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VPVLSALAIVPSAPVMVPELASGAAAETADLRAAALEAVRGLPARWIAIGVAEQDGVYGPDRAGTFGGYG VDIRVALSPEATTSAPTALPLCALICGWLRGQARPDARVEARAYRAEHAGPVALGFGARLREQIDADAAD IGVVIVADGANTLTPAAPGGYDEDSPTVQSALDDALAAGDCAALTRLPSGVLGRVAYQVLAGLAGTGPRT AAELYRGAPYGVGYFAGVWTP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3963 | - | - | 100% (232) | hypothetical protein Mflv_3963 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2747c | - | 9e-75 | 59.31% (231) | hypothetical protein Mb2747c |
| M. tuberculosis H37Rv | Rv2728c | - | 9e-75 | 59.31% (231) | hypothetical protein Rv2728c |
| M. leprae Br4923 | MLBr_00994 | - | 1e-66 | 55.17% (232) | hypothetical protein MLBr_00994 |
| M. abscessus ATCC 19977 | MAB_3045c | - | 3e-56 | 53.10% (226) | hypothetical protein MAB_3045c |
| M. marinum M | MMAR_1985 | - | 4e-70 | 57.14% (231) | hypothetical protein MMAR_1985 |
| M. avium 104 | MAV_3621 | - | 1e-70 | 58.70% (230) | hypothetical protein MAV_3621 |
| M. smegmatis MC2 155 | MSMEG_2733 | - | 6e-71 | 57.64% (229) | hypothetical protein MSMEG_2733 |
| M. thermoresistible (build 8) | TH_2716 | - | 3e-05 | 29.71% (239) | PUTATIVE putative acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_3371 | - | 4e-70 | 57.14% (231) | hypothetical protein MUL_3371 |
| M. vanbaalenii PYR-1 | Mvan_2433 | - | 2e-84 | 69.00% (229) | hypothetical protein Mvan_2433 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3963|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2433|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2747c|M.bovis_AF2122/97 --------------------------------------------------
Rv2728c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00994|M.leprae_Br4923 --------------------------------------------------
MMAR_1985|M.marinum_M --------------------------------------------------
MUL_3371|M.ulcerans_Agy99 --------------------------------------------------
MAV_3621|M.avium_104 --------------------------------------------------
MSMEG_2733|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3045c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2716|M.thermoresistible__bu VTTDTTVSLAEIADTAAELAELRQSALEIVRRAWSVERSRGLLDGPSPAF
Mflv_3963|M.gilvum_PYR-GCK MVPVLSALAIVPSAPVMVPELASGAAAETADLR---------AAALEAVR
Mvan_2433|M.vanbaalenii_PYR-1 MELMLSAIVIVPSAPVMVPVLASSAAAETEDLR---------AAAVSAAA
Mb2747c|M.bovis_AF2122/97 ---MLSAIGIVPSAPVLVPELAGAAAAELADLG---------AAVIAAAS
Rv2728c|M.tuberculosis_H37Rv ---MLSAIGIVPSAPVLVPELAGAAAAELADLG---------AAVIAAAS
MLBr_00994|M.leprae_Br4923 ---MLSAIAIVPSAPVLVPELTGAAAAEVADLR---------SAVLAVAA
MMAR_1985|M.marinum_M ---MLSAIAIIPSAPVLVPELTGLAGAEVADLR---------SAVVAAAS
MUL_3371|M.ulcerans_Agy99 ---MLSAIAIIPSAPVLVPELTGLAGAEVADLR---------SAVVAAVS
MAV_3621|M.avium_104 ---MLSVIAIVPSAPVLVPELAGTAADELAELS---------AATLAAAA
MSMEG_2733|M.smegmatis_MC2_155 ---MLSAIAIVPAAPLLVPELMGAAAAEMAPLR---------DAALAAAA
MAB_3045c|M.abscessus_ATCC_199 ---MNLSIAICPSTPLLVPELGGEAAAETGELR---------AASVTVAR
TH_2716|M.thermoresistible__bu DDALWSTVRDLGWPDVLVPESAGGAGGTLRELAVLTEVTGSVVAPLPLAA
: : . ::** . *. * * : .
