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SAERLIDTHCHVSAYTDPVAMLREADEAGVAVVAVTEDPEEYRRLRTRLGRREHVEVALGLHPLRAASFG PNELARFFRLVPQANWIGEVGLDYSRAGADTAKAQQRVFDVVLTEAQPGRHPLTVHSRGAEKDVVRRLAD AGLPAILHWYTGPVNLAEEALQAGLYFSVNIAMVRSRKFPSLMRAIPRDRILLETDGPYAKDRGRPAQPG RLNELATALGTSWGTDRVETTNILRANQTRFLNRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2878 | - | - | 100% (246) | TatD-related deoxyribonuclease |
| M. gilvum PYR-GCK | Mflv_1931 | - | 1e-12 | 28.12% (256) | TatD family hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1035 | tatD | 1e-14 | 31.28% (211) | deoxyribonuclease TatD (YjjV protein) |
| M. tuberculosis H37Rv | Rv1008 | tatD | 2e-14 | 31.28% (211) | deoxyribonuclease TatD (YjjV protein) |
| M. leprae Br4923 | MLBr_00239 | - | 1e-13 | 29.38% (211) | hypothetical protein MLBr_00239 |
| M. abscessus ATCC 19977 | MAB_1129 | - | 2e-15 | 28.87% (239) | deoxyribonuclease TatD |
| M. marinum M | MMAR_4480 | tatD | 1e-12 | 27.03% (259) | deoxyribonuclease TatD |
| M. avium 104 | MAV_1146 | - | 2e-12 | 29.77% (215) | hydrolase, TatD family protein |
| M. smegmatis MC2 155 | MSMEG_5440 | - | 6e-13 | 27.54% (236) | deoxyribonuclease |
| M. thermoresistible (build 8) | TH_0978 | - | 8e-08 | 30.67% (150) | PROBABLE DEOXYRIBONUCLEASE TATD (YJJV PROTEIN) |
| M. ulcerans Agy99 | MUL_3214 | - | 6e-19 | 33.33% (225) | TatD family deoxyribonuclease |
| M. vanbaalenii PYR-1 | Mvan_4802 | - | 1e-13 | 29.46% (224) | TatD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1035|M.bovis_AF2122/97 --------------------------MVDAHTHLDACGAR---DADTVRS
Rv1008|M.tuberculosis_H37Rv --------------------------MVDAHTHLDACGAR---DADTVRS
MMAR_4480|M.marinum_M ----MRVSSNRAAEREAPPAPQPLAPLIDAHTHLDACGAA---DAAGVIA
MLBr_00239|M.leprae_Br4923 --------------------------MVDAHTHLDACGAR---DADDVNA
MAV_1146|M.avium_104 ----MRVSSNRR-ERQAPPAPEPLAPLIDAHTHLDACAAGPETGAADVRA
MSMEG_5440|M.smegmatis_MC2_155 -------MSAKRSAREKPPAPEPLTPLVDAHTHLDACGAD---NPEDVRA
TH_0978|M.thermoresistible__bu --------------------------------------------------
Mvan_4802|M.vanbaalenii_PYR-1 -------MSATKQRREPPPIPQPLAPLIDAHTHLDACGAR---NADDVRA
MAB_1129|M.abscessus_ATCC_1997 MTPGNNRQAPPDRIRSRPPDPEPLAPLIDAHTHLDACGAV---TAADVRA
Mflv_2878|M.gilvum_PYR-GCK ---------------------MSAERLIDTHCHVSAYTDP--------VA
MUL_3214|M.ulcerans_Agy99 ----------------------MGLPSLDCHAHVSPSVTD----------
