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ASTTGKKLAAVLGTGQTKYVAKRKDVSMNGLVREAIDRALDDAGVTLADIDAVVVGKAPDFFEGVMMPEL FMADATGATGKPLIRVHTAGSVGGSTAIVAASLVQSGKYRRVLTMAWEKQSESNAMWALSIPVPFTKPVG AGAGGYFAPHVRAYIRRSGAPTYIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVMESPMLWDPIRYDETC PSSDGAAALVIGDEASADARVAEGHPVAWIHATALRTEPLAYAGRDQVNPQASRDAAAALWKSAGISSPI DEIDVAEVYVPFSWYEPMWLESLGFAPEGEGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFAE SAIQVMNKAGEHQVPNARKALGHAYGGGAQYFSMWVVGSDKPGDKPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1536 | - | - | 100% (398) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_2505 | - | 2e-35 | 32.45% (379) | thiolase |
| M. gilvum PYR-GCK | Mflv_2025 | - | 5e-26 | 25.96% (389) | lipid-transfer protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3553 | - | 0.0 | 87.31% (386) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv3523 | ltp3 | 0.0 | 87.31% (386) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4169 | - | 0.0 | 84.62% (390) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_5008 | ltp3 | 0.0 | 87.56% (386) | lipid carrier protein or keto acyl-CoA thiolase Ltp3 |
| M. avium 104 | MAV_0636 | - | 0.0 | 88.14% (388) | acetyl-CoA acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5923 | - | 0.0 | 91.75% (388) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0379 | - | 1e-115 | 85.27% (224) | PROBABLE LIPID CARRIER PROTEIN OR KETO ACYL-COA THIOLASE LTP3 |
| M. ulcerans Agy99 | MUL_4082 | ltp3 | 0.0 | 86.79% (386) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5222 | - | 0.0 | 97.67% (387) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1536|M.gilvum_PYR-GCK MASTTGKKLAAVLGTGQTKYVAKRKDVSMNGLVREAIDRALDDAGVTLAD
Mvan_5222|M.vanbaalenii_PYR-1 MAS---KKLAAVLGTGQTKYVAKRKDVSMNGLVREAIDRALEDAGVTLAD
MSMEG_5923|M.smegmatis_MC2_155 MAVN-----AAVLGTGQTKYVAKRTDVSMNGLVREAIDRALADSGSTMAD
Mb3553|M.bovis_AF2122/97 MAG----KLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDD
Rv3523|M.tuberculosis_H37Rv MAG----KLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDD
MMAR_5008|M.marinum_M MAGA-RAQLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALQDSGSTFDD
MUL_4082|M.ulcerans_Agy99 MAGA-RAQLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALQDSGSTFDD
MAV_0636|M.avium_104 MAGA-GPNIAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGCTFDD
MAB_4169|M.abscessus_ATCC_1997 -MGA-SKNLAAVIGTGQTKYVAKRQDVSMNGLVREAIDRAMTDAGVDWDD
TH_0379|M.thermoresistible__bu --------------------------------------------------
Mflv_1536|M.gilvum_PYR-GCK IDAVVVGKAPDFFEGVMMPELFMADATGATGKPLIRVHTAGSVGGSTAIV
Mvan_5222|M.vanbaalenii_PYR-1 IDAVVVGKAPDFFEGVMMPELFMADATGATGKPLIRVHTAGSVGGSTAIV
MSMEG_5923|M.smegmatis_MC2_155 IDAVVVGKAPDFFEGVMMPELFMADAVGATGKPLIRVHTAGSVGGSTAIV
Mb3553|M.bovis_AF2122/97 IDAVVVGKAPDFFEGVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVV
Rv3523|M.tuberculosis_H37Rv IDAVVVGKAPDFFEGVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVV
MMAR_5008|M.marinum_M IDAVVVGKAPDFFEGVMMPELFMADAMGASGKPLIRVHTAGSVGGSTGVV
MUL_4082|M.ulcerans_Agy99 IDAVVVGKAPDFFEGVMMPELFMADAMGASGKPLIRVHTAGSVGGSTGVV
MAV_0636|M.avium_104 IDAVVVGKAPDFFEGVMMPELFMADAVGATGKPLIRVHTAGSVGGSTGVV
MAB_4169|M.abscessus_ATCC_1997 IDAVVVGKAPDFFEGVMMPELFMADAIGATGKPMIRVHTAGSVGGSTGVV
TH_0379|M.thermoresistible__bu --------------------------------------------------
Mflv_1536|M.gilvum_PYR-GCK AASLVQSGKYRRVLTMAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
Mvan_5222|M.vanbaalenii_PYR-1 AASLVQSGKYRRVLTMAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
MSMEG_5923|M.smegmatis_MC2_155 AASLVKSGRYRRVLTMAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
Mb3553|M.bovis_AF2122/97 AASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
Rv3523|M.tuberculosis_H37Rv AASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAP
MMAR_5008|M.marinum_M AASLVQSGKYRRVLAMAWEKQSESNAMWALSIPIPFIKPVGAGAGGYFAP
MUL_4082|M.ulcerans_Agy99 AASLVQSGKYRRVLAMAWEKQSESNAMWALSIPIPFIKPVGAGAGGYFAP
MAV_0636|M.avium_104 AASLVQSGKYRRVLAMAWEKQSESNAMWALSIPVPFIKPVGAGAGGYFAP
MAB_4169|M.abscessus_ATCC_1997 AASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFSVPVGAGAGGYFAP
TH_0379|M.thermoresistible__bu ---------------MSRESRSSAETRFRLLFFEVCHXXX----------
:: *.:*.::: : * :
Mflv_1536|M.gilvum_PYR-GCK HVRAYIRRSGAPTYIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVMESPM
Mvan_5222|M.vanbaalenii_PYR-1 HVRAYIRRSGAPTHIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVMESPM
MSMEG_5923|M.smegmatis_MC2_155 HVRAYIRRSGAPTHIGAMVAVKDRLNGAKNPLAHLHQPDITLEKVLSSQM
Mb3553|M.bovis_AF2122/97 HVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQM
Rv3523|M.tuberculosis_H37Rv HVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQM
MMAR_5008|M.marinum_M HVRAYIRRSGAPSNIGAMVAVKDRLNGSRNPLAHLQQPDITLDKVMQSPM
MUL_4082|M.ulcerans_Agy99 HVRAYIRRSGAPSNIGAMVAVKDRLNGSRNPLAHLQQPDITLDEVMQSPM
MAV_0636|M.avium_104 HVRAYIRRSGAPTHIGAMVAVKDRLNGCRNPLAHLHQPDITLEKVMESPM
MAB_4169|M.abscessus_ATCC_1997 HVRAYIQRSKAPLDTGAMVAVKDRLNAAKNPLAHLHQPDITVEKVMSSPM
TH_0379|M.thermoresistible__bu -------------------AVKDRLNGARNPLAHLQQPDITLEKVLDSQM
*******..:******:*****:::*: * *
Mflv_1536|M.gilvum_PYR-GCK LWDPIRYDETCPSSDGAAALVIGDEASADARVAEGHPVAWIHATALRTEP
Mvan_5222|M.vanbaalenii_PYR-1 LWDPIRYDETCPSSDGAAAMVIGDEASADARVAEGHPVAWIHATALRTEP
MSMEG_5923|M.smegmatis_MC2_155 LWDPIRFDETCPSSDGACAMVIGDDHIADARVAEGHPVAWIHATALRTEP
Mb3553|M.bovis_AF2122/97 LWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGTALRTEP
Rv3523|M.tuberculosis_H37Rv LWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGTALRTEP
MMAR_5008|M.marinum_M LWDPIRYDETCPSSDGACAVVIGNEEIADTRVADGHPVAWIHATALRTEP
MUL_4082|M.ulcerans_Agy99 LWDPIRYDETCPSSDGACAVVVGNEEIADARVADGHPVAWIHATALRTEP
