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VTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLSKL DSAVREGNNAIASHVEADPELEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLV DEGRITAEEAHSHPQRSLIMRALTGHEVEPTLIMREARAGDRYLLCSDGLSDPVSQDTIAEALQIDDVTE SADRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDDDQSAPPNTAAGRASAFNPKRNAAKR VVPQPEEPPPRPRSRRRPIIAATVLVLVVLAGLAVGREIVRNNYYVSENDGTVSIMRGVQGSFLGVSLQE PYLLGCLNNRNELSLISADQSGEPRDCRLLGVDDMRPSERAQVIAGLPSGSLDQAIGQIEELSRSSVLPV CATHTTPTPSPRPAPSPGASLPRPAPPASTPTTTPPESPAASPDPRTGTPAPVPPRTSSAPSPSGSAPPP PPSPSPTVTALPPPPPEPGTNCREVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0808 | - | - | 100% (516) | protein phosphatase 2C domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0271 | - | 4e-14 | 46.15% (91) | hypothetical protein Mflv_0271 |
| M. gilvum PYR-GCK | Mflv_1281 | - | 4e-11 | 41.03% (78) | DNA polymerase III subunits gamma and tau |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0018c | ppp | 0.0 | 72.17% (521) | serine/threonine phosphatase |
| M. tuberculosis H37Rv | Rv0018c | ppp | 0.0 | 72.31% (520) | serine/threonine phosphatase |
| M. leprae Br4923 | MLBr_00020 | - | 0.0 | 69.31% (518) | hypothetical protein MLBr_00020 |
| M. abscessus ATCC 19977 | MAB_0037c | - | 1e-177 | 63.55% (524) | serine/threonine phosphatase Ppp |
| M. marinum M | MMAR_0020 | pstP | 0.0 | 73.46% (520) | serine/threonine phosphatase PstP |
| M. avium 104 | MAV_0022 | - | 0.0 | 69.96% (526) | protein phosphatase 2C |
| M. smegmatis MC2 155 | MSMEG_0033 | - | 0.0 | 78.79% (528) | protein phosphatase 2C |
| M. thermoresistible (build 8) | TH_1481 | ftsY | 7e-08 | 32.14% (140) | PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL |
| M. ulcerans Agy99 | MUL_0022 | pstP | 0.0 | 72.88% (520) | serine/threonine phosphatase PstP |
| M. vanbaalenii PYR-1 | Mvan_0027 | - | 0.0 | 86.67% (525) | protein phosphatase 2C domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0808|M.gilvum_PYR-GCK ---MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
Mvan_0027|M.vanbaalenii_PYR-1 ---MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
MSMEG_0033|M.smegmatis_MC2_155 ---MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
MLBr_00020|M.leprae_Br4923 ---MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
MAV_0022|M.avium_104 ---MTLVLRYAARSDRGLVRSNNEDSVYAGARLLALADGMGGHAAGEVAS
Mb0018c|M.bovis_AF2122/97 MALVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
Rv0018c|M.tuberculosis_H37Rv MARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
MMAR_0020|M.marinum_M ---MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
MUL_0022|M.ulcerans_Agy99 ---MTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVAS
MAB_0037c|M.abscessus_ATCC_199 ---MTLVLRYAARSDRGLVRSNNEDSVYAGARLLALADGMGGHAAGEVAS
TH_1481|M.thermoresistible__bu -------------VSEGLWIAIAIIAVVLVAALIVGLVLYRRRRIRLTKR
..** : :* * *:. : .
