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M. gilvum PYR-GCK Mflv_4213 (-)

annotation: Dak phosphatase
coordinates: 4472116 - 4473759
length: 547

SARRLDASTLRRWAHDAVAALISHTDEINRLNVFPVADADTGTNMLFTMRAAWAQADSDAADDVTAITAA
LAAGALRGARGNSGVILSQILRALAEVTAEAAEERGGVLSEVTGEMLAAALRHAVTLVVASMGEAVPGTI
VSVLHDAAAAAEDAVCGQADLAAVVVACTQAAAAALDRTPTQLDVLADAGVVDAGGRGLLVLLDALSAIL
TGELTRRQVYLPDPKHAAGAAAPPSPTPGFEVMYLLSDCDAENVEQLRARLDALGDSVAIAASGFGEAGA
GHYSVHVHADDAGAAVEAGLAVGTLSRIQITSLHGGADRSSAGSWGRERAVLAVVDGEGAEELFVGEGAA
VLRTEPGVEISAQQLLHALVKTGAAQVMVLPNGYVAAEEIVAGCAVAADWGIDLVPIPTGSMVQGLAALA
VHDPGHRLVDDGYTMARAGAAARFGSVRIAAEDALTWAGACRPGDGLGITGDEVVVVGDDIVSAATGLID
LLLAAGGELVTVLTGDGVESEVGAALAEHVHHNHLGAELVTFHTGHRADALLIGVE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4213--100% (547)Dak phosphatase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2999c-0.063.42% (555) hypothetical protein Mb2999c
M. tuberculosis H37RvRv2974c-1e-15662.89% (477) hypothetical protein Rv2974c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3279c-1e-14351.78% (562) putative phosphatase/kinase
M. marinum MMMAR_1741-1e-17961.13% (566) hypothetical protein MMAR_1741
M. avium 104MAV_3819-1e-17761.79% (560) DAK2 domain-containing protein
M. smegmatis MC2 155MSMEG_2402-0.067.44% (559) dihydroxyacetone kinase
M. thermoresistible (build 8)TH_0233-1e-13565.89% (384) CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN
M. ulcerans Agy99MUL_3169-8e-0522.90% (393) PPE family protein
M. vanbaalenii PYR-1Mvan_2154-0.078.22% (551) Dak phosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           MNFSVLPPEINSLRLFSDAGSTSMLEAAAAWGSLADELQVAASSFSSVTA
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           GLASGAWQGPASAAMSAVAAPYASWLSAAAAQAAGTAGRASAAAAVFEAA
                                                                                      

Mb2999c|M.bovis_AF2122/97           ---------------------------------MG----TADRPLDASAL
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               ---------------------------------MG----TTERPLDALAL
MAV_3819|M.avium_104                ------------------------MAAQRRWVTLGSSWTSHDRPLDAAAL
Mflv_4213|M.gilvum_PYR-GCK          ---------------------------------------MSARRLDASTL
Mvan_2154|M.vanbaalenii_PYR-1       ---------------------------------------MSARRLDASAL
MSMEG_2402|M.smegmatis_MC2_155      ---------------------------------------MSARRLDASAL
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      ---------------------------------------MRLSVLDSAAL
MUL_3169|M.ulcerans_Agy99           QAAIVHPAMVAANRNELVALVISNLFGQNAPAIAATEAVYEQLWAQDVAV
                                                                                      

Mb2999c|M.bovis_AF2122/97           RDWAHAVVSDLILHIDEINRLNVFPVADSDTGVNML----FTMRAAVVEA
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               RDWAHTGVSDLITHLDEINRLNVFPVADSDTGANML----FTMRSALAQV
MAV_3819|M.avium_104                RDWAHTAVSDLITHIDEINRLNVFPVADSDTGANML----FTMRSALAEL
Mflv_4213|M.gilvum_PYR-GCK          RRWAHDAVAALISHTDEINRLNVFPVADADTGTNML----FTMRAAWAQA
Mvan_2154|M.vanbaalenii_PYR-1       RHWAHAAVADLISHTDEINQLNVFPVADADTGTNML----FTMRAAWAEA
MSMEG_2402|M.smegmatis_MC2_155      RDWAHTAVGDLITHTDEINRLNVFPVADADTGTNML----FTMRSAWAHA
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      LDWARASVEGLISRSDEINRLNVFPVADADTGTNML----FTMRSAVNAA
MUL_3169|M.ulcerans_Agy99           MAGYHAGVSAIAQQLAPWQQALALPAADADFSLSIFGLQLVKTGTANATT
                                                                                      

