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TIHTADDPAGDDPTPCSPAPDDTLDVGTDKGAGGAGADSEDPEVVDGKHQRDTSRAWRNRMPPQRLALVM GSVAAVTMGALTSWLGFQTHQAHQASEQRQQFVQVGRQGALNLTTIDWQHADVDVKRILDSATGTFYDEF SQRSQPFIDVVNKVKSKSVGTITEAGLESHSRDTAQVLVAVSVKTTVGDGPEQEPRAWRMRVTVQKVGND AKVADVEFVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0646 | - | - | 100% (221) | hypothetical protein Mflv_0646 |
| M. gilvum PYR-GCK | Mflv_2107 | - | 1e-55 | 52.24% (201) | hypothetical protein Mflv_2107 |
| M. gilvum PYR-GCK | Mflv_2526 | - | 1e-21 | 30.97% (155) | hypothetical protein Mflv_2526 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1398c | - | 3e-29 | 36.56% (186) | hypothetical protein Mb1398c |
| M. tuberculosis H37Rv | Rv1972 | - | 3e-45 | 49.73% (185) | mce associated membrane protein |
| M. leprae Br4923 | MLBr_02597 | - | 5e-09 | 28.82% (170) | hypothetical protein MLBr_02597 |
| M. abscessus ATCC 19977 | MAB_4593c | - | 1e-10 | 22.12% (226) | hypothetical protein MAB_4593c |
| M. marinum M | MMAR_4057 | - | 5e-60 | 58.71% (201) | Mce associated membrane protein |
| M. avium 104 | MAV_2538 | - | 2e-58 | 69.62% (158) | hypothetical protein MAV_2538 |
| M. smegmatis MC2 155 | MSMEG_0352 | - | 4e-42 | 47.80% (182) | hypothetical protein MSMEG_0352 |
| M. thermoresistible (build 8) | TH_2113 | - | 6e-42 | 39.62% (212) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3924 | - | 1e-59 | 55.87% (213) | Mce associated membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0519 | - | 1e-125 | 99.55% (220) | hypothetical protein Mvan_0519 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0646|M.gilvum_PYR-GCK ----------------------------------MTIHTADDPAGDDPTP
Mvan_0519|M.vanbaalenii_PYR-1 ----------------------------------MTIHTADDPAGDDPTP
MMAR_4057|M.marinum_M ---------------------MSDSTTLEEQPEPAEVVEPEGESGQAGVP
MUL_3924|M.ulcerans_Agy99 ---------------------MSDSTTLEEQPEPAEVVEPEGESGQAGVP
MAV_2538|M.avium_104 --------------------------------------------------
Rv1972|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0352|M.smegmatis_MC2_155 --------------------------MAV---DVDTAR---------HEL
TH_2113|M.thermoresistible__bu --------------------------MAEPTPDQDDVRDPDATESTSAEL
Mb1398c|M.bovis_AF2122/97 MAETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREA
MAB_4593c|M.abscessus_ATCC_199 ----------------MADDAADKDAKNADESAVTSDAEKAESSAPSSAA
MLBr_02597|M.leprae_Br4923 --------------------------------------------------
Mflv_0646|M.gilvum_PYR-GCK CSPAPDDTLDVGTDKG----AGGAGADSEDPEVVDGKHQRDT-----SRA
Mvan_0519|M.vanbaalenii_PYR-1 CSPALDDTLDVGTDKG----AGGAGADSEDPEVVDGKHQRDT-----SRA
MMAR_4057|M.marinum_M EAQPRDEDQDETADETQDETQEDADADPEAGEDDAQASDGEQ-----ESP
MUL_3924|M.ulcerans_Agy99 EAQPRDEDQDETADET----QEDADADPEAGEDDAQASDGEQ-----ESP
MAV_2538|M.avium_104 -MEARDDE------------VEDYDAS----VDDAAEPDAED-----PAP
Rv1972|M.tuberculosis_H37Rv MSVAVDSD------------AEDDAVS------EIAEAAGVS-----PAP
MSMEG_0352|M.smegmatis_MC2_155 TQPGQADDQETD-----EKSGVDTDSR----------EPTS-------AQ
TH_2113|M.thermoresistible__bu AATGADADGETAAAADTDSPGLGTESEKAGPGEERDTEPATNPEHGAGKS
Mb1398c|M.bovis_AF2122/97 LAMAPAEDENVPEEYADWEDAEDYDDYDDYEAADQEAARSASWR---RRL
MAB_4593c|M.abscessus_ATCC_199 VESTAEGTTEAATAEVADFDAEDSEKTKDSGAVEDSDDEDISLEPD-EEE
MLBr_02597|M.leprae_Br4923 --------------------MSPRRKFQAGEGLLLVSHTVAS--------
Mflv_0646|M.gilvum_PYR-GCK WRNRMPPQRLALVMGSVAAVTMGALTSWLGFQTHQAHQASEQRQQFVQVG
Mvan_0519|M.vanbaalenii_PYR-1 WRNRMPPQRLALVMGSVAAVTMGALTSWLGFQTHQAHQASEQRQQFVQVG
MMAR_4057|M.marinum_M -KPAPSKVRLAIVVGLAAVVAMAALASWFGFHAYQSHQADQQRKLYVQVA
MUL_3924|M.ulcerans_Agy99 -KPAPSKVRLAIVVGLAAVVAMAALASWFGFHAYQSHQADQQRKLYVQVA
MAV_2538|M.avium_104 AKKLRSPALLATVFGLVTVVGLAALGGWFGYQTYQSHQAQQQRELMVRIG
Rv1972|M.tuberculosis_H37Rv AKPSMSAPRRMLLFGLVVVVALAVLLCCWGFRVQRARHAQDQRGHFLQAA
MSMEG_0352|M.smegmatis_MC2_155 VRG----VRGALVIGVLLLAIVGGATGWLVWQTQRAEQDQRMNEMLLQAG
TH_2113|M.thermoresistible__bu VRGWITPIRLAGIIGLVLVLALGGAVGWLGYRTYQMQRDADLRAQFLEAG
Mb1398c|M.bovis_AF2122/97 RVRLPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQQRAAAFAAGA
MAB_4593c|M.abscessus_ATCC_199 NPKRIRGRHWALTAAAIVAIAIVALAAIIGRLYEEQRIEEQSSREALAAA
MLBr_02597|M.leprae_Br4923 --QRRWGLPLAATFAALVMVAAITASTLMSISHASRELAVAKDQQVLSYV
.
Mflv_0646|M.gilvum_PYR-GCK RQGALNLTTIDWQHADVDVKRILDSATGTFYDEFSQRSQPFIDVVNKVKS
Mvan_0519|M.vanbaalenii_PYR-1 RQGALNLTTIDWQHADVDVKRILDSATGTFYDEFSQRSQPFIDVVNKVKS
MMAR_4057|M.marinum_M RQGAINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIQVVQHFQS
MUL_3924|M.ulcerans_Agy99 RQGAINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIKVVQHFQS
MAV_2538|M.avium_104 RQGALNLTTIDWQHADADVQRILDSATGTFYDDFSHRSKPFIDVVKKAQS
Rv1972|M.tuberculosis_H37Rv RQCALNLTTIDWRNAEADVRRILDGATGEFYNDFAQRSQPFVEVLRHAKA
MSMEG_0352|M.smegmatis_MC2_155 REAAVNLTTMDFEHIREDIQRVLDGSTGTFYDEFEQRAPAFEEVVTKTQS
TH_2113|M.thermoresistible__bu RQGAFALTNVNWEQADADVQRILDAATGSFYDDMQRRAPSYTELVKQAQS
Mb1398c|M.bovis_AF2122/97 KQGVINMNSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKV
MAB_4593c|M.abscessus_ATCC_199 QEFANVMINVDSAKLDESSNKTLERSTGDFKQKYSESSTTLRQVMIENKA
MLBr_02597|M.leprae_Br4923 KWFMTQFTTLDPYHANDYVARILAQATGDFAKQYNEKVNEILLQVAQAEP
: : .:: : : : :** * .. . : . :
Mflv_0646|M.gilvum_PYR-GCK KSVGTITEAGLESHSRD-TAQVLVAVSVKTTVGDGPEQEPRAWRMRVTVQ
Mvan_0519|M.vanbaalenii_PYR-1 KSVGTITEAGLESHSRD-TAQVLVAVSVKTTVGDGPEQEPRAWRMRVTVQ
MMAR_4057|M.marinum_M KSVGTITAAALESESDD-AAQVLVAVSVKTTTAGAPEQRPRAWRMRITVQ
MUL_3924|M.ulcerans_Agy99 KSVGTITAAALESESDD-AAQVLVAVSVKTTTAAAPEQRPRAWRMRITVQ
MAV_2538|M.avium_104 KSVGTITEAGLESQSGS-EAQVLVAVSVKTSNLGAAEQDPRHWRMRVIVQ
Rv1972|M.tuberculosis_H37Rv STVGTITEAGLQTQTAD-TAQALVAVSVQTSNAGEADPVPRAWRMRITVQ
MSMEG_0352|M.smegmatis_MC2_155 KTEGTVTEAGIESVSAD-SARVLVAVSVKTSNIAAPEQRPRLWRMRIDVQ
TH_2113|M.thermoresistible__bu VSKGDVTEVGLESFSEK-QGTVLASVIIESSNVGVPEQQPQAWRMRLIVD
Mb1398c|M.bovis_AF2122/97 VTEGTVNATAVESMNEH-SAVVLVAATSRVTNSAGAKDEPRAWRLKVTVT
MAB_4593c|M.abscessus_ATCC_199 KATGVVVDSAVKSAAPD-KVEVLLFIDQAVSNVAIPDARMDRSRVQITMQ
MLBr_02597|M.leprae_Br4923 -ATGTVLDAGVERWNDDGSANVLVATEVTSKSPDEKQVLENTNRWTATAT
: * : .:: .* . . *
Mflv_0646|M.gilvum_PYR-GCK KVGNDAKVADVEFVP
Mvan_0519|M.vanbaalenii_PYR-1 KVGNDAKVADVEFVV
MMAR_4057|M.marinum_M QVGDEAKVANVEFVP
MUL_3924|M.ulcerans_Agy99 QVGDEAKVANVEFVP
MAV_2538|M.avium_104 KVGNDMKVSNVAFVP
Rv1972|M.tuberculosis_H37Rv RVGDRVKVSDVGFVP
MSMEG_0352|M.smegmatis_MC2_155 RVGDVAKVTNVGFVA
TH_2113|M.thermoresistible__bu KVGSEAKVSAVEFVQ
Mb1398c|M.bovis_AF2122/97 EEGGQYKMSKVEFVP
MAB_4593c|M.abscessus_ATCC_199 KVDGRWLASDVELT-
MLBr_02597|M.leprae_Br4923 REGNQWKISNLLQVI
. .. : : .