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MSTELPADRLRRRLGSDPDTAEDDAPDTSLSRWLPADEPSGPSAWLTRIRADPGRAGVIALGVVGVVAVL VTVLTLIGDSPPAVVSAKLPPVDMASSAAPGAPAPAEPVVVSVVGLVHTPGLVTLPPGSRIADALDAAGG ALDGADMLGLNMARRVADGEQIVVGLGAPPGQPTRMGSAVVADAGSPGGGAMPENSPGSPGLVDLNSATV EQLDTLPGVGPVTAAAIVAWRDANGRFTSVDQLGDVDGIGPARLDKLRDLVRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2662 | - | - | 100% (263) | helix-hairpin-helix repeat-containing competence protein ComEA |
| M. gilvum PYR-GCK | Mflv_3444 | - | 4e-06 | 37.84% (74) | RNA-binding S1 domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3843 | - | 6e-06 | 30.20% (202) | hypothetical protein Mflv_3843 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2438c | - | 4e-85 | 59.20% (299) | hypothetical protein Mb2438c |
| M. tuberculosis H37Rv | Rv2415c | - | 2e-84 | 58.86% (299) | hypothetical protein Rv2415c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1626 | - | 2e-72 | 56.20% (258) | hypothetical protein MAB_1626 |
| M. marinum M | MMAR_3736 | comEA | 3e-82 | 60.07% (293) | membrane protein ComEA |
| M. avium 104 | MAV_1767 | - | 8e-83 | 59.09% (286) | helix-hairpin-helix repeat-containing competence protein ComEA |
| M. smegmatis MC2 155 | MSMEG_4574 | - | 5e-90 | 63.21% (280) | DNA-binding protein |
| M. thermoresistible (build 8) | TH_2831 | - | 1e-16 | 41.67% (120) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3680 | comEA | 1e-80 | 58.70% (293) | membrane protein ComEA |
| M. vanbaalenii PYR-1 | Mvan_3915 | - | 1e-114 | 78.52% (270) | helix-hairpin-helix repeat-containing competence protein ComEA |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2662|M.gilvum_PYR-GCK ------------MSTELPADRLRRRL------------------------
Mvan_3915|M.vanbaalenii_PYR-1 ------------MSTELPAERLRRRL------------------------
Mb2438c|M.bovis_AF2122/97 ------------MRTELPAERLQRRLGAVPDIDSHAA---------SAHL
Rv2415c|M.tuberculosis_H37Rv ------------MRTELPAERLQRRLGAVPDIDSHAA---------SAHL
MAV_1767|M.avium_104 ------------MRTELPAERLQRRLRAEPDAD--------------AAV
MMAR_3736|M.marinum_M ------------MRTELPAERLQRRLSTAPDLR----------------L
MUL_3680|M.ulcerans_Agy99 ------------MRTELPAERLQRRLTTAPDLR----------------L
MAB_1626|M.abscessus_ATCC_1997 ------------MEPELLHRRLAPAGREFDDDD--------------DDD
MSMEG_4574|M.smegmatis_MC2_155 MVRSGAGPTVAGMGTELPVQRLRRRLGSDTDAT-----------------
