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M. marinum M MMAR_0057 (leuS)

annotation: leucyl-tRNA synthetase LeuS
coordinates: 55690 - 58620
length: 976

VTESPTTTPGSTSGAPSGVPSGVNDAESDAPRHRYTAELAAGVERTWQQNWARLGTFNVPNPVGSLAPSD
GSPVPEDKLFVQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGRNVLHALGFDAFGLPAEQYAVQTGT
HPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEFYKWTQWIFLQIYNAWFDAAANKARPISELVAEF
DSGARSLVDGRDWSTLSAGERADVIDDHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVFRKR
LRQWMMRITAYSDRLLDDLDVLDWPDQVKTMQRNWIGRSTGASALFTATRSNGETVGLEVFTTRPDTLFG
ATYLVLAPEHDLVDDLVGAGWPAGVDPLWTGGGATPAEAVAAYRRAIAAKSDLERQESKEKTGVFLGSHA
INPATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVIAGGDISQAAYTGDGVLVNS
GFLDGMSVGEAKQAITARLESDGHGQARIEFKLRDWLFARQRYWGEPFPIVYDADGRPHALDESALPVEL
PDVPDYSPVLFDPDDANSEPSPPLGKATEWVHVELDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNA
DRFCAKENETYWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQ
GYIQAFAYTDARGSYVPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRV
YEMSMGPIEASRPWATKDVIGAYRFLQRVWRLVIDENTGEILVADTPAELDTDTLRALHRAIAGVAEDYA
ALRNNTAVAKLIEYTNFLTKRHRDAVPRAAIEPLVLMVAPLAPHLAEELWQRLGHTTSLAHGPFPAADPA
YLIDDTVEYPVQVNGKVRGRVVVAADADDDAVKAAALADEKVQAFLAGASPRKVIVVAGRLVNLVV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0057leuS-100% (976)leucyl-tRNA synthetase LeuS
M. marinum MMMAR_4481metS2e-0731.45% (124) methionyl-tRNA synthetase MetS

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0042leuS0.085.58% (978) leucyl-tRNA synthetase
M. gilvum PYR-GCKMflv_0853leuS0.079.75% (948) leucyl-tRNA synthetase
M. tuberculosis H37RvRv0041leuS0.085.58% (978) leucyl-tRNA synthetase
M. leprae Br4923MLBr_00032leuS0.082.55% (980) leucyl-tRNA synthetase
M. abscessus ATCC 19977MAB_4923cleuS0.076.19% (949) leucyl-tRNA synthetase
M. avium 104MAV_0055leuS0.085.36% (977) leucyl-tRNA synthetase
M. smegmatis MC2 155MSMEG_6917leuS0.081.05% (950) leucyl-tRNA synthetase
M. thermoresistible (build 8)TH_0509leuS0.079.77% (949) PROBABLE LEUCYL-tRNA SYNTHETASE LEUS (LEUCINE--tRNA LIGASE)
M. ulcerans Agy99MUL_0056leuS0.099.39% (976) leucyl-tRNA synthetase
M. vanbaalenii PYR-1Mvan_6054leuS0.079.03% (973) leucyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0057|M.marinum_M               -----------------------MTESPTTTPGSTSGAPSGVPSGVNDAE
MUL_0056|M.ulcerans_Agy99           -----------------------MTESPTTTPGSTSGAPSGVPSGVNDAE
Mb0042|M.bovis_AF2122/97            -----------------------MTESPTAGPG-------GVPR-ADDAD
Rv0041|M.tuberculosis_H37Rv         -----------------------MTESPTAGPG-------GVPR-ADDAD
MLBr_00032|M.leprae_Br4923          -----------------------MTELPTTVPG--------YNSAVAQTD
MAV_0055|M.avium_104                MRNATETNLWPAKPPRRPLYPVQVTESPTTSPA--------TGSGAAAPD
Mflv_0853|M.gilvum_PYR-GCK          -----------------------MTETPIAP------------------L
Mvan_6054|M.vanbaalenii_PYR-1       -----------------------MTETPTGTQS-----------SRETAA
MSMEG_6917|M.smegmatis_MC2_155      -----------------------MTEPATTP---------------TTPD
TH_0509|M.thermoresistible__bu      -----------------------VTDSTSTD------------------T
MAB_4923c|M.abscessus_ATCC_199      -----------------------MTETQHDATD----------------T
                                                           :*:                        