Mb1035|M.bovis_AF2122/97 LVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADAL
Rv1008|M.tuberculosis_H37Rv LVERAAAAGVTAVVTVADDLESARWVTRAAEWDRRVYAAVALHPTRADAL
MMAR_4480|M.marinum_M IVDRAAAVGVEAVVTIADDLESARWVTRAAEWDPRVYAAVALHPTRTDAL
MLBr_00239|M.leprae_Br4923 IVERAAAVGVVAVVTVADDLESARWVIAAAGWDRRVYAAVALHPTRANSL
MAV_1146|M.avium_104 IVDRAAAVGVQAVVTVADDLDSARWVTRAAEWDPRVYAATALHPTRADAL
MSMEG_5440|M.smegmatis_MC2_155 IVDRAAAVGVGRVVTIADDLDAAHWVTRAADADDRVWAAVALHPTRADTL
TH_0978|M.thermoresistible__bu --------------------------------------------------
Mvan_4802|M.vanbaalenii_PYR-1 ILDRAASAGVQAVVTIADDLEAARWAAEAADWDPRVYAAVALHPTRANAL
MAB_1129|M.abscessus_ATCC_1997 MVDHAESVGVGRVVTVADDLDSARWAVSAAAADPRVYAAVALHPTRAGNL
Mflv_2878|M.gilvum_PYR-GCK MLREADEAGVAVVAVTEDPEEYRRLRTRLGRRE-HVEVALGLHPLRAASF
MUL_3214|M.ulcerans_Agy99 --RQIAQLGTAIVFAMTR--EPAEAVEAAQRRDHNILWGCGAHPSYVARG
Mb1035|M.bovis_AF2122/97 TDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHI
Rv1008|M.tuberculosis_H37Rv TDAARAELERLVAHPRVVAVGETGIDMYWPGRLDGCAEPHVQREAFAWHI
MMAR_4480|M.marinum_M TEAARREIEELVAHRRVVAVGETGMDMYWPGRLEGCADPDVQREAFAWHI
MLBr_00239|M.leprae_Br4923 TSAARAKIEQLAAHPRMVAVGETGMDLYWPGRLDSCAPPDVQREAFAWHI
MAV_1146|M.avium_104 DDAARAEIERLVAHPRVVAVGETGMDLYWPGRLDGCAEPAVQREAFAWHI
MSMEG_5440|M.smegmatis_MC2_155 TDAAKADLEQLATHPRVVAIGETGMDLYWPGRLDGCATPAEQRDAFAWHI
TH_0978|M.thermoresistible__bu ----------------VVAIGETGMDLYWPGRLDGCADPAAQREAFAWHI
Mvan_4802|M.vanbaalenii_PYR-1 TPEARSVIERLAAHPRVVAVGETGMDLYWPGRLEGCAEPADQREAFAWHI
MAB_1129|M.abscessus_ATCC_1997 TDEARAELETLAAHPRVVAIGETGLDLYWPGRLEGCAEPSIQREAFAWHI
Mflv_2878|M.gilvum_PYR-GCK GPNELARFFRLVP--QANWIGEVGLDYSRAG----ADTAKAQQRVFDVVL
MUL_3214|M.ulcerans_Agy99 GAVDLDEFARCATG--FAIVGEIGMDR-------RSGNLHHQAEVFDALL
:** *:* . * .* :
Mb1035|M.bovis_AF2122/97 DLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCV
Rv1008|M.tuberculosis_H37Rv DLAKRTGKPLMIHNRQADRDVLDVLRAEGAPDTVILHCFSSDAAMARTCV
MMAR_4480|M.marinum_M DLAKRTGKPLMIHNRQADREVLDVLRAEGAPDTVIFHCFSSDAAMARECV
MLBr_00239|M.leprae_Br4923 DLAKRCGKPLMIHNRQADAEVLDVLRAEGAPEQVIFHCFSSNAAMARRCV
MAV_1146|M.avium_104 DLAKRCGKPLMIHNREADAEVLDVLAAEGAPDVVIFHCFSSDAAMARRCV
MSMEG_5440|M.smegmatis_MC2_155 DLAKRSGKPLMIHNREADAEVLDVLRAEGAPETVIFHCFSSGPAMARTCI
TH_0978|M.thermoresistible__bu DLAKRTGKPLMIHNREADAEVLDVLRAEGAPETVIMHCFSSDAVMARTCV
Mvan_4802|M.vanbaalenii_PYR-1 DLAKRTGKPLMIHNRDADAAVLDVLRAEGAPETVIFHCFSSGAAMARACI
