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MRDTVRAVGLAAALLGWSATAPRLPQEWNPLPHMVFSGAVTLLSRPSLGLRPAQLRRGVRWGSAAAAPVG LGVAAGLMAPAVRAGMAARDLPAAPARWLLLRIPFATVGPEELAYRAVLGDAATRAFGPRVGKLFTAVVF GLSHVPDARAAGDNVPGTVVVTGAAGWVFSWLHESSGSLAAPVLAHLAVNEAGAVAALAVQQRRSGRGRP TGAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1632 | - | - | 100% (215) | abortive infection protein |
| M. gilvum PYR-GCK | Mflv_3342 | - | 8e-17 | 35.26% (173) | abortive infection protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0827 | - | 7e-48 | 49.01% (202) | hypothetical protein Mb0827 |
| M. tuberculosis H37Rv | Rv0804 | - | 7e-48 | 49.01% (202) | hypothetical protein Rv0804 |
| M. leprae Br4923 | MLBr_00644 | - | 4e-05 | 26.42% (159) | hypothetical protein MLBr_00644 |
| M. abscessus ATCC 19977 | MAB_0709 | - | 2e-45 | 50.78% (193) | hypothetical protein MAB_0709 |
| M. marinum M | MMAR_4887 | - | 3e-51 | 54.21% (190) | hypothetical protein MMAR_4887 |
| M. avium 104 | MAV_0745 | - | 1e-49 | 52.74% (201) | caax amino protease family protein |
| M. smegmatis MC2 155 | MSMEG_5821 | - | 3e-46 | 51.26% (199) | caax amino protease family protein |
| M. thermoresistible (build 8) | TH_1367 | - | 1e-16 | 35.26% (173) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0411 | - | 9e-51 | 54.21% (190) | hypothetical protein MUL_0411 |
| M. vanbaalenii PYR-1 | Mvan_5117 | - | 4e-76 | 66.05% (215) | abortive infection protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1632|M.gilvum_PYR-GCK -----------MRDTVRAVGLAAALLGWSATA-PRLPQEWNPLPHMVFSG
Mvan_5117|M.vanbaalenii_PYR-1 -----------MRDGVRATALAMLLLGWSLAA-PRLPQRWNPLPQTMFGA
Mb0827|M.bovis_AF2122/97 ------------MSRLRALSLAAGLVGWSLVS-PRLPAPWRIPLQAGLGS
Rv0804|M.tuberculosis_H37Rv ------------MSRLRALSLAAGLVGWSLVS-PRLPAPWRIPLQAGLGS
MMAR_4887|M.marinum_M ------------------------MVGWSLAS-PRLPARWRVALQAVLGG
MUL_0411|M.ulcerans_Agy99 ------------------------MVSWSLAS-PRLPARWRVALQAVLGG
MAV_0745|M.avium_104 -------MRPSRFRRTAALSLAGALVGWSFVG-PRLPAGARMVLQAGMGA
MSMEG_5821|M.smegmatis_MC2_155 -------MAPMTAAKFRALALAAALTAWNVVVDPRLPERCRPVVRALVGT
MAB_0709|M.abscessus_ATCC_1997 ------------MSGARVLVLAVVLVAWPAVL-ERFPQRWRPLIGAGTST
TH_1367|M.thermoresistible__bu -VVAQLAALSRFRTYVDVAVVVVVLAICNLIAHFTTPWASVATVPAVAVG
MLBr_00644|M.leprae_Br4923 MGMRPAARMPKLTRRSRTLIMVALGVIVLLLAGPRLVDAYVEWLWFGELG
Mflv_1632|M.gilvum_PYR-GCK AVTLLSRPSLG-----LRPAQLRRGVRWGSAAAAPVGL----------GV
Mvan_5117|M.vanbaalenii_PYR-1 GVAALAGAPLG-----LRPPMLWRGLQWGSAAVAPVAL----------SV
Mb0827|M.bovis_AF2122/97 VLVLVTRATMG-----LWPPRLWAGLRLGWAAGAAAAT----------AI
Rv0804|M.tuberculosis_H37Rv VLVLVTRATMG-----LWPPRLWAGLRLGWAAGAAAAT----------AI
MMAR_4887|M.marinum_M LLVLVTRAPLG-----LTPPRLWAGLRLGAVAAAPVAT----------AI
MUL_0411|M.ulcerans_Agy99 LLVLVTRAPLG-----LTPPRLWAGLRLGAVAAAPVAT----------AT
MAV_0745|M.avium_104 ALVALTRAPLG-----LHPPRLWAGLRCGAAVAGCAAG----------AV
MSMEG_5821|M.smegmatis_MC2_155 ALLGLSRAAPGSRRSGLRPPALWSGMRTGSVAAAVVAS----------SV
MAB_0709|M.abscessus_ATCC_1997 ALAGAAGIPLG-----LRPPQLGAGLRLGGIVASAVAA----------AV
TH_1367|M.thermoresistible__bu LVLLVRSRGLGWAELGLSREHWRSGAGYAAAAVALVLS----------VI
MLBr_00644|M.leprae_Br4923 YRSVFSTVLVTRVVVFLVAGLVVGGIVFAGLAVAYRTRPVFVPSHDNDPV
* * . . .