Mb2999c|M.bovis_AF2122/97           DLHANS------QADAEDVARVAAALAAGALNGARG--------------
Rv2974c|M.tuberculosis_H37Rv        ------------------------------MNGARG--------------
MMAR_1741|M.marinum_M               DSTGGAGPEHPEDPEHRDVAQVAAALAAGALNGARG--------------
MAV_3819|M.avium_104                QAAGGPG----------CVARAAAALSTGALNGARG--------------
Mflv_4213|M.gilvum_PYR-GCK          DS-DAADD----------VTAITAALAAGALRGARG--------------
Mvan_2154|M.vanbaalenii_PYR-1       DSCDAGDD----------VTAVAAALAGGALHGARG--------------
MSMEG_2402|M.smegmatis_MC2_155      DA-QSGGD----------VAQVASALAAGALQGARG--------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      EALGEGAT----------VAQVAAALARGAVHGARG--------------
MUL_3169|M.ulcerans_Agy99           TFGGLAIASGANSSADAGVADIAFAFGSGSSASATGGVLNIAGVGGANSS
                                                                                      

Mb2999c|M.bovis_AF2122/97           ----------------NSGVILSQILRGIAEVTATAAAASGAVLRAVDA-
Rv2974c|M.tuberculosis_H37Rv        ----------------NSGVILSQILRGIAEVTATAAAASGAVLRAVDA-
MMAR_1741|M.marinum_M               ----------------NSGVILSQILRGVSDVTDSAAAG--QPLAAIDA-
MAV_3819|M.avium_104                ----------------NSGVILSQILRGVADVTATAAARAGGQLAHIEA-
Mflv_4213|M.gilvum_PYR-GCK          ----------------NSGVILSQILRALAEVTAEAAEERGGVLSEVTG-
Mvan_2154|M.vanbaalenii_PYR-1       ----------------NSGVILSQILRAVAEVTASAAEDRDGVLADITG-
MSMEG_2402|M.smegmatis_MC2_155      ----------------NSGVILSQILLGLAEVITSAAADRGGDLLDVDG-
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      ----------------NSGVILSQIVRGIADAAD--------DQDAIGA-
MUL_3169|M.ulcerans_Agy99           ASATGGINIGTGALAVGDGNTVNASSIGVANIGTVAAAFGNNSVTAIANG
                                                                                      

Mb2999c|M.bovis_AF2122/97           ----NALGAALWRGVELVVASMGGVEVPGTIVSVLRAAAGAVDQCAH--E
Rv2974c|M.tuberculosis_H37Rv        ----NALGAALWRGVELVVASMGGVEVPGTIVSVLRAAAGAVDQCAH--E
MMAR_1741|M.marinum_M               ----ALLAAALWRGVELVITSMGGEEVPGTIVSVLRAAAVAVRQCADAGE
MAV_3819|M.avium_104                ----AVLGAALQRGVELVIASMGGEEIPGTIVSVLRAAATAVAQCARAGE
Mflv_4213|M.gilvum_PYR-GCK          ----EMLAAALRHAVTLVVASMG-EAVPGTIVSVLHDAAAAAEDAVCGQA
Mvan_2154|M.vanbaalenii_PYR-1       ----PLLSSALRHAVTLVVTSMG-EAVPGTIVSVLHDAAEAAEEAVSAEA
MSMEG_2402|M.smegmatis_MC2_155      ----PLFGAALRHGVALVAVSMG-DPVPGTIVTVLQAAADAAEKCVVGGA
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      ----EVVRRALRQASQFVIASMS-TPVEGTIVSVLAAAADAADDAQS--D
MUL_3169|M.ulcerans_Agy99           VENNATVAAAFGNNNTDVSAIVNGVENTGVVSAVFGSDNSGVSANAFGVE
                                                                                      

