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VDVVIGQLATGLSLGSILLLAALGLSLTFGQMGVINMAHGEFIMAGCYTAYVVQQVVSNAGVSLILSLVI GFLVGGAMGALLEVTLIQRMYHRPLDTLLVTFGVGLILQQVARDIFGAPAVNVIAPVWLSGGVEIFGAVV PKTRIFILVLAIACVAVLAAVLKVSPMGRRIRAVVQNRDLAETSGISSRKTDITTFFIGSGLAAVAGVAL TLIGSTSPTIGQSYLIDAFLVVVIGGLGQIKGTVIAAFALGFLNSFIEYNTTASLAKVIVFVIIVIVLQV RPQGLFTVRTRSLV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3799 | - | - | 100% (294) | inner-membrane translocator |
| M. gilvum PYR-GCK | Mflv_3573 | - | 1e-26 | 30.13% (302) | inner-membrane translocator |
| M. gilvum PYR-GCK | Mflv_3572 | - | 5e-10 | 23.31% (326) | inner-membrane translocator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_00397 | - | 2e-12 | 23.51% (285) | putative transporter protein |
| M. abscessus ATCC 19977 | MAB_2625c | - | 3e-29 | 30.94% (320) | branched chain amino acid ABC transporter |
| M. marinum M | MMAR_3960 | - | 1e-05 | 27.11% (273) | hypothetical protein MMAR_3960 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2981 | - | 1e-149 | 92.52% (294) | branched-chain amino acid ABC-type transport system, permease |
| M. thermoresistible (build 8) | TH_2329 | - | 1e-145 | 89.76% (293) | branched-chain amino acid ABC-type transport system, permease |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2595 | - | 1e-149 | 92.52% (294) | inner-membrane translocator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2981|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2595|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3799|M.gilvum_PYR-GCK --------------------------------------------------
TH_2329|M.thermoresistible__bu --------------------------------------------------
MAB_2625c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 ---MDHTTKCDAEQYFQAIVTSMADGVIVVDIDGRIESINPAATRILGLR
MMAR_3960|M.marinum_M MTESQHAVISRLSAEFDSLARQMARVSGELSQLDRLISDSVGAPQPAAAA
MSMEG_2981|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2595|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3799|M.gilvum_PYR-GCK --------------------------------------------------
TH_2329|M.thermoresistible__bu --------------------------------------------------
MAB_2625c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 AHDVVDMKHGHPFCFYDTDNQRVDLEREVMRVVRREVTTVSKVVGIDQHS
MMAR_3960|M.marinum_M PPQPQPQPVAPYWYPYWQQWAPVAPAPAAAPPRQYAPPPTARPAPQGPPA
MSMEG_2981|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2595|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3799|M.gilvum_PYR-GCK --------------------------------------------------
TH_2329|M.thermoresistible__bu --------------------------------------------------
MAB_2625c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 GQRLWLSVNVSLLAYKAPPHSALVVSFSDISAHHLSIERLTYEATHDCLT
MMAR_3960|M.marinum_M PAPAAAPPVSAPRRPAESTESGWIGKLLAVAGVAVTLTGVALLLVLAAQA
MSMEG_2981|M.smegmatis_MC2_155 ------------------------------------MDILIGQLATG---
Mvan_2595|M.vanbaalenii_PYR-1 ------------------------------------MDVVIGQLATG---
Mflv_3799|M.gilvum_PYR-GCK ------------------------------------MDVVIGQLATG---
TH_2329|M.thermoresistible__bu ------------------------------------MDILIGQLATG---