MAV_0636|M.avium_104 LWDPIRYDETCPSSDGACAVVIGNEEAAEARLAQGNPVAWIHATALRTEP
MAB_4169|M.abscessus_ATCC_1997 LWDPIRFDETCPSSDGACAIVVGDEQTADRRIKEGHAVAWVHATALRTEP
TH_0379|M.thermoresistible__bu LWDPIRFDETCPSSDGACAVVIGDEATADARVADGHPVAWIHATALRTEP
******:**********.*:*:*:: *: *: :*:.***:*.*******
Mflv_1536|M.gilvum_PYR-GCK LAYAGRDQVNPQASRDAAAALWKSAGISSPIDEIDVAEVYVPFSWYEPMW
Mvan_5222|M.vanbaalenii_PYR-1 LAYAGRDQVNPQASRDAAAALWKSAGITSPIDEIDVAEVYVPFSWYEPMW
MSMEG_5923|M.smegmatis_MC2_155 LAYAGRDQVNPQAGRDAAKALWRDAGITSPIDEIDVAEVYVPFSWFEPMW
Mb3553|M.bovis_AF2122/97 LAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
Rv3523|M.tuberculosis_H37Rv LAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
MMAR_5008|M.marinum_M LAYSGRDQVSPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
MUL_4082|M.ulcerans_Agy99 LAYSGRDQVSPQAGRDTAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMW
MAV_0636|M.avium_104 LAYAGRDQVSPQAGRDAAAALWKAAGIKSPIDEIDAAEIYVPFSWFEPMW
MAB_4169|M.abscessus_ATCC_1997 LDYTGRDRVNPQAGRDAAAALWKDAGITSPIDEIDVAEIYVPFSWFEPMW
TH_0379|M.thermoresistible__bu LAYAGRDQVNPQAGRDAAKALWEAAGITNPLEEIDVAEIYVPFSWFEPMW
* ::***:*.***.**:* ***. ***..*::***.**:******:****
Mflv_1536|M.gilvum_PYR-GCK LESLGFAPEGEGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFA
Mvan_5222|M.vanbaalenii_PYR-1 LESLGFAPEGGGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFA
MSMEG_5923|M.smegmatis_MC2_155 LENLGFAPEGEGWKLTEAGETAIGGRIPFNPSGGVLSSNPIGASGMIRFA
Mb3553|M.bovis_AF2122/97 LENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFA
Rv3523|M.tuberculosis_H37Rv LENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFA
MMAR_5008|M.marinum_M LENLGFMPEGEGWKLTEAGETAIGGRLPVNPSGGVLSSNPIGASGLIRFA
MUL_4082|M.ulcerans_Agy99 LENLGFMPEGEGWKLTEAGETAIGGRLPVNPSGGVLSSNPIGASGLIRFA
MAV_0636|M.avium_104 LENLGFAPEGEGWKLTEAGETKIGGRLPVNPSGGVLSSNPIGASGLIRFA
MAB_4169|M.abscessus_ATCC_1997 LENLGFAAEGEGWKLTQAGETAIGGKIPVNASGGVLSSNPIGASGLIRFA
TH_0379|M.thermoresistible__bu LENLGFAAEGEGWRLTEAGETAIGGKLPVNPSGGVLSSNPIGASGMIRFA
**.*** ** **:**:**** ***::*.*.******:*******:****
Mflv_1536|M.gilvum_PYR-GCK ESAIQVMNKAGEHQVPNARKALGHAYGGGAQYFSMWVVGSDKPGDKPA
Mvan_5222|M.vanbaalenii_PYR-1 ESAIQVMGKAGEHQVPGARKALGHAYGGGAQYFSMWVVSADKPA----
MSMEG_5923|M.smegmatis_MC2_155 ESAIQVMGKAGEHQVQGARKALGHAYGGGSQYFSMWVVSSDKPAAKP-
Mb3553|M.bovis_AF2122/97 EAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
Rv3523|M.tuberculosis_H37Rv EAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
MMAR_5008|M.marinum_M EAAIQVMGKGGDHQVPNARKALGHAYGGGSQYYSMWVVGADKP-----
MUL_4082|M.ulcerans_Agy99 EAAIQVMGKGGDHQVPNARKTLGHAYGGGSQYYSMWVVGADKP-----
MAV_0636|M.avium_104 EAAIQVMGKGGDHQVPGARKALGHAYGGGSQYYSMWVVGADKPAAEKV
MAB_4169|M.abscessus_ATCC_1997 EAAIQVMGKAGDHQVPGAKKALGHAYGGGSQYYSMWVVGSEKPAGKEQ
TH_0379|M.thermoresistible__bu EAAIQVMGKAGDHQVEGARKALGHAYGGGSQYFSMWVVGADKPVLR--
*:*****.*. :** .*:*:********:**:*****..:**