MMAR_0057|M.marinum_M               SDAPRHRYTAELAAGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPED
MUL_0056|M.ulcerans_Agy99           SDAPRHRYTAELAAGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPED
Mb0042|M.bovis_AF2122/97            SDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDD
Rv0041|M.tuberculosis_H37Rv         SDVPRYRYTAELAARLERTWQENWARLGTFNVPNPVGSLAPPDGAAVPDD
MLBr_00032|M.leprae_Br4923          SDAMRYRYTAELAGRIESTWQDNWARLQTFNVPNPVGSLAPPDGSVVPAD
MAV_0055|M.avium_104                SDAPPYRYTAALAGRIEGSWQDTWAKLGTFNVPNPVGSLAPTDGTPVPED
Mflv_0853|M.gilvum_PYR-GCK          DDTPRFRYTAVLAGEIERAWQQQWADSGTFHVDNPVGSLAPADGSAVPAD
Mvan_6054|M.vanbaalenii_PYR-1       DDTPRHRYTAGLAGEIERAWQQRWTQDGTFDVANPVGSLAPADGSAVPAD
MSMEG_6917|M.smegmatis_MC2_155      EQIPRHRYNADLAGQIERAWQETWSDRGTFNVANPVGSLAPTDGSDVPAD
TH_0509|M.thermoresistible__bu      TDTPPFRYTAKLAGEIERRWQQTWAEQGTFHVPNPVGSLAPPDGSPVPAD
MAB_4923c|M.abscessus_ATCC_199      AELPRHRYTAQLAGQIERRWQQTWADRGTFHVPNPVGSLAPTDGTPIPAD
                                     :   .**.* **. :*  **: *:   **.* ********.**: :* *

MMAR_0057|M.marinum_M               KLFVQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGRNVLHALGFDAF
MUL_0056|M.ulcerans_Agy99           KLFVQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGRNVLHALGFDAF
Mb0042|M.bovis_AF2122/97            KLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAF
Rv0041|M.tuberculosis_H37Rv         KLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMVGRNVLHALGFDAF
MLBr_00032|M.leprae_Br4923          KLFVQDMFPYPSGDGLHVGHPLGYIATDVYARYFRMTGHNVLHAMGFDAF
MAV_0055|M.avium_104                KLFVQDMFPYPSGEGLHVGHPLGYIATDVYARYFRMTGRNVLHALGFDAF
Mflv_0853|M.gilvum_PYR-GCK          KMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAF
Mvan_6054|M.vanbaalenii_PYR-1       KMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYYRMTGRNVLHALGFDAF
MSMEG_6917|M.smegmatis_MC2_155      KMFVQDMFPYPSGDGLHVGHPLGYIATDVYARYYRMLGRNVLHALGFDAF
TH_0509|M.thermoresistible__bu      KMFVQDMFPYPSGEGLHVGHPLGYIATDVYARYHRMRGRNVLHALGFDAF
MAB_4923c|M.abscessus_ATCC_199      KMFVQDMFPYPSGDGLHVGHPLGYIATDVYARFHRMRGANVLHALGFDAF
                                    *:***********:***************:**:.** * *****:*****

MMAR_0057|M.marinum_M               GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEF
MUL_0056|M.ulcerans_Agy99           GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEF
Mb0042|M.bovis_AF2122/97            GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDF
Rv0041|M.tuberculosis_H37Rv         GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGFGHDSRRSFSTTDVDF
MLBr_00032|M.leprae_Br4923          GLPAEQYAMQTGTHPRILTEANVVNFRHQLGRLGLGHDSRRTFSTTDVEF
MAV_0055|M.avium_104                GLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRLGLGHDSRRSFSTTDVEF
Mflv_0853|M.gilvum_PYR-GCK          GLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFATTDVDY
Mvan_6054|M.vanbaalenii_PYR-1       GLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFSTTDVDF
MSMEG_6917|M.smegmatis_MC2_155      GLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLGHDTRRSFSTTDVDY
TH_0509|M.thermoresistible__bu      GLPAEQYAVQTGTHPRTRTEANIANFRRQLGRLGLGHDDRRSFSTTDVEY
MAB_4923c|M.abscessus_ATCC_199      GLPAEQYAVQTGTHPRVRTEANIVNYKRQLGRLGLGHDSRRSFATTDVDF
                                    ********:*******  ****:.*:::******:*** **:*:****::

