For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_3800 (-)

MRALLGRWQTWAGFGVAALVLFVLAPAILSDFRLSLLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGL
GGYMMAMHLKIADAQLRGDDVPDFMQIQGIRELPSYWTPFASPAVTLIAIVVIPTGIAVVLGLGVFKRKV
KGAYFAILSQALAAALAILLVGQTSLGGSNGLNRFRTFFGFTLNDPANRRMLYFIAAAVLLLVVAVVRQL
MQSRYGELLVAVRDGEERVRFLGYDPANIKVVAYAVAALFASIAGALFAPIVGFIAPSQVGILPSIAFLI
GVAIGGRATLLGPVLGAIGVAWAQTLFSERFPSAWTYGQGLLFILVVGFLPAGLAGLGVFLKRRRKAEAD
TEPDKASDTDPDAEKVGASS

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_3800	-	-	100% (370)	inner-membrane translocator
M. gilvum PYR-GCK	Mflv_3572	-	1e-20	24.35% (386)	inner-membrane translocator

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_2624c	-	1e-16	23.26% (288)	high-affinity branched-chain amino acid ABC transporter (LivM)
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_2980	-	1e-179	83.73% (375)	hypothetical protein MSMEG_2980
M. thermoresistible (build 8)	TH_2330	-	1e-171	86.17% (347)	putative membrane protein
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_2594	-	0.0	91.89% (370)	inner-membrane translocator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3800|M.gilvum_PYR-GCK          -------MR-ALLGRWQTWAG------FGVAALVLFVLAPAILSDFRLS-
Mvan_2594|M.vanbaalenii_PYR-1       -------MR-TLLGRWQTWAG------FGAAALVLFVVAPAVLSDFRLS-
TH_2330|M.thermoresistible__bu      ---VLDRMPGGVLGRWQTWAG------FGLAALVLFVVAPMVLSDFRLG-
MSMEG_2980|M.smegmatis_MC2_155      -------MR-TMLGRWQTWAG------FAVAAVLLFGVAPAVLSDFRLS-
MAB_2624c|M.abscessus_ATCC_199      MSAARALAPGDSIRRWWSELARPVQWVYGVVGFALLALLPVWKIPYLDTP
                                                : ** :  .      :. ... *: : *     :    

Mflv_3800|M.gilvum_PYR-GCK          ------LLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGLGGYMMAMHL
Mvan_2594|M.vanbaalenii_PYR-1       ------LLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGLGGYMMAMHL
TH_2330|M.thermoresistible__bu      ------LFGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGIGGYLMGMHL
MSMEG_2980|M.smegmatis_MC2_155      ------LLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGLGGYMMGMHL
MAB_2624c|M.abscessus_ATCC_199      NTSFGGVMAQFAMVALIAIGLNVVVGQAGLLDLGYVGFYAIGAYTVAL-L
                                          ::.:*  .*::*:*:.:. *:.*:* **   *:.:*.* :.: *

Mflv_3800|M.gilvum_PYR-GCK          KIADAQLRGDDVPDFMQIQGIRELPSYWTPFASPAVTLIAIVVIPTGIAV
Mvan_2594|M.vanbaalenii_PYR-1       KIADAQLRGDEVPDFMQIQGIRELPGYWAPFASPLVTLIAIVVVPTGIAA
TH_2330|M.thermoresistible__bu      KIADAQIYGTGVPDFMQIAGVRELPGYWEPFASPVVTLAAIVVLPTGIAA
MSMEG_2980|M.smegmatis_MC2_155      KIADAEIRHQAVPDFMQIAGVRELPGYWTPFASPVFTLLAILVIPAGIAA
MAB_2624c|M.abscessus_ATCC_199      TSPDSPWNRMGTSAFFSSD--------WAWLS----CLPIAVAITACFGL
                                    . .*:      .. *:.          *  ::     *   :.:.: :. 

Mflv_3800|M.gilvum_PYR-GCK          VLGLGVFKRKVKGAYFAILSQALAAALAILLVGQTSLGGSNGLNRFR---
Mvan_2594|M.vanbaalenii_PYR-1       ALGLGVFKRKVKGAYFAILSQALAAALAILLVGQTSLGGSNGLNRFR---
TH_2330|M.thermoresistible__bu      ALGFGVFKRRVKGAYFAILSQALAAALAIFLVGQTSLGGSNGLNRFR---
MSMEG_2980|M.smegmatis_MC2_155      LLGLGVFKRRVKGAYFAILSQALAAALAILLVGQTSLGGSNGLNNFR---
MAB_2624c|M.abscessus_ATCC_199      ILGTPTLR--LRGDYLAIVTLGFGEIIRLLADNLDVTNGPRGLHKVAYPH
                                     **  .::  ::* *:**:: .:.  : ::  .    .*..**:..    