Mflv_0808|M.gilvum_PYR-GCK QLVIAALAHLDDDEPGGDLLSKLDSAVREGNNAIASHVEADPELEGMGTT
Mvan_0027|M.vanbaalenii_PYR-1 QLVIAALAHLDDDEPGGDLLSKLDSAVREGNSAIAAHVEADPELDGMGTT
MSMEG_0033|M.smegmatis_MC2_155 QLVIAALAHLDDDEPGGDLLSKLHQAVAEGNAAIAAHVEADPELDGMGTT
MLBr_00020|M.leprae_Br4923 QLVIAALAHLDDDEPGGDLLGKLETAVRAGNLAIAAQVEMEPDFEGMGTT
MAV_0022|M.avium_104 QLVIAALAHLDDDEPGGDLLAKLDEAVRAGNAAIAAQVEAEPELEGMGTT
Mb0018c|M.bovis_AF2122/97 QLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTT
Rv0018c|M.tuberculosis_H37Rv QLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTT
MMAR_0020|M.marinum_M QLVIAALAHLDDDEPGGDLLAKLDAAVRSGNSAIAAQVEMEPELEGMGTT
MUL_0022|M.ulcerans_Agy99 QLVIAALAHLDDDEPGGDLLAKLDAAVRSGNSAIAAQVEMEPELEGMGTT
MAB_0037c|M.abscessus_ATCC_199 QLVIAALAPLDDDEPGGDLLDALADAVHAGNGAIADHVRAEPELDGMGTT
TH_1481|M.thermoresistible__bu DEAKPVERGGGYTTSSGITFSQSATPTKAPPTKAAPERIDTTGLPGVGDD
: . .. . ..* : .. * . . : *:*
Mflv_0808|M.gilvum_PYR-GCK LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITA
Mvan_0027|M.vanbaalenii_PYR-1 LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITA
MSMEG_0033|M.smegmatis_MC2_155 LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITA
MLBr_00020|M.leprae_Br4923 LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITA
MAV_0022|M.avium_104 LTAILFAGDRIGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITR
Mb0018c|M.bovis_AF2122/97 LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITP
Rv0018c|M.tuberculosis_H37Rv LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITP
MMAR_0020|M.marinum_M LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITA
MUL_0022|M.ulcerans_Agy99 LTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITA
MAB_0037c|M.abscessus_ATCC_199 LTAFLFAGKRLGMVHIGDSRAYLMRDGELTQISKDDTFVQTLVDEGRITP
TH_1481|M.thermoresistible__bu ATIPRDAPKRP----IADVR--LPEPPAAPPKPPPPAEVPPTEPPAPPVA
* * .* *.* * * . . . : * . . .
Mflv_0808|M.gilvum_PYR-GCK EEAHSHPQRSLIMRALTGHEVEPTLIMREARAGDRYLLCSDGLSDPVSQD
Mvan_0027|M.vanbaalenii_PYR-1 EEAHSHPQRSLIMRALTGHEVEPTLIMREARAGDRYLLCSDGLSDPVSHD
MSMEG_0033|M.smegmatis_MC2_155 EEAHSHPQRSLIMRALTGHEVEPTLIMREAKAGDRYLLCSDGLSDPVSQE
MLBr_00020|M.leprae_Br4923 EEAHSHPQRSLIMRALTGHEVDPTLTMREARAGDRYLLCSDGLSDPVSDE
MAV_0022|M.avium_104 EEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDE
Mb0018c|M.bovis_AF2122/97 EEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDE
Rv0018c|M.tuberculosis_H37Rv EEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDE
MMAR_0020|M.marinum_M EEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDE
MUL_0022|M.ulcerans_Agy99 EEAHSHPQRSLIMRALTGHEVEPTLTIREARAGDRYLLCSDGLSDPVSDE
MAB_0037c|M.abscessus_ATCC_199 EQAHNHPQRSLIMRALTGAPVEPTLIMREAHAGDRYLLCSDGLSDPVSHE
TH_1481|M.thermoresistible__bu TPSPAETAPPVEPEAAPETTPEPEPGAAPAAPQLDEIAPAEGRLDRLRGR
: .. .: .* . :* * . : ::* * :
Mflv_0808|M.gilvum_PYR-GCK TIAEALQIDDVTESADRLIELALRGGGPDNVTVVVADVVDYDYGQTQPIL
Mvan_0027|M.vanbaalenii_PYR-1 TIAEALQIEDVAESADRLIELALRGGGPDNVTVVVADVVDYDYGQTQPIL
MSMEG_0033|M.smegmatis_MC2_155 TIKEALQIEDVAESADRLIELALRGGGPDNVTVVVADVVDYDYGQTQPIL
MLBr_00020|M.leprae_Br4923 TILEALQIPDVAESAYRLIELALRGGGPDNVTVVVADVIDYDYGQTQPIL
MAV_0022|M.avium_104 TILEALQIPDVAEAAYRLIELALRGGGPDNVTVVVADVVDYDYGQTQPIL
Mb0018c|M.bovis_AF2122/97 TILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVDYDYGQTQPIL
Rv0018c|M.tuberculosis_H37Rv TILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVDYDYGQTQPIL
MMAR_0020|M.marinum_M TIHEALQIPDVAESAYRLIELALRGGGPDNVTVVVADVVDYEYGQTQPIL
MUL_0022|M.ulcerans_Agy99 TIHEALQIPDVAESAYRLIELALRGGGPDNVTVVVADVVDYEYGQTQPIL
MAB_0037c|M.abscessus_ATCC_199 TIAEALEIPDVSAAADRLIELALRSGGPDNVTVVVADVVELDYGQTRPIV
TH_1481|M.thermoresistible__bu --------LAKSQTAIGRSMLGLLGGGDLDEESWEEIEDTLLIADLGPVV
: :* *.* .** : .: *::
Mflv_0808|M.gilvum_PYR-GCK AGAVSGDD-DQSAPPNTAAGRASAFNPKRNAAKRVVPQPE------EPPP
Mvan_0027|M.vanbaalenii_PYR-1 AGAVSGDD-DQSDPPNTAAGRASAFNPKRNAAKRVVPQPE------EPPP
MSMEG_0033|M.smegmatis_MC2_155 AGAVSGDD-DQTAPPDTAAGRASAFNPRRNEPKRVIPQPA------EPAR
MLBr_00020|M.leprae_Br4923 AGAVSGEESQQMALPNTAASRASAIVPRKEIAKSMAPQVD------KVHQ
MAV_0022|M.avium_104 AGAVSGDE-DQLTLPNTSAGRASAIRPRDESAKRVAPQPE------TPSR
Mb0018c|M.bovis_AF2122/97 AGAVSGDD-DQLTLPNTAAGRASAISQRKEIVKRVPPQAD------TFSR
Rv0018c|M.tuberculosis_H37Rv AGAVSGDD-DQLTLPNTAAGRASAISQRKEIVKRVPPQAD------TFSR
MMAR_0020|M.marinum_M AGAVSGDD-DQLTLPNTAAGRASAITARKEAVKRVPPQVE------TVHR
MUL_0022|M.ulcerans_Agy99 AGAVSGDD-DQLTLPNTAAGRASAITARKEAVKRVPPQVE------TVHR
MAB_0037c|M.abscessus_ATCC_199 AGAVSTDADTDTPPPNTAAGRAAAIQRALKEPEPAEDESDSETTDSENSK
TH_1481|M.thermoresistible__bu TTSVVEKLREQMAASRVRTEADARAVLREVLISELRPDLD----------
: :* . : . . : : . :
Mflv_0808|M.gilvum_PYR-GCK RPRSRRRPIIAATVLVLVVLAGLAVGREIVRNNYYVSENDGTVSIMRGVQ
Mvan_0027|M.vanbaalenii_PYR-1 RPHSRRRMIIAAAVLVLVVLTGLAVGREIVRNNYYVSEHNGTVSIMRGVQ
MSMEG_0033|M.smegmatis_MC2_155 KPRSRRRMIIAAVLVVLVVVAGLAIGREILRNNYYVAEHDGTVSIMRGVQ
MLBr_00020|M.leprae_Br4923 QRWSQRQTGITLTLLVLLVLAGVAIGRWVIRDNYYIAEYSGKVSIVRGIQ
MAV_0022|M.avium_104 PRWSRRRLFIVIALAVMLVLAGLTVGWWVIQRNYYVAEYNGRISIVRGIQ
Mb0018c|M.bovis_AF2122/97 PRWSGRRLAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAGSVSIMRGIQ
Rv0018c|M.tuberculosis_H37Rv PRWSGRRLAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAGSVSIMRGIQ
MMAR_0020|M.marinum_M PRWSWRRMALVATLVVLLVVAGLFISRAVIRNNYYVAEFNGTVSIMRGIQ
MUL_0022|M.ulcerans_Agy99 PRWSWRRMALVAELVVLLVVAGLFISRAVIRNNYYVAEFDGTVSIMRGIQ
MAB_0037c|M.abscessus_ATCC_199 PKKRRLRWLIAAVLVVLIALAGLAIARRVVLNNYYVSAHEGNVSIMQGVQ
TH_1481|M.thermoresistible__bu --RSVKALPHDDKPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAA
.:: . : . :: *
Mflv_0808|M.gilvum_PYR-GCK GSFLGVSLQEPYLLGCLNNRNELSLISADQSGEPRDCRLLGVDDMRPSER
Mvan_0027|M.vanbaalenii_PYR-1 GSFLGVSLQEPYLLGCLNARNELSLISAGQSQDSLDCRLLGVGDMRPSER
MSMEG_0033|M.smegmatis_MC2_155 GSFLGISLQEPYRLGCLNARNELSLIGANENRDNLGCRLMAVNDMRPSER
MLBr_00020|M.leprae_Br4923 GSLLGMPLHEPYLVGCLNTRNELSLISYGQSGGHLNCQVMTLRDLRPSGG
MAV_0022|M.avium_104 GSLLGVPLQQPYLVGCLNARNELSLISYGQSGGS-NCQLMTLQDLRRPGQ
Mb0018c|M.bovis_AF2122/97 GSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPER
Rv0018c|M.tuberculosis_H37Rv GSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPER
MMAR_0020|M.marinum_M GSFLGMSLHEPYLMGCLNARNELSQISYQQSGEHLDCNLMKLDDLRPPER
MUL_0022|M.ulcerans_Agy99 GSFLGMSLHEPYLMGCLNARNELSQISYQQSGEHLDCNLMKLDDLRPPER
MAB_0037c|M.abscessus_ATCC_199 GSLLGYRLQRPDLVGCLDSRGDMSLVSYGEAASNLSCKYLKVSDLRPSER
TH_1481|M.thermoresistible__bu DTFRAAAADQLETWASRVG----AEVVRGREGADPASVAFDAVDTGIKNG
.:: . .. .. : : . . : *
Mflv_0808|M.gilvum_PYR-GCK AQVIAGLPSGSLDQAIGQIEELSRSSVLPVCATHTTPTPSPRPAPSPG-A
Mvan_0027|M.vanbaalenii_PYR-1 AQVIAGLPSGSLDEAIGQIEELARSSVLPVCAPPAPPSTTRPPAPSPRPA
MSMEG_0033|M.smegmatis_MC2_155 AQVVAGLPGGTLDEAFAQIGELARSSLLPVCAPPRPTTTTRAPAPPPAPP
