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M. gilvum PYR-GCK Mflv_2144 (-)

PGELAIALTAALILLAVAAVVVAVRTRRVVATPTERAVHAALHTASLAARALRQGLDTDSAKTSAPFLRE
LTGTDGLALFGGDGALLARDPDDDAVWPPDVRDACDGAARQSISGGRRVMTHARTSAVVAQPMLTETGDL
LGVLVVVTTRSPGPGMLGAVGEVARYAASQIELAELDASRARLDRAEVLALRAQISPHFIYNALNTIASF
VRTDPDRARELILEFADFTRYSFRAAGQFTTLSDELRNIDRYLTLERARFGTALKVTLRVAPEVLNVVVP
FLALQPLVENAVRHGFAGRGSGSIELVARDEGSDCVITVEDDGVGMDPDALRSGPSDALSAGDAEPEGTG
AHVGLTNVDHRLRAAFGNDYGLVVETAIGAGTKVIMRVPKFRSGVRASGGGFGVGTK*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_2144	-	-	100% (408)	signal transduction histidine kinase, LytS
M. gilvum PYR-GCK	Mflv_1743	-	2e-05	30.06% (163)	integral membrane sensor signal transduction histidine kinase

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. avium 104	MAV_0147	-	1e-05	24.61% (256)	sensor-type histidine kinase PrrB
M. smegmatis MC2 155	MSMEG_5158	-	1e-179	80.35% (402)	sensor histidine kinase
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_4559	-	0.0	91.38% (406)	signal transduction histidine kinase, LytS

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2144|M.gilvum_PYR-GCK          -----MPGELAIALTAALILLAVAAVVVAVRTRRVVATPTERAVHAALHT
Mvan_4559|M.vanbaalenii_PYR-1       -----MSGELAIALTAALILLAVAAVVLAVRTRRVVATPTERAVHAALHT
MSMEG_5158|M.smegmatis_MC2_155      -----MSGEVAIALALALVLTAVVAIVV-VRTRRVVATPTERAVHAALHT
MAV_0147|M.avium_104                MRVLSLRTIVIVAAISVMTLVVLLGTWVWVGVTNDQYNQLDRRLDSVSSL
                                         :   : :*   .: * .: .  : * . .   .  :* :.:.   

Mflv_2144|M.gilvum_PYR-GCK          ASLAARALRQGLDTDSAKTSAPFLRELTGTDGLALFGGDGALLARDPD--
Mvan_4559|M.vanbaalenii_PYR-1       ASLAARALRQGLNTDSAQTAAPFLRDLTGADGLALFDGDGAVLAEDAL--
MSMEG_5158|M.smegmatis_MC2_155      ASSAARALRRGLDTDSAQTAAPYLRGLTVTQGLALFDGDGQLLALDPD--
MAV_0147|M.avium_104                GDISSLLTNPQHNSPDRATQDGNLVRTARIGGVTVSVPSNIVLPQLPDGY
                                    .. ::   .   :: .  *    *   :   *:::   .. :*.  .   

Mflv_2144|M.gilvum_PYR-GCK          -DDAVWPPDVRDACDGAARQSISGGRRVMTHARTSAVVAQPMLTETGDLL
Mvan_4559|M.vanbaalenii_PYR-1       -DDALWDDDVRDACDDAAHESISGQRRVMAHAGTSAVVAQPLLAESGDLL
MSMEG_5158|M.smegmatis_MC2_155      -DDALWQTDIVDTCTSTARDSIADQRRKLTSARPMTVVAQPLLTEAGDVL
MAV_0147|M.avium_104                ANTTINGVQYRVRTFTAGPASIALAAPLAEAQHRINELHLRVLLICASVI
                                     : ::   :       :.  **:              :   :*   ..::

Mflv_2144|M.gilvum_PYR-GCK          G----VLVVVTTRSPGPGMLGAVGEVARYAASQIELAELDASRARLDRAE
Mvan_4559|M.vanbaalenii_PYR-1       G----VLVVVTTRSPGPGMLGAVGEVARYAASQIELAELDASRARLDRAE
MSMEG_5158|M.smegmatis_MC2_155      G----ALVVVTASTPGPGMLGAVGEVARYAASQIELAELDASRARLDRAE
MAV_0147|M.avium_104                GGTVVVGWVISLIMVNPFLLLAQQARAINAQSSPDEVQVRGVREAVEIAE
                                    *    .  *::    .* :* *    *  * *. : .:: . *  :: **

