For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RSRLRWTVFALVVIAAMAVAIWPRTPQVDGTNTSGPGLTLPAAAVGDADTGELARLTARAALAPCPTPRE GAPPKGDLAGALASCLGARTMFDVGAALAGEQTLINLWASWCAPCREEIPVLDAYAGQPGAVRVVGMNVQ DTDTVALSLLADLGVHYPSFGNADAVGQVLGAPPVLPLSYLVGTDGTVRRVTTPTVFRDVEQVRAAVAAM NP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2864 | - | - | 100% (213) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen |
| M. gilvum PYR-GCK | Mflv_1374 | - | 3e-28 | 35.96% (203) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
| M. gilvum PYR-GCK | Mflv_2869 | - | 3e-09 | 31.76% (148) | alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3697c | - | 1e-25 | 37.32% (209) | membrane-anchored thioredoxin-like protein |
| M. tuberculosis H37Rv | Rv3673c | - | 1e-25 | 37.32% (209) | membrane-anchored thioredoxin-like protein |
| M. leprae Br4923 | MLBr_02300 | - | 1e-19 | 36.59% (164) | hypothetical protein MLBr_02300 |
| M. abscessus ATCC 19977 | MAB_0419 | - | 1e-20 | 31.73% (208) | hypothetical protein MAB_0419 |
| M. marinum M | MMAR_5161 | - | 3e-24 | 34.95% (206) | membrane-anchored thioredoxin-like protein |
| M. avium 104 | MAV_0456 | - | 3e-24 | 34.12% (211) | hypothetical protein MAV_0456 |
| M. smegmatis MC2 155 | MSMEG_6186 | - | 2e-29 | 38.46% (208) | hypothetical protein MSMEG_6186 |
| M. thermoresistible (build 8) | TH_2251 | - | 5e-06 | 37.88% (66) | POSSIBLE THIOREDOXIN PROTEIN (THIOL-DISULFIDE INTERCHANGE |
| M. ulcerans Agy99 | MUL_4247 | - | 5e-22 | 34.98% (203) | membrane-anchored thioredoxin-like protein |
| M. vanbaalenii PYR-1 | Mvan_5432 | - | 2e-27 | 34.83% (201) | redoxin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3697c|M.bovis_AF2122/97 MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTI
Rv3673c|M.tuberculosis_H37Rv MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTI
MLBr_02300|M.leprae_Br4923 ------------MKTLTPKTCGTIVVLAVVVALVAALVGQLRDNARTIEM
MMAR_5161|M.marinum_M ---------MPELTRLTPGARWTIAVLAVVVALIIALAAQLREGSGPAGH
MUL_4247|M.ulcerans_Agy99 -------------------------MLAVVVALIIALAAQLREGSGSAGH
MAV_0456|M.avium_104 --------MPIPRPTLTRKVRWHIAILAVVVALIVALLAQLRDDAATPGP
MSMEG_6186|M.smegmatis_MC2_155 ---------------MSVSTRWTVAVLVVLLALGTAFWLELRDDGAAPGA
Mvan_5432|M.vanbaalenii_PYR-1 ------------------------MALVIVVALGAALWAELDADESQPRT
MAB_0419|M.abscessus_ATCC_1997 ------------MARLNTGARWTIAGVVLVAALIAVMLSQQHDQQRRGPQ
Mflv_2864|M.gilvum_PYR-GCK ---------------MRSRLRWTVFALVVIAAMAVAIWPRTPQVDGTNTS
TH_2251|M.thermoresistible__bu ------------------------VKRLVVLLVGTAMLVLTGCSTGDDAV
:: : .:
Mb3697c|M.bovis_AF2122/97 SQR---PAPREHRDGDTPEALAWSRQRANLPPCP-AAGNGPGAAALRGVV
Rv3673c|M.tuberculosis_H37Rv SQR---PAPREHRDGDTPEALAWSRQRANLPPCP-AAGNGPGAAALRGVV
MLBr_02300|M.leprae_Br4923 TQA---TIEREHRDADTPAALAGPREHANLPPCP-DAGSGPGPAVLRGVV
MMAR_5161|M.marinum_M TGA---PVAREHRDADTPAALAGPRRRANLPPCP-AGGAGPGPARLQGVV
MUL_4247|M.ulcerans_Agy99 TGA---PVAREHRDADTPAALAGPRRRSNLPPCP-AGGAGPGPARLQGVV
MAV_0456|M.avium_104 PATGRVVADREHRDADTPAALAGPRQRADLPPCP-AAGTGPGPAALRGVT
MSMEG_6186|M.smegmatis_MC2_155 EAP--SATARDHRDADTPEALAEPRARADLPPCP-GPGNGQGPEALRGMT
Mvan_5432|M.vanbaalenii_PYR-1 QRD--AISARDRRDADTPEALAGLRARAALEPCPTGGDAGPGPETLRGIE
MAB_0419|M.abscessus_ATCC_1997 GQQ--QVAARERRDAETPEALAELRRQAQLPSCP-AANPDPGTPALAGIT
Mflv_2864|M.gilvum_PYR-GCK GPG-LTLPAAAVGDADT-GELARLTARAALAPCPTPREGAPPKGDLAGAL
TH_2251|M.thermoresistible__bu AQG-------------GTFEFVAPGGQTDIFYDPPADRGRPGP--ISGPD
:. :: : * : *
Mb3697c|M.bovis_AF2122/97 VVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMA-EYQRRVGP
Rv3673c|M.tuberculosis_H37Rv VVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMA-EYQRRVGP
MLBr_02300|M.leprae_Br4923 LECASDGFAVDVARALAGRRVVLNLWASWCASCLGELPAMV-EYQRRVGS
MMAR_5161|M.marinum_M VECAANGAPVDVASAVAGRRVLLNLWAYWCAECTAELPALA-EYQRRVGS
MUL_4247|M.ulcerans_Agy99 VECAANGAPVDVASAVAGRRVLLNLWAYWCAECTAELPALA-EYQRRVGS
MAV_0456|M.avium_104 AECAADGSVVDAGRAVAGRRVVLNFWAYWCAPCAAELPAMA-EYQRRAGA
MSMEG_6186|M.smegmatis_MC2_155 LECAGDGDPVDVAAALAGRPVVLNLWAYWCGPCADELPAMA-EYQRRN-P
Mvan_5432|M.vanbaalenii_PYR-1 LECVGDGSRVDVAEAVAGRPVVLNLWAYWCGPCADELPAMA-EYQRRVGS
MAB_0419|M.abscessus_ATCC_1997 LECS--GVRVPVGPVLAGRQVVLNLWAYWCGPCADELPAMA-ELQRRAGD
Mflv_2864|M.gilvum_PYR-GCK ASCLGARTMFDVGAALAGEQTLINLWASWCAPCREEIPVLD-AYAGQP-G
TH_2251|M.thermoresistible__bu LMNPDETISLDD---FAGQVVVINIWGQWCGPCRTEILELQQVYDATRHQ
. .**. .::*:*. **. * *: :
Mb3697c|M.bovis_AF2122/97 AVLVVTVHQ-GQNEAAALSRLADLGVRLPTLQDDRRRVAAALR---VANV
Rv3673c|M.tuberculosis_H37Rv AVLVVTVHQ-GQNEAAALSRLADLGVRLPTLQDDRRRVAAALR---VANV
MLBr_02300|M.leprae_Br4923 DVMVVTVHQ-DENEMAALLRLAQLGVRLPTLQDGRRRVAAAFG---VANV
MMAR_5161|M.marinum_M EVTVLTVHQ-DENEAAALVELADLGVRLPTLQDGRRKVAAALG---VANV
MUL_4247|M.ulcerans_Agy99 EVTVLTVHQ-DENEAAALVELADLGVRLPTLQDGRRKVAAALG---VANV
MAV_0456|M.avium_104 EVTVLTVHQ-DENETAALLRLAELGVRLPTLQDGRRRVAAALR---VVNV
MSMEG_6186|M.smegmatis_MC2_155 DVLVLTVHQ-DENETAALLRLAELGVRLPTLQDGRRLVAAALK---VPNV
Mvan_5432|M.vanbaalenii_PYR-1 AVTVLTVHQ-DENESAALLRLTELGVHLPTLQDGRRTIAAALQ---VPNV
MAB_0419|M.abscessus_ATCC_1997 KLTVITVHQ-DENEAAGLNRLAELHVRLPMIQDGARRIAAALK---SPNV
Mflv_2864|M.gilvum_PYR-GCK AVRVVGMNV-QDTDTVALSLLADLGVHYPSFGN-ADAVGQVLG---APPV
TH_2251|M.thermoresistible__bu GVAFLGIDVRDNNIDAAQDFIADRNITFPSIYDPPMRTMIAFGGRYPTTV
: .: :. :. .. ::: : * : : .: *
Mb3697c|M.bovis_AF2122/97 MPATVVLRPDGSVAQT-LPRAFGS-----ADEIVAAVGNDAG---
Rv3673c|M.tuberculosis_H37Rv MPATVVLRPDGSVAQT-LPRAFGS-----ADEIVAAVGNDAG---
MLBr_02300|M.leprae_Br4923 IPTTVVLRPDGSVAQT-LPRALVS-----VDQIAAAVGNDTG---
MMAR_5161|M.marinum_M MPATVLLRPDGSVAQT-LPRAFGS-----ADEIAAAVGNPA----
MUL_4247|M.ulcerans_Agy99 MPATVLLRPDGSVAQT-LPRAFGS-----ADEIAAAVENPA----
MAV_0456|M.avium_104 MPATVVLRPDGSVAQT-LPRAFST-----ADEIAAAIGNDRG---
MSMEG_6186|M.smegmatis_MC2_155 MPATVVLRPDGSVAEI-LPRSFVD-----ADEIAAAVDELIRSSR
Mvan_5432|M.vanbaalenii_PYR-1 MPATVVLRADGSVAEI-LPRSFAT-----ADEIAAAVDPKIGAA-
MAB_0419|M.abscessus_ATCC_1997 MPTTILIRADGSVAQV-LPRSFTS-----ADEIGAEVEQALGMRF
Mflv_2864|M.gilvum_PYR-GCK LPLSYLVGTDGTVRRVTTPTVFRD-----VEQVRAAVAAMNP---
TH_2251|M.thermoresistible__bu IPSTVVLDREHRVAAVFLRELLAEDLQPVVERLAAEDPAPDGDAS
:* : :: : * : .:.: *