MAB_2625c|M.abscessus_ATCC_199 --------------MISGWMAQTGVQASTISFDLHGLWSSIGQLTIDG--
MLBr_00397|M.leprae_Br4923 GLAN--RRFAEDQITKSLQHDERSRLAAVLLLDLDDFKVINDSLGHDVGD
MMAR_3960|M.marinum_M GLLRPEIRVAGGTALSLALVGVAVRLRGRPGGRIGAIALAATGIATAYLD
: :
MSMEG_2981|M.smegmatis_MC2_155 -----------LSLGSILLLAALG----------LSLTFGQMGVINMAHG
Mvan_2595|M.vanbaalenii_PYR-1 -----------LSLGSILLLAALG----------LALTFGQMGVINMAHG
Mflv_3799|M.gilvum_PYR-GCK -----------LSLGSILLLAALG----------LSLTFGQMGVINMAHG
TH_2329|M.thermoresistible__bu -----------LSLGSILLLAALG----------LALTFGQMGVINMAHG
MAB_2625c|M.abscessus_ATCC_199 -----------LAWGAIYALVAVG----------YTLVFGVLRLINFAHS
MLBr_00397|M.leprae_Br4923 AVLQTVAQRLRSAVRPDDVVARLGGD------EFIVLLRGPLSDMNANDV
MMAR_3960|M.marinum_M VIAATTIYQWVPAPAGLVLAALVGGAGLALARRWDSEHLGLLVLVPLIGL
: . :* * : :
MSMEG_2981|M.smegmatis_MC2_155 EFIMAGCYTAYVVQQVIS--------------------------------
Mvan_2595|M.vanbaalenii_PYR-1 EFIMAGCYTAYVVQQLVS--------------------------------
Mflv_3799|M.gilvum_PYR-GCK EFIMAGCYTAYVVQQVVS--------------------------------
TH_2329|M.thermoresistible__bu EFIMVGCYTAYVVQQIVS--------------------------------
MAB_2625c|M.abscessus_ATCC_199 EVFMLGMFGAYFALDVVLGFSPGGN-------------------------
MLBr_00397|M.leprae_Br4923 AKRLHTTLSESLVVDQLTVPIGASVGILEVRPDDRRRAADILRDADSAMY
MMAR_3960|M.marinum_M APVLTRGADLLLVSFMLALSAAALPVQLG-----------------KDWV
: .. :
MSMEG_2981|M.smegmatis_MC2_155 ---SAGASLLIS-LVVGFLVGGAMG-------ALLEVTLIQRMYH-----
Mvan_2595|M.vanbaalenii_PYR-1 ---SAGVSLIIS-LVVGFFIGGAMG-------ALLEVTLIQRMYD-----
Mflv_3799|M.gilvum_PYR-GCK ---NAGVSLILS-LVIGFLVGGAMG-------ALLEVTLIQRMYH-----
TH_2329|M.thermoresistible__bu ---DAGVSLLVS-LFVGFLVGGAMG-------ALLEVTLIRRMYH-----
MAB_2625c|M.abscessus_ATCC_199 -AYNKGVSLTVLYLGVAMLVAMAVS-------ATTALGLEAVAYRPL--R
MLBr_00397|M.leprae_Br4923 AAKNKKQCAVTPQQLVPFVALIALF-------VFFTAAAGAKFYAPSNLL
MMAR_3960|M.marinum_M WLHAARVAAPTVPLLIALVAAGKHDNTWLLGAACGVAAILAIVSGLIVLP
. : :. .
MSMEG_2981|M.smegmatis_MC2_155 ----RPLDTLLVTFGVGLILQQ---------------------IARDIFG
Mvan_2595|M.vanbaalenii_PYR-1 ----RPLDTLLVTFGVGLILQQ---------------------VARDIFG
Mflv_3799|M.gilvum_PYR-GCK ----RPLDTLLVTFGVGLILQQ---------------------VARDIFG
TH_2329|M.thermoresistible__bu ----RPLDTLLVTFGVGLILQQ---------------------VARDIFG
MAB_2625c|M.abscessus_ATCC_199 RRGARPLTFLITAIGMSFVIQE---------------------FVHWVLP
MLBr_00397|M.leprae_Br4923 VILQQTVVLAIVGYGMTFVIMAGSVDLSVGSIVALTGVTAALVAAQNQFA
MMAR_3960|M.marinum_M GGKNAAALAVLTVVGTLPVLAAA-------------------VAVDRVFA
. :. * :: . :
MSMEG_2981|M.smegmatis_MC2_155 APAVN-------------VVAPSWLSGGVEILG------AVVPKTR----
Mvan_2595|M.vanbaalenii_PYR-1 APAVN-------------VVAPEWLSGGVEILG------AVVPKTR----
Mflv_3799|M.gilvum_PYR-GCK APAVN-------------VIAPVWLSGGVEIFG------AVVPKTR----
TH_2329|M.thermoresistible__bu APAVN-------------VLAPAWLGGGVEIFG------AVVPKTR----
MAB_2625c|M.abscessus_ATCC_199 KIAKGYGGSNAQQPLMLVTPRPVWTFGPFDVSGHHIPFQATITNVT----
MLBr_00397|M.leprae_Br4923 AIVTALLVGLAAGMVNGIVFAYGKIPSFVSTLGMLQVCRGITLMISDSSA
MMAR_3960|M.marinum_M ALLAGTLAAALLAIVLVGSELPTIFTRVLAAWSAISALVAVTVAFDG---
. . .
MSMEG_2981|M.smegmatis_MC2_155 ---------------IFILVLAVVCVAVLATVLKASPMGRRIRAVVQNRD
Mvan_2595|M.vanbaalenii_PYR-1 ---------------IFILVLAVVCVAVLAVVLKISPMGRRIRAVVQNRD
Mflv_3799|M.gilvum_PYR-GCK ---------------IFILVLAIACVAVLAAVLKVSPMGRRIRAVVQNRD
TH_2329|M.thermoresistible__bu ---------------LFILVLAVVCVAALAAVLKYSPAGRRIRAVVQNRD
MAB_2625c|M.abscessus_ATCC_199 ---------------VVVVAAALVLAFVTDIAINHTKFGRGIRAVAQDST
MLBr_00397|M.leprae_Br4923 KPMPFHGILGAMGAMPWILIVCLFVTILAGILFQFTMFGRWVKAIGGNER
MMAR_3960|M.marinum_M ---------HVEGPILLALAIVVAIAGRHDRMALWAAAGFGIVGLGLYYS
: : . : * : .:
MSMEG_2981|M.smegmatis_MC2_155 LAETSGISSRKTDITTFFIGSGLAAVAGVALT-LIGSTSPTIGQSFLI--
Mvan_2595|M.vanbaalenii_PYR-1 LAETSGISSRRTDITTFFIGSGLASVAGVALT-LIGSTSPTIGQSYLI--
Mflv_3799|M.gilvum_PYR-GCK LAETSGISSRKTDITTFFIGSGLAAVAGVALT-LIGSTSPTIGQSYLI--
TH_2329|M.thermoresistible__bu LAETSGISSRTTDVTTFFIGSGLAAVAGVALT-LIGSTSPTIGQSYLI--
MAB_2625c|M.abscessus_ATCC_199 TATLMGVSRERIIMATFVIGGLLAGAAALLYT-LKVPQGIIYSGGFLLGI
MLBr_00397|M.leprae_Br4923 VATLAGVPTRGIKVAIFAICGLTAGLGGIVLASRLGAGTPTAATGFEI--
MMAR_3960|M.marinum_M YAPLHALLTATVMPTSIAVSTLAASLLSIAFVVAMSRACAGIGGQNRD-I
* .: : : : *. .: . .
MSMEG_2981|M.smegmatis_MC2_155 DAFLVVVVG--------GLGQIKGTVIAALTLGFLNSFIEYN--------
Mvan_2595|M.vanbaalenii_PYR-1 DAFLVVVVG--------GLGQIKGTVIAAFTLGFLNSFIEYN--------
Mflv_3799|M.gilvum_PYR-GCK DAFLVVVIG--------GLGQIKGTVIAAFALGFLNSFIEYN--------
TH_2329|M.thermoresistible__bu DAFLVVVVG--------GLGQIKGTVIAALGLGFLNSFIEYS--------
MAB_2625c|M.abscessus_ATCC_199 KAFSAAVLG--------GIGNLRGALLGGLILGVMENYGQAV--------
MLBr_00397|M.leprae_Br4923 DVIAAVVIGGTPL--TGGLGRLSGTLIGAIIISMLSNGMVFMGVGN----
MMAR_3960|M.marinum_M RRILAAVGGVLVIYAVTAFTVTAGVLIAGTEAGFLAGHMAATICWIAVAA
: ..* * .: *.::.. ..: .
MSMEG_2981|M.smegmatis_MC2_155 -------------------------TTASLAKVIVFVIIVIFLQVRPQGL
Mvan_2595|M.vanbaalenii_PYR-1 -------------------------TTASLAKVIVFVIIVIFLQARPQGL
Mflv_3799|M.gilvum_PYR-GCK -------------------------TTASLAKVIVFVIIVIVLQVRPQGL
TH_2329|M.thermoresistible__bu -------------------------TTASLAKVIVFALIVIFLQVRPQGL
MAB_2625c|M.abscessus_ATCC_199 -------------------------FGTQWRDVVAFVLLVLVLMFRPTGI
MLBr_00397|M.leprae_Br4923 ------------------------AASQIIKGIMLAAAVFVFLQRRKIGI
MMAR_3960|M.marinum_M ALFVYALRVADRERRTAPIGAGLALTGAATAKLFLFDLATLDGIFRVAAF
:. : * .:
MSMEG_2981|M.smegmatis_MC2_155 FTVRTRSLV-----------
Mvan_2595|M.vanbaalenii_PYR-1 FTVRTRSLV-----------
Mflv_3799|M.gilvum_PYR-GCK FTVRTRSLV-----------
TH_2329|M.thermoresistible__bu FTVRTRSLA-----------
MAB_2625c|M.abscessus_ATCC_199 LGESLGRAKA----------
MLBr_00397|M.leprae_Br4923 IK------------------
MMAR_3960|M.marinum_M IVVGLVLLAMGTGYARSLAR
: