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VPSSSGPAEPADLPTFLAAHTPFQGSTAEELAELAVGAQLETFPAAAVVADYSARVPDEVWMVRDGAVAL RSSGDGALIDVVTAGGIFGYLPLLTGAGADFEARTTSPSTLVRLPGAAVRAQFAKPSGLAFLASAGWNRP ADRPTIAPATDSRPVAELVAGGVLLVAPGDPVRDVVVQMTDHHVSYALIRLPDGRLGIFTDRDLRIRVVA AGLPVDVAVDRVMSAPARTVTADMTADSVLMEMLECGLRHMPVLTPRGEVIGVLEDADLLAATARQSFLL RRSIGQASDAAQLQQVGQRVTATAVDLFRNGTNAAATSAILSVVIDSLVRRSLELVLAQPENAGVGGFAW LTLGSVARREAMPSSDVDSALSWRDDLDGEAPRLRGIAADVHHILDGCGLPADSNGAIATTTAFARSQSD WRRAAQGWVDEPLRNLGLIMSSLLLDARVVWGEVGLHTAPAAYQRIREKNPEALRLQLLDALAGKMRTRS LRDVLSRRGGTFDLKNHALAPIVNLARWGGLSAGVTSASTPARLAAAAQAGVLRDADSRTLCDVFAMVQR LRLAHQVEQISAGHPPGDIITMSELSPLNRSLLGDGLREIAAVRRRVGSAGLTGI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3086 | - | - | 100% (615) | cyclic nucleotide-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2708 | - | 3e-38 | 31.93% (332) | hypothetical protein MAB_2708 |
| M. marinum M | MMAR_3726 | - | 8e-05 | 24.77% (109) | transcriptional regulator |
| M. avium 104 | MAV_1776 | - | 1e-05 | 25.69% (109) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2183 | - | 4e-28 | 29.52% (332) | hypothetical protein MSMEG_2183 |
| M. thermoresistible (build 8) | TH_4428 | - | 7e-07 | 23.37% (184) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3669 | - | 9e-05 | 24.77% (109) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3907 | - | 2e-06 | 28.18% (110) | signal-transduction protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2183|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3086|M.gilvum_PYR-GCK MPSSSGPAEPADLPTFLAAHTPFQGSTAEELAELAVGAQLETFPAAAVVA
TH_4428|M.thermoresistible__bu --------------------------------------------------
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2183|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3086|M.gilvum_PYR-GCK DYSARVPDEVWMVRDGAVALRSSGDGALIDVVTAGGIFGYLPLLTGAGAD
TH_4428|M.thermoresistible__bu --------------------------------------------------
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2183|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3086|M.gilvum_PYR-GCK FEARTTSPSTLVRLPGAAVRAQFAKPSGLAFLASAGWNRPADRPTIAPAT
TH_4428|M.thermoresistible__bu --------------------------------------------------
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2183|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3086|M.gilvum_PYR-GCK DSRPVAELVAGGVLLVAPGDPVRDVVVQMTDHHVSYALIRLPDGRLGIFT
TH_4428|M.thermoresistible__bu --------------------------------------------------
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2183|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3086|M.gilvum_PYR-GCK DRDLRIRVVAAGLPVDVAVDRVMSAPARTVTADMTADSVLMEMLECGLRH
TH_4428|M.thermoresistible__bu --------------------------------------------------
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 -------------------MSAEVPAENGMARAIAQIDAAADEAAFHAGV
MSMEG_2183|M.smegmatis_MC2_155 -----------------------------MQR---HIDAATSVAGLRAAT
Mflv_3086|M.gilvum_PYR-GCK MPVLTPRGEVIGVLEDADLLAATARQSFLLRRSIGQASDAAQLQQVGQRV
TH_4428|M.thermoresistible__bu --------------------------------------------------
MMAR_3726|M.marinum_M ----------------------MRIADVLRNKGAAVTTIN----------
MUL_3669|M.ulcerans_Agy99 ----------------------MRIADVLRNKGAVVTTIN----------
MAV_1776|M.avium_104 ----------------------MRIADVLRNKGAAVVTIN----------
Mvan_3907|M.vanbaalenii_PYR-1 ----------------------MRISDVLRNKGATVATIT----------
MAB_2708|M.abscessus_ATCC_1997 SATRIAITLQ-ARARAPEATLAAAWSEALRSSVITAARLVTDGVNPGWSW
MSMEG_2183|M.smegmatis_MC2_155 AELPAAAREL-VGARA--ATVAHAWSALLRAALRTAARVT--GPAPG-TW
Mflv_3086|M.gilvum_PYR-GCK TATAVDLFRNGTNAAATSAILSVVIDSLVRRSLELVLAQPENAGVGGFAW
TH_4428|M.thermoresistible__bu ----VVLNPNDPILEAARAIEENRIGAVVIQKGGRLVGIVT---------
:
MMAR_3726|M.marinum_M ------------PDATVRELLAG-----------LAEQNIGAMVVVGVEG
MUL_3669|M.ulcerans_Agy99 ------------PDATVRELFAG-----------LAEQNIGAMVVVGVEG
MAV_1776|M.avium_104 ------------PDATVRELIAG-----------LTEQNIGAMVVVGAEG
Mvan_3907|M.vanbaalenii_PYR-1 ------------PETSVAGLLTE-----------LSVHNIGAMVVVSPDG
MAB_2708|M.abscessus_ATCC_1997 FVSGSAARGEAAPGSDIETLIAVDDTIDAEGKTRLMELAARVHTTLERGG
MSMEG_2183|M.smegmatis_MC2_155 YASGSVGRGEALPGSDLDTLFVRDEGTPVD---AALHHALEVHDLLSACG
Mflv_3086|M.gilvum_PYR-GCK LTLGSVARREAMPSSDVDSALSWRDDLDGEAP-RLRGIAADVHHILDGCG
TH_4428|M.thermoresistible__bu -----------DRDLAVRALGRGLDPN----TTKIAEVMTESPITLTPRD
: : .
MMAR_3726|M.marinum_M VVG----IVSERDVVRQLHTHGASVLTRPVS-------KIMTSAVATCT-
MUL_3669|M.ulcerans_Agy99 VVG----IVSERDVVRQLHTHGASVLTRPVS-------KIMTSAVATCT-
MAV_1776|M.avium_104 VLG----IVSERDVVRQLHVHGASVLSRPVS-------KIMTTTLATCT-
Mvan_3907|M.vanbaalenii_PYR-1 LLG----IVSERDVVRKLHDMGADLLRRPVS-------EIMSTLVATCT-
MAB_2708|M.abscessus_ATCC_1997 IGGDSNGVLASRGRFCRRTTDWLEGIERWCANPPADRGVVMAGLMADSRG
MSMEG_2183|M.smegmatis_MC2_155 IPGDEKGVTAARARFNRSASQWEDGIARWAGDAAADRGVVMIGLLADA--
Mflv_3086|M.gilvum_PYR-GCK LPADSNGAIATTTAFARSQSDWRRAAQGWVDEPLRNLGLIMSSLLLDAR-
TH_4428|M.thermoresistible__bu STDDAIRLMRERNIRRIPLVEHDRVVGMVTLD------DLILDEAAPLEE
::
MMAR_3726|M.marinum_M ----KSDTVDSISVLMTQNRVR-HVPVLDGQKLIGIVSIGDVVKSRMGEL
MUL_3669|M.ulcerans_Agy99 ----KSDTVDSISVLMTQNRVR-HVPVLDGQKLIGIVSIGDVVKSRMGEL
MAV_1776|M.avium_104 ----KTDTVDEISVLMTRNRVR-HVPVLDGKKLIGIVSIGDVVKTRMEEL
Mvan_3907|M.vanbaalenii_PYR-1 ----PDDTVDSLSALMTNNRVR-HVPVVVDGRLAGIVSIGDVVKTRMEEL
MAB_2708|M.abscessus_ATCC_1997 VGADASLPDGALRSKNARCAQR-HYP-IRHAMLQDAVAVRAGFPSRLKIF
MSMEG_2183|M.smegmatis_MC2_155 ----FPLTDGPDLAARARTAVG-DHPDALAAMLQDATYLRAHVPSRLRVL
Mflv_3086|M.gilvum_PYR-GCK ---VVWGEVGLHTAPAAYQRIREKNPEALRLQLLDALAGKMRTRSLRDVL
TH_4428|M.thermoresistible__bu LAAIVEAQIGEGGPADSDRSPARRRRLVRAEATLNRLVKQVQEDAGLEDA
. : . :
MMAR_3726|M.marinum_M EAEQEQLQSYITQG------------------------------------
MUL_3669|M.ulcerans_Agy99 EAEQEQLQSYITQG------------------------------------
MAV_1776|M.avium_104 EAEQQQLQSYITQG------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 EREQQHLQAYITQG------------------------------------
MAB_2708|M.abscessus_ATCC_1997 ATQSDSVDLKITAMDPVVKIARWAALSAGSDVLATPARLDAASTAETLDR
MSMEG_2183|M.smegmatis_MC2_155 ATRDTAVDLKAATIDPVVRITRWAALCCGSSERGTPDRIHDAAGGRFLDD
Mflv_3086|M.gilvum_PYR-GCK SRRGGTFDLKNHALAPIVNLARWGGLSAGVTSASTPARLAAAAQAGVLRD
TH_4428|M.thermoresistible__bu DQARAALDIVVGALVRRLTPGEAKDFISQLPSLLKPHLQTLPPGPD--RS
.:
MMAR_3726|M.marinum_M --------------------------------------------------
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
MAV_1776|M.avium_104 --------------------------------------------------
Mvan_3907|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2708|M.abscessus_ATCC_1997 DDASTLHDCFDWLLRFRWRARAAAWEE-GQPMSDTVSLSALAPQERAMLR
MSMEG_2183|M.smegmatis_MC2_155 EDAAVLTRCHAIGSSIRWRTRADQITSSGGEITDHVAMSAFSPQDRTALR
Mflv_3086|M.gilvum_PYR-GCK ADSRTLCDVFAMVQRLRLAHQVEQISAGHPPG-DIITMSELSPLNRSLLG
TH_4428|M.thermoresistible__bu VTRESIEGDLVARLGVDQSRATSVLASVANTVLDSISPGEADEVRRQLPK
MMAR_3726|M.marinum_M -------------------------
MUL_3669|M.ulcerans_Agy99 -------------------------
MAV_1776|M.avium_104 -------------------------
Mvan_3907|M.vanbaalenii_PYR-1 -------------------------
MAB_2708|M.abscessus_ATCC_1997 GIAREIAGIRRKLVYLSSTSSFR--
MSMEG_2183|M.smegmatis_MC2_155 SIGRDVSGLQRKLDYLASTSTFSPW
Mflv_3086|M.gilvum_PYR-GCK DGLREIAAVRRRVGSAGLTGI----
TH_4428|M.thermoresistible__bu ELQDVLAAPAAGS------------