MMAR_0057|M.marinum_M               YKWTQWIFLQIYNAWFDAAANKARPISELVAEFDSGARSLVDGRDWSTLS
MUL_0056|M.ulcerans_Agy99           YKWTQWIFLQIYNAWFDAAANKARPISELVAEFDSGARSLVDGRDWSTLS
Mb0042|M.bovis_AF2122/97            YRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLT
Rv0041|M.tuberculosis_H37Rv         YRWTQWIFLQIYNAWFDTTANKARPISELVAEFESGARCLDGGRDWAKLT
MLBr_00032|M.leprae_Br4923          YKWTQWIFLQIYNAWFDVAANKARPIAELIAEFDSGERRLVDGRDWATLS
MAV_0055|M.avium_104                YKWTQWIFLQIYNAWFDPAANKARPIAELVAEFDSGARSLDDGRNWSELS
Mflv_0853|M.gilvum_PYR-GCK          YKWTQWIFLQIFNAWFDTDQNRARPIRELIAEFEAGTRQVGDGRSWADLD
Mvan_6054|M.vanbaalenii_PYR-1       YKWTQWIFLQIYNAWFDTAQNKARPVAELIAEFEAGTREVGDGRRWADLD
MSMEG_6917|M.smegmatis_MC2_155      YKWTQWIFLQIYNAWFDRDQNKARRISELVEEFESGKRTLDDGRNWADLS
TH_0509|M.thermoresistible__bu      YKWTQWIFLQIFNAWFDPDQNKARPISELVAEFESGARPVGDGRSWSELP
MAB_4923c|M.abscessus_ATCC_199      YKWTQWIFLQIYNAWYDEQARRARPIQELIAEFDSGTRAPSDGTVWAELS
                                    *:*********:***:*   .:** : **: **::* *   .*  *: * 

MMAR_0057|M.marinum_M               AGERADVIDDHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVF
MUL_0056|M.ulcerans_Agy99           AGERADVIDDHRLVYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVF
Mb0042|M.bovis_AF2122/97            AGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVF
Rv0041|M.tuberculosis_H37Rv         AGERADVIDEYRLVYRADSLVNWCPGLGTVLANEEVTADGRSDRGNFPVF
MLBr_00032|M.leprae_Br4923          AGERADVIDNCRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVF
MAV_0055|M.avium_104                AGERADVIDSHRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVF
Mflv_0853|M.gilvum_PYR-GCK          AGARADLVDAHRLVYLADSVVNWCPGLGTVLANEEVTADGRSERGNFPVF
Mvan_6054|M.vanbaalenii_PYR-1       AGERADVVDSRRLVYLADSVVNWCPGLGTVLANEEVTSDGRSERGNFPVF
MSMEG_6917|M.smegmatis_MC2_155      KGERADVIDGYRLVYRADSMVNWCPGLGTVLANEEVTSEGRSDRGNFPVF
TH_0509|M.thermoresistible__bu      AGERHDIIDSYRLVYRADSMVNWCPGLGTVLANEEVTADGRSDRGNFPVF
MAB_4923c|M.abscessus_ATCC_199      VGARADVIDSYRLVYQSDSVVNWCPGLGTVLANEEVTADGRSERGNFPVF
                                     * * *::*  **** :**:*****************::***:*******

MMAR_0057|M.marinum_M               RKRLRQWMMRITAYSDRLLDDLDVLDWPDQVKTMQRNWIGRSTGASALFT
MUL_0056|M.ulcerans_Agy99           RKRLRQWMMRITAYSDRLLDDLDVLDWPDQVKTMQRNWIGRSTGASALFT
Mb0042|M.bovis_AF2122/97            RKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFS
Rv0041|M.tuberculosis_H37Rv         RKRLRQWMMRITAYADRLLDDLDVLDWPEQVKTMQRNWIGRSTGAVALFS
MLBr_00032|M.leprae_Br4923          RKRLRQWMMRITAYADRLLDDLDLLDWPEQVKTMQRNWIGRSSGATVLFS
MAV_0055|M.avium_104                RKRLRQWMMRITAYSDRLLDDLDLLDWPEPVKTMQRNWIGRSTGAKALFA
Mflv_0853|M.gilvum_PYR-GCK          RKRLRQWMMRITAYSDRLLEDLDVLDWPDKVKTMQRNWIGRSTGAEVQFS
Mvan_6054|M.vanbaalenii_PYR-1       RKRLRQWMMRITAYSDRLLEDLDVLDWPDKVKTMQRNWIGRSTGASVEFG
MSMEG_6917|M.smegmatis_MC2_155      RKRLRQWMMRITAYSDRLLEDLDVLDWPEKVKTMQRNWIGRSTGASVLFA
TH_0509|M.thermoresistible__bu      RKRLRQWMMRITAYAERLLEDLDVLDWPEKVKTMQRNWIGRSTGAAVLFA
MAB_4923c|M.abscessus_ATCC_199      RKRLRQWMMRITAYSDRLIDDLDVLDWPDKVKTMQRNWIGRSQGASVLFG
                                    **************::**::***:****: ************ ** . * 