Mb2999c|M.bovis_AF2122/97           GLAGAVTAAGDAAVIALEKT------------------PEQLDVLADAGA
Rv2974c|M.tuberculosis_H37Rv        GLAGAVTAAGDAAVIALEKT------------------PEQLDVLADAGA
MMAR_1741|M.marinum_M               GLAAAVAAAGDAAVVALEKT------------------PEQLDVLADAGV
MAV_3819|M.avium_104                GVTAAVIAAGDAAVIALEKT------------------PEQLDVLADAGA
Mflv_4213|M.gilvum_PYR-GCK          DLAAVVVACTQAAAAALDRT------------------PTQLDVLADAGV
Mvan_2154|M.vanbaalenii_PYR-1       ELADVVAACAHAAGAALDRT------------------PTQLDVLADAGV
MSMEG_2402|M.smegmatis_MC2_155      DLAEVAASAADAAATALERT------------------PQQLDVLAEAGV
TH_0233|M.thermoresistible__bu      ----VVSTAAEAAVVALEKT------------------PEQLDVLARAGV
MAB_3279c|M.abscessus_ATCC_199      DLPVLVTTAADAAVSALEKT------------------PKQLDVLADNGV
MUL_3169|M.ulcerans_Agy99           NNAIVATAAGSGNSNVMANAGGVGANEILVAAALGNNNSAIANATGVGGT
                                         . :.  .   .: .:                  .   :. .  *.

Mb2999c|M.bovis_AF2122/97           VDAGGRGLLVLLDALRSTICGQAPA---------------RAVYEPSPRA
Rv2974c|M.tuberculosis_H37Rv        VDAGGRGLLVLLDALRSTICGQAPA---------------RAVYEPSPRA
MMAR_1741|M.marinum_M               VDAGGRGLLVLLDALRSTITGAAPA---------------RSVYEPAPRS
MAV_3819|M.avium_104                VDAGGRGLLVLLDALRTTITGQAPA---------------RTVYRLAPRT
Mflv_4213|M.gilvum_PYR-GCK          VDAGGRGLLVLLDALSAILTGELTR---------------RQVYLPDPKH
Mvan_2154|M.vanbaalenii_PYR-1       VDAGGRGLVVLLDALCATLTGHAPR---------------RGVYQPSPNK
MSMEG_2402|M.smegmatis_MC2_155      VDSGGRGLLVLLDAMTATITGHAPR---------------RPAYTPAPPR
TH_0233|M.thermoresistible__bu      VDAGGRGFVALLDALTLTLTGQLPY---------------RPEYRPAPPE
MAB_3279c|M.abscessus_ATCC_199      VDAGARGLVVILDALVSVVAGELPS---------------RREYSPSPPK
MUL_3169|M.ulcerans_Agy99           LGTGAISLIGNNNTLYADATGAGHIGTVASALFGDNNGVKATSFGLNNIA
                                    :.:*. .::   :::     *                      :      

Mb2999c|M.bovis_AF2122/97           LPTDTAT----------------QRPAPQFEVMYLLAVCDAAAADQLRDR
Rv2974c|M.tuberculosis_H37Rv        LPTDTAT----------------QRPAPQFEVMYLLAVCDAAAADQLRDR
MMAR_1741|M.marinum_M               PALGVGV----------------PAPIPQFEVMYLLAGCDAAAADTLRDR
MAV_3819|M.avium_104                AAPEAAA----------------PRPAPQFEVMYRLDDCAPAAADALRDR
Mflv_4213|M.gilvum_PYR-GCK          AAGAAAP----------------PSPTPGFEVMYLLSDCDAENVEQLRAR
Mvan_2154|M.vanbaalenii_PYR-1       SSAPSSA----------------AHATPSFEVMYLLADCHAEDIEKLRAA
MSMEG_2402|M.smegmatis_MC2_155      ATASSSVSARAGVPADDV----APTQVPQFEVMYLLSGCAPEAVEHLRAG
TH_0233|M.thermoresistible__bu      PAVTTPA----------------APAPPQFEVMYLLSGCDARGVERLRRR
MAB_3279c|M.abscessus_ATCC_199      NAPSQVWVAGPGRGGGGLNLDPPRELPPEFEVMYLLCGCDELQIADLRAQ
MUL_3169|M.ulcerans_Agy99           TVATAGGSGNTTVAAEASGAENVAVLATAFGNNNPTVTANVLGAGNLATA
                                                               . *        .       *   

Mb2999c|M.bovis_AF2122/97           LKELGESVAIAA----------------------------APP-------
Rv2974c|M.tuberculosis_H37Rv        LKELGESVAIAA----------------------------APP-------
MMAR_1741|M.marinum_M               LSELGDSVAIAA----------------------------APS-------
MAV_3819|M.avium_104                LTELGDSVGIAS----------------------------APSSAQ----
Mflv_4213|M.gilvum_PYR-GCK          LDALGDSVAIAA----------------------------SGFGEAG---
Mvan_2154|M.vanbaalenii_PYR-1       LEELGDSIAIAA----------------------------SGFGEAGGAG
MSMEG_2402|M.smegmatis_MC2_155      LEQIGESVAIAT----------------------------SGG-------
TH_0233|M.thermoresistible__bu      LSEIGESVAVAA----------------------------SGS-------
MAB_3279c|M.abscessus_ATCC_199      LDAMGDSIAIAG----------------------------DGE-------
MUL_3169|M.ulcerans_Agy99           ATALGNNNTINANVVGLENIATVATAGGNDNGVGASGVGVGGNIGNIATA
                                       :*:.  :                                        

Mb2999c|M.bovis_AF2122/97           -DSYSVHVHTDDAGA-----------------------------------
Rv2974c|M.tuberculosis_H37Rv        -DSYSVHVHTDDAGA-----------------------------------
MMAR_1741|M.marinum_M               -ESYSVHVHTDDAGA-----------------------------------
MAV_3819|M.avium_104                -HTYSVHVHTDDAGA-----------------------------------
Mflv_4213|M.gilvum_PYR-GCK          AGHYSVHVHADDAGA-----------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       PGHYSVHVHADDAGA-----------------------------------
MSMEG_2402|M.smegmatis_MC2_155      -DRYSVHVHVDDAGA-----------------------------------
TH_0233|M.thermoresistible__bu      -GGYSVHVHCDDAGG-----------------------------------
MAB_3279c|M.abscessus_ATCC_199      -MGHSVHAHVNDAGA-----------------------------------
MUL_3169|M.ulcerans_Agy99           FGNSNSQVSADASGAGGNLGTVATAFGNENNVTASAFGAGNIGNVSSALF
                                        . :.  : :*.                                   

Mb2999c|M.bovis_AF2122/97           -----------------------------AVEAGLAVGRVSRIVISALGS
Rv2974c|M.tuberculosis_H37Rv        -----------------------------AVEAGLAVGRVSRIVISALGS
MMAR_1741|M.marinum_M               -----------------------------AVEAGLAAGRLSKIVISALSS
MAV_3819|M.avium_104                -----------------------------AVEAGLAAGRLSRIVISALSS
Mflv_4213|M.gilvum_PYR-GCK          -----------------------------AVEAGLAVGTLSRIQITSLHG
Mvan_2154|M.vanbaalenii_PYR-1       -----------------------------AVEAGLAVGSLSRIQITSLSG
MSMEG_2402|M.smegmatis_MC2_155      -----------------------------AVEAGLAVGTLNRIQITALTG
TH_0233|M.thermoresistible__bu      -----------------------------AVEAGLACGVPSRIQITALSG
MAB_3279c|M.abscessus_ATCC_199      -----------------------------AIEAGMKFGTPQSIQISSLRG
MUL_3169|M.ulcerans_Agy99           SNNNTISASSIGVENIGTVATSIGDNNTVSATNGLGLGGNIATVATALGG
                                                                 :   *:  *       ::* .

Mb2999c|M.bovis_AF2122/97           GTSGLPAG---GWTRGRAVLAVVDGDGAAELFAGE---------------
Rv2974c|M.tuberculosis_H37Rv        GTSGLPAG---GWTRGRAVLAVVDGDGAAELFAGE---------------
MMAR_1741|M.marinum_M               GTTALAAG---GWTRQRAVLAVVDGDGAAELFAAE---------------
MAV_3819|M.avium_104                GGPGLPAG---GWTRERAVLAVVDGDGAAGLFSGE---------------
Mflv_4213|M.gilvum_PYR-GCK          GADRSSAG---SWGRERAVLAVVDGEGAEELFVGE---------------
Mvan_2154|M.vanbaalenii_PYR-1       GGDRHPAG---GWSRQRAVLAVVDGDGAESLFTGE---------------
MSMEG_2402|M.smegmatis_MC2_155      SGGSRPSG---GWERERAVLAVVDGDGGAELFAGE---------------
TH_0233|M.thermoresistible__bu      -GAAHPAA---GWSRERAALAVVDGDGAAELFATE---------------
MAB_3279c|M.abscessus_ATCC_199      GLDVPGGGHHDGRHRHRRVLALAEGDGAATLFSSE---------------
MUL_3169|M.ulcerans_Agy99           QNNTVSAETGTGGANIASVSTVLFGENNTASASAVGAGNIANVATVSFCD
                                          .    .  .   . ::  *:.                       

Mb2999c|M.bovis_AF2122/97           -----------------------------------GACVLRPGPDAVTPA
Rv2974c|M.tuberculosis_H37Rv        -----------------------------------GACVLRPGPDAVTPA
MMAR_1741|M.marinum_M               -----------------------------------GACVLRPGAGAAAPA
MAV_3819|M.avium_104                -----------------------------------GACVLQRDPAAADPV
Mflv_4213|M.gilvum_PYR-GCK          -----------------------------------GAAVLRT-----EPG
Mvan_2154|M.vanbaalenii_PYR-1       -----------------------------------GAEILRP-----QSD
MSMEG_2402|M.smegmatis_MC2_155      -----------------------------------GAHVLRP-----EAD
TH_0233|M.thermoresistible__bu      -----------------------------------GAHVLRR-----DPD
MAB_3279c|M.abscessus_ATCC_199      -----------------------------------GAQVLRVD------E
MUL_3169|M.ulcerans_Agy99           NNTSNASSFGVENIAAVATSYGDGNTVTATNSLGLGGNIATVATALGGQD
                                                                       *. :           

Mb2999c|M.bovis_AF2122/97           ADISAHQLVRAVVDTGAAHVMVLPNGYVAAEELVAG--------------
Rv2974c|M.tuberculosis_H37Rv        ADISAHQLVRAVVDTGAAHVMVLPNGYVAAEELVAG--------------
MMAR_1741|M.marinum_M               SDLSAHQLVRAVVDTGAAQVMVLPNGYVAVEELVAG--------------
MAV_3819|M.avium_104                TTISAHQLMRAVVDTGAAQVMVLPNGYVAAEELVAG--------------
Mflv_4213|M.gilvum_PYR-GCK          VEISAQQLLHALVKTGAAQVMVLPNGYVAAEEIVAG--------------
Mvan_2154|M.vanbaalenii_PYR-1       VPVSAQQLLHALVNTGAAQVMVLPNGYVAAEEIVAG--------------
MSMEG_2402|M.smegmatis_MC2_155      EPVSAKQLLRALVDVGAAQVMVLPNGYVAAEELVAG--------------
TH_0233|M.thermoresistible__bu      TPVTAQQLLRALVDTGAGQVMVLPNGYVAAEELVAG--------------
MAB_3279c|M.abscessus_ATCC_199      PPASAKRLLDAVVDSGAHQIMVLPNGLMAAEELVAV--------------
MUL_3169|M.ulcerans_Agy99           NTVSAQAGAGGANIAQVATVLFGDNNTASASGLGAGNIADVATVLFSNNN
                                       :*:    .     .  ::.  *.  :.. : *               

Mb2999c|M.bovis_AF2122/97           -------------------------CTAAIGWGVDVVPVPTGSMVQG---
Rv2974c|M.tuberculosis_H37Rv        -------------------------CTAAIGWGVDVVPVPTGSMVQG---
MMAR_1741|M.marinum_M               -------------------------CTAAIGWGVDVVPVPTGSMVQG---
MAV_3819|M.avium_104                -------------------------CTAAIGWGIDVVPIPTESMVQG---
Mflv_4213|M.gilvum_PYR-GCK          -------------------------CAVAADWGIDLVPIPTGSMVQG---
Mvan_2154|M.vanbaalenii_PYR-1       -------------------------CAVASDWGIDMVPVPTGSMVQG---
MSMEG_2402|M.smegmatis_MC2_155      -------------------------CTAAIGWGIDVVPVPAGSMVQG---
TH_0233|M.thermoresistible__bu      -------------------------CTAAISWGIDVVPVPAASMVQG---
MAB_3279c|M.abscessus_ATCC_199      -------------------------CAAARGWGITVIPLPSASMAQG---
MUL_3169|M.ulcerans_Agy99           TSTASALGVENIATIVTSYGDNNNVSATAPGIGANIATVATALGGQGNTV
                                                             .:.* . *  : .:.:    **   

