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DDITTTPSRLSTPARNVDATLDVGLLVLRLGLGAALLHAAFLKLSDFPTTIQFMADAGWRLPAFAAFMVT ATETLAGIGVVLGVMTPLAASAGLGAMLCAWAVNVSAGAVWEDPFNAPFLIGLGAATLLATGAGGYAVDA RVLSRFSWSPRVKVILLVLAFVTAVVTWVALYGVNPIHFGAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2130 | - | - | 100% (183) | DoxX family protein |
| M. gilvum PYR-GCK | Mflv_4241 | - | 7e-10 | 26.04% (192) | DoxX family protein |
| M. gilvum PYR-GCK | Mflv_2112 | - | 2e-07 | 28.91% (128) | DoxX family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3030c | - | 4e-11 | 27.75% (173) | hypothetical protein Mb3030c |
| M. tuberculosis H37Rv | Rv3005c | - | 4e-11 | 27.75% (173) | hypothetical protein Rv3005c |
| M. leprae Br4923 | MLBr_01698 | - | 5e-11 | 28.42% (183) | hypothetical protein MLBr_01698 |
| M. abscessus ATCC 19977 | MAB_1276c | - | 7e-12 | 30.95% (168) | hypothetical protein MAB_1276c |
| M. marinum M | MMAR_1707 | - | 2e-11 | 26.70% (191) | hypothetical protein MMAR_1707 |
| M. avium 104 | MAV_3854 | - | 8e-11 | 32.00% (175) | DoxX subfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_5179 | - | 1e-47 | 53.37% (178) | DoxX subfamily protein, putative |
| M. thermoresistible (build 8) | TH_4069 | - | 3e-11 | 27.23% (191) | PUTATIVE DoxX family protein |
| M. ulcerans Agy99 | MUL_1944 | - | 1e-11 | 26.70% (191) | hypothetical protein MUL_1944 |
| M. vanbaalenii PYR-1 | Mvan_4574 | - | 6e-67 | 72.22% (162) | DoxX family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01698|M.leprae_Br4923 MTGQSHDEHWRRPGECPEPIPGRPASASLVDPEDDLTPVGYPGDF----G
MAV_3854|M.avium_104 MTSQPNDAHWQRPGESPEPTPGRPASARLVDPEDDLTPVGYPGDFNPSTG
Mb3030c|M.bovis_AF2122/97 MTS-SNDSHWQRPDDSPGPMPGRPVSASLVDPEDDLTPARYAGDFG--SG
Rv3005c|M.tuberculosis_H37Rv MTS-SNDSHWQRPDDSPGPMPGRPVSASLVDPEDDLTPARYAGDFG--SG
MMAR_1707|M.marinum_M MTS-SNDSRWQRPDDSPGPIPGRPVTASLVDPEDDLTPAKYSSDFGS-AG
MUL_1944|M.ulcerans_Agy99 MTS-SNDSRWQRPDDSPGPIPGRPVTASLVDPEDDLTPAKYSSDFGS-AG
TH_4069|M.thermoresistible__bu ---------------------VRPASASLVDPEDDLSST-YGGDIE----
MAB_1276c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2130|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4574|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5179|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01698|M.leprae_Br4923 TTTVIPYSDPDHLKGPGGTGYNLLDQQEPLPYVQPQ--------------
MAV_3854|M.avium_104 TTTVIPYGGAAAVAGSGAAGYHLLEQQEPLPYVQPHSA------------
Mb3030c|M.bovis_AF2122/97 TTTVIPPYDAASS-GVGNSGYSLIEAAEPLPYVQPQPG------------
Rv3005c|M.tuberculosis_H37Rv TTTVIPPYDAASS-GVGNSGYSLIEAAEPLPYVQPQPG------------
MMAR_1707|M.marinum_M TTTVIPPYDPTNS-GAVPSGYNLMDAQEPLPYVQPQPG------------
MUL_1944|M.ulcerans_Agy99 TTTVIPPYDPTNS-GAVPSGYNLMDAQEPLPYVQPQPG------------
TH_4069|M.thermoresistible__bu -TTAIPSYPSTGT-ASAQSPFALTGEPEPLPYVQPDDGSSFANYSAGAAS
MAB_1276c|M.abscessus_ATCC_199 -------------------------MPSAKQYSDPLTR------------
Mflv_2130|M.gilvum_PYR-GCK -----------------------MDDITTTPSR-----------------
Mvan_4574|M.vanbaalenii_PYR-1 -----------------------MNDTPSREAAHALAL------------
MSMEG_5179|M.smegmatis_MC2_155 -----------------------MTANFMEKTS-----------------
MLBr_01698|M.leprae_Br4923 -----------ARHAVAEPTEIDSDQ-DNERLHTVGRRGTQHLGLLVLRV
MAV_3854|M.avium_104 -----------ARHAAPEPTDDD-DE-HHDRLLDVGRRGTQHLGLLVLRA
Mb3030c|M.bovis_AF2122/97 ------------RQVPAGSAGIDMD--DDERVRAAGRRGTQNLGLLILRV
Rv3005c|M.tuberculosis_H37Rv ------------RQVPAGSAGIDMD--DDERVRAAGRRGTQNLGLLILRV
MMAR_1707|M.marinum_M -----------ARHIPATPAALDMDE-DDERIRAASRRGTQNFGLLILRV
MUL_1944|M.ulcerans_Agy99 -----------ARHIPATPAALDMDE-DDERIRAASRRGTQNFGLLILRV
TH_4069|M.thermoresistible__bu SFSTGPASSFPAGSFPAGPAEVGTDELTEDRIKAAGRRGTMDLGLMLIRV
MAB_1276c|M.abscessus_ATCC_199 ----------------------------------------NDIGLLVLRV
Mflv_2130|M.gilvum_PYR-GCK ----------------------------LSTPAR-NVDATLDVGLLVLRL
Mvan_4574|M.vanbaalenii_PYR-1 -------------------------AEMAETDADGSTAGTRDIGLLILRL
MSMEG_5179|M.smegmatis_MC2_155 ----------------------------LSSGATSSARSMTDTGLLILRL
. **:::*
MLBr_01698|M.leprae_Br4923 GLGVVLAAQGLHKLFGWWGGQGLTGFKNSLTQVGYQHADILAYVSAGGEA
MAV_3854|M.avium_104 GLGVVLGAHGLQKLFGWWGGSGVTGLRNSLSDVGYQHADILAYVSAGGEL
Mb3030c|M.bovis_AF2122/97 GLGAVLIAHGLQKLFGWWDGQGLAGFQNSLSDIGYQHAEILAYVSAGGEI
Rv3005c|M.tuberculosis_H37Rv GLGAVLIAHGLQKLFGWWDGQGLAGFQNSLSDIGYQHAEILAYVSAGGEI
MMAR_1707|M.marinum_M GLGAVLIAHGLQKLFGWWGGSGVTAFKNSLSDVGFQHADILAYVGAGGEI
MUL_1944|M.ulcerans_Agy99 GLGAVLIAHGLQKLFGWWGGSGVTAFKNSLSDVGFQHADILAYVGAGGEI
TH_4069|M.thermoresistible__bu GLGALLVVHGLQQAFGWWGGDGLGGLRDALTESGFRYAEALTYAVAGAQI
MAB_1276c|M.abscessus_ATCC_199 AVGLTLCWDGLNVVF-------ASEQFKQLGSTAGASADLAARVLAGTYS
Mflv_2130|M.gilvum_PYR-GCK GLGAALLHAAFLKLSD------FPTTIQFMADAGWRLPAFAAFMVTATET
Mvan_4574|M.vanbaalenii_PYR-1 GVGAALVQAGLIKVAD------FSMTVQFMTEAGWRLPAFAAFMVTATET