Mflv_1632|M.gilvum_PYR-GCK AAGLMAPAVRAGMAARDLPAAPARWLL-----------------------
Mvan_5117|M.vanbaalenii_PYR-1 AAATTSPPVRAGMVARDLPDPAASWLL-----------------------
Mb0827|M.bovis_AF2122/97 AATTPVPMVRLSMSARELPASVPVWLV-----------------------
Rv0804|M.tuberculosis_H37Rv AATTPVPMVRLSMSARELPASVPVWLV-----------------------
MMAR_4887|M.marinum_M AATTPVPMVRLSMSERDLPASVPGWLG-----------------------
MUL_0411|M.ulcerans_Agy99 AATTPVPMVRLSMSERDLPASVPGWLG-----------------------
MAV_0745|M.avium_104 AATTLVPAVRESMAGREPPAPAPDWLL-----------------------
MSMEG_5821|M.smegmatis_MC2_155 VATTALPAVRTAMRERELPPAVAFWLM-----------------------
MAB_0709|M.abscessus_ATCC_1997 GASPALQPVRASMRARDIDLHPAVWLG-----------------------
TH_1367|M.thermoresistible__bu AIGALLPWTRPMFLNNNYATISGALIASM---------------------
MLBr_00644|M.leprae_Br4923 ARYRAMALSRLRLIGVGIPAAIGLLAGIIAQSYWVRIQLFLHGDNFGIRD
* :
Mflv_1632|M.gilvum_PYR-GCK --LRIPFATVGPEELAYRAVLGDAATRAFGPRVGKLFTAVVFG-------
Mvan_5117|M.vanbaalenii_PYR-1 --LRIPFGTVWSEEATFRAALGATAERAFGRTAGRLFAATVFG-------
Mb0827|M.bovis_AF2122/97 --WHIPGGTVWAEEAAFRGALATIGARAFGRSGGRILQAGAFG-------
Rv0804|M.tuberculosis_H37Rv --WHIPGGTVWAEEAAFRGALATIGARAFGRSGGRILQAGAFG-------
MMAR_4887|M.marinum_M --LQIPFGTVWAEEAAFRAALATMGTRGFGHVGGRLLQAATFG-------
MUL_0411|M.ulcerans_Agy99 --LQIPFGTVWAEEAAFRAALATMGTRGFGHVGGQLLQAVTFG-------
MAV_0745|M.avium_104 --LRIPVGTVWSEEAAFRAALTAAGSAAFGRRSAMLLQAIAFG-------
MSMEG_5821|M.smegmatis_MC2_155 --LGIPLGTVWSEEAAFRGALGAVGTGAFGHTGGRLLQATAFG-------
MAB_0709|M.abscessus_ATCC_1997 --LHIPVGTVWSEELAFRGVLQPLATEAFGRTAGSAVQAMVFG-------
TH_1367|M.thermoresistible__bu --VIIPLQTVIPEELAFRGVLHGALSRAWGFRGVAAAGSLLFG-------
MLBr_00644|M.leprae_Br4923 PQFGKDLGFYAFELPFYRLVLSYVFVAVFLAFVVNLLAHYIFGGIRLSGR
* :* .* : **
Mflv_1632|M.gilvum_PYR-GCK ----------------------------------LSHVPDARAAGDN---
Mvan_5117|M.vanbaalenii_PYR-1 ----------------------------------LSHVPDARAAREP---
Mb0827|M.bovis_AF2122/97 ----------------------------------LSHIADARATGEP---
Rv0804|M.tuberculosis_H37Rv ----------------------------------LSHIADARATGEP---
MMAR_4887|M.marinum_M ----------------------------------LSHVADARATGAP---
MUL_0411|M.ulcerans_Agy99 ----------------------------------LSHVADARATGAP---
MAV_0745|M.avium_104 ----------------------------------LSHIADARAIGEP---
MSMEG_5821|M.smegmatis_MC2_155 ----------------------------------LSHIPDARAAGEP---
MAB_0709|M.abscessus_ATCC_1997 ----------------------------------LAHIRPARAAGDS---
TH_1367|M.thermoresistible__bu ----------------------------------LWHVATSLGLTSSNVG
MLBr_00644|M.leprae_Br4923 TGALSRLARLQLVSLVGVLVLLKAVAYWLDRYELLSRTRSSKPFTGAG--
* : :
Mflv_1632|M.gilvum_PYR-GCK ---------------VPGTVVVTGAAGWVFSWLHESSGSLAAPVLAHLAV
Mvan_5117|M.vanbaalenii_PYR-1 ---------------ILGTVLVTGTAGWAFSWLYAKSGSLVAPMLAHLAV
Mb0827|M.bovis_AF2122/97 ---------------LVLTVLATGIAGWMFGWLADRSGSLAAPLLTHLAI
Rv0804|M.tuberculosis_H37Rv ---------------LVLTVLATGIAGWMFGWLADRSGSLAAPLLTHLAI
MMAR_4887|M.marinum_M ---------------PVPTVLVTGLAGWLFGWLAERSGSLAAPMVLHLAI
MUL_0411|M.ulcerans_Agy99 ---------------PVPTVLVTGLAGWLFGWLAERSGSLAAPMVLHLAI
MAV_0745|M.avium_104 ---------------VAGTVAVTAVGGWFFGWLTDRCGSLAAPMLAHLAV
MSMEG_5821|M.smegmatis_MC2_155 ---------------VVGTVLATGAAGWFLDWLMHRTKSLAAPLLVHLAL
MAB_0709|M.abscessus_ATCC_1997 ---------------IPGTVLVTGMFGWLLGRLRERSGSVVAPMLAHLAL
TH_1367|M.thermoresistible__bu FTRLFGGGVLGTVAGVVLAVIATAVAGFVFDWLRRRSGSLLAPIALHWSL
MLBr_00644|M.leprae_Br4923 --YTDINAVQPAKLILIAIALICAAAVFSAITLRDFRIPAIGLVLLMLSS
