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MDTTIGASAGGRYGERVSTSTDVLLVDTRDRIQTLTLNRPGSRNALSAALRSRLFEALRQAQADDEVDVV ILTGADPVFCAGLDLKELGDTTELPDISPKWPPMTKPVIGAINGAAVTGGLEIALYCDILIASDQARFAD THARVGLLPTWGLSVRLPQKVGVGMARRMSMTGDYLSADEALRCGLVTQVVPHAELQDTARQVATSIVGN NQKAVRALLASYHDIDDAQNGAALWQEAAAAREWMKSTSGDDIAESRSNVIERGRTQVRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4034 | - | - | 100% (270) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4495 | - | 4e-46 | 44.36% (257) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4596 | - | 2e-33 | 36.64% (232) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2855 | echA16 | 1e-104 | 75.40% (248) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv2831 | echA16 | 1e-104 | 75.40% (248) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 6e-31 | 36.14% (202) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3124 | - | 8e-77 | 58.94% (246) | enoyl-CoA hydratase |
| M. marinum M | MMAR_1903 | echA16_2 | 1e-103 | 74.40% (250) | enoyl-CoA hydratase, EchA16_2 |
| M. avium 104 | MAV_3689 | - | 1e-103 | 75.00% (248) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2641 | - | 1e-111 | 80.97% (247) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3798 | - | 1e-114 | 80.31% (254) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 7e-30 | 35.29% (204) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_2320 | - | 1e-139 | 91.08% (269) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4034|M.gilvum_PYR-GCK MDTTIGASAGGRYGERVSTSTDVLLVDTRDRIQTLTLNRPGSRNALSAAL
Mvan_2320|M.vanbaalenii_PYR-1 MDTTIGAQQGCGYGERMSTATDVLLIDTTDRIRTLTLNRPGSRNALSAAL
MSMEG_2641|M.smegmatis_MC2_155 -----------------MADSPVLLVDTTDRVRTLTLNRPQSRNALSAEL
TH_3798|M.thermoresistible__bu -------------VIVMTSTDDVLLIDTSDRIRTLTLNRPRARNALSAEL
Mb2855|M.bovis_AF2122/97 ------------------MTDDILLIDTDERVRTLTLNRPQSRNALSAAL
Rv2831|M.tuberculosis_H37Rv ------------------MTDDILLIDTDERVRTLTLNRPQSRNALSAAL
MMAR_1903|M.marinum_M ------------------MTNEILLIDTAERVLTLTLNRPQSRNALSAAL
MAV_3689|M.avium_104 ------------------MTDEILLSNTEERVRTLTLNRPQARNALSAAL
MAB_3124|M.abscessus_ATCC_1997 ------------------MTEPILLTHTEDRICTITLNRPQARNALSTAL
MLBr_02402|M.leprae_Br4923 ------------------MKYDTILVDGYQRVGIITLNRPQALNALNSQM
MUL_0210|M.ulcerans_Agy99 ------------------MSYETILVERDQRVGIITLNRPQALNALNSQV
:* . :*: :***** : ***.: :
Mflv_4034|M.gilvum_PYR-GCK RSRLFEALRQAQADDEVDVVILTGADPVFCAGLDLKELGDTTELPDISP-
Mvan_2320|M.vanbaalenii_PYR-1 RGRLFEALREAQADDDVDVVILTGADPVFCAGLDLKELGDTTELPDISP-
MSMEG_2641|M.smegmatis_MC2_155 RSTFFRALSDAQNDDDVDVVIVTGADPVFCAGLDLKELGDTTELPDISP-
TH_3798|M.thermoresistible__bu RQRFFGALADADADDAVDVVIVTGADPVFCAGLDLKELGDTTELPDISP-
Mb2855|M.bovis_AF2122/97 RDRFFAALADAEADDDIDVVILTGADPVFCAGLDLKELAGQTALPDISP-
Rv2831|M.tuberculosis_H37Rv RDRFFAALADAEADDDIDVVILTGADPVFCAGLDLKELAGQTALPDISP-
MMAR_1903|M.marinum_M RDQFFAALAAAETDDDVDVIILTGADPVFCAGLDLKELGGQSALPDISP-
MAV_3689|M.avium_104 RDRFFGALADAETDDDVDVVIITGADPVFCAGLDLKELGGSSALPDISP-
MAB_3124|M.abscessus_ATCC_1997 GEEIVKAVTAADADENVDVMILTAADPVFCAGVDLKELGSGDRAESLDP-
MLBr_02402|M.leprae_Br4923 MNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDAD
MUL_0210|M.ulcerans_Agy99 MNEVTSAAAELDNDPGIGAIIITGSAKAFAAGADIKEMADLTFSEAFDAD
. * : * :..:::*.: .*.** *:**:.. :..
