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VTETPIAPLDDTPRFRYTAVLAGEIERAWQQQWADSGTFHVDNPVGSLAPADGSAVPADKMFVQDMFPYP SGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLG RLGLGHDSRRSFATTDVDYYKWTQWIFLQIFNAWFDTDQNRARPIRELIAEFEAGTRQVGDGRSWADLDA GARADLVDAHRLVYLADSVVNWCPGLGTVLANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLLED LDVLDWPDKVKTMQRNWIGRSTGAEVQFSTAAGDIEVFTTRPDTLFGATYMVLAPEHDLVDRLVASAWPD GTDARWTFGAATPAEAVAAYRAGIAAKSDLERQENKTKTGVFLGAYATNPANGQQVPVFIADYVLAGYGT GAIMAVPSGDQRDWDFATEFGLPIVEVVAGGDVTVEAYSGDGTMVNSGFLDGMDVATAKQAMTERLVADG RGRARVEYKLRDWLFARQRYWGEPFPVVYDSEGRAHGLPEGMLPVELPDVPDYSPVSFDPDDAGSEPSPP LGKVTDWVNVDLDLGDGLKPYTRDTNVMPQWAGSSWYELRYTDPYNSEALCAKENEAYWMGPRPAEHGPD DPGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEVIE RDGKFVWPGPDGETEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASRPWATKDVVGAY RFLQRVWRLVVDENTGETLATEDALDDDTLRLLHRTIAGTADDYASLRNNTAAAKLIEYTNHLTKQSVTA RAALEPLVLMVAPLAPHLAEELWKRLGHEGSLAHGPFPLADERYLVEDTVEYPVQVNGKVRGRVTVPADA PADAVEAAALAEEKVVAFLDGRTPKKVIVVAGRLVNVVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0853 | leuS | - | 100% (949) | leucyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_1930 | - | 1e-09 | 30.00% (130) | methionyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_3644 | ileS | 2e-05 | 25.73% (171) | isoleucyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0042 | leuS | 0.0 | 78.82% (949) | leucyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv0041 | leuS | 0.0 | 78.82% (949) | leucyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_00032 | leuS | 0.0 | 76.89% (952) | leucyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_4923c | leuS | 0.0 | 77.59% (955) | leucyl-tRNA synthetase |
| M. marinum M | MMAR_0057 | leuS | 0.0 | 79.75% (948) | leucyl-tRNA synthetase LeuS |
| M. avium 104 | MAV_0055 | leuS | 0.0 | 81.22% (953) | leucyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_6917 | leuS | 0.0 | 83.95% (947) | leucyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_0509 | leuS | 0.0 | 82.53% (950) | PROBABLE LEUCYL-tRNA SYNTHETASE LEUS (LEUCINE--tRNA LIGASE) |
| M. ulcerans Agy99 | MUL_0056 | leuS | 0.0 | 79.22% (948) | leucyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_6054 | leuS | 0.0 | 88.53% (968) | leucyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0042|M.bovis_AF2122/97 -----------------------MTESPTAGPG-------GVPR-ADDAD
Rv0041|M.tuberculosis_H37Rv -----------------------MTESPTAGPG-------GVPR-ADDAD
MMAR_0057|M.marinum_M -----------------------MTESPTTTPGSTSGAPSGVPSGVNDAE
MUL_0056|M.ulcerans_Agy99 -----------------------MTESPTTTPGSTSGAPSGVPSGVNDAE
MLBr_00032|M.leprae_Br4923 -----------------------MTELPTTVPG--------YNSAVAQTD
MAV_0055|M.avium_104 MRNATETNLWPAKPPRRPLYPVQVTESPTTSPA--------TGSGAAAPD
Mflv_0853|M.gilvum_PYR-GCK -----------------------MTETPIAP------------------L
Mvan_6054|M.vanbaalenii_PYR-1 -----------------------MTETPTGTQS-----------SRETAA
MSMEG_6917|M.smegmatis_MC2_155 -----------------------MTEPATTP---------------TTPD
TH_0509|M.thermoresistible__bu -----------------------VTDSTSTD------------------T
MAB_4923c|M.abscessus_ATCC_199 -----------------------MTETQHDATD----------------T
:*:
Mb0042|M.bovis_AF2122/97 SDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDD
Rv0041|M.tuberculosis_H37Rv SDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDD
MMAR_0057|M.marinum_M SDAPRHRYTAELAAGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPED
MUL_0056|M.ulcerans_Agy99 SDAPRHRYTAELAAGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPED
MLBr_00032|M.leprae_Br4923 SDAMRYRYTAELAGRIESTWQDNWARLQTFNVPNPVGSLAPPDGSVVPAD
MAV_0055|M.avium_104 SDAPPYRYTAALAGRIEGSWQDTWAKLGTFNVPNPVGSLAPTDGTPVPED
Mflv_0853|M.gilvum_PYR-GCK DDTPRFRYTAVLAGEIERAWQQQWADSGTFHVDNPVGSLAPADGSAVPAD
Mvan_6054|M.vanbaalenii_PYR-1 DDTPRHRYTAGLAGEIERAWQQRWTQDGTFDVANPVGSLAPADGSAVPAD
MSMEG_6917|M.smegmatis_MC2_155 EQIPRHRYNADLAGQIERAWQETWSDRGTFNVANPVGSLAPTDGSDVPAD
TH_0509|M.thermoresistible__bu TDTPPFRYTAKLAGEIERRWQQTWAEQGTFHVPNPVGSLAPPDGSPVPAD
MAB_4923c|M.abscessus_ATCC_199 AELPRHRYTAQLAGQIERRWQQTWADRGTFHVPNPVGSLAPTDGTPIPAD
: .**.* **. :* **: *: **.* ********.**: :* *
Mb0042|M.bovis_AF2122/97 KLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAF
Rv0041|M.tuberculosis_H37Rv KLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAF
MMAR_0057|M.marinum_M KLFVQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGRNVLHALGFDAF
MUL_0056|M.ulcerans_Agy99 KLFVQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGRNVLHALGFDAF
MLBr_00032|M.leprae_Br4923 KLFVQDMFPYPSGDGLHVGHPLGYIATDVYARYFRMTGHNVLHAMGFDAF
MAV_0055|M.avium_104 KLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMTGRNVLHALGFDAF
Mflv_0853|M.gilvum_PYR-GCK KMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAF
Mvan_6054|M.vanbaalenii_PYR-1 KMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAF
MSMEG_6917|M.smegmatis_MC2_155 KMFVQDMFPYPSGDGLHVGHPLGYIATDVYARYYRMLGRNVLHALGFDAF
TH_0509|M.thermoresistible__bu KMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYHRMRGRNVLHALGFDAF
MAB_4923c|M.abscessus_ATCC_199 KMFVQDMFPYPSGDGLHVGHPLGYIATDVYARFHRMRGANVLHALGFDAF
*:***********:***************:**:.** * *****:*****
Mb0042|M.bovis_AF2122/97 GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDF
Rv0041|M.tuberculosis_H37Rv GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDF
MMAR_0057|M.marinum_M GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEF
MUL_0056|M.ulcerans_Agy99 GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEF
MLBr_00032|M.leprae_Br4923 GLPAEQYAMQTGTHPRILTEANVVNFRHQLGRLGLGHDSRRTFSTTDVEF
MAV_0055|M.avium_104 GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEF
Mflv_0853|M.gilvum_PYR-GCK GLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFATTDVDY
Mvan_6054|M.vanbaalenii_PYR-1 GLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFSTTDVDF
MSMEG_6917|M.smegmatis_MC2_155 GLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLGHDTRRSFSTTDVDY
TH_0509|M.thermoresistible__bu GLPAEQYAVQTGTHPRTRTEANIANFRRQLGRLGLGHDDRRSFSTTDVEY
MAB_4923c|M.abscessus_ATCC_199 GLPAEQYAVQTGTHPRVRTEANIVNYKRQLGRLGLGHDSRRSFATTDVDF
********:******* ****:.*:::******:*** **:*:****::
Mb0042|M.bovis_AF2122/97 YRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLT
Rv0041|M.tuberculosis_H37Rv YRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLT
MMAR_0057|M.marinum_M YKWTQWIFLQIYNAWFDAAANKARPISELVAEFDSGARSLVDGRDWSTLS
MUL_0056|M.ulcerans_Agy99 YKWTQWIFLQIYNAWFDAAANKARPISELVAEFDSGARSLVDGRDWSTLS
MLBr_00032|M.leprae_Br4923 YKWTQWIFLQIYNAWFDVAANKARPIAELIAEFDSGERRLVDGRDWATLS
MAV_0055|M.avium_104 YKWTQWIFLQIYNAWFDPAANKARPIAELVAEFDSGARSLDDGRNWSELS
Mflv_0853|M.gilvum_PYR-GCK YKWTQWIFLQIFNAWFDTDQNRARPIRELIAEFEAGTRQVGDGRSWADLD
Mvan_6054|M.vanbaalenii_PYR-1 YKWTQWIFLQIYNAWFDTAQNKARPVAELIAEFEAGTREVGDGRRWADLD
MSMEG_6917|M.smegmatis_MC2_155 YKWTQWIFLQIYNAWFDRDQNKARRISELVEEFESGKRTLDDGRNWADLS
TH_0509|M.thermoresistible__bu YKWTQWIFLQIFNAWFDPDQNKARPISELVAEFESGARPVGDGRSWSELP
MAB_4923c|M.abscessus_ATCC_199 YKWTQWIFLQIYNAWYDEQARRARPIQELIAEFDSGTRAPSDGTVWAELS
*:*********:***:* .:** : **: **::* * .* *: *
Mb0042|M.bovis_AF2122/97 AGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVF
Rv0041|M.tuberculosis_H37Rv AGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVF
MMAR_0057|M.marinum_M AGERADVIDDHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVF
MUL_0056|M.ulcerans_Agy99 AGERADVIDDHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVF
MLBr_00032|M.leprae_Br4923 AGERADVIDNCRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVF
MAV_0055|M.avium_104 AGERADVIDSHRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVF
Mflv_0853|M.gilvum_PYR-GCK AGARADLVDAHRLVYLADSVVNWCPGLGTVLANEEVTADGRSERGNFPVF
Mvan_6054|M.vanbaalenii_PYR-1 AGERADVVDSRRLVYLADSVVNWCPGLGTVLANEEVTSDGRSERGNFPVF
MSMEG_6917|M.smegmatis_MC2_155 KGERADVIDGYRLVYRADSMVNWCPGLGTVLANEEVTSEGRSDRGNFPVF
TH_0509|M.thermoresistible__bu AGERHDIIDSYRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVF
MAB_4923c|M.abscessus_ATCC_199 VGARADVIDSYRLVYQSDSVVNWCPGLGTVLANEEVTADGRSERGNFPVF
* * *::* **** :**:*****************::***:*******
Mb0042|M.bovis_AF2122/97 RKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFS
Rv0041|M.tuberculosis_H37Rv RKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFS
MMAR_0057|M.marinum_M RKRLRQWMMRITAYSDRLLDDLDVLDWPDQVKTMQRNWIGRSTGASALFT
MUL_0056|M.ulcerans_Agy99 RKRLRQWMMRITAYSDRLLDDLDVLDWPDQVKTMQRNWIGRSTGASALFT
MLBr_00032|M.leprae_Br4923 RKRLRQWMMRITAYADRLLDDLDLLDWPEQVKTMQRNWIGRSSGATVLFS
MAV_0055|M.avium_104 RKRLRQWMMRITAYSDRLLDDLDLLDWPEPVKTMQRNWIGRSTGAKALFA
Mflv_0853|M.gilvum_PYR-GCK RKRLRQWMMRITAYSDRLLEDLDVLDWPDKVKTMQRNWIGRSTGAEVQFS
Mvan_6054|M.vanbaalenii_PYR-1 RKRLRQWMMRITAYSDRLLEDLDVLDWPDKVKTMQRNWIGRSTGASVEFG
MSMEG_6917|M.smegmatis_MC2_155 RKRLRQWMMRITAYSDRLLEDLDVLDWPEKVKTMQRNWIGRSTGASVLFA
TH_0509|M.thermoresistible__bu RKRLRQWMMRITAYAERLLEDLDVLDWPEKVKTMQRNWIGRSTGAAVLFA
MAB_4923c|M.abscessus_ATCC_199 RKRLRQWMMRITAYSDRLIDDLDVLDWPDKVKTMQRNWIGRSQGASVLFG
**************::**::***:****: ************ ** . *
Mb0042|M.bovis_AF2122/97 ARAASD--DGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPA
Rv0041|M.tuberculosis_H37Rv ARAASD--DGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPA
MMAR_0057|M.marinum_M ATRS----NGETVGLEVFTTRPDTLFGATYLVLAPEHDLVDDLVGAGWPA
MUL_0056|M.ulcerans_Agy99 ATRS----NGETVGLEVFTTRPDTLFGATYLVLAPEHDLVDDLVGAGWPA
MLBr_00032|M.leprae_Br4923 AILSRSDAATTEVDVEVFTTRPDTMFGVTYLVLAPEHNLVDELVATVWPD
MAV_0055|M.avium_104 ATGA----DGAALDIEVFTTRPDTLFGATYMVLAPEHELVDELVAPAWPD
Mflv_0853|M.gilvum_PYR-GCK TAAG---------DIEVFTTRPDTLFGATYMVLAPEHDLVDRLVASAWPD
Mvan_6054|M.vanbaalenii_PYR-1 TDAG---------DIEVFTTRPDTLFGATYMVLAPEHDLVDRLVADQWPA
MSMEG_6917|M.smegmatis_MC2_155 TAAD---------DIEVFTTRPDTLFGATYLVLAPEHDLVDTLVTDAWPD
TH_0509|M.thermoresistible__bu TDAG---------DIEVFTTRPDTLFGATYMVLAPEHDMVDQLVADRWPD
MAB_4923c|M.abscessus_ATCC_199 APGAG--------DIEVFTTRPDTLFGATYMVLAPEHPLVDQLAADVWPQ
: .:*********:**.**:****** :** *. **
Mb0042|M.bovis_AF2122/97 GVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINP
Rv0041|M.tuberculosis_H37Rv GVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINP
MMAR_0057|M.marinum_M GVDPLWTGGGATPAEAVAAYRRAIAAKSDLERQESKEKTGVFLGSHAINP
MUL_0056|M.ulcerans_Agy99 GVDPLWTGGGATPAEAVAAYRRAIAVKSDLERQESKEKTGVFLGSHAINP
MLBr_00032|M.leprae_Br4923 RTDPRWTYGAATPGAAVAAYRRAIVAKSDLDRQESKEKTGVFLGRYATNP
MAV_0055|M.avium_104 GTDPRWTYGAATPGEAVAAYRRAIASKSDLERQESKAKTGVFLGSYATNP
Mflv_0853|M.gilvum_PYR-GCK GTDARWTFGAATPAEAVAAYRAGIAAKSDLERQENKTKTGVFLGAYATNP
Mvan_6054|M.vanbaalenii_PYR-1 DVDARWTFGAATPREAVAAYRASIAAKSDLERQENKAKTGVFIGAYATNP
MSMEG_6917|M.smegmatis_MC2_155 GTDERWTYGAATPREAVAAYRTDIAAKSDLERQENKTKTGVFLGAYATNP
TH_0509|M.thermoresistible__bu GVDPRWTLGAGTPKEAVSTYRAAIAAKSDLERQENKDKTGVFLGAYATNP
MAB_4923c|M.abscessus_ATCC_199 DTDPRWTGGQDSPRAAIEQYRRSIAAKSDLERQENKEKTGVFTGAYATNP
.: ** * :* *: ** *. ****:***.: ***** * :* **
Mb0042|M.bovis_AF2122/97 ANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVI--
Rv0041|M.tuberculosis_H37Rv ANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVI--
