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TSSMSQTAAAPNHLRRLKEFTLSRQGRPALVGALGAVLLTAGGLGAGSTRLHDPLLESMHLSWLRFGHGL VVSSLLLWGGVALMVLAWVWLGRHVIDRTATQYTMLATTAFWLTPLLLSVPLFSRDTYSYLAQGALLRDG FDPYVVGPIENPNSLLDNVSPIWTTTTAPYGPAFILVAKFVTMLVGDDVVAGTMLLRLCMLPGLALLIWA APRVARHVGASGAAALWIAVLNPLVIIHLMGGVHNEMLMVGLMMAGIALCFAGRNVSGVTLIAVAVAVKA TAGLALPFMVWVWARQLRDRRGFSPAKAFAAATVGSVLVFVVVFAVLSLAAGVGLGWLTALAGSVKIINW LTVPTAIANLTNAVVGLVMPVNFYAVLETTRIIGIGVIAISAPVLWWRYRRTDRDALMGIALVMAVVVLF VPAALPWYYTWPLAVIAALAQSRRSIALIAGFSTWITAIWRPDGAHGMYSWAHVLLATACAAAAWYWLSK QPEGADRPEDFSTPSPARDEPPRGPDASAARRPDAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2974 | - | - | 100% (527) | hypothetical protein Mflv_2974 |
| M. gilvum PYR-GCK | Mflv_3679 | - | 1e-61 | 30.81% (529) | hypothetical protein Mflv_3679 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2196 | - | 0.0 | 70.72% (485) | integral membrane protein |
| M. tuberculosis H37Rv | Rv2174 | - | 0.0 | 70.52% (485) | integral membrane protein |
| M. leprae Br4923 | MLBr_00899 | - | 0.0 | 69.85% (481) | putative integral-membrane protein |
| M. abscessus ATCC 19977 | MAB_1991c | - | 0.0 | 65.02% (486) | hypothetical protein MAB_1991c |
| M. marinum M | MMAR_3209 | - | 0.0 | 68.42% (494) | hypothetical protein MMAR_3209 |
| M. avium 104 | MAV_2319 | - | 0.0 | 69.68% (498) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_4241 | - | 0.0 | 80.17% (484) | integral membrane protein |
| M. thermoresistible (build 8) | TH_0709 | - | 0.0 | 73.62% (527) | Possible conserved integral membrane protein |
| M. ulcerans Agy99 | MUL_3517 | - | 0.0 | 68.79% (471) | hypothetical protein MUL_3517 |
| M. vanbaalenii PYR-1 | Mvan_3537 | - | 0.0 | 84.50% (516) | hypothetical protein Mvan_3537 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2974|M.gilvum_PYR-GCK ---------MTSSMSQTAAAP---NHLRRLKEFTLSRQGRPALVGALGAV
Mvan_3537|M.vanbaalenii_PYR-1 ---------MTTPAPPQAPRTDLSDHLRRLREFTLSPQARPALVGALGAT
MSMEG_4241|M.smegmatis_MC2_155 ----------MTPTETHKPNPGLAEHVSRLAAFAVSAEARPARLGCLGAT
