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VPKSGTRPTSDRVREAVFNALAARLDFAGLAVLDLYAGSGALGLEAISRGASSALFVESDQRAAAVIAKN IAALDVAGATVRRGTAESVLAAGTTRPVDLVLADPPYDVDARTVDALVVALADGGWVRAGTVVMVERRFN SDLVTWPDGWTALSARRYGDTRVELAEVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2413 | - | - | 100% (169) | putative methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1771 | - | 9e-06 | 33.33% (114) | methylase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2990c | - | 1e-59 | 66.47% (167) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_4197 | - | 2e-56 | 65.24% (164) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv2966c | - | 1e-59 | 66.47% (167) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_01664 | - | 5e-48 | 58.33% (156) | hypothetical protein MLBr_01664 |
| M. abscessus ATCC 19977 | MAB_3266c | - | 7e-34 | 50.68% (148) | hypothetical protein MAB_3266c |
| M. marinum M | MMAR_1750 | - | 4e-50 | 61.94% (155) | methyltransferase |
| M. avium 104 | MAV_3811 | - | 3e-57 | 65.87% (167) | putative methyltransferase |
| M. thermoresistible (build 8) | TH_1228 | - | 1e-48 | 63.64% (154) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_4684 | - | 8e-05 | 26.88% (160) | hypothetical protein MUL_4684 |
| M. vanbaalenii PYR-1 | Mvan_2166 | - | 5e-58 | 65.85% (164) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2990c|M.bovis_AF2122/97 MTRIIGGVAGGRRIAVPPRGTRPTTDRVRESLFNIVTARRDLTGLAVLDL
Rv2966c|M.tuberculosis_H37Rv MTRIIGGVAGGRRIAVPPRGTRPTTDRVRESLFNIVTARRDLTGLAVLDL
MMAR_1750|M.marinum_M ---------------------------MRESLFNILAARRAMTGLAVLDL
MAV_3811|M.avium_104 MTRIIGGVAGGRRLAVPPRGTRPTTDRVRESLFNILAARRELTGLAVLDL
MLBr_01664|M.leprae_Br4923 ---------------------------MRESLFNIVAAQRELTGLAVLDL
TH_1228|M.thermoresistible__bu ---------------------------VREALFNLLTARMELAGATVLDL
Mflv_4197|M.gilvum_PYR-GCK -----------MPQQKSGRGTRPTTDRVREAMFNLLSARIDFSGIRVLDL
Mvan_2166|M.vanbaalenii_PYR-1 -----------MPQQKSGRGTRPTTDRVRESLFNVLTARIDFTGIRVLDL
MSMEG_2413|M.smegmatis_MC2_155 ---------------MPKSGTRPTSDRVREAVFNALAARLDFAGLAVLDL
MAB_3266c|M.abscessus_ATCC_199 ----------------------------------MLEARLDFEGIAVLDL
MUL_4684|M.ulcerans_Agy99 -----MGRVALTESEEYARQYFDEQAESNNEYWRRFGVVPDWAGKRVLDV
. . * ***:
Mb2990c|M.bovis_AF2122/97 YAGSGALGLEALSRGAASVLFVESDQRSAAVIARNIEALGLSGATLRRGA
Rv2966c|M.tuberculosis_H37Rv YAGSGALGLEALSRGAASVLFVESDQRSAAVIARNIEALGLSGATLRRGA
MMAR_1750|M.marinum_M YAGSGALGLEALSRGAAAALFVESDQRTAAVLARNIEALGLAGATLRRGA
MAV_3811|M.avium_104 YAGSGALGLEALSRGAATALFVESDPRAAAVIARNIDTLGLPGATLRRGA
MLBr_01664|M.leprae_Br4923 YAGSGALGLEALSRGAASTLFVESDKRTVAVIERNVTALGLVGARPRCGP
TH_1228|M.thermoresistible__bu YAGSGALGLEAMSRGAASVVFVESDHRAAAIIAKNIATLGVRDAEVRRTS
Mflv_4197|M.gilvum_PYR-GCK YAGSGALGLEALSRGARSVLFVESDARAASVIEQNIAALGARGATVRRGS
Mvan_2166|M.vanbaalenii_PYR-1 YAGSGALGLEALSRGAASAVFVESDGRAAAVIEQNIAALGARGAAVRRGP
MSMEG_2413|M.smegmatis_MC2_155 YAGSGALGLEAISRGASSALFVESDQRAAAVIAKNIAALDVAGATVRRGT
MAB_3266c|M.abscessus_ATCC_199 FAGSGALGLEALSRGAQHVTFVESNAAASRVISANIATVGLPGAVLRQCP
MUL_4684|M.ulcerans_Agy99 GCGHGALSIDIAQAGAS-VLGVDLDEGRVAFANRNLAQRFPEQADRVRFR