Mflv_3800|M.gilvum_PYR-GCK          ----TFFGFTLNDPANRR-------MLYFIAAAVLLLVVAVVRQLMQSRY
Mvan_2594|M.vanbaalenii_PYR-1       ----TFFGFALNDPVNRR-------MLYFIAAAVLLVVVAVVRQLMQSRY
TH_2330|M.thermoresistible__bu      ----TFFGFTLSDPANRR-------MLYFIAAATLLIVVAVARQLMQSRY
MSMEG_2980|M.smegmatis_MC2_155      ----TFFGFTLNDPVNKR-------MLYFIAAATLLIVVAVVRQLMYSRY
MAB_2624c|M.abscessus_ATCC_199      VGEQHVHGGGVFSSANSGGHLNYGVWWYWLGLCLIAAVLVLMGNLERSRV
                                         ..*  : ...*           *::. . :  *:.:  :*  ** 

Mflv_3800|M.gilvum_PYR-GCK          GELLVAVRDGEERVRFLGYDPANIKVVAYAVAALFASIAGALFAPIVGFI
Mvan_2594|M.vanbaalenii_PYR-1       GELLVAVRDGEERVRFLGYDPANIKVVAYAAAALFASIAGALFAPIVGFI
TH_2330|M.thermoresistible__bu      GELLVAVRDNEERVRFLGYDPANVKVVAYTVAALFASIAGALFAPIVGFI
MSMEG_2980|M.smegmatis_MC2_155      GELLVAVRDGEERVRFLGYDPANIKVVAYTLAALFASIAGALFTPIVGFI
MAB_2624c|M.abscessus_ATCC_199      GRSWVAIREDEDAAEMMGVPTFRFKLWAFVIGASIGGLSGALYAGQVQYV
                                    *.  **:*:.*: ..::*  . ..*: *:. .* :..::***::  * ::

Mflv_3800|M.gilvum_PYR-GCK          APSQVGILPSIAFLIGVAIGGRATLLGPVLGAIGVAWAQTLFSERFPSAW
Mvan_2594|M.vanbaalenii_PYR-1       APSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGVAWAQTLFSERFPSEW
TH_2330|M.thermoresistible__bu      APSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGVAWAQTLFSERFPSEW
MSMEG_2980|M.smegmatis_MC2_155      APSQVGIIPSIAFLIGVAIGGRTTLLGPVLGAIGVAWAQTLFSERFPSEW
MAB_2624c|M.abscessus_ATCC_199      ASPTFNIINSMLFLCAVVLGGQGNKLGVVVGAFIIVYLPNRLLGVQVQGI
                                    *.. ..*: *: ** .*.:**: . ** *:**: :.:  . :     .  

Mflv_3800|M.gilvum_PYR-GCK          TYG------QGLLFILVVGFLPAGLAGLGVFLKRRRKAEADTEP-----D
Mvan_2594|M.vanbaalenii_PYR-1       TYA------QGLLFIVVVGFFPAGLAGLGVLLKRRRKAGTEPPP-----E
TH_2330|M.thermoresistible__bu      TYA------QGLLFIVVIGFFPAGLAGLGALRSRLRRRVPDP--------
MSMEG_2980|M.smegmatis_MC2_155      TYA------QGLLFIVVVGFFPAGIAGLGVALRRWRRNKPDPTPPGPDAE
MAB_2624c|M.abscessus_ATCC_199      DLGNLKYLFFGLALVVLMLFRPQGLFPAHQKLMAYWRKTSER--------
                                      .       ** ::::: * * *:           :  .:         

Mflv_3800|M.gilvum_PYR-GCK          KASDTDPDAEKVGASS
Mvan_2594|M.vanbaalenii_PYR-1       KAPDTDPDTEKVGAGS
TH_2330|M.thermoresistible__bu      AVPVKHAQEVKVEAAV
MSMEG_2980|M.smegmatis_MC2_155      PTTDSDPDAEKVGAAS
MAB_2624c|M.abscessus_ATCC_199      -LSAQKPDEVEAGA--
                                      .  ..:  :. *