Mflv_4034|M.gilvum_PYR-GCK ------KWPPMTKPVIGAINGAAVTGGLEIALYCDILIASDQARFADTHA
Mvan_2320|M.vanbaalenii_PYR-1 ------KWPPMDKPVIGAINGAAVTGGLEIALYCDILIASEQARFADTHA
MSMEG_2641|M.smegmatis_MC2_155 ------KWPDMTKPVIGAINGAAVTGGLELALYCDILIASENAKFADTHA
TH_3798|M.thermoresistible__bu ------KWPPMTKPVIGAINGAAVTGGLELALYCDILIASENARFADTHA
Mb2855|M.bovis_AF2122/97 ------RWPAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHA
Rv2831|M.tuberculosis_H37Rv ------RWPAMTKPVIGAINGAAVTGGLELALYCDILIASEHARFADTHA
MMAR_1903|M.marinum_M ------RWPALTKPVIGAINGAAVTGGLELALYCDILIASEQARFADTHA
MAV_3689|M.avium_104 ------RWPALTKPVIGAINGAAVTGGLELALYCDILIASENARFADTHA
MAB_3124|M.abscessus_ATCC_1997 ------WWPELSKPVIGAINGAAVTGGLELALACDILIASEKARFADTHA
MLBr_02402|M.leprae_Br4923 FFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEI
MUL_0210|M.ulcerans_Agy99 FFAAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEI
. : .* *.*: * *: ** *:*: **::**:: *:*.:..
Mflv_4034|M.gilvum_PYR-GCK RVGLLPTWGLSVRLPQKVGVGMARRMSMTGDYLSADEALRCGLVTQVVPH
Mvan_2320|M.vanbaalenii_PYR-1 RVGLMPTWGLSVRLPQKVGVGMARRMSMTGDYLSADEALRCGLVTQVVPH
MSMEG_2641|M.smegmatis_MC2_155 RVGLMPTWGLSVRLPQKVGVGLARRMSLTGDYLSAQDALRAGLVTEVVAH
TH_3798|M.thermoresistible__bu RVGLMPTWGMSVRLPQKVGVGLARRMSLTGDYLSADDALRAGLVTEVVPH
Mb2855|M.bovis_AF2122/97 RVGLLPTWGLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAH
Rv2831|M.tuberculosis_H37Rv RVGLLPTWGLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAH
MMAR_1903|M.marinum_M RVGLLPTWGLSVRLPQKVGVGLARRMSLTGDYLSATDALRAGLVTEVVEH
MAV_3689|M.avium_104 RVGLLPTWGLSVRLPQKVGIGLARRMSLTGDYLSAADALRAGLVTEVVPH
MAB_3124|M.abscessus_ATCC_1997 RVGILPTWGLTTLLPLSVGRGLARRMSLTGDYLSAEDALRAGLVTEVVAH
MLBr_02402|M.leprae_Br4923 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLA
MUL_0210|M.ulcerans_Agy99 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPA
::*::* * : *. :* . * : :** :.* :* *.***:.**
Mflv_4034|M.gilvum_PYR-GCK AELQDTARQVATSIVGNNQKAVRALLASYHDIDDAQNGAALWQEAAAARE
Mvan_2320|M.vanbaalenii_PYR-1 AELLDTARQIATSIVGNNQNAVRALLASYHGIDDAQNGAALWQEAAAARE
MSMEG_2641|M.smegmatis_MC2_155 DDLLTAARRVAASIVGNNQKAVRALLDSYHRIDALQTGGALWAEAEAARQ
TH_3798|M.thermoresistible__bu DRLMEAARRVAASIVGNNQRAVRALLASYHRIDESQTNGQLWMEAEAARR
Mb2855|M.bovis_AF2122/97 DQLLPTARRVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQ
Rv2831|M.tuberculosis_H37Rv DQLLPTARRVAASIVGNNQNAVRALLASYHRIDESQTAAGLWLEACAAKQ
MMAR_1903|M.marinum_M QQLLPAARQVAASIVGNNQNAVRALLASYHRIDESSTAQGLWLEATAARE
MAV_3689|M.avium_104 DQLLGAARAVAASIVGNNQNAVRALLTSYHRIDDAQTSAGLWQEAMAARQ
MAB_3124|M.abscessus_ATCC_1997 NELLPAAKRLAATIAGNNQPAVRELLASYRRIESELVGNGLQVALDDAHR
MLBr_02402|M.leprae_Br4923 DDLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHS
MUL_0210|M.ulcerans_Agy99 DDLLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHS
* *: :*::* .: *.* : . * :
Mflv_4034|M.gilvum_PYR-GCK WMK-STSGDDIAESRSNVIERGRTQVRP
Mvan_2320|M.vanbaalenii_PYR-1 WMK-SASGDDIAASRSSVMDRGRTQVRQ
MSMEG_2641|M.smegmatis_MC2_155 WMR-STSGDDIAASRASVIERGRSQVR-
TH_3798|M.thermoresistible__bu WMA-STTGDDIAASRASVIERGRAQVR-
Mb2855|M.bovis_AF2122/97 FC---TSGDTIAANREAVLQRGRAQVR-
Rv2831|M.tuberculosis_H37Rv FR---TSGDTIAANREAVLQRGRAQVR-
MMAR_1903|M.marinum_M FR---TSGDDIAANREAVLNRGRSQVR-
MAV_3689|M.avium_104 FR---TSGDDIAANREAVLARGRSQVR-
MAB_3124|M.abscessus_ATCC_1997 WIDQNSIAEGVEARRTAIMERGRSQNA-
MLBr_02402|M.leprae_Br4923 TFVTDDQSEGMAAFIEKRAPQFTHR---
MUL_0210|M.ulcerans_Agy99 AFATADQSEGMAAFIEKRPPNFTHR---
.: : . :