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VFEYDKISADDYDRLRGRYEPLTDALRTLVDVGVHTDVDDATVREALVHLEAATALLQQRLREDRPVLRH ADTGRPVTWGNPAVGLRNAISPPIVVEHDGDGRCWSEFTLGPVYEGPPGWVHGGVSALVLDQILGEVASD SLSKARFTGTISLRYVRGTPLGPLRAEAFVERTEGAKTFAKGYLMDADGVTVEAEGVFITPAWARDAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2911 | - | - | 100% (208) | thioesterase superfamily protein |
| M. gilvum PYR-GCK | Mflv_3328 | - | 4e-47 | 47.26% (201) | thioesterase superfamily protein |
| M. gilvum PYR-GCK | Mflv_4570 | - | 1e-33 | 41.99% (181) | thioesterase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0363c | - | 6e-08 | 28.90% (173) | hypothetical protein Mb0363c |
| M. tuberculosis H37Rv | Rv0356c | - | 6e-08 | 28.90% (173) | hypothetical protein Rv0356c |
| M. leprae Br4923 | MLBr_00279 | - | 1e-05 | 36.36% (77) | hypothetical protein MLBr_00279 |
| M. abscessus ATCC 19977 | MAB_2901c | - | 4e-12 | 32.80% (186) | hypothetical protein MAB_2901c |
| M. marinum M | MMAR_3292 | - | 2e-54 | 51.22% (205) | hypothetical protein MMAR_3292 |
| M. avium 104 | MAV_2246 | - | 3e-65 | 58.82% (204) | thioesterase family protein |
| M. smegmatis MC2 155 | MSMEG_3571 | - | 2e-55 | 51.76% (199) | thioesterase family protein |
| M. thermoresistible (build 8) | TH_2294 | - | 4e-52 | 49.26% (203) | thioesterase family protein |
| M. ulcerans Agy99 | MUL_4866 | - | 1e-48 | 47.96% (196) | hypothetical protein MUL_4866 |
| M. vanbaalenii PYR-1 | Mvan_3596 | - | 3e-94 | 76.33% (207) | hypothetical protein Mvan_3596 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2911|M.gilvum_PYR-GCK -----------------MFEYD-KISADDYDRLR-GRYEPLTDALRTLVD
Mvan_3596|M.vanbaalenii_PYR-1 ----------------MDFTFE-AISAEEYDRQR-ASYEPLTDALRRLID
MMAR_3292|M.marinum_M ----------------MGAAFEGSSDDAELDRVE-ATYAPLAEAVRDLID
MAV_2246|M.avium_104 ----------------MDAIFE-VLDAAEAERVT-ALYAPLADAVRELVD
MSMEG_3571|M.smegmatis_MC2_155 ---------------MAGFTHVEGLSSADVQRLR-ATYEPLAQSVRELVD
TH_2294|M.thermoresistible__bu ----------------VVEIQLENLTHAELDRLR-AVYEPLARSVRQLID
MUL_4866|M.ulcerans_Agy99 --------------------MSDECPGTDFDRLE-SVYGPLTASIRRLID
Mb0363c|M.bovis_AF2122/97 MT-DASVHPDELDP---EYHHHGGFPEYGPASPG-AGFGQFVATMRRLQD
Rv0356c|M.tuberculosis_H37Rv MT-DASVHPDELDP---EYHHHGGFPEYGPASPG-AGFGQFVATMRRLQD
MLBr_00279|M.leprae_Br4923 MTYYSSLRPEDLPPERPKHEHYSGFPEYELANPG-VGFRRFVATMRRLQD
MAB_2901c|M.abscessus_ATCC_199 MTTEEAVTA----------HEGGGFNPPDPTLKGGPDYGRFIDALRTLQD
: : ::* * *
Mflv_2911|M.gilvum_PYR-GCK VGVHTDVDDATVREALVHLEAATALLQQRLREDRPVLRHADTGRPVTWGN
Mvan_3596|M.vanbaalenii_PYR-1 VGIHTEVDDATVQQALTHLAAAEELLGRQQRSGRSTLRHADTGRPVAWAN
MMAR_3292|M.marinum_M ATIQTRADEEGILQARAVIEAVTQSLRREQSRPCEVSYRGD-ARPIPLAN
MAV_2246|M.avium_104 ATIRTEVDDAVVAEARSAIEAVTASLRR-RTRPVGVSYRVD-GRPLPLGN
MSMEG_3571|M.smegmatis_MC2_155 ATIRSEVDADDVAAAKAHIEAATELLRARQIDGPFGVRITSDGDRMPWGN
TH_2294|M.thermoresistible__bu ATIRTEMDADAVTAATAQIDAVTARLRTRQIDGSFGVRYTTAGAPMAWGD