. . : * . . : :
Mflv_1632|M.gilvum_PYR-GCK NEAGAVAALAVQQRRSGRGRPTGAAR------------------------
Mvan_5117|M.vanbaalenii_PYR-1 NEAGAVAALAVQRRRSARGRPADGARSPGRRSRS----------------
Mb0827|M.bovis_AF2122/97 NEAGAVAAVLVQRR----SGISTRL-------------------------
Rv0804|M.tuberculosis_H37Rv NEAGAVAAVLVQRR----SGISTRL-------------------------
MMAR_4887|M.marinum_M NEAGAVAALTVQRRWINGAEITPRRRYT----------------------
MUL_0411|M.ulcerans_Agy99 NEAGAVAALTVQRRWINGAEITPRRRYT----------------------
MAV_0745|M.avium_104 NEAGAIAVLAVRRR--SGRNAAPRI-------------------------
MSMEG_5821|M.smegmatis_MC2_155 NEAGALAAVWYARK-------SPRPQ------------------------
MAB_0709|M.abscessus_ATCC_1997 NEAGAVATLYLGRSNVDLSPESASN-------------------------
TH_1367|M.thermoresistible__bu NGMGALAAALVWHLST----------------------------------
MLBr_00644|M.leprae_Br4923 LIVGTGWPLIVEQLIAKPDAVRKESEYIRRSITATRHAYGLTEDVVTYRN
*: :
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 YIGDAPAIAQQIATDHATTSNIRLLDPTIVSPAFTQFQRGKNFYYFPDQL
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 SIDRYLDKKGNLRDYVVAARELNPDRLIDNQRDWINRHTVYTHGNGFIAS
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 PANTVRGIANDPNQNGGYPQFLVNVVGNGTVVSEGPARLDQPRVYFGPVI
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 SNTSADYAIVGKNGDDREYDYETNTDTKRYTYAGSGGVPIGSWLSRSVFA
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 AKFAERNFLFSSVIGSNSKILFNRDPAQRVEAVAPWLTTDSSVYPAIVNK
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 RLVWIIDGYTTLDNYPYSERTSLSSATADSTEVAFNRLAPDKRVAYIRNS
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 VKATVDAYDGAVTLYQQDEYDPVLKVWMKVFPGTVRPKGDITPELAEHLR
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 YPEDLFKVQRMLLAKYHVNDPGTFFNTSDFWDVPLDPNPTASSYQPPYYI
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 VAKNILKNDRSASYQLTSAMNRFKQDFLAAYISASSDPETYGKITVLTIP
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 GNVNGPKLANNAITTDPAVSQDLGVIGRDNQNRIRWGNLLTLPVAQGGLL
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 YVEPVYASPGVSDAASSYPRLIRVAMMYNDKIGYGPTVGDALTGLFGPGA
Mflv_1632|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb0827|M.bovis_AF2122/97 --------------------------------------------------
Rv0804|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4887|M.marinum_M --------------------------------------------------
MUL_0411|M.ulcerans_Agy99 --------------------------------------------------
MAV_0745|M.avium_104 --------------------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0709|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1367|M.thermoresistible__bu --------------------------------------------------
MLBr_00644|M.leprae_Br4923 ASAATGIEPTEAVPPKSPAGSSTPPIAVVPSAPDGSVALSAAKAAALQEI
Mflv_1632|M.gilvum_PYR-GCK -------------------------------------
Mvan_5117|M.vanbaalenii_PYR-1 -------------------------------------
Mb0827|M.bovis_AF2122/97 -------------------------------------
Rv0804|M.tuberculosis_H37Rv -------------------------------------
MMAR_4887|M.marinum_M -------------------------------------
MUL_0411|M.ulcerans_Agy99 -------------------------------------
MAV_0745|M.avium_104 -------------------------------------
MSMEG_5821|M.smegmatis_MC2_155 -------------------------------------
MAB_0709|M.abscessus_ATCC_1997 -------------------------------------
TH_1367|M.thermoresistible__bu -------------------------------------
MLBr_00644|M.leprae_Br4923 QAVIGAAREAQKKGDFVAYGSALQRLDDAITKFNSTK