Mb2999c|M.bovis_AF2122/97           -------------------------------------LAALAVHDAARQA
Rv2974c|M.tuberculosis_H37Rv        -------------------------------------LAALAVHDAARQA
MMAR_1741|M.marinum_M               -------------------------------------LAALAVHDPASQA
MAV_3819|M.avium_104                -------------------------------------LAALAVHDTGRQA
Mflv_4213|M.gilvum_PYR-GCK          -------------------------------------LAALAVHDPGHRL
Mvan_2154|M.vanbaalenii_PYR-1       -------------------------------------LAALAVHDPERRL
MSMEG_2402|M.smegmatis_MC2_155      -------------------------------------LAALAVHDAARQA
TH_0233|M.thermoresistible__bu      -------------------------------------LAALAVHDPGRHA
MAB_3279c|M.abscessus_ATCC_199      -------------------------------------LAALAVHDPERMA
MUL_3169|M.ulcerans_Agy99           SAESGGAGANIASVSTVLFGENNTASASAVGAGNIANVATVLFSDSNTST
                                                                         :*:: . *.    

Mb2999c|M.bovis_AF2122/97           VDDGYSMARAAGASRHGSVRIATQKALTWAG------------------T
Rv2974c|M.tuberculosis_H37Rv        VDDGYSMARAAGASRHGSVRIATQKALTWAG------------------T
MMAR_1741|M.marinum_M               VDDGYIMARAAGAARHGSVRIATETALTWAG------------------T
MAV_3819|M.avium_104                VDDGYTMARAAGAARHGSVRIATETALTWAG------------------S
Mflv_4213|M.gilvum_PYR-GCK          VDDGYTMARAGAAARFGSVRIAAEDALTWAG------------------A
Mvan_2154|M.vanbaalenii_PYR-1       VDDGYTMARAAAGARHGTVRVAAEEALTWAG------------------A
MSMEG_2402|M.smegmatis_MC2_155      VDDGYTMARAAAGARHGSVRVATEEALTWAG------------------A
TH_0233|M.thermoresistible__bu      VDDGYTMAGAAADTRHGSVRVATEQALTWAG------------------P
MAB_3279c|M.abscessus_ATCC_199      VDDSYTMARAAGATRFGLVRVATERALTWSG------------------T
MUL_3169|M.ulcerans_Agy99           VSSFGVENIATVATSYGDFNNVSARTPGIGGNIATFATAFGEGNTNVHAE
                                    *..      *   : .* .. .:  :   .*                   

Mb2999c|M.bovis_AF2122/97           CKPGDG---------------------------------------LGIAG
Rv2974c|M.tuberculosis_H37Rv        CKPGDG---------------------------------------LGIAG
MMAR_1741|M.marinum_M               CKPGDG---------------------------------------LGIAG
MAV_3819|M.avium_104                CRPGDG---------------------------------------LGIAG
Mflv_4213|M.gilvum_PYR-GCK          CRPGDG---------------------------------------LGITG
Mvan_2154|M.vanbaalenii_PYR-1       CKPGDG---------------------------------------LGIAG
MSMEG_2402|M.smegmatis_MC2_155      CKPGDG---------------------------------------LGIAG
TH_0233|M.thermoresistible__bu      CGPGDG---------------------------------------LGIAG
MAB_3279c|M.abscessus_ATCC_199      CEPGDA---------------------------------------MGIIG
MUL_3169|M.ulcerans_Agy99           AGPGGANIATLATVFGDGNAVSVKSIGAGNTASIATMIGNNNTADINVFG
                                    . **..                                       :.: *

Mb2999c|M.bovis_AF2122/97           DEVLIVADDVAAAAIGLVDLLLASGGDLVTVLIGAGVTED----------
Rv2974c|M.tuberculosis_H37Rv        DEVLIVADDVAAAAIGLVDLLLASGGDLVTVLIGAGVTED----------
MMAR_1741|M.marinum_M               DEVLIVADDVAAAAIGLVDLLLAPGGDLVTVLIGAGIDDDE---RIA---
MAV_3819|M.avium_104                GEVLIVAADAVGAAIGLLDLLLASGGDLVTVLLGAGLDADGSDAHAG---
Mflv_4213|M.gilvum_PYR-GCK          DEVVVVGDDIVSAATGLIDLLLAAGGELVTVLTGDGVESE----------
Mvan_2154|M.vanbaalenii_PYR-1       DEVVIVGADVVAAGAGLIDLMLAAGGELVTVLTGDGVGPE----------
MSMEG_2402|M.smegmatis_MC2_155      DEVLIVGPDVTAAAAGLIDLLLAAGGELITVLTGHGVDSA----------
TH_0233|M.thermoresistible__bu      GEVLIVGRDIASAAMGLIDLLLGGGGDLATVLVGEGVDPA----------
MAB_3279c|M.abscessus_ATCC_199      DEVLVLNHDIANATKALVSIMLSSGGELVTVLLSDEVDDS----------
MUL_3169|M.ulcerans_Agy99           LENVATVATAIGDNNGLTANAPGLGANIATVATAIGSGNSQVSAEAGGAG
                                     * :           .*     . *.:: **  .                