MMAR_0057|M.marinum_M               ATRS----NGETVGLEVFTTRPDTLFGATYLVLAPEHDLVDDLVGAGWPA
MUL_0056|M.ulcerans_Agy99           ATRS----NGETVGLEVFTTRPDTLFGATYLVLAPEHDLVDDLVGAGWPA
Mb0042|M.bovis_AF2122/97            ARAASD--DGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPA
Rv0041|M.tuberculosis_H37Rv         ARAASD--DGFEVDIEVFTTRPDTLFGATYLVLAPEHDLVDELVAASWPA
MLBr_00032|M.leprae_Br4923          AILSRSDAATTEVDVEVFTTRPDTMFGVTYLVLAPEHNLVDELVATVWPD
MAV_0055|M.avium_104                ATGA----DGAALDIEVFTTRPDTLFGATYMVLAPEHELVDELVAPAWPD
Mflv_0853|M.gilvum_PYR-GCK          TAAG---------DIEVFTTRPDTLFGATYMVLAPEHDLVDRLVASAWPD
Mvan_6054|M.vanbaalenii_PYR-1       TDAG---------DIEVFTTRPDTLFGATYMVLAPEHDLVDRLVADQWPA
MSMEG_6917|M.smegmatis_MC2_155      TAAD---------DIEVFTTRPDTLFGATYLVLAPEHDLVDTLVTDAWPD
TH_0509|M.thermoresistible__bu      TDAG---------DIEVFTTRPDTLFGATYMVLAPEHDMVDQLVADRWPD
MAB_4923c|M.abscessus_ATCC_199      APGAG--------DIEVFTTRPDTLFGATYMVLAPEHPLVDQLAADVWPQ
                                    :            .:*********:**.**:****** :** *.   ** 

MMAR_0057|M.marinum_M               GVDPLWTGGGATPAEAVAAYRRAIAAKSDLERQESKEKTGVFLGSHAINP
MUL_0056|M.ulcerans_Agy99           GVDPLWTGGGATPAEAVAAYRRAIAVKSDLERQESKEKTGVFLGSHAINP
Mb0042|M.bovis_AF2122/97            GVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINP
Rv0041|M.tuberculosis_H37Rv         GVNPLWTYGGGTPGEAIAAYRRAIAAKSDLERQESREKTGVFLGSYAINP
MLBr_00032|M.leprae_Br4923          RTDPRWTYGAATPGAAVAAYRRAIVAKSDLDRQESKEKTGVFLGRYATNP
MAV_0055|M.avium_104                GTDPRWTYGAATPGEAVAAYRRAIASKSDLERQESKAKTGVFLGSYATNP
Mflv_0853|M.gilvum_PYR-GCK          GTDARWTFGAATPAEAVAAYRAGIAAKSDLERQENKTKTGVFLGAYATNP
Mvan_6054|M.vanbaalenii_PYR-1       DVDARWTFGAATPREAVAAYRASIAAKSDLERQENKAKTGVFIGAYATNP
MSMEG_6917|M.smegmatis_MC2_155      GTDERWTYGAATPREAVAAYRTDIAAKSDLERQENKTKTGVFLGAYATNP
TH_0509|M.thermoresistible__bu      GVDPRWTLGAGTPKEAVSTYRAAIAAKSDLERQENKDKTGVFLGAYATNP
MAB_4923c|M.abscessus_ATCC_199      DTDPRWTGGQDSPRAAIEQYRRSIAAKSDLERQENKEKTGVFTGAYATNP
                                     .:  ** *  :*  *:  **  *. ****:***.: ***** * :* **

