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LDYTHVEDLSAADIARLRAVYEPLTASVRELIDATIRTEVDADAVAAAKAEIDSAAARLRAAQRDGSFGI QFGADGDPMPWGNAVIGVRNPCAPPLVIRKEPDGSVKSDFYLGAAFEGPPGHVHGGVSAKILDHILGDAA STPGVHRLTGTITVRYRRLTPLGRLRSEARVTHTDGFKTYAVGHIADSTGVTVDAEAVFIEPKWARD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3049 | - | - | 100% (208) | thioesterase superfamily protein |
| M. vanbaalenii PYR-1 | Mvan_3596 | - | 4e-50 | 49.04% (208) | hypothetical protein Mvan_3596 |
| M. vanbaalenii PYR-1 | Mvan_2864 | - | 1e-38 | 42.35% (196) | thioesterase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0363c | - | 3e-06 | 27.43% (175) | hypothetical protein Mb0363c |
| M. gilvum PYR-GCK | Mflv_3328 | - | 1e-103 | 86.96% (207) | thioesterase superfamily protein |
| M. tuberculosis H37Rv | Rv0356c | - | 4e-06 | 27.43% (175) | hypothetical protein Rv0356c |
| M. leprae Br4923 | MLBr_00279 | - | 3e-07 | 25.26% (190) | hypothetical protein MLBr_00279 |
| M. abscessus ATCC 19977 | MAB_4248c | - | 1e-05 | 26.13% (111) | hypothetical protein MAB_4248c |
| M. marinum M | MMAR_0247 | - | 1e-58 | 55.22% (201) | hypothetical protein MMAR_0247 |
| M. avium 104 | MAV_2246 | - | 4e-54 | 53.96% (202) | thioesterase family protein |
| M. smegmatis MC2 155 | MSMEG_3571 | - | 2e-73 | 62.44% (205) | thioesterase family protein |
| M. thermoresistible (build 8) | TH_2294 | - | 4e-65 | 61.19% (201) | thioesterase family protein |
| M. ulcerans Agy99 | MUL_4866 | - | 1e-59 | 55.72% (201) | hypothetical protein MUL_4866 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3049|M.vanbaalenii_PYR-1 -----------------------------------------MLDYTHVED
Mflv_3328|M.gilvum_PYR-GCK -----------------------------------------MLDYTHVDG
MSMEG_3571|M.smegmatis_MC2_155 -----------------------------------------MAGFTHVEG
TH_2294|M.thermoresistible__bu ------------------------------------------VVEIQLEN
MAV_2246|M.avium_104 -------------------------------------------MDAIFEV
MMAR_0247|M.marinum_M ----------------------------------------------MSDE
MUL_4866|M.ulcerans_Agy99 ----------------------------------------------MSDE
Mb0363c|M.bovis_AF2122/97 ---------------------MT-----DASVHPDELDP----EYHHHGG
Rv0356c|M.tuberculosis_H37Rv ---------------------MT-----DASVHPDELDP----EYHHHGG
MLBr_00279|M.leprae_Br4923 ---------------------MTY----YSSLRPEDLPPE-RPKHEHYSG
MAB_4248c|M.abscessus_ATCC_199 MHWRRAGPGSNDREAGHTLAVMTADGDRLAALHEEMNRAIREIDGEHSGG
Mvan_3049|M.vanbaalenii_PYR-1 LSAADIARLRAVYEPLTASVRELIDATIRTEVDADAVAAAKAEIDSAAAR
Mflv_3328|M.gilvum_PYR-GCK LSAADIARRRELYEPLTASVRDLIDATILTEADPDAVAAAKAEIESATAR
MSMEG_3571|M.smegmatis_MC2_155 LSSADVQRLRATYEPLAQSVRELVDATIRSEVDADDVAAAKAHIEAATEL
TH_2294|M.thermoresistible__bu LTHAELDRLRAVYEPLARSVRQLIDATIRTEMDADAVTAATAQIDAVTAR
MAV_2246|M.avium_104 LDAAEAERVTALYAPLADAVRELVDATIRTEVDDAVVAEARSAIEAVTAS
MMAR_0247|M.marinum_M WPGTDFDRLESVYGPLTASIRRLIDVSIRTQADPATVTASMAKIDSAAEE
MUL_4866|M.ulcerans_Agy99 CPGTDFDRLESVYGPLTASIRRLIDVSIRTQADPATVTASMAKIDSAAEE
Mb0363c|M.bovis_AF2122/97 FPEYGPASPGAGFGQFVATMRRLQDLAVAADPGDAVWDEAAERAAALVEL
Rv0356c|M.tuberculosis_H37Rv FPEYGPASPGAGFGQFVATMRRLQDLAVAADPGDAVWDEAAERAAALVEL
MLBr_00279|M.leprae_Br4923 FPEYELANPGVGFRRFVATMRRLQDLAVSADPSDEVWYAAADRAVALVEL
MAB_4248c|M.abscessus_ATCC_199 FPQYSPSSVGPGFGRFLTAMRRLQDLAVSADMDDPRWDEAADLTEKLVEL
: : ::* * * :: :: . : .
Mvan_3049|M.vanbaalenii_PYR-1 LRAAQRDGSFGIQFGADGDPMPWGNAVIGVRNPCAPPLVIRKEPDGSVKS
Mflv_3328|M.gilvum_PYR-GCK LRSAARDGSFGIQFGADGESMPWGNAVIGVRNPTAPPLVIHKEPDGFARS
MSMEG_3571|M.smegmatis_MC2_155 LRARQIDGPFGVRITSDGDRMPWGNPAIGIRNAIAPPLRMVRDDDGVMST
TH_2294|M.thermoresistible__bu LRTRQIDGSFGVRYTTAGAPMAWGDAVCGVRNPIAPPLVTERDGDRVFS-
MAV_2246|M.avium_104 LRRRTR--PVGVSYRVDGRPLPLGNAAIGVCNPIAPPIVVHHEGDGRCWS
MMAR_0247|M.marinum_M LSDALHPGGFGVQLTPEGETVAWGNVVVGVRNPVAPPLSIHHEPNGLVWS
MUL_4866|M.ulcerans_Agy99 LSDALHPGGFGVQLTPEGETVAWGNVVVGVRNPVAPPLSIHHEPDGLVWS
Mb0363c|M.bovis_AF2122/97 LSPFEADEGKAPAGRTPGLP--------GMGSLLLPPWTVTRYGTDGVEM
Rv0356c|M.tuberculosis_H37Rv LSPFEADEGKAPAGRTPGLP--------GMGSLLLPPWTVTRYGTDGVEM
MLBr_00279|M.leprae_Br4923 LGPFATDEGKAPAGRVPDMP--------GMGSLLLPPWTLTRSGPDSVEM
MAB_4248c|M.abscessus_ATCC_199 MDPFEAPEGVGPANRVADEP--------ANGHLLLPPWFIDKAGPDGIEA
: . . . ** :
Mvan_3049|M.vanbaalenii_PYR-1 DFYLGAAFEGPPGHVHGGVSAKILDHILGDAAS-TPGVHRLTGTITVRYR
Mflv_3328|M.gilvum_PYR-GCK DFYLGAAFEGPPGHVHGGVSAKILDHVLGDAAS-KPGVHRLTGTITVRYR
MSMEG_3571|M.smegmatis_MC2_155 DFHLGAAYEGPPGHVHGGIVAMVLDHVLGEVAANDPLTPRFTGTLTIRYL
TH_2294|M.thermoresistible__bu EFELGAAYEGPTGHVHGGVCAMVLDHLLGEVAA-DSDKPRFTGTLTVRYR
MAV_2246|M.avium_104 EFVLGSAYEGPPRLVHGGVSALVLDHMLGEAASEGLSKARFTGTITVKYL
MMAR_0247|M.marinum_M EFTLGAAYEGPPGHVHGGVCSMILDHVLGATAH-LPRRPAYTGTLTLRYR
MUL_4866|M.ulcerans_Agy99 EFTLGAAYEGPPGHVHGGVCSMILDHVLGATAH-LPRRPAYTGTLTLRYR
Mb0363c|M.bovis_AF2122/97 RGSFSRFHVGGNSAVHGGVLPLLFDHMFGMISHAAGRPISRTAFLHVDYR
Rv0356c|M.tuberculosis_H37Rv RGSFSRFHVGGNSAVHGGVLPLLFDHMFGMISHAAGRPISRTAFLHVDYR
MLBr_00279|M.leprae_Br4923 TGYFTRFHVGFNHAVHGGVLPLVFDHLFGMISYTAGRSISRTAFLHVDYR
MAB_4248c|M.abscessus_ATCC_199 HGDFPRFYLGGNGAVHGGILPLLFDHLFGMTVIMAGRTISRTAFLHVNYR
: . * ****: . ::**::* *. : : *
Mvan_3049|M.vanbaalenii_PYR-1 RLTPLG-RLRSEARVTHTDGFKTYAVGHIADS-TGVTVDAEAVFIEPKWA
Mflv_3328|M.gilvum_PYR-GCK RLTPLG-RLHSEARVTHTDGFKTYAVGHIADA-TGITVEAEAVFIEPRWA
MSMEG_3571|M.smegmatis_MC2_155 RATPLG-DLRAEGWITRTDGIKTFAVGHVRDA-AGITAEAEGVFIPPKWA
TH_2294|M.thermoresistible__bu RPTPLG-ALRAEAWIDRIDGPKAFAAGHILAG-QQVTAEAEGVFILPKWA
MAV_2246|M.avium_104 RGTPLG-PLRCDAWIDRREGVKVFARGIISDA-AGVTVEADGVFIEPAWA
MMAR_0247|M.marinum_M RGTVLGRPLRAEGRVERIEGVKTFSVGHIADE-NGITVEAEGIFIQSKQI
MUL_4866|M.ulcerans_Agy99 RGTVLGRPLRAEGRVERIEGVKTFSVGHIADE-SGITVEAEGIFIQSKQI
Mb0363c|M.bovis_AF2122/97 RITPIDVPLIVRGRVTNTEGRKAFVCAELFDSDETLLAEGNGLMVRLLPG
Rv0356c|M.tuberculosis_H37Rv RITPIDVPLIVRGRVTNTEGRKAFVCAELFDSDETLLAEGNGLMVRLLPG
MLBr_00279|M.leprae_Br4923 KITPIDEPLVMRGRVTRTEGRKAFVSAELVDGDEMLLAEGNGMMVRLLAG
MAB_4248c|M.abscessus_ATCC_199 QVVPVGVPLTASSRIDEVDRRKAFVSAELCDAHGVVLADANGLMVQLLPG
: . :. * . : . : *.: . : : .:.:.:::
Mvan_3049|M.vanbaalenii_PYR-1 RD--
Mflv_3328|M.gilvum_PYR-GCK RG--
MSMEG_3571|M.smegmatis_MC2_155 RG--
TH_2294|M.thermoresistible__bu RG--
MAV_2246|M.avium_104 RETQ
MMAR_0247|M.marinum_M RA--
MUL_4866|M.ulcerans_Agy99 RA--
Mb0363c|M.bovis_AF2122/97 QP--
Rv0356c|M.tuberculosis_H37Rv QP--
MLBr_00279|M.leprae_Br4923 QP--
MAB_4248c|M.abscessus_ATCC_199 QP--
: