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M. smegmatis MC2 155 MSMEG_5821 (-)

annotation: caax amino protease family protein
coordinates: 5887175 - 5887831
length: 218

APMTAAKFRALALAAALTAWNVVVDPRLPERCRPVVRALVGTALLGLSRAAPGSRRSGLRPPALWSGMRT
GSVAAAVVASSVVATTALPAVRTAMRERELPPAVAFWLMLGIPLGTVWSEEAAFRGALGAVGTGAFGHTG
GRLLQATAFGLSHIPDARAAGEPVVGTVLATGAAGWFLDWLMHRTKSLAAPLLVHLALNEAGALAAVWYA
RKSPRPQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5821--100% (218)caax amino protease family protein
M. smegmatis MC2 155MSMEG_3612-6e-1333.84% (198) integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0827-1e-5856.25% (208) hypothetical protein Mb0827
M. gilvum PYR-GCKMflv_1632-3e-4651.26% (199) abortive infection protein
M. tuberculosis H37RvRv0804-1e-5856.25% (208) hypothetical protein Rv0804
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0709-1e-4749.27% (205) hypothetical protein MAB_0709
M. marinum MMMAR_4887-8e-5655.10% (196) hypothetical protein MMAR_4887
M. avium 104MAV_0745-1e-5653.70% (216) caax amino protease family protein
M. thermoresistible (build 8)TH_1367-1e-1434.38% (192) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_0411-3e-5554.59% (196) hypothetical protein MUL_0411
M. vanbaalenii PYR-1Mvan_5117-2e-5553.92% (204) abortive infection protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0827|M.bovis_AF2122/97            -----------MSRLRALSLAAGLVGWSLVS-PRLPAPWRIPLQAGLGSV
Rv0804|M.tuberculosis_H37Rv         -----------MSRLRALSLAAGLVGWSLVS-PRLPAPWRIPLQAGLGSV
MMAR_4887|M.marinum_M               -----------------------MVGWSLAS-PRLPARWRVALQAVLGGL
MUL_0411|M.ulcerans_Agy99           -----------------------MVSWSLAS-PRLPARWRVALQAVLGGL
MAV_0745|M.avium_104                ------MRPSRFRRTAALSLAGALVGWSFVG-PRLPAGARMVLQAGMGAA
MSMEG_5821|M.smegmatis_MC2_155      ------MAPMTAAKFRALALAAALTAWNVVVDPRLPERCRPVVRALVGTA
Mflv_1632|M.gilvum_PYR-GCK          ----------MRDTVRAVGLAAALLGWSATA-PRLPQEWNPLPHMVFSGA
Mvan_5117|M.vanbaalenii_PYR-1       ----------MRDGVRATALAMLLLGWSLAA-PRLPQRWNPLPQTMFGAG
MAB_0709|M.abscessus_ATCC_1997      -----------MSGARVLVLAVVLVAWPAVL-ERFPQRWRPLIGAGTSTA
TH_1367|M.thermoresistible__bu      VVAQLAALSRFRTYVDVAVVVVVLAICNLIAHFTTPWASVATVPAVAVGL
                                                           :           *              

Mb0827|M.bovis_AF2122/97            LVLVTRATMG-----LWPPRLWAGLRLGWAAGAAAATAIAATTPVPMVRL
Rv0804|M.tuberculosis_H37Rv         LVLVTRATMG-----LWPPRLWAGLRLGWAAGAAAATAIAATTPVPMVRL
MMAR_4887|M.marinum_M               LVLVTRAPLG-----LTPPRLWAGLRLGAVAAAPVATAIAATTPVPMVRL
MUL_0411|M.ulcerans_Agy99           LVLVTRAPLG-----LTPPRLWAGLRLGAVAAAPVATATAATTPVPMVRL
MAV_0745|M.avium_104                LVALTRAPLG-----LHPPRLWAGLRCGAAVAGCAAGAVAATTLVPAVRE
MSMEG_5821|M.smegmatis_MC2_155      LLGLSRAAPGSRRSGLRPPALWSGMRTGSVAAAVVASSVVATTALPAVRT
Mflv_1632|M.gilvum_PYR-GCK          VTLLSRPSLG-----LRPAQLRRGVRWGSAAAAPVGLGVAAGLMAPAVRA
Mvan_5117|M.vanbaalenii_PYR-1       VAALAGAPLG-----LRPPMLWRGLQWGSAAVAPVALSVAAATTSPPVRA
MAB_0709|M.abscessus_ATCC_1997      LAGAAGIPLG-----LRPPQLGAGLRLGGIVASAVAAAVGASPALQPVRA
TH_1367|M.thermoresistible__bu      VLLVRSRGLGWAELGLSREHWRSGAGYAAAAVALVLSVIAIGALLPWTRP
                                    :        *     *       *   .  . . .            .* 