Mflv_2144|M.gilvum_PYR-GCK          VLA---LRAQISPHFIYNALNTIASFVRTDPDRARELILEF---------
Mvan_4559|M.vanbaalenii_PYR-1       VLA---LRAQISPHFIYNALNTIASFVRTDPDRARELILEF---------
MSMEG_5158|M.smegmatis_MC2_155      VLA---LRAQISPHFIYNALNTIASFVRTDPDRARELILEF---------
MAV_0147|M.avium_104                AVEGMLARIGKEQQRTKAALESARDFAAVASHELRTPLTAMRTNLEVLST
                                    .:     *   . :    **::  .*. . ... *  :  :         

Mflv_2144|M.gilvum_PYR-GCK          ------------ADFTRYSFRAAGQFTTLS----DELRNIDRYLTLER-A
Mvan_4559|M.vanbaalenii_PYR-1       ------------ADFTRYSFRAAGQFTTLA----EELRNIDRYLTLER-A
MSMEG_5158|M.smegmatis_MC2_155      ------------ADFTRYSFRAAGQYTTLA----DELRNIDRYLTLER-A
MAV_0147|M.avium_104                LDLPHEQRQEVIGDVIRTQSRIEATLTALERLAQGELTTVDDFVPFDITE
                                                .*. * . *  .  *:*      ** .:* ::.::   

Mflv_2144|M.gilvum_PYR-GCK          RFGTALKVTLRVAPEVLNVVVP---------FLALQPLVENAVRHGFAGR
Mvan_4559|M.vanbaalenii_PYR-1       RFGTALKVTLQVAPEVLNVVVP---------FLALQPLVENAVRHGFAGR
MSMEG_5158|M.smegmatis_MC2_155      RFGQSLKVRLQVAPEVLNVVVP---------FLALQPLVENAVRHGLAGQ
MAV_0147|M.avium_104                LLDRAAHDALRVYPDVEVSLVPSPTVLMIGLPTGLRLVIDNAIANAVKHG
                                     :. : :  *:* *:*   :**           .*: :::**: :..   

Mflv_2144|M.gilvum_PYR-GCK          GSGSIELVARDEGSDCVITVEDDGVGMDPDALRSGPSDALSAGDAEPEGT
Mvan_4559|M.vanbaalenii_PYR-1       GSGSIELVARDEGSDCVITVEDDGVGMDPDALRSGPGDALSDGAPASEGA
MSMEG_5158|M.smegmatis_MC2_155      GGGTVEIIARDEGTDCVITVEDDGAGMDPETLRAGQGDALAD----RTDQ
MAV_0147|M.avium_104                NAGKIQLTVSSSGEGVEIAIDDDGSGIP-ESERATVFERFARG-STASRS
                                    ..*.::: . ..* .  *:::*** *:  :: *:   : ::         

Mflv_2144|M.gilvum_PYR-GCK          GAHVGLTNVDHRLRAAFGNDYGLVVETAIGAGTKVIMRVPKFRSGVRASG
Mvan_4559|M.vanbaalenii_PYR-1       GAHVGLTNVDHRLRAAFGNDYGLVVETAIGAGTKVIMRVPKFRSGVRASG
MSMEG_5158|M.smegmatis_MC2_155      GAHVGLTNVDHRLRAAFGNDYGLVVETALGAGTKVMMRVPKFRSGVHAGG
MAV_0147|M.avium_104                GSGLGLALVAQQAELHGG---TAELQNSPLGGTRLLLRLAGDGRGPA---
                                    *: :**: * :: .   *      ::.:  .**::::*:.    *     

Mflv_2144|M.gilvum_PYR-GCK          GGFGVGTK-
Mvan_4559|M.vanbaalenii_PYR-1       GGFVVGRNE
MSMEG_5158|M.smegmatis_MC2_155      GAFG-----
MAV_0147|M.avium_104                ---------