TH_0709|M.thermoresistible__bu --------MTASTSSTDLPKSGLGGQISRLNQFARSAAGRPALLGGLGAV
Mb2196|M.bovis_AF2122/97 ----MTTPSHAPAVDLATAKDAVVQHLSRLFEFTTGPQGGPARLGFAGAV
Rv2174|M.tuberculosis_H37Rv ----MTTPSHAPAVDLATAKDAVVQHLSRLFEFTTGPQGGPARLGFAGAV
MMAR_3209|M.marinum_M ----MTSPTPTPEA-LSVTKMSVRQRLSRIREFASSPQAGPARLGLLGAV
MUL_3517|M.ulcerans_Agy99 -------------------------------------------------M
MAV_2319|M.avium_104 ----MATGTDTPAADPPAAKPSRGQWFSRLKAFAGSADSGPAKLGMLGSV
MLBr_00899|M.leprae_Br4923 ----MTTPTHLPEANSPTKR-YIHQYFSQLRMFAASPESGPAKLGLLGSL
MAB_1991c|M.abscessus_ATCC_199 MSTSSKALEPSQEPKPDPDSPAPAPAPGWVSSFLRSPAGRAATIGFGGAI
Mflv_2974|M.gilvum_PYR-GCK LLTAGGLGAGSTRLHDPLLESMHLSWLRFGHGLVVSSLLLWGGVALMVLA
Mvan_3537|M.vanbaalenii_PYR-1 LITAGGLGAGSTRLHDPVLESMHLSWLRFGHGLVVSSLLLWGGVALMLMA
MSMEG_4241|M.smegmatis_MC2_155 VLTIGGLGAGSTRLHDPLLESLHLSWLRFGHGLVVSSILLWTGVALMLIA
TH_0709|M.thermoresistible__bu LITAGGLGAGSTRVHDPLLESLYLSWLRFGHGLVVSSTLLWTGVTLMLIA
Mb2196|M.bovis_AF2122/97 LITAGGLGAGSVRQHDPLLESIHMSWLRFGHGLVLSSILLWTGVGVMLLA
Rv2174|M.tuberculosis_H37Rv LITAGGLGAGSVRQHDPLLESIHMSWLRFGHGLVLSSILLWTGVGVMLLA
MMAR_3209|M.marinum_M LITVGGLGAGSIRQHDPLLESIHMSWLRFGHGLVLSSIVLWLGVGLMLIA
MUL_3517|M.ulcerans_Agy99 LITVGGLGAGSIRQHDPLLESIHMSWLRFGHGLVLSSIVLWLGVGLMLIA
MAV_2319|M.avium_104 LITLGGLGAGSTRQHDPLLESIHMSWLRFGHGLVLSSIVLWTGVGLMLIA
MLBr_00899|M.leprae_Br4923 LITTGGLGAGSIRQHDPLLELICMSWLRFGHGLVLSSILLWTGVSLMLIA
MAB_1991c|M.abscessus_ATCC_199 LVAIGGLGAGSTRQHDPLLESAGLSWLRFGHGLVVSSICMWLGVVLMLLA
::: ******* * ***:** :**********:** :* ** :*::*
Mflv_2974|M.gilvum_PYR-GCK WVWLGRHVIDRTATQYTMLATTAFWLTPLLLSVPLFSRDTYSYLAQGALL
Mvan_3537|M.vanbaalenii_PYR-1 WLWLGRRVVDRTATEYTMIATTGFWLAPLLLSVPVFSRDTYSYLAQGALL
MSMEG_4241|M.smegmatis_MC2_155 WLWLGRRVIDRTATEYTMVATTGFWLAPLLLSVPLFSRDTYSYLAQGALL
TH_0709|M.thermoresistible__bu WLWLGRHVITGRATEYGMIATTGFWLVPLLLSVPVFSRDTYSYLAQGALL
Mb2196|M.bovis_AF2122/97 WLGLGRRVLAGEATEFTMRATTVIWLAPLLLSVPVFSRDTYSYLAQGALL
Rv2174|M.tuberculosis_H37Rv WLGLGRRVLAGEATEFTMRATTVIWLAPLLLSVPVFSRDTYSYLAQGALL
MMAR_3209|M.marinum_M WLRLGRGVLAGQASEFTMRATTAFWLAPLLLSVPIFSRDTYSYLAQGALL
MUL_3517|M.ulcerans_Agy99 WLRLGRGVLAGQASEFTMRATTAFWLAPLLLSVPIFSRDTYSYLAQGALL
MAV_2319|M.avium_104 WLSLGRRVLAGEATEFVMKATTGFWLAPLLVSVPVFSRDTYSYLAQGALL
MLBr_00899|M.leprae_Br4923 WLRLGRRVLAGQATEFMMRATIGFWLTPLLLSVPVFSRDTYSYLAQGALL
MAB_1991c|M.abscessus_ATCC_199 WLGLGRHVIAGKVTKESLLIVIPCWLLPLLASVPVFSRDAYSYLAQGALL
*: *** *: .:: : . ** *** ***:****:**********
Mflv_2974|M.gilvum_PYR-GCK RDGFDPYVVGPIENPNSLLDNVSPIWTTTTAPYGPAFILVAKFVTMLVGD
Mvan_3537|M.vanbaalenii_PYR-1 RDGFDPYVVGPVENPNSLLDDVSPIWTTTTAPYGPAFILVAKFVTILVGN
MSMEG_4241|M.smegmatis_MC2_155 RDGFDPYVVGPVENPNSLLENVSPIWTTTTAPYGPAFILVAKFVTMLVGN
TH_0709|M.thermoresistible__bu RDGFDPYLVGPVENPNPLLDDVSPIWTTTTAPYGPAFILVAKFVTMLVND
Mb2196|M.bovis_AF2122/97 RDGLDPYAVGPVGNPNALLDDVSPIWTITTAPYGPAFILVAKFVTVIVGN
Rv2174|M.tuberculosis_H37Rv RDGLDPYAVGPVGNPNALLDDVSPIWTITTAPYGPAFILVAKFVTVIVGN
MMAR_3209|M.marinum_M RDGLDPYAVGPVANANSLLNDVSPIWTITTAPYGPAFILVAKVVTMIVGN
MUL_3517|M.ulcerans_Agy99 RDGLDPYAVSPVANANSLLNDVSPIWTITTAPYGPAFILVAKVVTMIVGN
MAV_2319|M.avium_104 RDGLDPYAVGPVANPNSLLDNVSPIWSITTAPYGPVFILVAKIITILVGN
MLBr_00899|M.leprae_Br4923 RDGLDPYLVGPVGNPNALLDNVSPIWTITTAPYGPAFILVAKFVTLAVGN
MAB_1991c|M.abscessus_ATCC_199 RDGFDPYLVGPVENPNALLENVSPIWTTTTAPYGPLFLLIARFVTQIVGD
***:*** *.*: *.*.**::*****: ******* *:*:*:.:* *.:
Mflv_2974|M.gilvum_PYR-GCK DVVAGTMLLRLCMLPGLALLIWAAPRVARHVGASGAAALWIAVLNPLVII
Mvan_3537|M.vanbaalenii_PYR-1 DVVAGTMLLRLCMLPGLALLIWAVPRVARHVGASGVAALWIGVLNPLMIV
MSMEG_4241|M.smegmatis_MC2_155 DVVAGTMLLRLCMLPGLLLLIWAAPRVARHVGANAAAALWICVLNPLVII
TH_0709|M.thermoresistible__bu NVVAGTMLLRLCMLPGLALLIWAAPRVARHIGANPAAALWICVLNPLVII
Mb2196|M.bovis_AF2122/97 NVVAGTMLLRLCMLPGLALLVWATPRLASHLGTHGPTALWICVLNPLVLI
Rv2174|M.tuberculosis_H37Rv NVVAGTMLLRLCMLPGLALLVWATPRLASHLGTHGPTALWICVLNPLVLI
MMAR_3209|M.marinum_M NVVAGTMLLRLCMLPGLALLIWATPRLAHHLGADSPTAMWICVLNPLVLI
MUL_3517|M.ulcerans_Agy99 NVVAGTMLLRLCMLPGLALLIWATPRLAHHLGADSPTAMWICVLNPLVLI
