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LDYTHVDGLSAADIARRRELYEPLTASVRDLIDATILTEADPDAVAAAKAEIESATARLRSAARDGSFGI QFGADGESMPWGNAVIGVRNPTAPPLVIHKEPDGFARSDFYLGAAFEGPPGHVHGGVSAKILDHVLGDAA SKPGVHRLTGTITVRYRRLTPLGRLHSEARVTHTDGFKTYAVGHIADATGITVEAEAVFIEPRWARG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3328 | - | - | 100% (208) | thioesterase superfamily protein |
| M. gilvum PYR-GCK | Mflv_2911 | - | 4e-47 | 47.26% (201) | thioesterase superfamily protein |
| M. gilvum PYR-GCK | Mflv_4570 | - | 6e-43 | 50.83% (181) | thioesterase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0363c | - | 8e-06 | 28.35% (194) | hypothetical protein Mb0363c |
| M. tuberculosis H37Rv | Rv0356c | - | 8e-06 | 28.35% (194) | hypothetical protein Rv0356c |
| M. leprae Br4923 | MLBr_00279 | - | 8e-06 | 25.65% (191) | hypothetical protein MLBr_00279 |
| M. abscessus ATCC 19977 | MAB_2901c | - | 5e-06 | 24.55% (110) | hypothetical protein MAB_2901c |
| M. marinum M | MMAR_0247 | - | 5e-58 | 55.22% (201) | hypothetical protein MMAR_0247 |
| M. avium 104 | MAV_2246 | - | 1e-52 | 53.77% (199) | thioesterase family protein |
| M. smegmatis MC2 155 | MSMEG_3571 | - | 3e-70 | 60.19% (206) | thioesterase family protein |
| M. thermoresistible (build 8) | TH_2294 | - | 4e-59 | 55.94% (202) | thioesterase family protein |
| M. ulcerans Agy99 | MUL_4866 | - | 5e-59 | 55.72% (201) | hypothetical protein MUL_4866 |
| M. vanbaalenii PYR-1 | Mvan_3049 | - | 1e-103 | 86.96% (207) | thioesterase superfamily protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3328|M.gilvum_PYR-GCK ---------------MLDYTHVDGLSAADIARRR-ELYEPLTASVRDLID
Mvan_3049|M.vanbaalenii_PYR-1 ---------------MLDYTHVEDLSAADIARLR-AVYEPLTASVRELID
MSMEG_3571|M.smegmatis_MC2_155 ---------------MAGFTHVEGLSSADVQRLR-ATYEPLAQSVRELVD
TH_2294|M.thermoresistible__bu ----------------VVEIQLENLTHAELDRLR-AVYEPLARSVRQLID
MAV_2246|M.avium_104 -----------------MDAIFEVLDAAEAERVT-ALYAPLADAVRELVD
MMAR_0247|M.marinum_M --------------------MSDEWPGTDFDRLE-SVYGPLTASIRRLID
MUL_4866|M.ulcerans_Agy99 --------------------MSDECPGTDFDRLE-SVYGPLTASIRRLID
Mb0363c|M.bovis_AF2122/97 MT-DASVHPDELDP---EYHHHGGFPEYGPASPG-AGFGQFVATMRRLQD
Rv0356c|M.tuberculosis_H37Rv MT-DASVHPDELDP---EYHHHGGFPEYGPASPG-AGFGQFVATMRRLQD
MLBr_00279|M.leprae_Br4923 MTYYSSLRPEDLPPERPKHEHYSGFPEYELANPG-VGFRRFVATMRRLQD
MAB_2901c|M.abscessus_ATCC_199 MTTEEAVTA----------HEGGGFNPPDPTLKGGPDYGRFIDALRTLQD
: : ::* * *
Mflv_3328|M.gilvum_PYR-GCK ATILTEADPDAVAAAKAEIESATARLRSAARDGSFGIQFGADGESMPWGN
Mvan_3049|M.vanbaalenii_PYR-1 ATIRTEVDADAVAAAKAEIDSAAARLRAAQRDGSFGIQFGADGDPMPWGN
MSMEG_3571|M.smegmatis_MC2_155 ATIRSEVDADDVAAAKAHIEAATELLRARQIDGPFGVRITSDGDRMPWGN
TH_2294|M.thermoresistible__bu ATIRTEMDADAVTAATAQIDAVTARLRTRQIDGSFGVRYTTAGAPMAWGD
MAV_2246|M.avium_104 ATIRTEVDDAVVAEARSAIEAVTASLRRRTR--PVGVSYRVDGRPLPLGN
MMAR_0247|M.marinum_M VSIRTQADPATVTASMAKIDSAAEELSDALHPGGFGVQLTPEGETVAWGN