MSMEG_5179|M.smegmatis_MC2_155 ALGATMLQAGLIKAAD------FSTTAGFMESGGWSLPTFAALMVTTAET
.:* : .: : . . . : :
MLBr_01698|M.leprae_Br4923 VAGVLLVLGLFAPVVAAGALAFLINGLLA---AWPHSPLFSFFLPDGNEH
MAV_3854|M.avium_104 VAGVLLVLGLFTPLAAAGALAFLINGLLATISARPHAHTFSFFLPQGHEY
Mb3030c|M.bovis_AF2122/97 VAGVLLVLGLFTPLAAAGALAFLINGLLAGISAQHSR-PVAYFLQDGHEY
Rv3005c|M.tuberculosis_H37Rv VAGVLLVLGLFTPLAAAGALAFLINGLLAGISAQHSR-PVAYFLQDGHEY
MMAR_1707|M.marinum_M VVGVLLVLGLFTPLAGAGALAFLINGTLANVSARPHS-QFSYFLPDGHEY
MUL_1944|M.ulcerans_Agy99 VVGVLLVLGLFTPLAGAGALAFLMNGTLANVSARPHS-QFSYFLPDDHEY
TH_4069|M.thermoresistible__bu GAGVLLVLGLFTPLAAAGALAYLINVLLAGISANNGA--LPFFLPEGYEF
MAB_1276c|M.abscessus_ATCC_199 IGGALLVAGLLTPLGGCAVLGSMLYAATLSYSVRHDL----LQSGTAVQF
Mflv_2130|M.gilvum_PYR-GCK LAGIGVVLGVMTPLAASAGLGAMLCAWAVNVSAGAVW-------EDPFNA
Mvan_4574|M.vanbaalenii_PYR-1 LSGVALLLGVLTPLAGSAALGAMLCAWAVNVSAAAFW-------SEPFNV
MSMEG_5179|M.smegmatis_MC2_155 LGGLGLLFGVLTPLAACAVIGAMVDAWAVNVSTDVVW-------AMPFNV
* :: *:::*: ... :. :: . :
MLBr_01698|M.leprae_Br4923 QITLIVMDVTVILCGPGRYGLDAGRR-WAYRPFIGSFIVLIAGIAAGIAV
MAV_3854|M.avium_104 QITLIVMATAVILCGPGRYGLDARRG-WAHRPFIGSFVALLAGIAAGVGV
Mb3030c|M.bovis_AF2122/97 QITLVVMAVAVILSGPGRYGLDAARG-WAHRPFIGSFVALLGGIAAGIAV
Rv3005c|M.tuberculosis_H37Rv QITLVVMAVAVILSGPGRYGLDAARG-WAHRPFIGSFVALLGGIAAGIAV
MMAR_1707|M.marinum_M QITLVVMAVAVILSGPGRYGLDAGRG-WAHRPFIGSFVALLTGIAAGIAI
MUL_1944|M.ulcerans_Agy99 QITLVVMAVAVILSGPGRYGLDAGRG-WAHRPFIGSFVALLTGIAAGIAI
TH_4069|M.thermoresistible__bu EITLIVVAAALVLTGPGRYGLDAGRG-WARRPFIGSFLALLLGVGAGIAI
MAB_1276c|M.abscessus_ATCC_199 PLLLAAAAMAVILMGPGRISVDGRFG-REEWPNAVTSVLVVAGFGAAIAA
Mflv_2130|M.gilvum_PYR-GCK PFLIGLGAATLLATGAGGYAVDARVLSRFSWSPRVKVILLVLAFVTAVVT
Mvan_4574|M.vanbaalenii_PYR-1 PFLIGLGAAALIFTGAGGYSVDARLVTRLPWSTRVRVALLVLAFAVAVLT
MSMEG_5179|M.smegmatis_MC2_155 PFLVAFGAATLLFTGSGRWSVDHRVFGRSTVPRPIAVGLLVAGVAVAILT
: : ::: *.* .:* . :: .. ..:
MLBr_01698|M.leprae_Br4923 WVLLNGVNPLA----------
MAV_3854|M.avium_104 WVALNGVNPIG----------
Mb3030c|M.bovis_AF2122/97 WVLLNGANPLA----------
Rv3005c|M.tuberculosis_H37Rv WVLLNGANPLA----------
MMAR_1707|M.marinum_M WVLLNGVNPVA----------
MUL_1944|M.ulcerans_Agy99 WVLLNGVNPVA----------
TH_4069|M.thermoresistible__bu WVLLNGANPLG----------
MAB_1276c|M.abscessus_ATCC_199 WVLVKGTNPLS----------
Mflv_2130|M.gilvum_PYR-GCK WVALYGVNPIHFGAV------
Mvan_4574|M.vanbaalenii_PYR-1 WVALYGVNPIHFTAPPAPPTP
MSMEG_5179|M.smegmatis_MC2_155 WMALNGVNPIHFSAPQG----
*: : *.**: