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SRLLELLEVTQAQPPTWRGPASGPQGKRAYGGQLAAQSLAAAARTVDRSKAPTAMHLQFLRGGVAGDPTD YAVVNVHDGRTAASRRVDATQGERLLTTSTVSFAVALPGPEHGRRELPAEDPESLPQTGPPGPAPSLPLD ELDLRYVDDGSGEGFVRRLWWRTVVDLPEDPLLHTLIAVYVTDVYLIDPALQVHGHSMRARTHRSGTTDS SIWFHHEVRAGEWNLLECRSPAAARGRGVVTANLIRRDGVLAATLVQEGLIADREPAPPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4143 | - | - | 100% (271) | acyl-CoA thioesterase |
| M. gilvum PYR-GCK | Mflv_3590 | - | 1e-32 | 30.99% (284) | acyl-CoA thioesterase |
| M. gilvum PYR-GCK | Mflv_3831 | - | 5e-28 | 30.86% (269) | acyl-CoA thioesterase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1644 | tesB1 | 3e-33 | 30.66% (274) | acyl-CoA thioesterase II TesB1 |
| M. tuberculosis H37Rv | Rv1618 | tesB1 | 2e-33 | 30.66% (274) | acyl-CoA thioesterase II TesB1 |
| M. leprae Br4923 | MLBr_01278 | tesB | 5e-33 | 32.85% (274) | acyl CoA thioesterase II |
| M. abscessus ATCC 19977 | MAB_2638c | - | 1e-34 | 34.27% (248) | acyl-CoA thioesterase |
| M. marinum M | MMAR_2421 | tesB1 | 6e-35 | 32.48% (274) | acyl-CoA thioesterase II TesB1 |
| M. avium 104 | MAV_3169 | - | 8e-33 | 32.12% (274) | Acyl-CoA thioesterase |
| M. smegmatis MC2 155 | MSMEG_2470 | - | 1e-100 | 66.04% (265) | acyl-CoA thioesterase |
| M. thermoresistible (build 8) | TH_3637 | - | 1e-105 | 73.12% (253) | PUTATIVE acyl-CoA thioesterase |
| M. ulcerans Agy99 | MUL_1599 | tesB1 | 9e-35 | 32.48% (274) | acyl-CoA thioesterase II TesB1 |
| M. vanbaalenii PYR-1 | Mvan_2198 | - | 1e-126 | 81.72% (268) | acyl-CoA thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2421|M.marinum_M MPAGDEPNVRDEAKSDFEELLAVLDLKRVA-DDRFIGAHPSKNPMRTFGG
MUL_1599|M.ulcerans_Agy99 --------MRDEAKSDFEELLAVLDLKRVA-DDRFIGAHPSKNPMRTFGG
MAV_3169|M.avium_104 MPAGAE-SQEPNTTADFEELLATLDLRRVA-DDLFVGSHPSKNPMRTFGG
Mb1644|M.bovis_AF2122/97 -------MPDGKPMSDFDELLAVLDLNAVA-SDLFTGSHPSKNPLRTFGG
Rv1618|M.tuberculosis_H37Rv -------MPDGKPMSDFDELLAVLDLNAVA-SDLFTGSHPSKNPLRTFGG
MLBr_01278|M.leprae_Br4923 ----MKRLWEKKTMSDFEELLAVLDLNRVA-DDLFIGSHPSKNPLRTFGG
MAB_2638c|M.abscessus_ATCC_199 ---------------------------------MFVGGHPTVNPPRTFGG
Mflv_4143|M.gilvum_PYR-GCK ----------------MSRLLELLEVTQAQ-PPTWRGPASGPQGKRAYGG
Mvan_2198|M.vanbaalenii_PYR-1 ----------------MSTLLGLLDVTGAG-PQSWRGRAGGPAGKRAYGG
TH_3637|M.thermoresistible__bu ------------------------VAAGDG-ADQWIGAASGPAGKRAYGG
MSMEG_2470|M.smegmatis_MC2_155 ----------------MSELPRLLDLDEHDDEDTWTGPASGPDGKRAFGG
: * *::**
MMAR_2421|M.marinum_M LLMAQSFVASSRTLLRDDLPPSALSVHFINGGDTTKDIEFQVVRLRDERR
MUL_1599|M.ulcerans_Agy99 LLMAQSFVANSRTLLRDDLPPSALSVHFINGGDTTKDIEFQVVRLRDERR
MAV_3169|M.avium_104 QLMSQSFVASSRSLIRDDLPPSALSVHFINGGDTGKDIEYRVTRLRDERR
Mb1644|M.bovis_AF2122/97 QLMAQSFVASSRTLTRHHLPPSAFSVHFINGGDTAKDIEFQVIRLRDERR
Rv1618|M.tuberculosis_H37Rv QLMAQSFVASSRTLTRHHLPPSAFSVHFINGGDTAKDIEFQVIRLRDERR
MLBr_01278|M.leprae_Br4923 QLVAQSFVASSRTLIRDDLPPSAFSVHFINGGDTAKEIEFHVVRLRDERR
MAB_2638c|M.abscessus_ATCC_199 QLMAQSLVASGRTVS-EKLSLAAISTHFVNGGDPELDIEFRVQRLRDERN
Mflv_4143|M.gilvum_PYR-GCK QLAAQSLAAAARTVDRSKAP-TAMHLQFLRGGVAGDPTDYAVVNVHDGRT
Mvan_2198|M.vanbaalenii_PYR-1 QLAAQSLAAAARTVDPAKAP-TAMHLQFLRGGEAGDPVDYRVEQIYDGRT
TH_3637|M.thermoresistible__bu QLVAQSLAAAARTVPAERPP-TSLHLQFLRGGDAGAPVEYTVTGLLDGRT
MSMEG_2470|M.smegmatis_MC2_155 LRAAQSLAAAARTVGDDRAP-TNMHMQFLRGGDAGEPARYRVHRVYDGRT
:**:.* .*:: . : : :*:.** . : * : * *
MMAR_2421|M.marinum_M FANRRIDAVQNGTLLSSAMISYMSGGRGLEHGVEPPPVADPETRPPIGEL
MUL_1599|M.ulcerans_Agy99 FANRRIDAVQNGTLLSSAMISYMSGGRGLEHGVEPPPVADPETRPPIGEL
MAV_3169|M.avium_104 FANRRVDAVQDGTLLCSALISYMAGGRGLEHGVDPPRVADPETQPTIVEL
Mb1644|M.bovis_AF2122/97 FANRRVDAVQDGTLLSSAMVSYMAGGRGLEHALDPPQVAEPHTRPPIGEL
Rv1618|M.tuberculosis_H37Rv FANRRVDAVQDGTLLSSAMVSYMAGGRGHEHALDPPQVAEPHTRPPIGEL
MLBr_01278|M.leprae_Br4923 FANRRVDAIQDGMLLSSAMASYMSGGCGLEHAVEPPEAAEPHTRPPIGEL
MAB_2638c|M.abscessus_ATCC_199 FANRRVDAVQGDLLLSSALVSYLKDSPGLEHAVNPPVVADPETLPSIDEH
Mflv_4143|M.gilvum_PYR-GCK AASRRVDATQGERLLTTSTVSFAVALPGPEHGRRELPAEDPESLPQTGPP
Mvan_2198|M.vanbaalenii_PYR-1 AASRRVDSTQNGRLLTTATVSFAAALPGPEHGQRDLGGADPESLPRTGPA
TH_3637|M.thermoresistible__bu TAARRVDARQDGRLLTTATVSFAVPLSGPRHGWRTELPGDPEQLPRTGPA
MSMEG_2470|M.smegmatis_MC2_155 ASARRVDAHEHGRLLTTATVSFATPLPGPEHGRRTSVPHDPEALPRTGPP
: **:*: : ** :: *: * .*. :*. *
MMAR_2421|M.marinum_M LRGYEETVPHFVNALQPIEWRYTNDPSWVMRDKGERLHYNRVWVKALGKL
MUL_1599|M.ulcerans_Agy99 LRGYEETVPHFVNALQPIEWRYTNDPSWVMRDKGERLHYNRVWVKALGKL
MAV_3169|M.avium_104 LRGYEETVPHFVNALQPIEWRYTNDPAWVMRTKGERLPHNRVWVKALGKL
Mb1644|M.bovis_AF2122/97 LRGYEETVPHFVNALQPIEWRYANDPAWIMRDKGDRLAYNRVWVKALGEM
Rv1618|M.tuberculosis_H37Rv LRGYEETVPHFVNALQPIEWRYANDPAWIMRDKGDRLAYNRVWVKALGEM
MLBr_01278|M.leprae_Br4923 LRGYEQIVQHFVNALQPVEWRYVNDPSWVMRNKGQRLAYNRVWVKALGAL
MAB_2638c|M.abscessus_ATCC_199 LVGYEETVPMFVAALKPIEWRYDNDPAWVLKAKSQRLEHNRVWMKTHAAL
Mflv_4143|M.gilvum_PYR-GCK G-------PAPSLPLDELDLRYVDD------GSGEGFVR-RLWWRTVVDL
Mvan_2198|M.vanbaalenii_PYR-1 G-------PAPSMPLHELDLRLVDD------GHGEEFVR-RLWWRATVDL
TH_3637|M.thermoresistible__bu G-------PAPSMPLDELDIRIADE------GGGAGFVR-RFWWRATVAL
MSMEG_2470|M.smegmatis_MC2_155 G-------PAPSLPLDEFDIRIADD------TAGGGFTR-RFWWRVTTAL
.*. .: * :: . : *.* :. :
MMAR_2421|M.marinum_M PDDPILHTATMLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
MUL_1599|M.ulcerans_Agy99 PDDPILHTATMLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
MAV_3169|M.avium_104 PDDPVLHTAAMVYSSDTTVLDSVITTHGLSWGFDRIFAASANHSIWFHRQ
Mb1644|M.bovis_AF2122/97 PDDPVLHTATLLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
Rv1618|M.tuberculosis_H37Rv PDDPVLHTATLLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
MLBr_01278|M.leprae_Br4923 PNDPTLHTAAMLYSTDTTVLDSVITTHGLSWGFDRIFAVSANHSVWFHRQ
MAB_2638c|M.abscessus_ATCC_199 PDDPVLHSAALVYSSDTTILDSIITTHGLSWGYDRIFAATINHSVWFHRP
Mflv_4143|M.gilvum_PYR-GCK PEDPLLHTLIAVYVTDVYLIDPALQVHGHSMRARTHRSGTTDSSIWFHHE
Mvan_2198|M.vanbaalenii_PYR-1 PDDPLLHTLIAVYVTDVYLIDPALQVHGHSMRSRTHRSGTTDSSVWFHRE
TH_3637|M.thermoresistible__bu PDDPLVHTLVAAYVTDVYLIDPALQVHGFSMRARTHRSGTTDSSLWFHRR
MSMEG_2470|M.smegmatis_MC2_155 PDDALLHTMVALYITDLYGIDPALGVHGLTMRSRSHRSGTTDSSMWFHRR
*:*. :*: * :* :*. : .** : : : : *:***:
MMAR_2421|M.marinum_M VDFNDWVLYSTSSPVAADSRGLGTGHFFNRTGQPVATVVQEGVLKYFPAA
MUL_1599|M.ulcerans_Agy99 VDFNDWVLYSTSSPVAADSRGLGTGHFFNRTGQPVATVVQEGVLKYFPAA
MAV_3169|M.avium_104 VDFNDWVLYSTSSPVAADSRGLGTGHFFDRSGQPLATVMQEGVLKYFPSA
Mb1644|M.bovis_AF2122/97 VNFDDWVLYSTSSPVAADSRGLGSGHFFDRSGKLIATVVQEGVLKYFPAT
Rv1618|M.tuberculosis_H37Rv VNFDDWVLYSTSSPVAADSRGLGSGHFFDRSGKLIATVVQEGVLKYFPAT
MLBr_01278|M.leprae_Br4923 VNFDDWVLYSTSSPVAADSRGLGTGHLFDRSGQLIATVVQEGVLKYFPAS
MAB_2638c|M.abscessus_ATCC_199 LRFDDWVLYATESPVASAGRGMGAGRYFDRDGALLASTIQEGIVKYFPGR
Mflv_4143|M.gilvum_PYR-GCK VRAGEWNLLECRSPAAARGRGVVTANLIRRDGVLAATLVQEGLIADREPA
Mvan_2198|M.vanbaalenii_PYR-1 VRADQWNLLECRSPAAARGRGVVTACLIRSDGVLAATLVQEGLVAEREPA
TH_3637|M.thermoresistible__bu IRADEWNLLECTSPAAGRGRAVVNASLIRADGVIAATLAQEGLIADRGQP
MSMEG_2470|M.smegmatis_MC2_155 VRADEWNLLEQTSPAAARGRGIITSSLVQLDGSVVATLVQEGLMAERTTD
: .:* * **.*. .*.: . . * *: ***::
MMAR_2421|M.marinum_M RR------
MUL_1599|M.ulcerans_Agy99 RR------
MAV_3169|M.avium_104 RR------
Mb1644|M.bovis_AF2122/97 PDSAAGRS
Rv1618|M.tuberculosis_H37Rv PDSAAGRS
MLBr_01278|M.leprae_Br4923 HR------
MAB_2638c|M.abscessus_ATCC_199 S-------
Mflv_4143|M.gilvum_PYR-GCK P-PA----
Mvan_2198|M.vanbaalenii_PYR-1 THPAG---
TH_3637|M.thermoresistible__bu PR------
MSMEG_2470|M.smegmatis_MC2_155 --------