For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PQQKSGRGTRPTTDRVREAMFNLLSARIDFSGIRVLDLYAGSGALGLEALSRGARSVLFVESDARAASVI EQNIAALGARGATVRRGSVAAVLSAGAATPVDLVLADPPYEVDAAQVADMVDALDNAGWASPGTVAVVER PASASEIDWPARWSAWKARRYGDTRLEMASVID*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4197 | - | - | 100% (174) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_1039 | - | 8e-06 | 36.14% (83) | putative methylase |
| M. gilvum PYR-GCK | Mflv_2308 | - | 8e-05 | 30.22% (139) | HemK family modification methylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2990c | - | 2e-57 | 65.64% (163) | methyltransferase (methylase) |
| M. tuberculosis H37Rv | Rv2966c | - | 2e-57 | 65.64% (163) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_01664 | - | 2e-51 | 60.26% (156) | hypothetical protein MLBr_01664 |
| M. abscessus ATCC 19977 | MAB_3266c | - | 6e-34 | 51.01% (149) | hypothetical protein MAB_3266c |
| M. marinum M | MMAR_1750 | - | 5e-52 | 62.34% (154) | methyltransferase |
| M. avium 104 | MAV_3811 | - | 2e-57 | 65.64% (163) | putative methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2413 | - | 2e-56 | 65.24% (164) | putative methyltransferase |
| M. thermoresistible (build 8) | TH_1228 | - | 5e-50 | 62.34% (154) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2166 | - | 2e-72 | 77.33% (172) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4197|M.gilvum_PYR-GCK -----------MPQQKSGRGTRPTTDRVREAMFNLLSARIDFSGIRVLDL
Mvan_2166|M.vanbaalenii_PYR-1 -----------MPQQKSGRGTRPTTDRVRESLFNVLTARIDFTGIRVLDL
Mb2990c|M.bovis_AF2122/97 MTRIIGGVAGGRRIAVPPRGTRPTTDRVRESLFNIVTARRDLTGLAVLDL
Rv2966c|M.tuberculosis_H37Rv MTRIIGGVAGGRRIAVPPRGTRPTTDRVRESLFNIVTARRDLTGLAVLDL
MMAR_1750|M.marinum_M ---------------------------MRESLFNILAARRAMTGLAVLDL
MAV_3811|M.avium_104 MTRIIGGVAGGRRLAVPPRGTRPTTDRVRESLFNILAARRELTGLAVLDL
MLBr_01664|M.leprae_Br4923 ---------------------------MRESLFNIVAAQRELTGLAVLDL
TH_1228|M.thermoresistible__bu ---------------------------VREALFNLLTARMELAGATVLDL
MSMEG_2413|M.smegmatis_MC2_155 ---------------MPKSGTRPTSDRVREAVFNALAARLDFAGLAVLDL
MAB_3266c|M.abscessus_ATCC_199 ----------------------------------MLEARLDFEGIAVLDL
: *: : * ****
Mflv_4197|M.gilvum_PYR-GCK YAGSGALGLEALSRGARSVLFVESDARAASVIEQNIAALGARGATVRRGS
Mvan_2166|M.vanbaalenii_PYR-1 YAGSGALGLEALSRGAASAVFVESDGRAAAVIEQNIAALGARGAAVRRGP
Mb2990c|M.bovis_AF2122/97 YAGSGALGLEALSRGAASVLFVESDQRSAAVIARNIEALGLSGATLRRGA
Rv2966c|M.tuberculosis_H37Rv YAGSGALGLEALSRGAASVLFVESDQRSAAVIARNIEALGLSGATLRRGA
MMAR_1750|M.marinum_M YAGSGALGLEALSRGAAAALFVESDQRTAAVLARNIEALGLAGATLRRGA
MAV_3811|M.avium_104 YAGSGALGLEALSRGAATALFVESDPRAAAVIARNIDTLGLPGATLRRGA
MLBr_01664|M.leprae_Br4923 YAGSGALGLEALSRGAASTLFVESDKRTVAVIERNVTALGLVGARPRCGP
TH_1228|M.thermoresistible__bu YAGSGALGLEAMSRGAASVVFVESDHRAAAIIAKNIATLGVRDAEVRRTS
MSMEG_2413|M.smegmatis_MC2_155 YAGSGALGLEAISRGASSALFVESDQRAAAVIAKNIAALDVAGATVRRGT
MAB_3266c|M.abscessus_ATCC_199 FAGSGALGLEALSRGAQHVTFVESNAAASRVISANIATVGLPGAVLRQCP
:**********:**** . ****: : :: *: ::. .* * .
Mflv_4197|M.gilvum_PYR-GCK VAAVLSAGAATPVDLVLADPPYEVDAAQVADMVDALDNAGWASPGTVAVV
Mvan_2166|M.vanbaalenii_PYR-1 VSSVLAGGADRPVDLVLADPPYEVDDAQVNEIVTALSSGRWVAPGTVVVV
Mb2990c|M.bovis_AF2122/97 VAAVVAAGTTSPVDLVLADPPYNVDSADVDAILAALGTNGWTREGTVAVV
Rv2966c|M.tuberculosis_H37Rv VAAVVAAGTTSPVDLVLADPPYNVDSADVDAILAALGTNGWTREGTVAVV
MMAR_1750|M.marinum_M VAAVLAGGTASPFDLILADPPYDVSCAEIEAVLAALDSHGWVHQATVAVV
MAV_3811|M.avium_104 VAAVLAGGTATAVDLVLADPPYDVGAAEIDAVLAALAAHGWVRAGSVAVM
MLBr_01664|M.leprae_Br4923 VATVLAAGTASPMDLVLADPPYAIDTAEVEAVLATLTTYGWARPGTVAVI
TH_1228|M.thermoresistible__bu VASVLTAGADGPVDLVLADPPYRVTNDEMHALLATLVDRGWTAPGTVVAV
MSMEG_2413|M.smegmatis_MC2_155 AESVLAAGTTRPVDLVLADPPYDVDARTVDALVVALADGGWVRAGTVVMV
MAB_3266c|M.abscessus_ATCC_199 VSTFLSMSPDRAYDLVLADPPYSVSAEEVSALLSRLTDH-WVTDEALVVL
. :.:: .. . **:****** : : :: * *. ::. :
Mflv_4197|M.gilvum_PYR-GCK ERPASASEIDWPARWSAWKARRYGDTRLEMASVID----
Mvan_2166|M.vanbaalenii_PYR-1 ERPASGPGIAWPEGWSVWKSRRYGDTRLEMAAVDR----
Mb2990c|M.bovis_AF2122/97 ERATTCAPLTWPEGWRRWPQRVYGDTRLELAERLFANV-
Rv2966c|M.tuberculosis_H37Rv ERATTCAPLTWPEGWRRWPQRVYGDTRLELAERLFANV-
MMAR_1750|M.marinum_M ERPATGAALTWPAGWSVWPERVYGDTRLELADRS-----
MAV_3811|M.avium_104 ERPAGSAPLSWPAGWSGWPHRVYGDTRLELAERL-----
MLBr_01664|M.leprae_Br4923 ERGAASVPLTWPAGWSSWQSRGYGDTRLELAELT-----
TH_1228|M.thermoresistible__bu ERGTGHDPLRWPAGWTVWPPRRYGDTRLELARAEPDRPR
MSMEG_2413|M.smegmatis_MC2_155 ERRFNSDLVTWPDGWTALSARRYGDTRVELAEVG-----
MAB_3266c|M.abscessus_ATCC_199 ERDASGPEAVWPDGWELMS-RKYGGTRLELGSL------
** ** * * **.**:*:.