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SAHYVAMHMSDGIINAPISMLFVAIAVAALGICAWRAREELDERTVPLAGLVAAFVFAVQMVNFPILPGV SGHLLGGALAAILVGPYTGALCVSIVLIVQALLFADGGVTALGTNITNMSVIGVAAGYGTAVLLYRVLRR RRADLAVPVVGVIAFVSAVVGTVCAAMGFVAQYALGGAATTSLGTVAAYMFGTHVLIGIGEGVITALTVM AVVRARPDLVYLLRSHPARQAVPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4058 | - | - | 100% (235) | cobalamin (vitamin B12) biosynthesis CbiM protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0665 | - | 9e-05 | 27.52% (149) | ethanolamine transporter |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2607 | cbiM | 4e-93 | 77.73% (220) | cobalamin biosynthesis protein CbiM |
| M. thermoresistible (build 8) | TH_3322 | - | 8e-18 | 32.17% (230) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2291 | - | 1e-108 | 83.76% (234) | cobalamin (vitamin B12) biosynthesis CbiM protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4058|M.gilvum_PYR-GCK MSAHYVAMHMSDGIIN----------------------------------
Mvan_2291|M.vanbaalenii_PYR-1 MTVDHVAMHMSDGIVN----------------------------------
MSMEG_2607|M.smegmatis_MC2_155 -------MHMSDGIVN----------------------------------
TH_3322|M.thermoresistible__bu -------MHIAEGFLP----------------------------------
MMAR_0665|M.marinum_M MAGDHEVAHLAGGHLAGTDSHLESPTYLQKRQLRTGSAGWLLLAGLGVSY
*:: * :
Mflv_4058|M.gilvum_PYR-GCK -----------APISMLFVAIAVAALGICAWRAREELDER--TVPLAGLV
Mvan_2291|M.vanbaalenii_PYR-1 -----------APISVLFGIIAVVALGICAWRAREELDER--TVPLAGLV
MSMEG_2607|M.smegmatis_MC2_155 -----------VQTSLVFGALAVAALGVCALRARDELDER--TVPLAGLV
TH_3322|M.thermoresistible__bu -----------PVHAVAWTVAAAPFVIYGARQVVITVRRQPSSGPLLAAV
MMAR_0665|M.marinum_M VISGDYSGWNFGLARGGFGGLAIAAVVIAAMYLALVLSMAELSSALPAAG
: * : * : : .* .
Mflv_4058|M.gilvum_PYR-GCK AAFVFAVQMVN---------------------------------------
Mvan_2291|M.vanbaalenii_PYR-1 AAFIFAVQMVN---------------------------------------
MSMEG_2607|M.smegmatis_MC2_155 AAFIFAVQMVN---------------------------------------
TH_3322|M.thermoresistible__bu GAFSFVMSAIK---------------------------------------
MMAR_0665|M.marinum_M GGYTFARRALGPWGGFATGTAVLIEYSIAPAAIATFIGAYVQSLGLFGIR
..: *. :
Mflv_4058|M.gilvum_PYR-GCK ---------FPILPGVSGHLLGGALAAILVGP------------------
Mvan_2291|M.vanbaalenii_PYR-1 ---------FPILPGVSGHLLGGALAAILVGP------------------
MSMEG_2607|M.smegmatis_MC2_155 ---------FPILPGVSGHLLGGALAAILVGP------------------
TH_3322|M.thermoresistible__bu ---------LPSVTGSSSHPTGTGLGTAIFRP------------------
MMAR_0665|M.marinum_M NGWWVYLTIYALFIGIHLSGVGEALKVMFIITGVALVGLVVFAIAAVGHF
. . * * .* . :. .
Mflv_4058|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2291|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2607|M.smegmatis_MC2_155 --------------------------------------------------
TH_3322|M.thermoresistible__bu --------------------------------------------------
MMAR_0665|M.marinum_M RLANLVDITPSDAVGASAFLPHGYLGVWSALPFAIWFFLAVEGVPLAAEE
Mflv_4058|M.gilvum_PYR-GCK -----------YTGALCVSIVLIVQALLFADGG-------------VTAL
Mvan_2291|M.vanbaalenii_PYR-1 -----------FTGALCVAIVLIVQAFLFADGG-------------VTAL
MSMEG_2607|M.smegmatis_MC2_155 -----------YTGALCIAIVLVVQSLLFADGG-------------VSAL
TH_3322|M.thermoresistible__bu -----------PVMAFLGSIVLLFQALLLAHGG-------------ITTL
MMAR_0665|M.marinum_M TADPARNVPRGITAAFSVLVLTCAAVLLLATGAGGAAAMSSSGNPLVAAL
. *: :: :*:* *. :::*
Mflv_4058|M.gilvum_PYR-GCK GTNITN-----MSVIGVAAGYGTAVLLYR----------------VLRRR
Mvan_2291|M.vanbaalenii_PYR-1 GANITN-----MSVFGVAAGYASALLLYR----------------LARRG
MSMEG_2607|M.smegmatis_MC2_155 GTNITN-----MALIGVAAGYATAVVLST----------------VLRGR
TH_3322|M.thermoresistible__bu GANAFS-----MAIAGPWAGFAVYVALRR----------------AGVG-
MMAR_0665|M.marinum_M GPTVAATVVNYIGLAGLVASFFSIIYAYSRQLFALSRAGYLPTALSITNS
*.. :.: * *.: :
Mflv_4058|M.gilvum_PYR-GCK RADLAVP--VVGVIAFVSAVVG---------TVCAAMGFVAQY-------
Mvan_2291|M.vanbaalenii_PYR-1 RDDVAVP--VVGGIAFVSAVIG---------TVCAAMGFVLEY-------
MSMEG_2607|M.smegmatis_MC2_155 GAAGSPPDRHIGVVAFVAALVG---------TVCAAMGFVVEY-------
TH_3322|M.thermoresistible__bu ----VLP--AVFALAFVADLVT---------YIVTSIQLALAFP------
MMAR_0665|M.marinum_M RKAPTLALIVPGVIGFALSVTGEGDLLLNMAVFGATLSYVLMMISHIVLR
. :.*. : . ::: .
Mflv_4058|M.gilvum_PYR-GCK -----ALGGAATTSLGTVAAYMFGTHVLIGIGEGVITALTVMAVVRARPD
Mvan_2291|M.vanbaalenii_PYR-1 -----SLGGAATTSLGAVAGYMFGTHVLIGVGEGIITALTVMAVVRARPD
MSMEG_2607|M.smegmatis_MC2_155 -----VIGGVATTSIQAVAGYMFGTHVLIGIGEGIITALTVTAVARVRPD
TH_3322|M.thermoresistible__bu -----AAEGGFTESLVEFLGVFALTQVPLAVVEGLITVVLVRILMHVASS
MMAR_0665|M.marinum_M RRAADMARPYRTPGGIATSGFALLVAATALIATFLVDTVAALCCLGVFCA
* . . . . : :: .: . .
Mflv_4058|M.gilvum_PYR-GCK LVYLLRSHPARQAVPV-----------------
Mvan_2291|M.vanbaalenii_PYR-1 LVYLLRTNRVRTAVPA-----------------
MSMEG_2607|M.smegmatis_MC2_155 LVYLLRRQ--RQEVAA-----------------
TH_3322|M.thermoresistible__bu ELLRLRFLKSHEVPAGADVEPGSEREEVQR---
MMAR_0665|M.marinum_M FILYFALYSRHQLVANSPDEELAGSQDFESELQ
: : : .