MAB_1129|M.abscessus_ATCC_1997 ELAKRTGKPLMIHNRDADADVLDVLKAEGAPGSVIFHCFSSDADMAKKCI
Mflv_2878|M.gilvum_PYR-GCK TEAQPGRHPLTVHSRGAEKDVVRRLADAGLP--AILHWYTGPVNLAEEAL
MUL_3214|M.ulcerans_Agy99 DRLKDEPVLLSVHSAGCTAEVAKIVRLRRTQG-VIMHWFSGRPEEVDELL
: * :*. . * : .*:* ::. . :
Mb1035|M.bovis_AF2122/97 DAGWLLSLSGTVSFRNARELREAVPLMPVEQLLVETDAPYLTPHPHRGLA
Rv1008|M.tuberculosis_H37Rv DAGWLLSLSGTVSFRTARELREAVPLMPVEQLLVETDAPYLTPHPHRGLA
MMAR_4480|M.marinum_M AAGWLLSLSGTVSFRNARELREAVPLIPLDQLLVETDAPFLTPHPYRGAA
MLBr_00239|M.leprae_Br4923 DAGWMLSLSGTVSFRNARPLREAVPLIPAQQLLVETDAPFLTPHPHRGLA
MAV_1146|M.avium_104 DAGWLLSLSGTVSFRNARALREAVPLIPPGQLLVETDAPFLTPHPHRGTA
MSMEG_5440|M.smegmatis_MC2_155 DAGWVLSLSGTVSFKNARDLQEAARLIPQGQMLVETDAPFLTPHPFRGAP
TH_0978|M.thermoresistible__bu EAGWVLSLSGTVSFRNARALHEAAPLIPPGQMLVETDAPYLTPHPYRGAP
Mvan_4802|M.vanbaalenii_PYR-1 DEGWLLSLSGTVSFKNARDLREAVPLIPADQMLVETDAPFLTPHPFRGAP
MAB_1129|M.abscessus_ATCC_1997 AEGWILSLSGTVSFKNARALQEAAALIPDEQLLVETDAPYLTPHPHRGAP
Mflv_2878|M.gilvum_PYR-GCK QAGLYFSVN--IAMVRSRKFPSLMRAIPRDRILLETDGPYAK---DRGRP
MUL_3214|M.ulcerans_Agy99 SLGCYFSVNTAMR-------REILTALPLDRLLPETDFPVAR----RRTG
* :*:. : . :* ::* *** * *
Mb1035|M.bovis_AF2122/97 NEPYCLPYTVRALAELVNRRPEEVALITTSNARRAYGLGWMRQ-------
Rv1008|M.tuberculosis_H37Rv NEPYCLPYTVRALAELVNRRPEEVALITTSNARRAYGLGWMRQ-------
MMAR_4480|M.marinum_M NEPYCLPYTVRALAELLNGSAEELAQVTASNARRVYGLG-----------
MLBr_00239|M.leprae_Br4923 NEPYCLPYTVRAVAELVERSPEELAQITTSNALRVYKLGSV---------
MAV_1146|M.avium_104 NEPYCLPYTVRAIAELVDRRPEELAAVTTDNARRVYGLA-----------
MSMEG_5440|M.smegmatis_MC2_155 NEPYCLPYTVRALATLLDRPAEEIAAETAATAERVYRLSESCRF------
TH_0978|M.thermoresistible__bu NEPYCLPYTVRALADLLGRPAEDVAWETADTAVSVYGLDESCRI------
Mvan_4802|M.vanbaalenii_PYR-1 NEPYCLPYTVRALAEVLSRPAETIAEQTSATAKRVYGLASCWN-------
MAB_1129|M.abscessus_ATCC_1997 NEPYCLPYTVRALAEITGRTADRLAEASSTTAIAVFKIVDELPPRDAFVT
Mflv_2878|M.gilvum_PYR-GCK AQPGRLNELATALGTSWGTDRVETTNILRANQTRFLNRA-----------
MUL_3214|M.ulcerans_Agy99 SKPGDTDQLEKLLAEIHDSDPMHVRRQFYRNLRRMSVGTGAIDRMPMHVA
:* :. .
Mb1035|M.bovis_AF2122/97 ------
Rv1008|M.tuberculosis_H37Rv ------
MMAR_4480|M.marinum_M ------
MLBr_00239|M.leprae_Br4923 ------
MAV_1146|M.avium_104 ------
MSMEG_5440|M.smegmatis_MC2_155 ------
TH_0978|M.thermoresistible__bu ------
Mvan_4802|M.vanbaalenii_PYR-1 ------
MAB_1129|M.abscessus_ATCC_1997 VS----
Mflv_2878|M.gilvum_PYR-GCK ------
MUL_3214|M.ulcerans_Agy99 DLLLAA