TH_2831|M.thermoresistible__bu ------------MRTELPAARLYRRLGAGHHPDSGSGRTDTGEDRGEDRG
* .** **
Mflv_2662|M.gilvum_PYR-GCK ------GSD--PDTAED-DAPDTSLSRWLPAD-EPSGPSAWLTRIRADPG
Mvan_3915|M.vanbaalenii_PYR-1 ------GADGHADTGDDEDPPDTTLSRWLPAS-APGGPSALMARVRADPG
Mb2438c|M.bovis_AF2122/97 DPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD---TSRGQGWADRIRADPG
Rv2415c|M.tuberculosis_H37Rv DPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD---TSRGQGWADRIRADPG
MAV_1767|M.avium_104 QPEEPGPIAG---EDFPDDDQNSLLPRWLPG---APEHRGWVARIRADPG
MMAR_3736|M.marinum_M HAESGAAESGADPHDDRDDDPNSLLPRWLPE---AGDGSGLLSRVRADPG
MUL_3680|M.ulcerans_Agy99 HAESGAAESGADPHDDRDDDPNSLLPRWLSE---AGDGSGLLSRVRADPG
MAB_1626|M.abscessus_ATCC_1997 DDDEDDDEDEDLARAAAGSEPESAL-RWLPDSLTAGGTRGWLESVRTDPG
MSMEG_4574|M.smegmatis_MC2_155 TDTIDAADAGDTEDSESGVAPDTALSKWLPDT-TEGQRPAWLNVIRADPG
TH_2831|M.thermoresistible__bu EERGEDRGEEGTAANESGTAPDAVLSKWLPDN-TDGASGGWLAAIRADPG
:: * :**. . :*:***
Mflv_2662|M.gilvum_PYR-GCK RAGVIALGVVGVVAVLVTVLTLIGDSPPAVVSAKLPPVDMAS-----SAA
Mvan_3915|M.vanbaalenii_PYR-1 RAGVVALGVIGIVAVLVTVLSLIRDSPPAVVSAKLPPVEMVS-----SPA
Mb2438c|M.bovis_AF2122/97 RAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS---PTNPR
Rv2415c|M.tuberculosis_H37Rv RAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS---PTNPR
MAV_1767|M.avium_104 RAGAIGLAIVAALAVLVTVFTLIRDRPAPVMSAKLPPVEKVS---TASPR
MMAR_3736|M.marinum_M RAGAIALAVVAALAVLVTAFTLLRDRPAPVMSAKLPAVEHVSGSSGASPG
MUL_3680|M.ulcerans_Agy99 RAGAIALAVVAALAVLVTAFTLLHDRPAPVMSAKLPAVEHVSGSSGASPG
MAB_1626|M.abscessus_ATCC_1997 RAGVVALGAIGVLAVLVTVFTVMRQPPAPVS-ANLPPVQPVS----SSSV
MSMEG_4574|M.smegmatis_MC2_155 RVGVLALATLGVLAVLITVFVVLRDRPAPVMSANLPPVQMVS---SSAPT
TH_2831|M.thermoresistible__bu RAGAVALVAVGVTAVLITIFALVRDETPPVMSANXX--------------
*.*.:.* :. ***:* : :: : . .* *:
Mflv_2662|M.gilvum_PYR-GCK PGA----PAPAE----PVVVSVVGLVHTPGLVTLPPGSRIADALDAAGGA
Mvan_3915|M.vanbaalenii_PYR-1 PGAGPAAPGPAG----PVVVSVVGLVHTPGLVTLAPGARIADALDAAGGA
Mb2438c|M.bovis_AF2122/97 SSASP---GSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGA
Rv2415c|M.tuberculosis_H37Rv SSASP---GSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGA
MAV_1767|M.avium_104 SSASPS--GGPDR---PVVVSVVGLVHTPGLVTLAPGARIADAVQAAGGA
MMAR_3736|M.marinum_M SSASPAAAAGPDR---PVVVSVVGLVHTPGLFTLAPGARVADALQAAGGA
MUL_3680|M.ulcerans_Agy99 SSASPAAAAGPDR---PVVVSVVGLVHTSGLFTLAPGARVADALQAAGGA
MAB_1626|M.abscessus_ATCC_1997 SAPSS------------LVISVVGLVKRPGLVTLATGARVADAVTAAGGA
MSMEG_4574|M.smegmatis_MC2_155 PEAAAG----------PVVVSVVGLVHKPGLVTLSSGARIADALTAAGGA
TH_2831|M.thermoresistible__bu --------------------------------------------------
Mflv_2662|M.gilvum_PYR-GCK LDGADMLGLNMARRVADGEQIVVGLGAPPGQPTRMGSAVVADAGSPGGGA
Mvan_3915|M.vanbaalenii_PYR-1 LDGADVLGLNMARRVADGEQIVVGIGAPAGQPTEMGSSIVSQAAEPG-AA
Mb2438c|M.bovis_AF2122/97 VDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTS
Rv2415c|M.tuberculosis_H37Rv VDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTS
MAV_1767|M.avium_104 VNGADTAGLNMARPLDDGEQIVVGLAPVPGQPPVLGSSVAAGST-PAPKP
MMAR_3736|M.marinum_M LAGADTIGLNMARQLADGEQIVVGLAPVAGQPKRFGSSIGAATPSPAPAA
MUL_3680|M.ulcerans_Agy99 LAGADTIGLNMARQLADGEQIVVGLAPVAGQPKRFGSSIGAATPSPAPAA
MAB_1626|M.abscessus_ATCC_1997 VDGADVITLNMARPVADGDQIVVGLAPVPGQPVGMASSIVAAGQTPAGST
MSMEG_4574|M.smegmatis_MC2_155 LDGADLIGLNMARRVADGEQIVVGIAAPAGQPTTMGSSVSTAEATGAAEP
TH_2831|M.thermoresistible__bu -----------------------XVGRPPAHPR--HSS------------
:. ..:* *:
Mflv_2662|M.gilvum_PYR-GCK MPEN-----SPGSPGLVDLNSATVEQLDTLPGVGPVTAAAIVAWRDANGR
Mvan_3915|M.vanbaalenii_PYR-1 SPQT-----PAASTGLVDLNTATAEQLDTLPGVGPVTAAAILAWRDANGR
Mb2438c|M.bovis_AF2122/97 GTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGR
Rv2415c|M.tuberculosis_H37Rv GTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGR
MAV_1767|M.avium_104 PPGPGAAKAKPKTSDAVDLNTATVQELDALPGVGPVTAAAIVAWRQTNGR
MMAR_3736|M.marinum_M TSGTRSP--GPNPAEVLDLNTATVEQLDSLPGVGPVTAAAIVSWRAANGK
MUL_3680|M.ulcerans_Agy99 TSGTRSP--GPNLAEVLDLNTATVEQLDSLPGVGPVTAAAIVSWRAANGN
MAB_1626|M.abscessus_ATCC_1997 GSK------GPGAPGRVNLNTATESELDALPGVGPVMAASIVRWRSEHGK
MSMEG_4574|M.smegmatis_MC2_155 AAGGG----GQTASGPLDLNTATVEQLDALPGVGPVTAEAIVSWRNANGQ
TH_2831|M.thermoresistible__bu --------------------------------------------------
Mflv_2662|M.gilvum_PYR-GCK FTSVDQLGDVDGIGPARLDKLRDLVRV
Mvan_3915|M.vanbaalenii_PYR-1 FSSVEQLGDVDGIGPARLDKLRALVRV
Mb2438c|M.bovis_AF2122/97 FTSVDQLADVDGIGPARLDKLRNLVRV
Rv2415c|M.tuberculosis_H37Rv FTSVDQLADVDGIGPARLDKRRNLVRV
MAV_1767|M.avium_104 FTSVDQLADVEGIGPARLEKLRALVRV
MMAR_3736|M.marinum_M FTSVDQLAEVDGIGPARLQKLRSLVRV
MUL_3680|M.ulcerans_Agy99 FTSVDQLAEVDGIGPARLQKLRSLVRV
MAB_1626|M.abscessus_ATCC_1997 FTSIDQLAEVDGIGPSRLDKLRDFVVL
MSMEG_4574|M.smegmatis_MC2_155 FASVDQLGEVDGIGPARLEKLRGLVRV
TH_2831|M.thermoresistible__bu ---------------------------