.* ***.:: . ** . *: : . *: *
Mb2990c|M.bovis_AF2122/97 VAAVVAAGTTSPVDLVLADPPYNVDSADVDAILAALGTNGWTREGTVAV-
Rv2966c|M.tuberculosis_H37Rv VAAVVAAGTTSPVDLVLADPPYNVDSADVDAILAALGTNGWTREGTVAV-
MMAR_1750|M.marinum_M VAAVLAGGTASPFDLILADPPYDVSCAEIEAVLAALDSHGWVHQATVAV-
MAV_3811|M.avium_104 VAAVLAGGTATAVDLVLADPPYDVGAAEIDAVLAALAAHGWVRAGSVAV-
MLBr_01664|M.leprae_Br4923 VATVLAAGTASPMDLVLADPPYAIDTAEVEAVLATLTTYGWARPGTVAV-
TH_1228|M.thermoresistible__bu VASVLTAGADGPVDLVLADPPYRVTNDEMHALLATLVDRGWTAPGTVVA-
Mflv_4197|M.gilvum_PYR-GCK VAAVLSAGAATPVDLVLADPPYEVDAAQVADMVDALDNAGWASPGTVAV-
Mvan_2166|M.vanbaalenii_PYR-1 VSSVLAGGADRPVDLVLADPPYEVDDAQVNEIVTALSSGRWVAPGTVVV-
MSMEG_2413|M.smegmatis_MC2_155 AESVLAAGTTRPVDLVLADPPYDVDARTVDALVVALADGGWVRAGTVVM-
MAB_3266c|M.abscessus_ATCC_199 VSTFLSMSPDRAYDLVLADPPYSVSAEEVSALLSRLTDH-WVTDEALVV-
MUL_4684|M.ulcerans_Agy99 AVDVRSLPVDEPFDVIVSKDTFEH-VADVASLLLALGERLTRPGGRIYAG
. . : . *::::. .: : :: * :
Mb2990c|M.bovis_AF2122/97 ---------VERATTCAPLTWPEGWR------RWPQRVYGDTRLELAERL
Rv2966c|M.tuberculosis_H37Rv ---------VERATTCAPLTWPEGWR------RWPQRVYGDTRLELAERL
MMAR_1750|M.marinum_M ---------VERPATGAALTWPAGWS------VWPERVYGDTRLELADRS
MAV_3811|M.avium_104 ---------MERPAGSAPLSWPAGWS------GWPHRVYGDTRLELAERL
MLBr_01664|M.leprae_Br4923 ---------IERGAASVPLTWPAGWS------SWQSRGYGDTRLELAELT
TH_1228|M.thermoresistible__bu ---------VERGTGHDPLRWPAGWT------VWPPRRYGDTRLELARAE
Mflv_4197|M.gilvum_PYR-GCK ---------VERPASASEIDWPARWS------AWKARRYGDTRLEMASVI
Mvan_2166|M.vanbaalenii_PYR-1 ---------VERPASGPGIAWPEGWS------VWKSRRYGDTRLEMAAVD
MSMEG_2413|M.smegmatis_MC2_155 ---------VERRFNSDLVTWPDGWT------ALSARRYGDTRVELAEVG
MAB_3266c|M.abscessus_ATCC_199 ---------LERDASGPEAVWPDGWE------LMS-RKYGGTRLELGSL-
MUL_4684|M.ulcerans_Agy99 FSPLYYSPFGDHGRTGLKVPWTHAILPKRLVFAVAARKYGHPVGSLLDIG
:: *. * ** . .:
Mb2990c|M.bovis_AF2122/97 FANV----------------------------------------------
Rv2966c|M.tuberculosis_H37Rv FANV----------------------------------------------
MMAR_1750|M.marinum_M --------------------------------------------------
MAV_3811|M.avium_104 --------------------------------------------------
MLBr_01664|M.leprae_Br4923 --------------------------------------------------
TH_1228|M.thermoresistible__bu PDRPR---------------------------------------------
Mflv_4197|M.gilvum_PYR-GCK D-------------------------------------------------
Mvan_2166|M.vanbaalenii_PYR-1 R-------------------------------------------------
MSMEG_2413|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3266c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4684|M.ulcerans_Agy99 LNGNTPDQFRAAFDNSGLRQLDIGYNRGAKRLLPALERARRHWRRFDRFT
Mb2990c|M.bovis_AF2122/97 ----------
Rv2966c|M.tuberculosis_H37Rv ----------
MMAR_1750|M.marinum_M ----------
MAV_3811|M.avium_104 ----------
MLBr_01664|M.leprae_Br4923 ----------
TH_1228|M.thermoresistible__bu ----------
Mflv_4197|M.gilvum_PYR-GCK ----------
Mvan_2166|M.vanbaalenii_PYR-1 ----------
MSMEG_2413|M.smegmatis_MC2_155 ----------
MAB_3266c|M.abscessus_ATCC_199 ----------
MUL_4684|M.ulcerans_Agy99 TVSIYAVFGV