Mb0827|M.bovis_AF2122/97            SMSARELPASVPVWLV--WHIPGGTVWAEEAAFRGALATIGARAFGRSGG
Rv0804|M.tuberculosis_H37Rv         SMSARELPASVPVWLV--WHIPGGTVWAEEAAFRGALATIGARAFGRSGG
MMAR_4887|M.marinum_M               SMSERDLPASVPGWLG--LQIPFGTVWAEEAAFRAALATMGTRGFGHVGG
MUL_0411|M.ulcerans_Agy99           SMSERDLPASVPGWLG--LQIPFGTVWAEEAAFRAALATMGTRGFGHVGG
MAV_0745|M.avium_104                SMAGREPPAPAPDWLL--LRIPVGTVWSEEAAFRAALTAAGSAAFGRRSA
MSMEG_5821|M.smegmatis_MC2_155      AMRERELPPAVAFWLM--LGIPLGTVWSEEAAFRGALGAVGTGAFGHTGG
Mflv_1632|M.gilvum_PYR-GCK          GMAARDLPAAPARWLL--LRIPFATVGPEELAYRAVLGDAATRAFGPRVG
Mvan_5117|M.vanbaalenii_PYR-1       GMVARDLPDPAASWLL--LRIPFGTVWSEEATFRAALGATAERAFGRTAG
MAB_0709|M.abscessus_ATCC_1997      SMRARDIDLHPAVWLG--LHIPVGTVWSEELAFRGVLQPLATEAFGRTAG
TH_1367|M.thermoresistible__bu      MFLNNNYATISGALIASMVIIPLQTVIPEELAFRGVLHGALSRAWGFRGV
                                     :  .:        :     **  ** .** ::*..*      .:*    

Mb0827|M.bovis_AF2122/97            RILQAGAFGLSHIADARATGEP------------------LVLTVLATGI
Rv0804|M.tuberculosis_H37Rv         RILQAGAFGLSHIADARATGEP------------------LVLTVLATGI
MMAR_4887|M.marinum_M               RLLQAATFGLSHVADARATGAP------------------PVPTVLVTGL
MUL_0411|M.ulcerans_Agy99           QLLQAVTFGLSHVADARATGAP------------------PVPTVLVTGL
MAV_0745|M.avium_104                MLLQAIAFGLSHIADARAIGEP------------------VAGTVAVTAV
MSMEG_5821|M.smegmatis_MC2_155      RLLQATAFGLSHIPDARAAGEP------------------VVGTVLATGA
Mflv_1632|M.gilvum_PYR-GCK          KLFTAVVFGLSHVPDARAAGDN------------------VPGTVVVTGA
Mvan_5117|M.vanbaalenii_PYR-1       RLFAATVFGLSHVPDARAAREP------------------ILGTVLVTGT
MAB_0709|M.abscessus_ATCC_1997      SAVQAMVFGLAHIRPARAAGDS------------------IPGTVLVTGM
TH_1367|M.thermoresistible__bu      AAAGSLLFGLWHVATSLGLTSSNVGFTRLFGGGVLGTVAGVVLAVIATAV
                                        :  *** *:  : .                         :* .*. 

Mb0827|M.bovis_AF2122/97            AGWMFGWLADRSGSLAAPLLTHLAINEAGAVAAVLVQRR----SGISTRL
Rv0804|M.tuberculosis_H37Rv         AGWMFGWLADRSGSLAAPLLTHLAINEAGAVAAVLVQRR----SGISTRL
MMAR_4887|M.marinum_M               AGWLFGWLAERSGSLAAPMVLHLAINEAGAVAALTVQRRWINGAEITPRR
MUL_0411|M.ulcerans_Agy99           AGWLFGWLAERSGSLAAPMVLHLAINEAGAVAALTVQRRWINGAEITPRR
MAV_0745|M.avium_104                GGWFFGWLTDRCGSLAAPMLAHLAVNEAGAIAVLAVRRR--SGRNAAPRI
MSMEG_5821|M.smegmatis_MC2_155      AGWFLDWLMHRTKSLAAPLLVHLALNEAGALAAVWYARK-------SPRP
Mflv_1632|M.gilvum_PYR-GCK          AGWVFSWLHESSGSLAAPVLAHLAVNEAGAVAALAVQQRRSGRGRPTGAA
Mvan_5117|M.vanbaalenii_PYR-1       AGWAFSWLYAKSGSLVAPMLAHLAVNEAGAVAALAVQRRRSARGRPADGA
MAB_0709|M.abscessus_ATCC_1997      FGWLLGRLRERSGSVVAPMLAHLALNEAGAVATLYLGRSNVDLSPESASN
TH_1367|M.thermoresistible__bu      AGFVFDWLRRRSGSLLAPIALHWSLNGMGALAAALVWHLST---------
                                     *: :. *     *: **:  * ::*  **:*.    :            

Mb0827|M.bovis_AF2122/97            ---------
Rv0804|M.tuberculosis_H37Rv         ---------
MMAR_4887|M.marinum_M               RYT------
MUL_0411|M.ulcerans_Agy99           RYT------
MAV_0745|M.avium_104                ---------
MSMEG_5821|M.smegmatis_MC2_155      Q--------
Mflv_1632|M.gilvum_PYR-GCK          R--------
Mvan_5117|M.vanbaalenii_PYR-1       RSPGRRSRS
MAB_0709|M.abscessus_ATCC_1997      ---------
TH_1367|M.thermoresistible__bu      ---------