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VSELPRLLDLDEHDDEDTWTGPASGPDGKRAFGGLRAAQSLAAAARTVGDDRAPTNMHMQFLRGGDAGEP ARYRVHRVYDGRTASARRVDAHEHGRLLTTATVSFATPLPGPEHGRRTSVPHDPEALPRTGPPGPAPSLP LDEFDIRIADDTAGGGFTRRFWWRVTTALPDDALLHTMVALYITDLYGIDPALGVHGLTMRSRSHRSGTT DSSMWFHRRVRADEWNLLEQTSPAAARGRGIITSSLVQLDGSVVATLVQEGLMAERTTD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2470 | - | - | 100% (269) | acyl-CoA thioesterase |
| M. smegmatis MC2 155 | MSMEG_3228 | - | 2e-32 | 32.36% (275) | acyl-CoA thioesterase II |
| M. smegmatis MC2 155 | MSMEG_2938 | tesB | 6e-32 | 34.43% (273) | acyl-CoA thioesterase II |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1644 | tesB1 | 2e-30 | 32.25% (276) | acyl-CoA thioesterase II TesB1 |
| M. gilvum PYR-GCK | Mflv_4143 | - | 1e-100 | 66.04% (265) | acyl-CoA thioesterase |
| M. tuberculosis H37Rv | Rv1618 | tesB1 | 1e-30 | 32.25% (276) | acyl-CoA thioesterase II TesB1 |
| M. leprae Br4923 | MLBr_01278 | tesB | 3e-31 | 32.25% (276) | acyl CoA thioesterase II |
| M. abscessus ATCC 19977 | MAB_2891c | - | 2e-32 | 33.70% (270) | acyl-CoA thioesterase II TesB2 |
| M. marinum M | MMAR_2421 | tesB1 | 6e-33 | 33.33% (276) | acyl-CoA thioesterase II TesB1 |
| M. avium 104 | MAV_3169 | - | 8e-32 | 32.97% (276) | Acyl-CoA thioesterase |
| M. thermoresistible (build 8) | TH_3637 | - | 1e-104 | 69.17% (253) | PUTATIVE acyl-CoA thioesterase |
| M. ulcerans Agy99 | MUL_1599 | tesB1 | 8e-33 | 33.33% (276) | acyl-CoA thioesterase II TesB1 |
| M. vanbaalenii PYR-1 | Mvan_2198 | - | 1e-100 | 66.17% (266) | acyl-CoA thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2421|M.marinum_M MPAGDEPNVRDEAKSDFEELLAVLDLKRVA-DDRFIGAHPSKNPMRTFGG
MUL_1599|M.ulcerans_Agy99 --------MRDEAKSDFEELLAVLDLKRVA-DDRFIGAHPSKNPMRTFGG
MAV_3169|M.avium_104 MPAGAE-SQEPNTTADFEELLATLDLRRVA-DDLFVGSHPSKNPMRTFGG
Mb1644|M.bovis_AF2122/97 -------MPDGKPMSDFDELLAVLDLNAVA-SDLFTGSHPSKNPLRTFGG
Rv1618|M.tuberculosis_H37Rv -------MPDGKPMSDFDELLAVLDLNAVA-SDLFTGSHPSKNPLRTFGG
MLBr_01278|M.leprae_Br4923 ----MKRLWEKKTMSDFEELLAVLDLNRVA-DDLFIGSHPSKNPLRTFGG
MAB_2891c|M.abscessus_ATCC_199 ----------------MADIEEILTLEQLE-KDIFRGNVTPSNLRRTFGG
Mflv_4143|M.gilvum_PYR-GCK ----------------MSRLLELLEVTQAQ-PPTWRGPASGPQGKRAYGG
Mvan_2198|M.vanbaalenii_PYR-1 ----------------MSTLLGLLDVTGAG-PQSWRGRAGGPAGKRAYGG
TH_3637|M.thermoresistible__bu ------------------------VAAGDG-ADQWIGAASGPAGKRAYGG
MSMEG_2470|M.smegmatis_MC2_155 ----------------MSELPRLLDLDEHDDEDTWTGPASGPDGKRAFGG
: * *::**
MMAR_2421|M.marinum_M LLMAQSFVASSRTLLRDDLPPSALSVHFINGGDTTKDIEFQVVRLRDERR
MUL_1599|M.ulcerans_Agy99 LLMAQSFVANSRTLLRDDLPPSALSVHFINGGDTTKDIEFQVVRLRDERR
MAV_3169|M.avium_104 QLMSQSFVASSRSLIRDDLPPSALSVHFINGGDTGKDIEYRVTRLRDERR
Mb1644|M.bovis_AF2122/97 QLMAQSFVASSRTLTRHHLPPSAFSVHFINGGDTAKDIEFQVIRLRDERR
Rv1618|M.tuberculosis_H37Rv QLMAQSFVASSRTLTRHHLPPSAFSVHFINGGDTAKDIEFQVIRLRDERR
MLBr_01278|M.leprae_Br4923 QLVAQSFVASSRTLIRDDLPPSAFSVHFINGGDTAKEIEFHVVRLRDERR
MAB_2891c|M.abscessus_ATCC_199 QVAGQSLVSAVRTVEPEYLVHS-LHGYFLRPGNPNEPTVFLVDRVRDGRS
Mflv_4143|M.gilvum_PYR-GCK QLAAQSLAAAARTVD-RSKAPTAMHLQFLRGGVAGDPTDYAVVNVHDGRT
Mvan_2198|M.vanbaalenii_PYR-1 QLAAQSLAAAARTVD-PAKAPTAMHLQFLRGGEAGDPVDYRVEQIYDGRT
TH_3637|M.thermoresistible__bu QLVAQSLAAAARTVP-AERPPTSLHLQFLRGGDAGAPVEYTVTGLLDGRT
MSMEG_2470|M.smegmatis_MC2_155 LRAAQSLAAAARTVG-DDRAPTNMHMQFLRGGDAGEPARYRVHRVYDGRT
.**:.: *:: : : *:. * . : * : * *
MMAR_2421|M.marinum_M FANRRIDAVQNGTLLSSAMISYMSGGRGLEHGVEPPPVADPETRPPIGEL
MUL_1599|M.ulcerans_Agy99 FANRRIDAVQNGTLLSSAMISYMSGGRGLEHGVEPPPVADPETRPPIGEL
MAV_3169|M.avium_104 FANRRVDAVQDGTLLCSALISYMAGGRGLEHGVDPPRVADPETQPTIVEL
Mb1644|M.bovis_AF2122/97 FANRRVDAVQDGTLLSSAMVSYMAGGRGLEHALDPPQVAEPHTRPPIGEL
Rv1618|M.tuberculosis_H37Rv FANRRVDAVQDGTLLSSAMVSYMAGGRGHEHALDPPQVAEPHTRPPIGEL
MLBr_01278|M.leprae_Br4923 FANRRVDAIQDGMLLSSAMASYMSGGCGLEHAVEPPEAAEPHTRPPIGEL
MAB_2891c|M.abscessus_ATCC_199 FVTRRVTAIQDGQAIFSMSASFQTLDTGIEHQDLMPPVPDPEDLPDAQEQ
Mflv_4143|M.gilvum_PYR-GCK AASRRVDATQGERLLTTSTVSFAVALPGPEHGRRELPAEDPESLPQTGPP
Mvan_2198|M.vanbaalenii_PYR-1 AASRRVDSTQNGRLLTTATVSFAAALPGPEHGQRDLGGADPESLPRTGPA
TH_3637|M.thermoresistible__bu TAARRVDARQDGRLLTTATVSFAVPLSGPRHGWRTELPGDPEQLPRTGPA
MSMEG_2470|M.smegmatis_MC2_155 ASARRVDAHEHGRLLTTATVSFATPLPGPEHGRRTSVPHDPEALPRTGPP
**: : : : : *: * .* :*. *
MMAR_2421|M.marinum_M LRGYEETVPHFVNALQPIEWRYTNDPSWVMRDKGERLHYNRVWVKALGKL
MUL_1599|M.ulcerans_Agy99 LRGYEETVPHFVNALQPIEWRYTNDPSWVMRDKGERLHYNRVWVKALGKL
MAV_3169|M.avium_104 LRGYEETVPHFVNALQPIEWRYTNDPAWVMRTKGERLPHNRVWVKALGKL
Mb1644|M.bovis_AF2122/97 LRGYEETVPHFVNALQPIEWRYANDPAWIMRDKGDRLAYNRVWVKALGEM
Rv1618|M.tuberculosis_H37Rv LRGYEETVPHFVNALQPIEWRYANDPAWIMRDKGDRLAYNRVWVKALGEM
MLBr_01278|M.leprae_Br4923 LRGYEQIVQHFVNALQPVEWRYVNDPSWVMRNKGQRLAYNRVWVKALGAL
MAB_2891c|M.abscessus_ATCC_199 DSFNRDLFRQFA------EWDIRIVPDELMDRNPRLAAQQRVWFRCRKHL
Mflv_4143|M.gilvum_PYR-GCK GP--------------APSLPLDELDLRYVDDGSGEGFVRRLWWRTVVDL
Mvan_2198|M.vanbaalenii_PYR-1 GP--------------APSMPLHELDLRLVDDGHGEEFVRRLWWRATVDL
TH_3637|M.thermoresistible__bu GP--------------APSMPLDELDIRIADEGGGAGFVRRFWWRATVAL
MSMEG_2470|M.smegmatis_MC2_155 GP--------------APSLPLDEFDIRIADDTAGGGFTRRFWWRVTTAL
. .*.* : :
MMAR_2421|M.marinum_M PDDPILHTATMLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
MUL_1599|M.ulcerans_Agy99 PDDPILHTATMLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
MAV_3169|M.avium_104 PDDPVLHTAAMVYSSDTTVLDSVITTHGLSWGFDRIFAASANHSIWFHRQ
Mb1644|M.bovis_AF2122/97 PDDPVLHTATLLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
Rv1618|M.tuberculosis_H37Rv PDDPVLHTATLLYSSDTTVLDSVITTHGLSWGFDRIFAASANHSVWFHRQ
MLBr_01278|M.leprae_Br4923 PNDPTLHTAAMLYSTDTTVLDSVITTHGLSWGFDRIFAVSANHSVWFHRQ
MAB_2891c|M.abscessus_ATCC_199 PDDPVLHICALAYMSDLTLLSSSKVPH----RDTVLQTASLDHALWFLRP
Mflv_4143|M.gilvum_PYR-GCK PEDPLLHTLIAVYVTDVYLIDPALQVHGHSMRARTHRSGTTDSSIWFHHE
Mvan_2198|M.vanbaalenii_PYR-1 PDDPLLHTLIAVYVTDVYLIDPALQVHGHSMRSRTHRSGTTDSSVWFHRE
TH_3637|M.thermoresistible__bu PDDPLVHTLVAAYVTDVYLIDPALQVHGFSMRARTHRSGTTDSSLWFHRR
MSMEG_2470|M.smegmatis_MC2_155 PDDALLHTMVALYITDLYGIDPALGVHGLTMRSRSHRSGTTDSSMWFHRR
*:*. :* * :* :.. * : : : ::** :
MMAR_2421|M.marinum_M VDFNDWVLYSTSSPVAADSRGLGTGHFFNRTGQPVATVVQEGVLKYFPAA
MUL_1599|M.ulcerans_Agy99 VDFNDWVLYSTSSPVAADSRGLGTGHFFNRTGQPVATVVQEGVLKYFPAA
MAV_3169|M.avium_104 VDFNDWVLYSTSSPVAADSRGLGTGHFFDRSGQPLATVMQEGVLKYFPSA
Mb1644|M.bovis_AF2122/97 VNFDDWVLYSTSSPVAADSRGLGSGHFFDRSGKLIATVVQEGVLKYFPAT
Rv1618|M.tuberculosis_H37Rv VNFDDWVLYSTSSPVAADSRGLGSGHFFDRSGKLIATVVQEGVLKYFPAT
MLBr_01278|M.leprae_Br4923 VNFDDWVLYSTSSPVAADSRGLGTGHLFDRSGQLIATVVQEGVLKYFPAS
MAB_2891c|M.abscessus_ATCC_199 FRADEWMLYDETSPSAGFGRALTQGRIFNRDGTMVAAVVQEGLTRIERNP
Mflv_4143|M.gilvum_PYR-GCK VRAGEWNLLECRSPAAARGRGVVTANLIRRDGVLAATLVQEGLIADREPA
Mvan_2198|M.vanbaalenii_PYR-1 VRADQWNLLECRSPAAARGRGVVTACLIRSDGVLAATLVQEGLVAEREPA
TH_3637|M.thermoresistible__bu IRADEWNLLECTSPAAGRGRAVVNASLIRADGVIAATLAQEGLIADRGQP
MSMEG_2470|M.smegmatis_MC2_155 VRADEWNLLEQTSPAAARGRGIITSSLVQLDGSVVATLVQEGLMAERTTD
. .:* * . ** *. .*.: . :. * *:: ***:
MMAR_2421|M.marinum_M RR---------
MUL_1599|M.ulcerans_Agy99 RR---------
MAV_3169|M.avium_104 RR---------
Mb1644|M.bovis_AF2122/97 PDSAAGRS---
Rv1618|M.tuberculosis_H37Rv PDSAAGRS---
MLBr_01278|M.leprae_Br4923 HR---------
MAB_2891c|M.abscessus_ATCC_199 EQASVARGNMA
Mflv_4143|M.gilvum_PYR-GCK P-PA-------
Mvan_2198|M.vanbaalenii_PYR-1 THPAG------
TH_3637|M.thermoresistible__bu PR---------
MSMEG_2470|M.smegmatis_MC2_155 -----------