIGRPDLVEDQRFAE
MAB_0824|M.abscessus_ATCC_1997 --SIAPYQ-TFETADR-PIAIAVGNDK-QFRLLVQALEMPRLARDDRFAT
. * : *:* * : . : . * **
Mflv_4341|M.gilvum_PYR-GCK VMPLIQNAEEGVRLITEAIAAKPFEYWRRHLKTMKGQWAPFQSLVDLGTD
MSMEG_0585|M.smegmatis_MC2_155 VLPLIEHAAEAAERIAEAIRSRPFEYWRRHLKTMKGQWAPFQSLVDLATD
TH_2620|M.thermoresistible__bu VMPLFENAAEAARLIADSIRSKPFDYWRERLKTMKGQWAPFQSLVDLAGD
MAV_1597|M.avium_104 VLPLIQNADAAAELIAKAFAAKPFDYWRQHLKTMKGQWAPFQSLLDLIDD
MMAR_4009|M.marinum_M AEQLLRNADAAGALIARAVAARPFEYWRQRLKTMKGQWAPFQSLIELADD
MUL_3873|M.ulcerans_Agy99 AEQLLRNADAAGALIARAVAARPFEYWRQRLKTMKGQWAPFQSLIELADD
Mvan_4155|M.vanbaalenii_PYR-1 AESIAENTADAAEILKEAMSKRTLAEWSERFATLAGPWAPVQDTLQAAED
Mb3300|M.bovis_AF2122/97 QRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDT
Rv3272|M.tuberculosis_H37Rv QRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDT
MAB_0824|M.abscessus_ATCC_1997 NPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFRF
: : . : * : : : :
Mflv_4341|M.gilvum_PYR-GCK EQAIANDMIVEVEASDGGKPFKVVRGPVQFNHEPLETTRAPQASEHTEIV
MSMEG_0585|M.smegmatis_MC2_155 EQAIANDMVVEVEAADGGEPFRVVRGPVQFNHEPLETTRAPQASEHTEVV
TH_2620|M.thermoresistible__bu EQAIANDMIVEVDAADGGPPFKVVRGPVQFNHEPLRTTRAPLASEHTELI
MAV_1597|M.avium_104 EQAIANDMIAEVELAGGGKPFRVVRGPVQFNHEPLATTRAPQASEHTELV
MMAR_4009|M.marinum_M EQALANDMVAEVDLGAGGPPFRVVRGPVQFNHEPLTTTRAPQPGEHTETV
MUL_3873|M.ulcerans_Agy99 EQALANDMVAEVDLGAGGPPFRVVRGPVQFNHEPLTTTRAPQPGEHTETV
Mvan_4155|M.vanbaalenii_PYR-1 AQVRANEYLVQAG------ELELVANPVQFDVAAPASGPAPGFAEQTDDI
Mb3300|M.bovis_AF2122/97 PLFAESDLTLEVG--RGADTITVIRTPARYASFRAVVTDPPPTAGEHNAV
Rv3272|M.tuberculosis_H37Rv PLFAENDLTLEVG--RGADTITVIRTPARYASFRAVVTDPPPTAGEHNAV
MAB_0824|M.abscessus_ATCC_1997 AERLGLDVAVTVP--GSPE--PQVANPISMSKTPVVYRNGPPRLGQSRA-
: . : * * .
Mflv_4341|M.gilvum_PYR-GCK LMELGLEWDRIEELKDKGAIA
MSMEG_0585|M.smegmatis_MC2_155 LMELGLDWDRIGKLKDVGAIA
TH_2620|M.thermoresistible__bu LMDIGMDWDRISELKDSGAIA
MAV_1597|M.avium_104 LMELGMDWDRIEELKNAGAIA
MMAR_4009|M.marinum_M LLELGMDWDRIDQLKRSGAIS
MUL_3873|M.ulcerans_Agy99 LLELGMDWDRIDQLKRSGAIS
Mvan_4155|M.vanbaalenii_PYR-1 LVELGLDWDRIIELKTAGAVT
Mb3300|M.bovis_AF2122/97 FLARP----------------
Rv3272|M.tuberculosis_H37Rv FLARP----------------
MAB_0824|M.abscessus_ATCC_1997 ---------------------