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DAFRWPDGKTAAAAFTFDVDAESAVLWGDESVGARMSVMSHQAYGPLVGIPRILDLLEQHQITSTFFVPG HTADRYPEAVRSIVGAGHEIAHHGYLHEQPTALTLEEEIDALDRGLAALADVAGVRPAGYRAPMWDLSWR TPALLAERGFLYDSSLMDADHPYELAVTPGAAQSLVEIPIQWALDDWEQYCFLPDISGSGLIESPRKARE LWQLEFDALRRVGGCWVLTNHPFLTGRPSRAAELGELMRYVLDHDDVWVVSQA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0796 | - | - | 100% (264) | polysaccharide deacetylase |
| M. gilvum PYR-GCK | Mflv_2063 | - | 8e-06 | 32.93% (82) | polysaccharide deacetylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1126 | - | 7e-05 | 29.89% (87) | glycosyl hydrolase |
| M. tuberculosis H37Rv | Rv1096 | - | 7e-05 | 29.89% (87) | glycosyl hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0916c | - | 6e-16 | 27.92% (265) | putative polysaccharide deacetylase |
| M. marinum M | MMAR_1211 | - | 4e-15 | 29.20% (274) | chitinase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1074 | - | 1e-129 | 84.82% (257) | polysaccharide deacetylase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2681 | - | 2e-14 | 28.83% (274) | chitinase |
| M. vanbaalenii PYR-1 | Mvan_0047 | - | 1e-148 | 93.89% (262) | polysaccharide deacetylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0796|M.gilvum_PYR-GCK --------------MDAFRWPDGKTAAAAFTFDVDA--ESAVLWGD----
Mvan_0047|M.vanbaalenii_PYR-1 -------------MMDRFRWPDGKTAAAAFTFDVDA--ESAILWGN----
MSMEG_1074|M.smegmatis_MC2_155 ---------MASESAPGLVWPEGKVAAAAFTFDVDA--ESAILWGN----
MMAR_1211|M.marinum_M MTGYPRDMTGYGRTPPDPQWPGGALIAVQFVLNYEEGAESSVLDGDSGSE
MUL_2681|M.ulcerans_Agy99 MTGYPRDMTGYGRTPPDPQWRGGALIAVQFVLNYEEGAESSVLDGDSGSE
Mb1126|M.bovis_AF2122/97 -------MPKRPDNQTWRYWRTVTGVVVAGAVLVVGGLSGRVTRAEN---
Rv1096|M.tuberculosis_H37Rv -------MPKRPDNQTWRYWRTVTGVVVAGAVLVVGGLSGRVTRAEN---
MAB_0916c|M.abscessus_ATCC_199 -------------MRQTGWGPDGRRAAACITFDHLGEAAEIQIGALP---
.. .. .
Mflv_0796|M.gilvum_PYR-GCK ----ESVGAR------MSVMSHQAYGPLVGIPRILDLLEQHQITSTFFVP
Mvan_0047|M.vanbaalenii_PYR-1 ----ESVGAR------MSVMSHQAYGPLVGIPRILDLLEQHQVPSTFFVP
MSMEG_1074|M.smegmatis_MC2_155 ----EAVGAR------MSVMSHQAYGPLVGVPRILDLLDRHQIASTFFVP
MMAR_1211|M.marinum_M TFLSEIVPAQSFPNRHMSMESLYEYGSRAGVWRVLRVCEQSGVPLTIFAV
MUL_2681|M.ulcerans_Agy99 TFLSEIVPAQSFPNRHMSMESLYEYGSRAGVWRVLRVCEQSGVPLTIFAV
Mb1126|M.bovis_AF2122/97 ------LSCS----VIKCVALTFDDGPGPYTDRLLHILTDNDAKATFFLI
Rv1096|M.tuberculosis_H37Rv ------LSCS----VIKCVALTFDDGPGPYTDRLLHILTDNDAKATFFLI
MAB_0916c|M.abscessus_ATCC_199 ----------------PDTVVGAHPSVTHCLPALLAALAERSTACTFYVE
. :* *::
Mflv_0796|M.gilvum_PYR-GCK GHTADRYPEAVRSIVGAGHEIAHHGYLHEQPTALTLEEEIDALDRGLAAL
Mvan_0047|M.vanbaalenii_PYR-1 GHTADRYPEAVRSIVAAGHEIAHHGYLHEQPTALTLEQEIDALDRGLAAL
MSMEG_1074|M.smegmatis_MC2_155 GHTAHRYPDAVRAIVAAGHEVAHHGYLHEQPTALTLEEEIEALDRGLEAL
MMAR_1211|M.marinum_M AQAMQRNPEVAKVFRELGHEIACHGLRWKSYQEIDRDTERAHLSEAVRIH
MUL_2681|M.ulcerans_Agy99 AQAMQRNPEVAKGFRELGHEIACHGLRWKSYQEIDRDTERAHLSEAVRIH
Mb1126|M.bovis_AF2122/97 GNKVAANPAGARRIADAGMEIGSHTWEHPNMTTIPPEDIPGQFSRANDVI
Rv1096|M.tuberculosis_H37Rv GNKVAANPAGARRIADAGMEIGSHTWEHPNMTTIPPEDIPGQFSRANDVI
MAB_0916c|M.abscessus_ATCC_199 TWNYAHYPRALESILEHGHEIGWHGWLHEPWSKSTGSAIADSIAESLNAF
* . : * *:. * . : ..