MMAR_0057|M.marinum_M               ATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVI--
MUL_0056|M.ulcerans_Agy99           ATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVI--
Mb0042|M.bovis_AF2122/97            ANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVI--
Rv0041|M.tuberculosis_H37Rv         ANGEPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARAFGLPIVEVI--
MLBr_00032|M.leprae_Br4923          ATGKPVPIFVADYVLVGYGTGAVMAVPGHDPRDWDFAHKFHLPIVEVI--
MAV_0055|M.avium_104                TNGKPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFAHEFGLPIVEVI--
Mflv_0853|M.gilvum_PYR-GCK          ANGQQVPVFIADYVLAGYGTGAIMAVPSGDQRDWDFATEFGLPIVEVV--
Mvan_6054|M.vanbaalenii_PYR-1       ANAKQVPVFIADYVLAGYGTGAIMAVPGGDQRDWDFATEFGLPIIEVVRP
MSMEG_6917|M.smegmatis_MC2_155      ADGKQVPIFIADYVLAGYGTGAIMAVPGGDQRDWDFAKEFGLPIIEVV--
TH_0509|M.thermoresistible__bu      ANGERIPVFIADYVLLGYGTGAIMAVPGHDQRDWEFAREFGLPIVEVI--
MAB_4923c|M.abscessus_ATCC_199      VSGKPVPVFIADYVLLGYGTGAIMAVPGHDQRDWDFANTFGLPVQEVI--
                                    . .: :*:*:***** ******:****. * ***:**  : **: **:  

MMAR_0057|M.marinum_M               ----------AGGDISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLES
MUL_0056|M.ulcerans_Agy99           ----------AGGDISQAAYTGDGVLVNSGFLDGMSVGEAKQAITARLES
Mb0042|M.bovis_AF2122/97            ----------AGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLES
Rv0041|M.tuberculosis_H37Rv         ----------AGGNISESAYTGDGILVNSDYLNGMSVPAAKRAIVDRLES
MLBr_00032|M.leprae_Br4923          ----------AGSDISEAAYVGDGVLVNSGYLDGMDVATAQEAITARLES
MAV_0055|M.avium_104                ----------AGGDISEGAYAGDGLLVNSGYLDGLDVAAAKEAITARLEA
Mflv_0853|M.gilvum_PYR-GCK          ----------AGGDVTVEAYSGDGTMVNSGFLDGMDVATAKQAMTERLVA
Mvan_6054|M.vanbaalenii_PYR-1       VADRPGEDTGAGGDVSQAAYTGDGVMVNSGFLDGMDVSAAKEAMTERLSA
MSMEG_6917|M.smegmatis_MC2_155      ----------TGGDISEAAYAGDGTMVNSGFLDGMDVASAKEAIIARLEA
TH_0509|M.thermoresistible__bu      ----------AGGNISEAAHTGDGELVNSGFLNGMNVEDAKDAMTSRLAA
MAB_4923c|M.abscessus_ATCC_199      ----------SGGDVTKAAYTGDGVLVNSDYLDGLDIEAAKVEVTRRLVK
                                              :*.:::  *: *** :***.:*:*:.:  *:  :  **  

MMAR_0057|M.marinum_M               DGHGQARIEFKLRDWLFARQRYWGEPFPIVYDADGRPHALDESALPVELP
MUL_0056|M.ulcerans_Agy99           DGYGQARIEFKLRDWLFARQRYWGEPFPIVYDADGRPHALDESALPVELP
Mb0042|M.bovis_AF2122/97            AGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELP
Rv0041|M.tuberculosis_H37Rv         AGRGRARIEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELP
MLBr_00032|M.leprae_Br4923          EGRGHARIEFKLRDWLFARQRYWGEPFPIIYDSDGRPHALDEAALPVELP
MAV_0055|M.avium_104                EGRGCARVEFKLRDWLFARQRYWGEPFPIVYDSDGRPHALDEAALPVELP
Mflv_0853|M.gilvum_PYR-GCK          DGRGRARVEYKLRDWLFARQRYWGEPFPVVYDSEGRAHGLPEGMLPVELP
Mvan_6054|M.vanbaalenii_PYR-1       DGRGRERVEYKLRDWLFARQRYWGEPFPIVYDADDRAHGLPEELLPVELP
MSMEG_6917|M.smegmatis_MC2_155      DGRGKRRVEYKLRDWLFARQRYWGEPFPIVYDADGRAHPLPESALPVELP
TH_0509|M.thermoresistible__bu      EGRGEARVEYKLRDWLFARQRYWGEPFPIVYDSDGRPHPLPESMLPVELP
MAB_4923c|M.abscessus_ATCC_199      DGRGESRIEYKLRDWLFARQRYWGEPFPIVYDEDGRPRALGENVLPVELP
                                     * *  *:*:******************::** :.*.: * *  ******

