For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. vanbaalenii PYR-1 Mvan_2291 (-)

annotation: cobalamin (vitamin B12) biosynthesis CbiM protein
coordinates: 2446702 - 2447409
length: 235

MTVDHVAMHMSDGIVNAPISVLFGIIAVVALGICAWRAREELDERTVPLAGLVAAFIFAVQMVNFPILPG
VSGHLLGGALAAILVGPFTGALCVAIVLIVQAFLFADGGVTALGANITNMSVFGVAAGYASALLLYRLAR
RGRDDVAVPVVGGIAFVSAVIGTVCAAMGFVLEYSLGGAATTSLGAVAGYMFGTHVLIGVGEGIITALTV
MAVVRARPDLVYLLRTNRVRTAVPA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2291--100% (235)cobalamin (vitamin B12) biosynthesis CbiM protein
M. vanbaalenii PYR-1Mvan_3228-4e-0530.11% (186) BioY protein
M. vanbaalenii PYR-1Mvan_1872-5e-0524.58% (240) NADH dehydrogenase subunit N

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4058-1e-10883.76% (234) cobalamin (vitamin B12) biosynthesis CbiM protein
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_2607cbiM5e-9174.12% (228) cobalamin biosynthesis protein CbiM
M. thermoresistible (build 8)TH_3322-2e-1632.40% (179) PUTATIVE -
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_2291|M.vanbaalenii_PYR-1       MTVDHVAMHMSDGIVNAPISVLFGIIAVVALGICAWRAREELDER--TVP
Mflv_4058|M.gilvum_PYR-GCK          MSAHYVAMHMSDGIINAPISMLFVAIAVAALGICAWRAREELDER--TVP
MSMEG_2607|M.smegmatis_MC2_155      -------MHMSDGIVNVQTSLVFGALAVAALGVCALRARDELDER--TVP
TH_3322|M.thermoresistible__bu      -------MHIAEGFLPPVHAVAWTVAAAPFVIYGARQVVITVRRQPSSGP
                                           **:::*::    :: :   *.  :   * :.   : .:  : *

Mvan_2291|M.vanbaalenii_PYR-1       LAGLVAAFIFAVQMVNFPILPGVSGHLLGGALAAILVGPFTGALCVAIVL
Mflv_4058|M.gilvum_PYR-GCK          LAGLVAAFVFAVQMVNFPILPGVSGHLLGGALAAILVGPYTGALCVSIVL
MSMEG_2607|M.smegmatis_MC2_155      LAGLVAAFIFAVQMVNFPILPGVSGHLLGGALAAILVGPYTGALCIAIVL
TH_3322|M.thermoresistible__bu      LLAAVGAFSFVMSAIKLPSVTGSSSHPTGTGLGTAIFRPPVMAFLGSIVL
                                    * . *.** *.:. :::* :.* *.*  * .*.: :. * . *:  :***

Mvan_2291|M.vanbaalenii_PYR-1       IVQAFLFADGGVTALGANITNMSVFGVAAGYASALLLYRLARRGRDDVAV
Mflv_4058|M.gilvum_PYR-GCK          IVQALLFADGGVTALGTNITNMSVIGVAAGYGTAVLLYRVLRRRRADLAV
MSMEG_2607|M.smegmatis_MC2_155      VVQSLLFADGGVSALGTNITNMALIGVAAGYATAVVLSTVLRGRGAAGSP
TH_3322|M.thermoresistible__bu      LFQALLLAHGGITTLGANAFSMAIAGPWAGFAVYVALRRAGVG-----VL
                                    :.*::*:*.**:::**:*  .*:: *  **:.  : *             

Mvan_2291|M.vanbaalenii_PYR-1       P--VVGGIAFVSAVIGTVCAAMGFVLEY-SLGGAATTSLGAVAGYMFGTH
Mflv_4058|M.gilvum_PYR-GCK          P--VVGVIAFVSAVVGTVCAAMGFVAQY-ALGGAATTSLGTVAAYMFGTH
MSMEG_2607|M.smegmatis_MC2_155      PDRHIGVVAFVAALVGTVCAAMGFVVEY-VIGGVATTSIQAVAGYMFGTH
TH_3322|M.thermoresistible__bu      P--AVFALAFVADLVTYIVTSIQLALAFPAAEGGFTESLVEFLGVFALTQ
                                    *   :  :***: ::  : ::: :.  :    *  * *:  . . :  *:

Mvan_2291|M.vanbaalenii_PYR-1       VLIGVGEGIITALTVMAVVRARPDLVYLLRTNRVRTAVPA----------
Mflv_4058|M.gilvum_PYR-GCK          VLIGIGEGVITALTVMAVVRARPDLVYLLRSHPARQAVPV----------
MSMEG_2607|M.smegmatis_MC2_155      VLIGIGEGIITALTVTAVARVRPDLVYLLRRQ--RQEVAA----------
TH_3322|M.thermoresistible__bu      VPLAVVEGLITVVLVRILMHVASSELLRLRFLKSHEVPAGADVEPGSERE
                                    * :.: **:**.: *  : :. .. :  **    :   .           

Mvan_2291|M.vanbaalenii_PYR-1       ----
Mflv_4058|M.gilvum_PYR-GCK          ----
MSMEG_2607|M.smegmatis_MC2_155      ----
TH_3322|M.thermoresistible__bu      EVQR