MMAR_0057|M.marinum_M ATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVI--
MUL_0056|M.ulcerans_Agy99 ATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVI--
MLBr_00032|M.leprae_Br4923 ATGKPVPIFVADYVLVGYGTGAVMAVPGHDPRDWDFAHKFHLPIVEVI--
MAV_0055|M.avium_104 TNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVI--
Mflv_0853|M.gilvum_PYR-GCK ANGQQVPVFIADYVLAGYGTGAIMAVPSGDQRDWDFATEFGLPIVEVV--
Mvan_6054|M.vanbaalenii_PYR-1 ANAKQVPVFIADYVLAGYGTGAIMAVPGGDQRDWDFATEFGLPIIEVVRP
MSMEG_6917|M.smegmatis_MC2_155 ADGKQVPIFIADYVLAGYGTGAIMAVPGGDQRDWDFAKEFGLPIIEVV--
TH_0509|M.thermoresistible__bu ANGERIPVFIADYVLLGYGTGAIMAVPGHDQRDWEFAREFGLPIVEVI--
MAB_4923c|M.abscessus_ATCC_199 VSGKPVPVFIADYVLLGYGTGAIMAVPGHDQRDWDFANTFGLPVQEVI--
. .: :*:*:***** ******:****. * ***:** : **: **:
Mb0042|M.bovis_AF2122/97 ----------AGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLES
Rv0041|M.tuberculosis_H37Rv ----------AGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLES
MMAR_0057|M.marinum_M ----------AGGDISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLES
MUL_0056|M.ulcerans_Agy99 ----------AGGDISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLES
MLBr_00032|M.leprae_Br4923 ----------AGSDISEAAYVGDGVLVNSGYLDGMDVATAQEAITARLES
MAV_0055|M.avium_104 ----------AGGDISEGAYAGDGLLVNSGYLDGLDVAAAKEAITARLEA
Mflv_0853|M.gilvum_PYR-GCK ----------AGGDVTVEAYSGDGTMVNSGFLDGMDVATAKQAMTERLVA
Mvan_6054|M.vanbaalenii_PYR-1 VADRPGEDTGAGGDVSQAAYTGDGVMVNSGFLDGMDVSAAKEAMTERLSA
MSMEG_6917|M.smegmatis_MC2_155 ----------TGGDISEAAYAGDGTMVNSGFLDGMDVASAKEAIIARLEA
TH_0509|M.thermoresistible__bu ----------AGGNISEAAHTGDGELVNSGFLNGMNVEDAKDAMTSRLAA
MAB_4923c|M.abscessus_ATCC_199 ----------SGGDVTKAAYTGDGVLVNSDYLDGLDIEAAKVEVTRRLVK
:*.::: *: *** :***.:*:*:.: *: : **
Mb0042|M.bovis_AF2122/97 AGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELP
Rv0041|M.tuberculosis_H37Rv AGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELP
MMAR_0057|M.marinum_M DGHGQARIEFKLRDWLFARQRYWGEPFPIVYDADGRPHALDESALPVELP
MUL_0056|M.ulcerans_Agy99 DGYGQARIEFKLRDWLFARQRYWGEPFPIVYDADGRPHALDESALPVELP
MLBr_00032|M.leprae_Br4923 EGRGHARIEFKLRDWLFARQRYWGEPFPIIYDSDGRPHALDEAALPVELP
MAV_0055|M.avium_104 EGRGCARVEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELP
Mflv_0853|M.gilvum_PYR-GCK DGRGRARVEYKLRDWLFARQRYWGEPFPVVYDSEGRAHGLPEGMLPVELP
Mvan_6054|M.vanbaalenii_PYR-1 DGRGRERVEYKLRDWLFARQRYWGEPFPIVYDADDRAHGLPEELLPVELP
MSMEG_6917|M.smegmatis_MC2_155 DGRGKRRVEYKLRDWLFARQRYWGEPFPIVYDADGRAHPLPESALPVELP
TH_0509|M.thermoresistible__bu EGRGEARVEYKLRDWLFARQRYWGEPFPIVYDSDGRPHPLPESMLPVELP
MAB_4923c|M.abscessus_ATCC_199 DGRGESRIEYKLRDWLFARQRYWGEPFPIVYDEDGRPRALGENVLPVELP
* * *:*:******************::** :.*.: * * ******
Mb0042|M.bovis_AF2122/97 DVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVM
Rv0041|M.tuberculosis_H37Rv DVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVM
MMAR_0057|M.marinum_M DVPDYSPVLFDPDDANSEPSPPLGKATEWVHVELDLGDGLKPYSRDTNVM
MUL_0056|M.ulcerans_Agy99 DVPDYSPVLFDPDDANSEPSPPLGKATEWLHVELDLGDGLKPYSRDTNVM
MLBr_00032|M.leprae_Br4923 DVPYYSPVLFDPDDADSEPSPPLAKATEWVHVELDLGDGLKPYSRDTNVM
MAV_0055|M.avium_104 DVPDYSPVLFDPDDADSEPSPPLAKATDWVHVELDLGDGLKPYSRDTNVM
Mflv_0853|M.gilvum_PYR-GCK DVPDYSPVSFDPDDAGSEPSPPLGKVTDWVNVDLDLGDGLKPYTRDTNVM
Mvan_6054|M.vanbaalenii_PYR-1 DVPDYSPVLFDPDDADSEPSPPLAKATEWVNVELDLGDGRKRYTRDTNVM
MSMEG_6917|M.smegmatis_MC2_155 DVPDYSPVLFDPDDADSEPSPPLNKATEWVHVELDLGDGLQSYTRDTNVM
TH_0509|M.thermoresistible__bu DIPDYAPVSFDPDDADSEPSPPLNKATDWVTVELDLGNGLKTYTRDTNVM
MAB_4923c|M.abscessus_ATCC_199 EVEDYAPVSFDPDDASSEPSPPLSKAADWVNVELDLGDGLKHYTRDTNVM
:: *:** ******.******* *.::*: *:****:* : *:******
Mb0042|M.bovis_AF2122/97 PQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLY
Rv0041|M.tuberculosis_H37Rv PQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLY
MMAR_0057|M.marinum_M PQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDPGGVDLY
MUL_0056|M.ulcerans_Agy99 PQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDPGGVDLY
MLBr_00032|M.leprae_Br4923 PQWAGSSWYELRYTDPHNSERLCAKENEAYWMGPRPTEHGIDDPGGVDLY
MAV_0055|M.avium_104 PQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGVDLY
Mflv_0853|M.gilvum_PYR-GCK PQWAGSSWYELRYTDPYNSEALCAKENEAYWMGPRPAEHGPDDPGGVDLY
Mvan_6054|M.vanbaalenii_PYR-1 PQWAGSSWYELRYADPHNTEALCAKENEAYWMGPRPAEHGPDDPGGVDLY
MSMEG_6917|M.smegmatis_MC2_155 PQWAGSSWYELRYTDPHNPDEMCAKENEAYWMGPRPDEHGPEDPGGVDLY
TH_0509|M.thermoresistible__bu PQWAGSSWYELRYCDPHNSEEMCAKENEAYWMGPRPEIHGPDDPGGVDLY
MAB_4923c|M.abscessus_ATCC_199 PQWAGSSWYELRYADPDNAEAFCDKENEAYWLGPRPAEHGPNDPGGVDLY
************* ** *.: :* ****:**:**** ** :********
Mb0042|M.bovis_AF2122/97 VGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDA
Rv0041|M.tuberculosis_H37Rv VGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDA
MMAR_0057|M.marinum_M VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDA
MUL_0056|M.ulcerans_Agy99 VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDA
MLBr_00032|M.leprae_Br4923 VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLINQGYIQAFAYTDA
MAV_0055|M.avium_104 VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDS
Mflv_0853|M.gilvum_PYR-GCK VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDS
Mvan_6054|M.vanbaalenii_PYR-1 VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDA
MSMEG_6917|M.smegmatis_MC2_155 VGGVEHAVLHLLYSRFWHKVLYDLGYVSSREPYRRLVNQGYIQAFAYTDS
TH_0509|M.thermoresistible__bu VGGVEHAVLHLLYARFWHKVLYDLGHVTSREPYRRLVNQGYIQAYAYTDP
MAB_4923c|M.abscessus_ATCC_199 VGGMEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLLNQGYIQAHAYTDA
*** *********:***********:*:******:*:*******.****.
Mb0042|M.bovis_AF2122/97 RGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICD
Rv0041|M.tuberculosis_H37Rv RGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICD
MMAR_0057|M.marinum_M RGSYVPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICD
MUL_0056|M.ulcerans_Agy99 RGSYVPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICD
MLBr_00032|M.leprae_Br4923 HGSYVPANQVFQRGDGFFCPGPDGEIEVFQEFGKIGKSLKNSVSPDEICD
MAV_0055|M.avium_104 RGSYVPAEEVVERDGRFFYRGPDGEIEVFQEFGKIGKSLKNSISPDEICD
Mflv_0853|M.gilvum_PYR-GCK RGSYVPAAEVIERDGKFVWPGPDGETEVNQEFGKIGKSLKNSVSPDEICD
Mvan_6054|M.vanbaalenii_PYR-1 RGSYVPAAEVVERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICD
MSMEG_6917|M.smegmatis_MC2_155 RGTYVPAAEVIERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICD
TH_0509|M.thermoresistible__bu RGSYVPAAEVIERDGRFYWPGPDGEIEVKQEFGKIGKSLKNSISPDEICD
MAB_4923c|M.abscessus_ATCC_199 RGMYVPAAEVTEENGKFFYQG----AEVQQEFGKIGKSLKNSISPDDICD
:* **** :* :... * * ** *************:***:***
Mb0042|M.bovis_AF2122/97 AYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGET
Rv0041|M.tuberculosis_H37Rv AYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGET
MMAR_0057|M.marinum_M DYGADTLRVYEMSMGPIEASRPWATKDVIGAYRFLQRVWRLVIDENTGEI
MUL_0056|M.ulcerans_Agy99 DYGADTLRVYEMSMGPIEASRPWATKDVIGAHRFLQRVWRLVIDENTGEI
MLBr_00032|M.leprae_Br4923 EYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDERTGET
MAV_0055|M.avium_104 DYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVDEQTGET
Mflv_0853|M.gilvum_PYR-GCK NYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDENTG-E
Mvan_6054|M.vanbaalenii_PYR-1 DYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVSEETG-E
MSMEG_6917|M.smegmatis_MC2_155 NYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRVVIDETSGNV
TH_0509|M.thermoresistible__bu EYGADTLRVYEMSMGPLEASRPWAPKDVVGAYRFLQRVWRLVVDEETGAT
MAB_4923c|M.abscessus_ATCC_199 NYGADTLRVYEMSMGPLELSRPWATKDVVGAHRFLQRAWRVVVDEETGKI
***************:* *****.***:**:*****.**:*:.* :*
Mb0042|M.bovis_AF2122/97 RVADG--VELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTK
Rv0041|M.tuberculosis_H37Rv RVADG--VELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTK
MMAR_0057|M.marinum_M LVADTP-AELDTDTLRALHRAIAGVAEDYAALRNNTAVAKLIEYTNFLTK
MUL_0056|M.ulcerans_Agy99 LVADTP-AELDTDTLRALHRAIAGVAEDYAALRNNTAVAKLIEYTNFLTK
MLBr_00032|M.leprae_Br4923 RVVDTA-GELDTYTLRTLHRTIAGVSQDYAALRNNTATAKLIEYTNHLTK
MAV_0055|M.avium_104 RVVDGAGRDLPTGTLRLLHRTIAGVSEDYAGLRNNTAVAKLIEYTNHLTK
Mflv_0853|M.gilvum_PYR-GCK TLATED--ALDDDTLRLLHRTIAGTADDYASLRNNTAAAKLIEYTNHLTK
Mvan_6054|M.vanbaalenii_PYR-1 TVVTDD--ALDEDTLRLLHRTIAGTADDYAALRNNTAAAKLIEYTNHLTK
MSMEG_6917|M.smegmatis_MC2_155 RVVEHE--ALSDETLRLLHRTIEGVREDYAALRNNTAAAKLIEYTNHLTK
TH_0509|M.thermoresistible__bu RVAAHE--AVDEQTQRLLHKTIAGVSEDYAALRNNTAAAKLIEYTNHLTK
MAB_4923c|M.abscessus_ATCC_199 RVTTDD--LTSEDTLRALHKTIAGVTEDYAALRNNTAAAKLIEYTNHLTK
:. * * **::* *. :*:*.******.********.***
Mb0042|M.bovis_AF2122/97 KHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAA
Rv0041|M.tuberculosis_H37Rv KHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAA
MMAR_0057|M.marinum_M RHRDAVPRAAIEPLVLMVAPLAPHLAEELWQRLGHTTSLAHGPFPAADPA
MUL_0056|M.ulcerans_Agy99 RHRDAVPRAVIEPLVLMVAPLAPHLAEELWQRLGHTTSLAHGPFPAADPA
MLBr_00032|M.leprae_Br4923 EHRGSVPRVAVEPLVLMLAPLAPHLAEELWLRLGHTTSLANGPFPQADPA
MAV_0055|M.avium_104 EHRDAVPRAAVEPLVLMLAPLAPHMAEELWLRLGHTTSLAHGPFPVADPA
Mflv_0853|M.gilvum_PYR-GCK QS--VTARAALEPLVLMVAPLAPHLAEELWKRLGHEGSLAHGPFPLADER
Mvan_6054|M.vanbaalenii_PYR-1 QS--VTARAALEPLVLMVAPLAPHLAEELWRRLGHDASLAHGPFPVADER
MSMEG_6917|M.smegmatis_MC2_155 EG--VAARAAIEPLVLMVAPLAPHLAEELWKRLGHDTSLAHGPFPEADPQ
TH_0509|M.thermoresistible__bu EN--VTARAAIEPLLLMLAPLAPHLAEELWHRVGNTGSLAHGPFPEADPQ
MAB_4923c|M.abscessus_ATCC_199 DYPEGAPRAAVEPLVLMLAPLAPHLAEELWSLLGRDDSLAHGPFPESDDR
..*..:***: *:******:***** :*. ***:**** :*
Mb0042|M.bovis_AF2122/97 YLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGAT
Rv0041|M.tuberculosis_H37Rv YLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGAT
MMAR_0057|M.marinum_M YLIDDTVEYPVQVNGKVRGRVVVAADADDDAVKAAALADEKVQAFLAGAS
MUL_0056|M.ulcerans_Agy99 YLIDDTVEYPVQVNGKVRGRVVVAADADDDAVKAAALADQKVQAFLAGAS
MLBr_00032|M.leprae_Br4923 YLVDDTVEYPVQVNGKIRGRIVVAADADYDTLKTVALADDKVQQFLAGAT
MAV_0055|M.avium_104 YLVEDTVEYPVQVNGKVRGRVTVAADADRDTLEAAALADEKVLAFLAGAQ
Mflv_0853|M.gilvum_PYR-GCK YLVEDTVEYPVQVNGKVRGRVTVPADAPADAVEAAALAEEKVVAFLDGRT
Mvan_6054|M.vanbaalenii_PYR-1 YLVEDTVEYPVQVNGKVRGRVTVAADAPADAVEAAALADDKVVAFLDGKT
MSMEG_6917|M.smegmatis_MC2_155 YLVEDTIEFPVQVNGKVRGKIVVAADADKAALEAAALADEKVQAFLAGAT
TH_0509|M.thermoresistible__bu YLVEDTVEMPVQVNGKVRGHITVAVDADKATLEAAALADEKVQAFLAGAT
MAB_4923c|M.abscessus_ATCC_199 WLVADTVEYPIQVNGKVRGRITVAADAPKGDIEAAALTEEKVLEFLAGAT
:*: :*:* *:*****:**::.*..*: :::..*:::** ** *
Mb0042|M.bovis_AF2122/97 PRKVIVVAGRLVNLVI
Rv0041|M.tuberculosis_H37Rv PRKVIVVAGRLVNLVI
MMAR_0057|M.marinum_M PRKVIVVAGRLVNLVV
MUL_0056|M.ulcerans_Agy99 PRKVIVVAGRLVNLVV
MLBr_00032|M.leprae_Br4923 PRKVIVVAGRLISLVI
MAV_0055|M.avium_104 PRKVIVVPGRLVNLVV
Mflv_0853|M.gilvum_PYR-GCK PKKVIVVAGRLVNVVV
Mvan_6054|M.vanbaalenii_PYR-1 PKKVIVVAGRLVNVVL
MSMEG_6917|M.smegmatis_MC2_155 PKKVIVVPGRLVNLVV
TH_0509|M.thermoresistible__bu PKKVIVVPGKLVNLVV
MAB_4923c|M.abscessus_ATCC_199 PKKVIVVPGRMVNLVV
*:*****.*:::.:*: