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MPVPQRNSPQKPQADVRNGRRPRGEARRLLLDAARELFARKDYRATTTREIAEAAGVSEYLLFRHFGSKA GLFREALVVPFTSFLDQFRSTWQSVIPEETDEEELSRQFVGQLYDVLVDHRGLLLTLVAADGLSAEDIEA AGIADIRRSLRVLGQISAEGMQLRGLHSEQPDLPAHSTVATIVGMVAMRSTFFGENPPSREIIVDELVQA VLHGFLHRPDREPLSPKSVRPLQQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4147 | - | - | 100% (234) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 1e-09 | 27.14% (210) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 4e-08 | 30.88% (136) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1047 | - | 9e-09 | 26.67% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1019 | - | 9e-09 | 26.67% (195) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-06 | 25.71% (210) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 6e-14 | 28.70% (223) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4466 | - | 4e-10 | 26.54% (211) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2137 | - | 2e-55 | 68.79% (141) | hypothetical protein MAV_2137 |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 1e-10 | 27.60% (221) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 1e-12 | 29.86% (211) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4635 | - | 1e-09 | 26.67% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1795 | - | 9e-10 | 27.14% (210) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4466|M.marinum_M ----------------------MPEKEAKAPRARMTGSERRHQLIGIARS
MUL_4635|M.ulcerans_Agy99 ----------------------------------MTGSERRHQLIGIARS
Mb1047|M.bovis_AF2122/97 ----------------------------------MTGTERRHQLIGIARS
Rv1019|M.tuberculosis_H37Rv ----------------------------------MTGTERRHQLIGIARS
MAB_1149|M.abscessus_ATCC_1997 -----------------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVARS
MSMEG_1935|M.smegmatis_MC2_155 MSDLANTAERRGEK---------RPAGGNRRGNRLPRDERRGQLLIAASE
Mvan_1795|M.vanbaalenii_PYR-1 MSEVARTAQRRGGQPANG----ASPSGAARRGNRMPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mflv_4147|M.gilvum_PYR-GCK --------------MPVPQRNSPQKPQADVRNGRRPRGEARRLLLDAARE
MAV_2137|M.avium_104 --------------------------------------------------
MMAR_4466|M.marinum_M LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGKEGLY----AVVVDREMS
MUL_4635|M.ulcerans_Agy99 LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGKEGLY----AVVVDREMS
Mb1047|M.bovis_AF2122/97 LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGKEGLY----AVVVDREMS
Rv1019|M.tuberculosis_H37Rv LFAERGYDGTSIEEIAQRANVSKPVVYEHFGGKEGLY----AVVVDREMS
MAB_1149|M.abscessus_ATCC_1997 LFAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLY----AVVVDREMS
MSMEG_1935|M.smegmatis_MC2_155 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELY----LAVLQRHVD
Mvan_1795|M.vanbaalenii_PYR-1 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELY----LAVLQRHVD
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELY----LAVLQRHVD
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELY----LAVLERHMN
Mflv_4147|M.gilvum_PYR-GCK LFARKDYRATTTREIAEAAGVSEYLLFRHFGSKAGLFREALVVPFTSFLD
MAV_2137|M.avium_104 -----------------------------------------MLPFTDFVD
. :.
MMAR_4466|M.marinum_M ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
MUL_4635|M.ulcerans_Agy99 ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
Mb1047|M.bovis_AF2122/97 ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
Rv1019|M.tuberculosis_H37Rv ALLDGITSSLTNNR-SRVRVERVALALLTYVEERTDGFRIMIRDSPASIS
MAB_1149|M.abscessus_ATCC_1997 VLLDGITSSLTSYR-SRVRLEQVALALLSYIEERTDGFRILIRDSPPGVS
MSMEG_1935|M.smegmatis_MC2_155 NLVSGVRQALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFEND-YVTE
Mvan_1795|M.vanbaalenii_PYR-1 NLVSGVRQALRTTTDNRQRVRAAVQAFFDFIEHDGQGYRLIFEND-YVTE
TH_0452|M.thermoresistible__bu NLVSGVRQALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFEND-YVTE
MLBr_00815|M.leprae_Br4923 NLVSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEND-NITE
Mflv_4147|M.gilvum_PYR-GCK QFRSTWQSVIPEETDEEELSRQFVGQLYDVLVDHRGLLLTLVAADGLSAE
MAV_2137|M.avium_104 EFGRTWQAVVPEQTDEEELARRFVGQLYDVFVEHQGLLLTLMASEALSEE
: : .. . . : . . :. . .
MMAR_4466|M.marinum_M SGTYSSLLND--AVSQVSSILAGDFARRGLDSELAPLYAQALVGSVS--M
MUL_4635|M.ulcerans_Agy99 SGTYSSLLND--AVSQVSSILAGDFARRGLDSELAPLYAQALVGSVS--M
Mb1047|M.bovis_AF2122/97 SGTYSSLLND--AVSQVSSILAGDFARRGLDPDLAPLYAQALVGSVS--M
Rv1019|M.tuberculosis_H37Rv SGTYSSLLND--AVSQVSSILAGDFARRGLDPDLAPLYAQALVGSVS--M
MAB_1149|M.abscessus_ATCC_1997 SGTYSSLLND--AVSQVSSILAGDFQRRGLDAEMAPLYAQALVGQVS--M
MSMEG_1935|M.smegmatis_MC2_155 PQVAAQVKVA--TEACTDAVFDLISRDSGLEAHRARMIAVGLVAISV--D
Mvan_1795|M.vanbaalenii_PYR-1 PQVAAQVKVA--TESCTDAVFDLISHDSGLEPHRARMIAVGLVSISV--D
TH_0452|M.thermoresistible__bu PQVAAQVKVA--TEACTDAVFDLISQDSGLEAHRARMIAVGLVAISV--D
MLBr_00815|M.leprae_Br4923 PRVAAQVRVA--TESCIDAVFALISADSRLDPHRARMVAVGLVGISV--D
Mflv_4147|M.gilvum_PYR-GCK DIEAAGIADIRRSLRVLGQISAEGMQLRGLHSEQPDLPAHSTVATIVGMV
MAV_2137|M.avium_104 EKADAGIAEVRRAITTLGRISAEGMHLRGLRSDHPDLPAHSTVAMIAGMA
: : : . : * .. . : * . *.
MMAR_4466|M.marinum_M TAQWWLDAREPK-KEVVAAHLVNLVWNGLTHLEADPQLQDE-------
MUL_4635|M.ulcerans_Agy99 TAQWWLDAREPK-KEVVAAHLVNLVWNGLTHLEADPQLQDE-------
Mb1047|M.bovis_AF2122/97 TAQWWLDAREPK-KEVVAAHLVNLVWNGLTHLEADPRLQDE-------
Rv1019|M.tuberculosis_H37Rv TAQWWLDAREPK-KEVVAAHLVNLVWNGLTHLEADPRLQDE-------
MAB_1149|M.abscessus_ATCC_1997 TAQWWLDAREPK-KEVVAAHIVNLCWHGLKHLEADPQLHEE-------
MSMEG_1935|M.smegmatis_MC2_155 SARYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS-----------
Mvan_1795|M.vanbaalenii_PYR-1 SARYWLNNDRPIDKDDAVEGTVQFIWGGLSHVPMTRS-----------
TH_0452|M.thermoresistible__bu CARYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS-----------
MLBr_00815|M.leprae_Br4923 CARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-----------
Mflv_4147|M.gilvum_PYR-GCK AMRSTFFGENPPSREIIVDELVQAVLHGFLHRPDREPLSPKSVRPLQQ
MAV_2137|M.avium_104 ALRSTYFGAEPPSREVIVDELIQAILHGFLHRNG--------------
: .* :. . :: *: *