MUL_4866|M.ulcerans_Agy99 VSIRTQADPATVTASMAKIDSAAEELSDALHPGGFGVQLTPEGETVAWGN
Mb0363c|M.bovis_AF2122/97 LAVAADPGDAVWDEAAERAAALVELLS--------PFEADEGKAPAGRTP
Rv0356c|M.tuberculosis_H37Rv LAVAADPGDAVWDEAAERAAALVELLS--------PFEADEGKAPAGRTP
MLBr_00279|M.leprae_Br4923 LAVSADPSDEVWYAAADRAVALVELLG--------PFATDEGKAPAGRVP
MAB_2901c|M.abscessus_ATCC_199 RARAALPPDAVVTELADQLEAMNKLLA--------PYEVSEWDSPSGRRT
: : : *
Mflv_3328|M.gilvum_PYR-GCK AVIGVRNPTAPPLVIHKEPDGFARSDFYLGAAFEGPPGHVHGGVSAKILD
Mvan_3049|M.vanbaalenii_PYR-1 AVIGVRNPCAPPLVIRKEPDGSVKSDFYLGAAFEGPPGHVHGGVSAKILD
MSMEG_3571|M.smegmatis_MC2_155 PAIGIRNAIAPPLRMVRDDDGVMSTDFHLGAAYEGPPGHVHGGIVAMVLD
TH_2294|M.thermoresistible__bu AVCGVRNPIAPPLVTERDGDRVFS-EFELGAAYEGPTGHVHGGVCAMVLD
MAV_2246|M.avium_104 AAIGVCNPIAPPIVVHHEGDGRCWSEFVLGSAYEGPPRLVHGGVSALVLD
MMAR_0247|M.marinum_M VVVGVRNPVAPPLSIHHEPNGLVWSEFTLGAAYEGPPGHVHGGVCSMILD
MUL_4866|M.ulcerans_Agy99 VVVGVRNPVAPPLSIHHEPDGLVWSEFTLGAAYEGPPGHVHGGVCSMILD
Mb0363c|M.bovis_AF2122/97 GLPGMGSLLLPPWTVTRYGTDGVEMRGSFSRFHVGGNSAVHGGVLPLLFD
Rv0356c|M.tuberculosis_H37Rv GLPGMGSLLLPPWTVTRYGTDGVEMRGSFSRFHVGGNSAVHGGVLPLLFD
MLBr_00279|M.leprae_Br4923 DMPGMGSLLLPPWTLTRSGPDSVEMTGYFTRFHVGFNHAVHGGVLPLVFD
MAB_2901c|M.abscessus_ATCC_199 DLPLRGNILLVPMTIESFDNGVLTGTATFGRYHLGRNGAVHGGCLGLLFD
. * : . * **** ::*
Mflv_3328|M.gilvum_PYR-GCK HVLGDAAS-KPGV-HRLTGTITVRYRRLTPLG-RLHSEARVTHTDGFKTY
Mvan_3049|M.vanbaalenii_PYR-1 HILGDAAS-TPGV-HRLTGTITVRYRRLTPLG-RLRSEARVTHTDGFKTY
MSMEG_3571|M.smegmatis_MC2_155 HVLGEVAANDPLT-PRFTGTLTIRYLRATPLG-DLRAEGWITRTDGIKTF
TH_2294|M.thermoresistible__bu HLLGEVAA-DSDK-PRFTGTLTVRYRRPTPLG-ALRAEAWIDRIDGPKAF
MAV_2246|M.avium_104 HMLGEAASEGLSK-ARFTGTITVKYLRGTPLG-PLRCDAWIDRREGVKVF
MMAR_0247|M.marinum_M HVLGATAH-LPRR-PAYTGTLTLRYRRGTVLGRPLRAEGRVERIEGVKTF
MUL_4866|M.ulcerans_Agy99 HVLGATAH-LPRR-PAYTGTLTLRYRRGTVLGRPLRAEGRVERIEGVKTF
Mb0363c|M.bovis_AF2122/97 HMFGMISHAAGRP-ISRTAFLHVDYRRITPIDVPLIVRGRVTNTEGRKAF
Rv0356c|M.tuberculosis_H37Rv HMFGMISHAAGRP-ISRTAFLHVDYRRITPIDVPLIVRGRVTNTEGRKAF
MLBr_00279|M.leprae_Br4923 HLFGMISYTAGRS-ISRTAFLHVDYRKITPIDEPLVMRGRVTRTEGRKAF
MAB_2901c|M.abscessus_ATCC_199 TIFGTGSLLLTDLRKLRTAYLNINYRKITPIEKELRYDCTLARVEGRKVF
::* : *. : : * : * : * : . :* *.:
Mflv_3328|M.gilvum_PYR-GCK AVGHIADATG-ITVEAEAVFIEPRWARG--
Mvan_3049|M.vanbaalenii_PYR-1 AVGHIADSTG-VTVDAEAVFIEPKWARD--
MSMEG_3571|M.smegmatis_MC2_155 AVGHVRDAAG-ITAEAEGVFIPPKWARG--
TH_2294|M.thermoresistible__bu AAGHILAGQQ-VTAEAEGVFILPKWARG--
MAV_2246|M.avium_104 ARGIISDAAG-VTVEADGVFIEPAWARETQ
MMAR_0247|M.marinum_M SVGHIADENG-ITVEAEGIFIQSKQIRA--
MUL_4866|M.ulcerans_Agy99 SVGHIADESG-ITVEAEGIFIQSKQIRA--
Mb0363c|M.bovis_AF2122/97 VCAELFDSDETLLAEGNGLMVRLLPGQP--
Rv0356c|M.tuberculosis_H37Rv VCAELFDSDETLLAEGNGLMVRLLPGQP--
MLBr_00279|M.leprae_Br4923 VSAELVDGDEMLLAEGNGMMVRLLAGQP--
MAB_2901c|M.abscessus_ATCC_199 MTGRLLDGDE-VLAEADALFVKLNPGQP--
. : : .:.:.::: :