MLBr_00020|M.leprae_Br4923 AQVQAGLPGGNLDQAESQLRKLLADSLLPTCPPPRATSPPGPFTMPTDSG
MAV_0022|M.avium_104 VQVQTGLPGGSLDQAESQLRQLLAEYLLPLCPPPRATSPPG--AQATRSP
Mb0018c|M.bovis_AF2122/97 AQVRAGLPAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSE
Rv0018c|M.tuberculosis_H37Rv AQVRAGLPAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSE
MMAR_0020|M.marinum_M AQVQAGLPAGSLDNAIGQLRELAANSLLPPCPAPRATSPPESSAPSTASE
MUL_0022|M.ulcerans_Agy99 AQVQAGLPAGSLDNAIGQLRELAANSLLPPCPAPRATSPPEPSAPSTASE
MAB_0037c|M.abscessus_ATCC_199 QQVETGLPGGTLDEAIGQLRQLSKN-ALPPCPPPAPKTPPP-PAPTAAGR
TH_1481|M.thermoresistible__bu ADVVLIDTAGRLHTKTGLMDELGKVKRVVKKRAAVDEVLLVLDATIGQNS
:* ..* *. . : :* : . :
Mflv_0808|M.gilvum_PYR-GCK SLPRPAPPASTPTTTPPESPAASPDPRTGTPAPVPPRTSSAPSPSGS--A
Mvan_0027|M.vanbaalenii_PYR-1 PAPTSTAPQTTGPSTTPRASGPAPAPETPRTVTTTAPSPASPAPVPP--A
MSMEG_0033|M.smegmatis_MC2_155 SSPAPGASG-RGAGESPVPPSPSP---TTTAAPAPSGAPGSPNPPPP--A
MLBr_00020|M.leprae_Br4923 TP-QPTNTASPTST---TPPTITSSSGTAPTNISPTSSPASTAPTTP---
MAV_0022|M.avium_104 VP-ETGGPASP-------APPTTSASPTPSTNATPG--PASSSPAGP---
Mb0018c|M.bovis_AF2122/97 TT-EPNVTSSPAA-----PSPTTSASAPTGTTPAIPTSASPAAPASP--P
Rv0018c|M.tuberculosis_H37Rv TT-EPNVTSSPAS-----PSPTTSAPAPTGTTPAIPTSASPAAPASP--P
MMAR_0020|M.marinum_M TPGQPSVTSSPASTTPPTPSASTTPTTTSGSTAATSTPPTGTSPAAPTSP
MUL_0022|M.ulcerans_Agy99 TPGQPSVTSSPASTTTPTPSASTTPTTTSGSTAATSTPPAGTSPAAPTSP
MAB_0037c|M.abscessus_ATCC_199 TP-----------------TTTSGTPTTTPSKPSPTTSAGPGASTTP---
TH_1481|M.thermoresistible__bu LPQAKVFAEVVDITG----VVLTKLDGTAKGGIVFRVQQELGVPVKL---
: . .
Mflv_0808|M.gilvum_PYR-GCK PPPPPSPSPTVTALPPPPPEPGTNCREVS
Mvan_0027|M.vanbaalenii_PYR-1 SPTPPPPPPTVTALPPPPPEPGTNCREVS
MSMEG_0033|M.smegmatis_MC2_155 SPSP-TPSPTVTALPPPPPQPGTNCRAVS
MLBr_00020|M.leprae_Br4923 ----VGTSQTVTILPPPPPQPGIDCRAVA
MAV_0022|M.avium_104 ----TTTSQTLTALPGPPLQPGIDCRTVA
Mb0018c|M.bovis_AF2122/97 TPWPVTSSPTMAALPPPPPQPGIDCRAAA
Rv0018c|M.tuberculosis_H37Rv TPWPVTSSPTMAALPPPPPQPGIDCRAAA
MMAR_0020|M.marinum_M TPTLTTSSPNVTALPPPPPQPGIDCRAVA
MUL_0022|M.ulcerans_Agy99 TPTSTTSSPNVTALPPPPPQPGIDCRAVA
MAB_0037c|M.abscessus_ATCC_199 ---TTTSTPAPAPLPAPPQEPGVTCRTVS
TH_1481|M.thermoresistible__bu ----VGLGEGPDDLAPFEPAAFVDALLG-
*. . .