Mb2999c|M.bovis_AF2122/97           ------------VAVVLERHVHDHHPGTELVSYRTGHRGDALLIGVE---
Rv2974c|M.tuberculosis_H37Rv        ------------VAVVLERHVHDHHPGTELVSYRTGHRGDALLIGVE---
MMAR_1741|M.marinum_M               -----------RLVESLERHMHDHHPGTELVIYRTGHRGDALLIGVE---
MAV_3819|M.avium_104                -----------AVVDILEEHMHDHHPGTELVTYRTGHHGDVLLIGVE---
Mflv_4213|M.gilvum_PYR-GCK          ------------VGAALAEHVHHNHLGAELVTFHTGHRADALLIGVE---
Mvan_2154|M.vanbaalenii_PYR-1       ------------IGEALAEHVHHHHPGTDLVTFHTGHRVDALVIGVE---
MSMEG_2402|M.smegmatis_MC2_155      ------------VGEALQAHVHDKHLGVELVTYHTGHRGDALLIGVE---
TH_0233|M.thermoresistible__bu      ------------VAERLRDHVHRNHPGTELSVYHTGHRGDALLIGVE---
MAB_3279c|M.abscessus_ATCC_199      ------------LAESLIEHTRSHHGGVEVMIYRTGQHTDVVHIGVE---
MUL_3169|M.ulcerans_Agy99           GNIATLSSVFGDNNTAVVTAFGASNVPTAATVFGSGNGVKVSTFGLENIA
                                                    :       :  .    : :*:  ..  :*:*   

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           TLGTVIGDNNTGVVADAGGVGGNIATLANVFGNDNTAAEATASGVGGNIA
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           TLANVFGDGNAVKANVVGFGNVPSAATVIGSNNTVTTDVFGVENIATLAS
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           VYGDGNSGVLAQSGGVGGNIATLATVIGSNNTATEASAVGIGGNTATLGT
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           ALSDGNAVSATANGFGNTATVATAFIGGGNTATASASGVGNIASLATAVG
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           ADNAVSATASGAGGNIAIAATAIGDGNTEVTADAGGLGGNIGVAATAIGG
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           GNTVAASSTGLTIGSVATAVGDGNTGIAARGHQAGNLGIVSTAIGFGNTD
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           VAAAGFGVANIGNVATVIGSNNQNVFAGGTGLSNIATVGGDNNTALAGDQ
                                                                                      

Mb2999c|M.bovis_AF2122/97           --------------------------------------------------
Rv2974c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1741|M.marinum_M               --------------------------------------------------
MAV_3819|M.avium_104                --------------------------------------------------
Mflv_4213|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2154|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2402|M.smegmatis_MC2_155      --------------------------------------------------
TH_0233|M.thermoresistible__bu      --------------------------------------------------
MAB_3279c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_3169|M.ulcerans_Agy99           SGGLASVNVATVFGSGSGASAFNGFLNLAIGLTDGVMASAGPGNFNVSIH
                                                                                      

Mb2999c|M.bovis_AF2122/97           ----------
Rv2974c|M.tuberculosis_H37Rv        ----------
MMAR_1741|M.marinum_M               ----------
MAV_3819|M.avium_104                ----------
Mflv_4213|M.gilvum_PYR-GCK          ----------
Mvan_2154|M.vanbaalenii_PYR-1       ----------
MSMEG_2402|M.smegmatis_MC2_155      ----------
TH_0233|M.thermoresistible__bu      ----------
MAB_3279c|M.abscessus_ATCC_199      ----------
MUL_3169|M.ulcerans_Agy99           PFFDVQPLFG