MUL_4866|M.ulcerans_Agy99 VSIRTQADPATVTASMAKIDSAAEELSDALHPGGFGVQLTPEGETVAWGN
Mb0363c|M.bovis_AF2122/97 LAVAADPGDAVWDEAAERAAALVELLSPFEADEG--------KAPAGRTP
Rv0356c|M.tuberculosis_H37Rv LAVAADPGDAVWDEAAERAAALVELLSPFEADEG--------KAPAGRTP
MLBr_00279|M.leprae_Br4923 LAVSADPSDEVWYAAADRAVALVELLGPFATDEG--------KAPAGRVP
MAB_2901c|M.abscessus_ATCC_199 RARAALPPDAVVTELADQLEAMNKLLAPYEVSEW--------DSPSGRRT
: : *
Mflv_2911|M.gilvum_PYR-GCK PAVGLRNAISPPIVVEHD---GDGRCWSEFTLGPVYEGPPGWVHGGVSAL
Mvan_3596|M.vanbaalenii_PYR-1 PAVGLRNAIAPPMRIEHE---PDGTCWSEFTLGPAYEGPPGWVHGGIAAL
MMAR_3292|M.marinum_M AVIGQCNPIAPPVVVHHDPDAADGRCRAEFVLGAAYEGPPGLVHGGVCAL
MAV_2246|M.avium_104 AAIGVCNPIAPPIVVHHE---GDGRCWSEFVLGSAYEGPPRLVHGGVSAL
MSMEG_3571|M.smegmatis_MC2_155 PAIGIRNAIAPPLRMVRD---DDGVMSTDFHLGAAYEGPPGHVHGGIVAM
TH_2294|M.thermoresistible__bu AVCGVRNPIAPPLVTERD---GDRVFS-EFELGAAYEGPTGHVHGGVCAM
MUL_4866|M.ulcerans_Agy99 VVVGVRNPVAPPLSIHHE---PDGLVWSEFTLGAAYEGPPGHVHGGVCSM
Mb0363c|M.bovis_AF2122/97 GLPGMGSLLLPPWTVTRY---GTDGVEMRGSFSRFHVGGNSAVHGGVLPL
Rv0356c|M.tuberculosis_H37Rv GLPGMGSLLLPPWTVTRY---GTDGVEMRGSFSRFHVGGNSAVHGGVLPL
MLBr_00279|M.leprae_Br4923 DMPGMGSLLLPPWTLTRS---GPDSVEMTGYFTRFHVGFNHAVHGGVLPL
MAB_2901c|M.abscessus_ATCC_199 DLPLRGNILLVPMTIESF---DNGVLTGTATFGRYHLGRNGAVHGGCLGL
. : * : : * **** :
Mflv_2911|M.gilvum_PYR-GCK VLDQILGEVASDSLSK-ARFTGTISLRYVRGTPLG-PLRAEAFVERTEGA
Mvan_3596|M.vanbaalenii_PYR-1 VLDHLLGEVASDGLTQ-PRFTGTISLRYLRGTPLG-PLRAEAFVERSEGA
MMAR_3292|M.marinum_M VLDHLLGEAASQGRTQ-PLFTGTITVKYLRGTPLG-PLRCEAWVDRTEGV
MAV_2246|M.avium_104 VLDHMLGEAASEGLSK-ARFTGTITVKYLRGTPLG-PLRCDAWIDRREGV
MSMEG_3571|M.smegmatis_MC2_155 VLDHVLGEVAANDPLT-PRFTGTLTIRYLRATPLG-DLRAEGWITRTDGI
TH_2294|M.thermoresistible__bu VLDHLLGEVAA-DSDK-PRFTGTLTVRYRRPTPLG-ALRAEAWIDRIDGP
MUL_4866|M.ulcerans_Agy99 ILDHVLG-ATAHLPRR-PAYTGTLTLRYRRGTVLGRPLRAEGRVERIEGV
Mb0363c|M.bovis_AF2122/97 LFDHMFGMISHAAGRP-ISRTAFLHVDYRRITPIDVPLIVRGRVTNTEGR
Rv0356c|M.tuberculosis_H37Rv LFDHMFGMISHAAGRP-ISRTAFLHVDYRRITPIDVPLIVRGRVTNTEGR
MLBr_00279|M.leprae_Br4923 VFDHLFGMISYTAGRS-ISRTAFLHVDYRKITPIDEPLVMRGRVTRTEGR
MAB_2901c|M.abscessus_ATCC_199 LFDTIFGTGSLLLTDLRKLRTAYLNINYRKITPIEKELRYDCTLARVEGR
::* ::* : *. : : * : * : * : . :*
Mflv_2911|M.gilvum_PYR-GCK KTFAKGYLMDADG-VTVEAEGVFITPAWARDAG
Mvan_3596|M.vanbaalenii_PYR-1 KTFARGYLMDADG-VTVEADGVFITPAWARDAG
MMAR_3292|M.marinum_M KAFARGFLSDAEG-ITAQAEGVFIKPAWAREVP
MAV_2246|M.avium_104 KVFARGIISDAAG-VTVEADGVFIEPAWARETQ
MSMEG_3571|M.smegmatis_MC2_155 KTFAVGHVRDAAG-ITAEAEGVFIPPKWARG--
TH_2294|M.thermoresistible__bu KAFAAGHILAGQQ-VTAEAEGVFILPKWARG--
MUL_4866|M.ulcerans_Agy99 KTFSVGHIADESG-ITVEAEGIFIQSKQIRA--
Mb0363c|M.bovis_AF2122/97 KAFVCAELFDSDETLLAEGNGLMVRLLPGQP--
Rv0356c|M.tuberculosis_H37Rv KAFVCAELFDSDETLLAEGNGLMVRLLPGQP--
MLBr_00279|M.leprae_Br4923 KAFVSAELVDGDEMLLAEGNGMMVRLLAGQP--
MAB_2901c|M.abscessus_ATCC_199 KVFMTGRLLDGDE-VLAEADALFVKLNPGQP--
*.* . : : .:.:.::: :