Mflv_0796|M.gilvum_PYR-GCK ADVAGVRPAGYRAPMWDLSWRTPALLAERGFLYDSSLMDADHPYELAVTP
Mvan_0047|M.vanbaalenii_PYR-1 ADVAGVRPVGYRAPMWDLSWRTPALLAERDFLYDSSLMDADHPYELAITP
MSMEG_1074|M.smegmatis_MC2_155 AEVAGVTPAGYRAPMWDLSWHTPGLLAERNFLYDSSLMDADVPYELAVG-
MMAR_1211|M.marinum_M HELTGSAPRGWYG-GRDSPHTRELVVEHGGFLYDSDSYADDLPYWVRVG-
MUL_2681|M.ulcerans_Agy99 HELTGSAPRGWYG-GRDSPHTRELVVEHGGFLYDSDSYADDLPYWVRVG-
Mb1126|M.bovis_AF2122/97 AAATGRTPTLYRP---AGGLSNDAVRQAAAKVGQAEILWDVIPFDWIND-
Rv1096|M.tuberculosis_H37Rv AAATGRTPTLYRP---AGGLSNDAVRQAAAKVGQAEILWDVIPFDWIND-
MAB_0916c|M.abscessus_ATCC_199 ER-TGIRPRGARPPGGLLGDHSLDLLAQAGFDHVS---LAGTRSGLQDG-
:* * : :
Mflv_0796|M.gilvum_PYR-GCK GAAQSLVEIPIQWALDD----WEQYCFLPDISGSGLIESPRKARELWQLE
Mvan_0047|M.vanbaalenii_PYR-1 GAQESLVEIPIQWALDD----WEQYCFLPDISGSGLIETPRKARELWQSE
MSMEG_1074|M.smegmatis_MC2_155 --DTSLVEIPIQWALDD----WEQYCFLPDISGSGLIESPRKARELWQLE
MMAR_1211|M.marinum_M --ASDHLVVPYTLDTND----MRFASPAGFSNGDEFFAHLRDAFDVLYAE
MUL_2681|M.ulcerans_Agy99 --ASDHLVVPYTLDTND----MRFASPAGFSNGDEFFAHLRDAFDVLYAE
Mb1126|M.bovis_AF2122/97 ---SNTAATRHMLMTQI----KPGSVVLFHDTYSSTVDVVYQFIPVLKAN
Rv1096|M.tuberculosis_H37Rv ---SNTAATRHMLMTQI----KPGSVVLFHDTYSSTVDVVYQFIPVLKAN
MAB_0916c|M.abscessus_ATCC_199 -----LALLPFAWSTVDGSYYFDSFAKLRVPPGEHAVGAPG-LLAAYDRY
. .
Mflv_0796|M.gilvum_PYR-GCK FDALRRVGGCWVLTNHPFLTGRPSRAAELGELMRY-VLDHDDVWVVSQA-
Mvan_0047|M.vanbaalenii_PYR-1 FDALRKVGGCWVLTNHPFLTGRPSRAAELGELMRY-VLDHDDVWVSSLGA
MSMEG_1074|M.smegmatis_MC2_155 FDALRRAGGCWVLTNHPFLSGRASRAAELDDLMRY-VTEHADVWTTNLGT
MMAR_1211|M.marinum_M GRAGSPK--MLSVGLHCRLVGRPARTAALQRFLDH-VRSHDRVWLARRVE
MUL_2681|M.ulcerans_Agy99 GRAGSPK--MLSVGLHCRLVGRPARTAALQRFLDH-VRSHDRVWLARRVE
Mb1126|M.bovis_AF2122/97 GYRLVTVSELLGPRAPGSSYGSRENGPPVNELRDIPASEIPPLPNTSSPK
Rv1096|M.tuberculosis_H37Rv GYRLVTVSELLGPRAPGSSYGSRENGPPVNELRDIPASEIPPLPNTSSPK
MAB_0916c|M.abscessus_ATCC_199 LDETVASGGLATFVFHVPWQDQPDRVGAVVNLIDR-IADDSRIWLASAGE
. . : : . :
Mflv_0796|M.gilvum_PYR-GCK ------------------------
Mvan_0047|M.vanbaalenii_PYR-1 VAEHVRSLNLSPRSITPPDVPR--
MSMEG_1074|M.smegmatis_MC2_155 LARHVRAQGLTPRSITQPGK----
MMAR_1211|M.marinum_M IAEHWREVHPAPTG----------
MUL_2681|M.ulcerans_Agy99 IAEHWREVHPAPTG----------
Mb1126|M.bovis_AF2122/97 PMSNFPITDIAGQNSGGPNNGA--
Rv1096|M.tuberculosis_H37Rv PMPNFPITDIAGQNSGGPNNGA--
MAB_0916c|M.abscessus_ATCC_199 IADWMRAHPDSVPAVQHVDELPAW