MAV_2319|M.avium_104 NVVAGTALLRLCMLPGLVLLIWATPRLARHLGADEPTALWICVLNPLVLI
MLBr_00899|M.leprae_Br4923 NVVTGTMLLRLCMLPGLALLIWATPRLAQHFGADGTTALWTCVLNPLVLI
MAB_1991c|M.abscessus_ATCC_199 DVVAGTMLLRLCMLPGLALLVWATPRVAQFFSASASKALWICVLNPLVII
:**:** ********** **:**.**:* ...: *:* *****:::
Mflv_2974|M.gilvum_PYR-GCK HLMGGVHNEMLMVGLMMAGIALCFAGRNVSGVTLIAVAVAVKATAGLALP
Mvan_3537|M.vanbaalenii_PYR-1 HLMGGVHNEMLMVGLMMAGIALCLSGRNVWGITLIAVAVAVKATAGLALP
MSMEG_4241|M.smegmatis_MC2_155 HLMGGVHNEMLMVGLMMAAIALTFAGRPIWGVGLIATAVAVKATAGLALP
TH_0709|M.thermoresistible__bu HLMGGVHNEMLMVGLMMAGIALTLSRHPVWGVASIAVAVAVKATAGLALP
Mb2196|M.bovis_AF2122/97 HLMGGVHNEMLMVGLMTAGIALTVQGRNVAGIILITVAIAVKATAGIALP
Rv2174|M.tuberculosis_H37Rv HLMGGVHNEMLMVGLMTAGIALTVQGRNVAGIILITVAIAVKATAGIALP
MMAR_3209|M.marinum_M HLMGGVHNEMLMVGLMAAGIALTLQRHHVAGIALITVAVAVKATAGLALP
MUL_3517|M.ulcerans_Agy99 HLMGGVHNEMLMVGLMAAGIALTLQRHHVAGIALITVAVAVKATAGLALP
MAV_2319|M.avium_104 HLMGGVHNEMLMVGLMAAGIALTFGGRPVAGVTLITVAIAVKATAGIALP
MLBr_00899|M.leprae_Br4923 HLMGGVHNEMLMVGLMTAGVALTFQGRNVAGTALITVAIAVKATAGISLP
MAB_1991c|M.abscessus_ATCC_199 HLMGGVHNEMLMVGLMMAGIALTLERHHVWGIAVVALGVMVKASAGLALP
**************** *.:** . : : * :: .: ***:**::**
Mflv_2974|M.gilvum_PYR-GCK FMVWVWARQLRDRRG-----FSPAKAFAAATVGSVLVFVVVFAVLSLAAG
Mvan_3537|M.vanbaalenii_PYR-1 FMVWVWARRLRDRRG-----LAPVKAFAAATAASLVIFVAVFSVLSLAAG
MSMEG_4241|M.smegmatis_MC2_155 FMVWVWMRQLRDRHD-----MPPVRAFVVSTAASVLIFGAVFAVLSWVAG
TH_0709|M.thermoresistible__bu FMVWVWMRQLREQRS-----LSPAAAFAIATAASLAIFAAVFAVLSWVAG
Mb2196|M.bovis_AF2122/97 FLVWVWLRHLRERRG-----YRPVQAFLAAAAISLLIFVAVFAVLSAVAG
Rv2174|M.tuberculosis_H37Rv FLVWVWLRHLRERRG-----YRPVQAFLAAAAISLLIFVAVFAVLSAVAG
MMAR_3209|M.marinum_M FLFWVWMRHLHERRG-----YRPAHAFLVAAAASLLVFLAVFSVLSAVAR
MUL_3517|M.ulcerans_Agy99 FLFWVWMRHLHERRG-----YRPAHAFLVAAAASLLVFLAVFSVLSAVAR
MAV_2319|M.avium_104 FLVWVWARQLRDQRG-----YRPVPAFFAATAASLLIFAVVFAALSAVAG
MLBr_00899|M.leprae_Br4923 FMVWVWMRQLHNRRG-----YRPVQAFLAATATALLIFATVFAVLSTAAS
MAB_1991c|M.abscessus_ATCC_199 FLVWIWMRRLASDHVDGAPPRRPPAAFALASIGSVAISLTTFALMSWITG
*:.*:* *:* . : * ** :: :: : ..*: :* :
Mflv_2974|M.gilvum_PYR-GCK VGLGWLTALAG-SVKIINWLTVPTAIANLTNAVVGLVMPVNFYAVLETTR
Mvan_3537|M.vanbaalenii_PYR-1 VGLGWLNALAAGNVKIINWLTVPTALANLINAVGGLVFPVNFYAVIDVTR
MSMEG_4241|M.smegmatis_MC2_155 VGLGWLTALAG-SVKIINWLTVPTAASNLINAIGGLFFSVNFYAVLEVAR
TH_0709|M.thermoresistible__bu VGLGWLTALAG-SVKIINWLTVPTAVANLTNAIGGMFLPVNFYAVLEVTR
Mb2196|M.bovis_AF2122/97 VGLGWLTALAG-SVKIINWLTVPTGAANVIHALGRGLFTVDFYTLLRITR
Rv2174|M.tuberculosis_H37Rv VGLGWLTALAG-SVKIINWLTVPTGAANVIHALGRGLFTVDFYTLLRITR
MMAR_3209|M.marinum_M VGLGWLTALAG-SVKIINWLTLPTGAANLIHALGRNFFTLDFYTLLHVTR
MUL_3517|M.ulcerans_Agy99 VGLGWLTALAG-SVKIINWLTLPTGAANLIHALGRNFFTLDFYTLLHVTR
MAV_2319|M.avium_104 VGLGWLTALAG-SVKIINWLTVPTAAANLIHAIGSGFFPVSFYPILRVTR
MLBr_00899|M.leprae_Br4923 VGLGWMTALAG-SVKIINWLTVPTAIANLVNVLANGFFATDFYGVLRMTR
MAB_1991c|M.abscessus_ATCC_199 VGFGWLTAFAGSAVKIINWLTIPTAVANVINVVAGLFVTVNFDAVLEVMR
**:**:.*:*. ********:**. :*: :.: ... .* :: *
Mflv_2974|M.gilvum_PYR-GCK IIGIGVIAISAPVLWWRYRRTDRDALMGIALVMAVVVLFVPAALPWYYTW
Mvan_3537|M.vanbaalenii_PYR-1 IVGLAIIAISAPVLWWRLRHTDREALMGIALVMAVVVLFVPAALPWYYTW
MSMEG_4241|M.smegmatis_MC2_155 IIGIAAIVIALPLLWWRYRHTDREALTGIALAMVVVVLFVPAALPWYYTW
TH_0709|M.thermoresistible__bu IIGIAIIVVTLPVVWWRFRHDDRGALTGIAVAMLVVVLFVPAALPWYYTW
Mb2196|M.bovis_AF2122/97 LIGIVIIAVSLPLLWWRFRRDDRAALTGVAWSMLIVVLFVPAALPWYYSW
Rv2174|M.tuberculosis_H37Rv LIGIVIIAVSLPLLWWRFRRDDRAALTGVAWSMLIVVLFVPAALPWYYSW
MMAR_3209|M.marinum_M LIGIAIIAVSLPLLWWRFRRDDRAALTGIAWSMLIVVLFVPAALPWYYSW
MUL_3517|M.ulcerans_Agy99 LIGIAIIAVSLPLLWWRFRRDDRAALTGIAWSMLIVVLFVPAALPWYYSW
MAV_2319|M.avium_104 LVGIAIIAISLPLLWWRFRRDDRDALTGIAISMLIVVLFVPAALPWYYSW
MLBr_00899|M.leprae_Br4923 FIGIVIIAVSLPLLWWRYRRDDRSALTGIAWSMLIVVLFVPAALPWYYSW
MAB_1991c|M.abscessus_ATCC_199 IIGVLVIAVSLPVVWWRHRHNERDAMFGILWAMSIVVLMAPAALPWYYSW
::*: *.:: *::*** *: :* *: *: * :***:.********:*
Mflv_2974|M.gilvum_PYR-GCK PLAVIAALAQSRRSIALIAGFSTWITAIWRPDGAHGMYSWAHVLLATACA
Mvan_3537|M.vanbaalenii_PYR-1 PLAVVAALATSRRSMALIAGFSTWITVIWRPDGAHGMYSWGHVLLSLSCA
MSMEG_4241|M.smegmatis_MC2_155 PLAVAAALVQTRPGIAAIAGFSTWIMVMWKPDGAHGMYSWAHVLLTTACA
TH_0709|M.thermoresistible__bu PLAVLSALAQSRPAIALIAGFSTWIMVIFRPDGAHGMYSWTHVLIATGCA
Mb2196|M.bovis_AF2122/97 PLAVAAPLAQSRRAIAAIAGLSTWVMVIFKPDGSHGMYSWLHFWIATACA
Rv2174|M.tuberculosis_H37Rv PLAVAAPLAQARRAIAAIAGLSTWVMVIFKPDGSHGMYSWLHFWIATACA
MMAR_3209|M.marinum_M PLAVAAPLAQSRRSMAAIAGISTWIMVIFKPDGSHGMYSWLHFWIATSCA
MUL_3517|M.ulcerans_Agy99 PLAVAAPLAQSRRSMAAVAGISTWIMVIFKPDGSHGMYSWLHFWIATGCA
MAV_2319|M.avium_104 PLAVLAPLAQSRRAVAIIGGLSTWVMVIFKPDGSHGMYSWLHFSLATAVA
MLBr_00899|M.leprae_Br4923 PLAVAAPLAQSRQALATIAGFSSWIMVIFKPDGSHGMYSWLHFSLATTCA
MAB_1991c|M.abscessus_ATCC_199 PLAIAAPLLQSRGAIAAIAGFSTWIMVIFKPDGSHGMYVWIHVLIAATCA
***: :.* :* .:* :.*:*:*: .:::***:**** * *. :: *
Mflv_2974|M.gilvum_PYR-GCK AAAWYWLSKQPEGADRPEDFSTPSPARDEPPRGPDASAARRPDAR-----
Mvan_3537|M.vanbaalenii_PYR-1 AAAWYWLYKAPEGT--AEAVSTPSPARDEPPHEPDASATHRPGGR-----
MSMEG_4241|M.smegmatis_MC2_155 VAAWYSLYRAPESA--------------------EATASRQ---------
TH_0709|M.thermoresistible__bu VAAWWWLYRTESTP---------------AEPIPQSGGSAGESGR-----
Mb2196|M.bovis_AF2122/97 LTAWYVLYRSPDRR--------------GVQAATPVVNTP----------
Rv2174|M.tuberculosis_H37Rv LTAWYVLYRSPDRR--------------GVQAATPVVNTP----------
MMAR_3209|M.marinum_M LAAWYALYRAPDLR--------------TRPGETPADEPAAPLDMGTKDP
MUL_3517|M.ulcerans_Agy99 LAAWYALYRAPDLR--------------TRPGETPADEPAAPLDMGTKDP
MAV_2319|M.avium_104 LVAWYSLYRVP----------------------QPAQ-------------
MLBr_00899|M.leprae_Br4923 LIAWHALYKAP---------------------ETDTA-------------
MAB_1991c|M.abscessus_ATCC_199 AIAWRMINTAPE---------------------PDGSAPAA---------
** :
Mflv_2974|M.gilvum_PYR-GCK -
Mvan_3537|M.vanbaalenii_PYR-1 -
MSMEG_4241|M.smegmatis_MC2_155 -
TH_0709|M.thermoresistible__bu -
Mb2196|M.bovis_AF2122/97 -
Rv2174|M.tuberculosis_H37Rv -
MMAR_3209|M.marinum_M Q
MUL_3517|M.ulcerans_Agy99 H
MAV_2319|M.avium_104 -
MLBr_00899|M.leprae_Br4923 -
MAB_1991c|M.abscessus_ATCC_199 -