Mflv_3963|M.gilvum_PYR-GCK GLPARWIAIGVAEQDGVYGP---DRAGTFGG--YGVDIRVALSP---EAT
Mvan_2433|M.vanbaalenii_PYR-1 QLPRRWIAVGVAAADGVHGP---ESVGTFAG--YGVDVRVGLS----GPG
Mb2747c|M.bovis_AF2122/97 LLPKSWIAVGTGRADDVVRP---TDVGTFAG--FGADVRVGLAP-QDGDG
Rv2728c|M.tuberculosis_H37Rv LLPKSWIAVGTGRADDVVRP---TDVGTFAG--FGADVRVGLAP-QDGDG
MLBr_00994|M.leprae_Br4923 CLPPCWIVVGTGRADDVVGPG--GCLGTFAG--FGADVRVRLSP-QVGGE
MMAR_1985|M.marinum_M SLPNHWVGIGVGPEDQVAGP---DAVGTFAG--FGVDVQVRLAP-ALGEQ
MUL_3371|M.ulcerans_Agy99 SLPNHWVGIGVDPEDQVAGP---EAVGTFAG--FGVDVQVRLAP-ALGEQ
MAV_3621|M.avium_104 LLPDRWLIVGTGAADQELGD---DAVGTFAG--FGMDVPVRLSPPADGRA
MSMEG_2733|M.smegmatis_MC2_155 ELPARWVSVGTGAADATFGP---DQCGTFAG--YGAAVPVTLGP----VT
MAB_3045c|M.abscessus_ATCC_199 SLPAQWIAIGVG--DGQYHA---DMSGTFAG--YGADVRVSLSD-----R
TH_2716|M.thermoresistible__bu TAAAAWCEGRPADGIAIVAPEPATAAGQTATGTFSTVPYGAVATRLVVLA
. * * . :. :.
Mflv_3963|M.gilvum_PYR-GCK TSAPTALPLCALIC-GWLRGQARPDARVEARAYRAEHAGPVALGFG----
Mvan_2433|M.vanbaalenii_PYR-1 SGEPTALPLCALIT-AWLRGLARPQAVAEVWACRGDQEPGAAADLG----
Mb2747c|M.bovis_AF2122/97 VAVPVELPLCALLT-AWVRGQARPEARAQVHVYASDHGSDAAVARG----
Rv2728c|M.tuberculosis_H37Rv VAVPVELPLCALLT-AWVRGQARPEARAQVHVYASDHGSDAAVARG----
MLBr_00994|M.leprae_Br4923 AELLVDFPVCALIA-AWVRGQSQLDASAQVRVYCGDHDPDMALACG----
MMAR_1985|M.marinum_M PGPPSDLPLCALLA-GWVRGQVRPAATAKIQVYAHGRESEDALVQG----
MUL_3371|M.ulcerans_Agy99 PGPPSDLPLCALLA-GWVRGQVRPAATAKIQVYAHGRESEDALVQG----
MAV_3621|M.avium_104 ETAPAALPLCVLLG-GWLRGQVQPRAAARARIYRADYDADTAVRRG----
MSMEG_2733|M.smegmatis_MC2_155 NITPVELPLSALVA-GWLRGRVAPQAVVDARVYAAATPAGDAVEIG----
MAB_3045c|M.abscessus_ATCC_199 MGKPAQLPLPVLIA-GWLRSRAEAD-EAEVRLVG---PATDALAFG----
TH_2716|M.thermoresistible__bu EADTAVLGVVDLTGPGVERTPVTPLDHGPAAHISLDRAPLRQIARGDDAI
: : * . * *
Mflv_3963|M.gilvum_PYR-GCK -----ARLREQIDADAADIGVVIVADGANTLTPAAPGGYDEDSPTVQSAL
Mvan_2433|M.vanbaalenii_PYR-1 -----RRLRAQLDAAPEEVGVLVVADGANTLTPAAPGGHDPDSPRVQAAL
Mb2747c|M.bovis_AF2122/97 -----RQLRADIDREPDPIGVLVVADGLNTLTPRAPGGYDPDGAGMQRAL
Rv2728c|M.tuberculosis_H37Rv -----RQLRADIDREPDPIGVLVVADGLNTLTPRAPGGYDPDGAGMQRAL
MLBr_00994|M.leprae_Br4923 -----RQLRVEIEQAPDPIGVLVVADGATTLTSSSPGGYDPSAADAELVL
MMAR_1985|M.marinum_M -----KLLRAEIDRTADPVGVLVVADGVNTLTPSAPGGYDPTGAPAQLLL
MUL_3371|M.ulcerans_Agy99 -----KLLRAEIDRTADPVGVLVVADGVNTLTPSAPGGYDPTGAPAQLLL
MAV_3621|M.avium_104 -----RQLRAELDALPEPVGVLVVADGANTLTPAAPGGHHPGDAAAQQAL
MSMEG_2733|M.smegmatis_MC2_155 -----RGLRTEIDATAEPVGVLVVADGAHTLSPSAPGGYRPESVAAQHAL
MAB_3045c|M.abscessus_ATCC_199 -----RALRGEIERRPVPPGVLIVADGANTLTDKAPGGYRPDAEAAQRAV
TH_2716|M.thermoresistible__bu ARHRDAVLRMRVAQVAELVGVAAAANEAATEYAKVRVAFDRPIGSFQAIK
** : . ** .*: * .. :
Mflv_3963|M.gilvum_PYR-GCK D------DALAAGDCAALTRLPSGVLGRVAYQVLAGLAG--------TGP
Mvan_2433|M.vanbaalenii_PYR-1 D------DALATGDTAALMRLPSTVLGRVAYQVLAGLAE--------PGP
Mb2747c|M.bovis_AF2122/97 D------DALASGDLAVLTRLPAQVLGRVAFQVLAGLAE--------PGP
Rv2728c|M.tuberculosis_H37Rv D------DALASGDLAVLTRLPAQVLGRVAFQVLAGLAE--------PGP
MLBr_00994|M.leprae_Br4923 D------DALASGDVAALTRLSCQISGRVAFQVLAGLVE--------PGP
MMAR_1985|M.marinum_M D------DALAGGDVAALARLPERVLGRPAFQVLAGLCG--------AGP
MUL_3371|M.ulcerans_Agy99 D------DALAGGDVAALARLPERVLGRPAFQVLAGLCG--------AGP
MAV_3621|M.avium_104 D------DALAGGDIAALRRLPGQILGRVAFGVLAGLAE--------PGP
MSMEG_2733|M.smegmatis_MC2_155 D------EALASGDAAALASLPDVSVGRVAHEVLAGLAG--------AAP
MAB_3045c|M.abscessus_ATCC_199 V------DALTRGDAASLRHLPDAITGRPAYQVLAGLVD--------SDV
TH_2716|M.thermoresistible__bu HRLVDQRAAIEVGRALVNRAADACDHGQPDTEALVSLAVFWAVDSLRTVP
*: * *: .*..* .
Mflv_3963|M.gilvum_PYR-GCK RTAAELYRGAPYGVGYFAGVWTP---------------------------
Mvan_2433|M.vanbaalenii_PYR-1 RSAKELYRGAPYGVGYFVGVWTP---------------------------
Mb2747c|M.bovis_AF2122/97 RSAKEFYRGAPHGVGYFAGVWQP---------------------------
Rv2728c|M.tuberculosis_H37Rv RSAKEFYRGAPHGVGYFAGVWQP---------------------------
MLBr_00994|M.leprae_Br4923 RLAKELYRGAPYGVGYFVGVWQP---------------------------
MMAR_1985|M.marinum_M RSATELYRGAPFGVGCFVGVWQP---------------------------
MUL_3371|M.ulcerans_Agy99 RSATELYRGAPFGVGCFVGVWQP---------------------------
MAV_3621|M.avium_104 RSAKELYRGAPYGVGYFAGAWQL---------------------------
MSMEG_2733|M.smegmatis_MC2_155 RTARELYRGVPYGVGYFVGVWVP---------------------------
MAB_3045c|M.abscessus_ATCC_199 VEARCLYRGSPYGVGYFAGIWRVS--------------------------
TH_2716|M.thermoresistible__bu EGATQVFGGIAYTWEHDAHVYLRRTATLAATLGSRARHRRVVTDWLAARG
* .: * .. . :