MMAR_0057|M.marinum_M               DVPDYSPVLFDPDDANSEPSPPLGKATEWVHVELDLGDGLKPYSRDTNVM
MUL_0056|M.ulcerans_Agy99           DVPDYSPVLFDPDDANSEPSPPLGKATEWLHVELDLGDGLKPYSRDTNVM
Mb0042|M.bovis_AF2122/97            DVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVM
Rv0041|M.tuberculosis_H37Rv         DVPDYSPVLFDPDDADSEPSPPLAKATEWVHVDLDLGDGLKPYSRDTNVM
MLBr_00032|M.leprae_Br4923          DVPYYSPVLFDPDDADSEPSPPLAKATEWVHVELDLGDGLKPYSRDTNVM
MAV_0055|M.avium_104                DVPDYSPVLFDPDDADSEPSPPLAKATDWVHVELDLGDGLKPYSRDTNVM
Mflv_0853|M.gilvum_PYR-GCK          DVPDYSPVSFDPDDAGSEPSPPLGKVTDWVNVDLDLGDGLKPYTRDTNVM
Mvan_6054|M.vanbaalenii_PYR-1       DVPDYSPVLFDPDDADSEPSPPLAKATEWVNVELDLGDGRKRYTRDTNVM
MSMEG_6917|M.smegmatis_MC2_155      DVPDYSPVLFDPDDADSEPSPPLNKATEWVHVELDLGDGLQSYTRDTNVM
TH_0509|M.thermoresistible__bu      DIPDYAPVSFDPDDADSEPSPPLNKATDWVTVELDLGNGLKTYTRDTNVM
MAB_4923c|M.abscessus_ATCC_199      EVEDYAPVSFDPDDASSEPSPPLSKAADWVNVELDLGDGLKHYTRDTNVM
                                    ::  *:** ******.******* *.::*: *:****:* : *:******

MMAR_0057|M.marinum_M               PQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDPGGVDLY
MUL_0056|M.ulcerans_Agy99           PQWAGSSWYELRYTDPHNADRFCAKENETYWMGPRPAEHGPDDPGGVDLY
Mb0042|M.bovis_AF2122/97            PQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLY
Rv0041|M.tuberculosis_H37Rv         PQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPDDPGGVDLY
MLBr_00032|M.leprae_Br4923          PQWAGSSWYELRYTDPHNSERLCAKENEAYWMGPRPTEHGIDDPGGVDLY
MAV_0055|M.avium_104                PQWAGSSWYELRYTDPHNSERFCAKENEAYWMGPRPAEHGPQDPGGVDLY
Mflv_0853|M.gilvum_PYR-GCK          PQWAGSSWYELRYTDPYNSEALCAKENEAYWMGPRPAEHGPDDPGGVDLY
Mvan_6054|M.vanbaalenii_PYR-1       PQWAGSSWYELRYADPHNTEALCAKENEAYWMGPRPAEHGPDDPGGVDLY
MSMEG_6917|M.smegmatis_MC2_155      PQWAGSSWYELRYTDPHNPDEMCAKENEAYWMGPRPDEHGPEDPGGVDLY
TH_0509|M.thermoresistible__bu      PQWAGSSWYELRYCDPHNSEEMCAKENEAYWMGPRPEIHGPDDPGGVDLY
MAB_4923c|M.abscessus_ATCC_199      PQWAGSSWYELRYADPDNAEAFCDKENEAYWLGPRPAEHGPNDPGGVDLY
                                    ************* ** *.: :* ****:**:****  ** :********

MMAR_0057|M.marinum_M               VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDA
MUL_0056|M.ulcerans_Agy99           VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDA
Mb0042|M.bovis_AF2122/97            VGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDA
Rv0041|M.tuberculosis_H37Rv         VGGAEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAYAYTDA
MLBr_00032|M.leprae_Br4923          VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLINQGYIQAFAYTDA
MAV_0055|M.avium_104                VGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDS
Mflv_0853|M.gilvum_PYR-GCK          VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDS
Mvan_6054|M.vanbaalenii_PYR-1       VGGVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDA
MSMEG_6917|M.smegmatis_MC2_155      VGGVEHAVLHLLYSRFWHKVLYDLGYVSSREPYRRLVNQGYIQAFAYTDS
TH_0509|M.thermoresistible__bu      VGGVEHAVLHLLYARFWHKVLYDLGHVTSREPYRRLVNQGYIQAYAYTDP
MAB_4923c|M.abscessus_ATCC_199      VGGMEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLLNQGYIQAHAYTDA
                                    *** *********:***********:*:******:*:*******.****.

MMAR_0057|M.marinum_M               RGSYVPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICD
MUL_0056|M.ulcerans_Agy99           RGSYVPAEEVIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICD
Mb0042|M.bovis_AF2122/97            RGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICD
Rv0041|M.tuberculosis_H37Rv         RGSYVPAEQVIERGDRFVYPGPDGEVEVFQEFGKIGKSLKNSVSPDEICD
MLBr_00032|M.leprae_Br4923          HGSYVPANQVFQRGDGFFCPGPDGEIEVFQEFGKIGKSLKNSVSPDEICD
MAV_0055|M.avium_104                RGSYVPAEEVVERDGRFFYRGPDGEIEVFQEFGKIGKSLKNSISPDEICD
Mflv_0853|M.gilvum_PYR-GCK          RGSYVPAAEVIERDGKFVWPGPDGETEVNQEFGKIGKSLKNSVSPDEICD
Mvan_6054|M.vanbaalenii_PYR-1       RGSYVPAAEVVERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICD
MSMEG_6917|M.smegmatis_MC2_155      RGTYVPAAEVIERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICD
TH_0509|M.thermoresistible__bu      RGSYVPAAEVIERDGRFYWPGPDGEIEVKQEFGKIGKSLKNSISPDEICD
MAB_4923c|M.abscessus_ATCC_199      RGMYVPAAEVTEENGKFFYQG----AEVQQEFGKIGKSLKNSISPDDICD
                                    :* **** :* :... *   *     ** *************:***:***

MMAR_0057|M.marinum_M               DYGADTLRVYEMSMGPIEASRPWATKDVIGAYRFLQRVWRLVIDENTGEI
MUL_0056|M.ulcerans_Agy99           DYGADTLRVYEMSMGPIEASRPWATKDVIGAHRFLQRVWRLVIDENTGEI
Mb0042|M.bovis_AF2122/97            AYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGET
Rv0041|M.tuberculosis_H37Rv         AYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDEHTGET
MLBr_00032|M.leprae_Br4923          EYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDERTGET
MAV_0055|M.avium_104                DYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVDEQTGET
Mflv_0853|M.gilvum_PYR-GCK          NYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDENTG-E
Mvan_6054|M.vanbaalenii_PYR-1       DYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRLVVSEETG-E
MSMEG_6917|M.smegmatis_MC2_155      NYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRVVIDETSGNV
TH_0509|M.thermoresistible__bu      EYGADTLRVYEMSMGPLEASRPWAPKDVVGAYRFLQRVWRLVVDEETGAT
MAB_4923c|M.abscessus_ATCC_199      NYGADTLRVYEMSMGPLELSRPWATKDVVGAHRFLQRAWRVVVDEETGKI
                                     ***************:* *****.***:**:*****.**:*:.* :*  

MMAR_0057|M.marinum_M               LVADTP-AELDTDTLRALHRAIAGVAEDYAALRNNTAVAKLIEYTNFLTK
MUL_0056|M.ulcerans_Agy99           LVADTP-AELDTDTLRALHRAIAGVAEDYAALRNNTAVAKLIEYTNFLTK
Mb0042|M.bovis_AF2122/97            RVADG--VELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTK
Rv0041|M.tuberculosis_H37Rv         RVADG--VELDIDTLRALHRTIVGVSEDFAALRNNTATAKLIEYTNHLTK
MLBr_00032|M.leprae_Br4923          RVVDTA-GELDTYTLRTLHRTIAGVSQDYAALRNNTATAKLIEYTNHLTK
MAV_0055|M.avium_104                RVVDGAGRDLPTGTLRLLHRTIAGVSEDYAGLRNNTAVAKLIEYTNHLTK
Mflv_0853|M.gilvum_PYR-GCK          TLATED--ALDDDTLRLLHRTIAGTADDYASLRNNTAAAKLIEYTNHLTK
Mvan_6054|M.vanbaalenii_PYR-1       TVVTDD--ALDEDTLRLLHRTIAGTADDYAALRNNTAAAKLIEYTNHLTK
MSMEG_6917|M.smegmatis_MC2_155      RVVEHE--ALSDETLRLLHRTIEGVREDYAALRNNTAAAKLIEYTNHLTK
TH_0509|M.thermoresistible__bu      RVAAHE--AVDEQTQRLLHKTIAGVSEDYAALRNNTAAAKLIEYTNHLTK
MAB_4923c|M.abscessus_ATCC_199      RVTTDD--LTSEDTLRALHKTIAGVTEDYAALRNNTAAAKLIEYTNHLTK
                                     :.          * * **::* *. :*:*.******.********.***

MMAR_0057|M.marinum_M               RHRDAVPRAAIEPLVLMVAPLAPHLAEELWQRLGHTTSLAHGPFPAADPA
MUL_0056|M.ulcerans_Agy99           RHRDAVPRAVIEPLVLMVAPLAPHLAEELWQRLGHTTSLAHGPFPAADPA
Mb0042|M.bovis_AF2122/97            KHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAA
Rv0041|M.tuberculosis_H37Rv         KHRDAVPRAAVEPLVQMLAPLAPHIAEELWLRLGNTTSLAHGPFPKADAA
MLBr_00032|M.leprae_Br4923          EHRGSVPRVAVEPLVLMLAPLAPHLAEELWLRLGHTTSLANGPFPQADPA
MAV_0055|M.avium_104                EHRDAVPRAAVEPLVLMLAPLAPHMAEELWLRLGHTTSLAHGPFPVADPA
Mflv_0853|M.gilvum_PYR-GCK          QS--VTARAALEPLVLMVAPLAPHLAEELWKRLGHEGSLAHGPFPLADER
Mvan_6054|M.vanbaalenii_PYR-1       QS--VTARAALEPLVLMVAPLAPHLAEELWRRLGHDASLAHGPFPVADER
MSMEG_6917|M.smegmatis_MC2_155      EG--VAARAAIEPLVLMVAPLAPHLAEELWKRLGHDTSLAHGPFPEADPQ
TH_0509|M.thermoresistible__bu      EN--VTARAAIEPLLLMLAPLAPHLAEELWHRVGNTGSLAHGPFPEADPQ
MAB_4923c|M.abscessus_ATCC_199      DYPEGAPRAAVEPLVLMLAPLAPHLAEELWSLLGRDDSLAHGPFPESDDR
                                         ..*..:***: *:******:*****  :*.  ***:**** :*  

MMAR_0057|M.marinum_M               YLIDDTVEYPVQVNGKVRGRVVVAADADDDAVKAAALADEKVQAFLAGAS
MUL_0056|M.ulcerans_Agy99           YLIDDTVEYPVQVNGKVRGRVVVAADADDDAVKAAALADQKVQAFLAGAS
Mb0042|M.bovis_AF2122/97            YLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGAT
Rv0041|M.tuberculosis_H37Rv         YLVDETVEYPVQVNGKVRGRVVVAADTDEETLKAAVLTDEKVQAFLAGAT
MLBr_00032|M.leprae_Br4923          YLVDDTVEYPVQVNGKIRGRIVVAADADYDTLKTVALADDKVQQFLAGAT
MAV_0055|M.avium_104                YLVEDTVEYPVQVNGKVRGRVTVAADADRDTLEAAALADEKVLAFLAGAQ
Mflv_0853|M.gilvum_PYR-GCK          YLVEDTVEYPVQVNGKVRGRVTVPADAPADAVEAAALAEEKVVAFLDGRT
Mvan_6054|M.vanbaalenii_PYR-1       YLVEDTVEYPVQVNGKVRGRVTVAADAPADAVEAAALADDKVVAFLDGKT
MSMEG_6917|M.smegmatis_MC2_155      YLVEDTIEFPVQVNGKVRGKIVVAADADKAALEAAALADEKVQAFLAGAT
TH_0509|M.thermoresistible__bu      YLVEDTVEMPVQVNGKVRGHITVAVDADKATLEAAALADEKVQAFLAGAT
MAB_4923c|M.abscessus_ATCC_199      WLVADTVEYPIQVNGKVRGRITVAADAPKGDIEAAALTEEKVLEFLAGAT
                                    :*: :*:* *:*****:**::.*..*:    :::..*:::**  ** *  

MMAR_0057|M.marinum_M               PRKVIVVAGRLVNLVV
MUL_0056|M.ulcerans_Agy99           PRKVIVVAGRLVNLVV
Mb0042|M.bovis_AF2122/97            PRKVIVVAGRLVNLVI
Rv0041|M.tuberculosis_H37Rv         PRKVIVVAGRLVNLVI
MLBr_00032|M.leprae_Br4923          PRKVIVVAGRLISLVI
MAV_0055|M.avium_104                PRKVIVVPGRLVNLVV
Mflv_0853|M.gilvum_PYR-GCK          PKKVIVVAGRLVNVVV
Mvan_6054|M.vanbaalenii_PYR-1       PKKVIVVAGRLVNVVL
MSMEG_6917|M.smegmatis_MC2_155      PKKVIVVPGRLVNLVV
TH_0509|M.thermoresistible__bu      PKKVIVVPGKLVNLVV
MAB_4923c|M.abscessus_ATCC_199      PKKVIVVPGRMVNLVV
                                    *:*****.*:::.:*: