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PAVTLYGQIPGGPFFDDLSVGQVFDAAPSMTLTPGVAATHQAILGDRLRLPLDADLSSAVTGSTAALAHP ALVCDVAIGQSTLVTQRVKANLFYRGLTFHRYPVLGDTIYTRTEVVGLKQNSAKPGRAATGLAALRMTTI DGIGRLVLDFYRCAMLPLSSDDVQTGHDDDLSTVGAGGSDAASGTRLVDPTRDWDDAAFRDRVPGPHFDP ALAGTVLRSTADVVSSAPELARLSLNIAATHHDSRVAGKRLVYGGHTIGLALAQASRLLPNLVTVLGWES CDHTGPVHEGDTLYSELRVESVQPRPDGRGGTVALRSTVFAASDETEDRPVLDWRFTGLLF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0445 | - | - | 100% (342) | hypothetical protein Mflv_0445 |
| M. gilvum PYR-GCK | Mflv_2555 | - | 3e-05 | 23.93% (117) | dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0222 | - | 1e-127 | 69.41% (340) | hypothetical protein Mb0222 |
| M. tuberculosis H37Rv | Rv0216 | - | 1e-127 | 69.41% (340) | hypothetical protein Rv0216 |
| M. leprae Br4923 | MLBr_02627 | - | 1e-128 | 69.03% (339) | hypothetical protein MLBr_02627 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0456 | - | 1e-135 | 72.59% (332) | hypothetical protein MMAR_0456 |
| M. avium 104 | MAV_4957 | - | 1e-132 | 72.02% (336) | p40 protein |
| M. smegmatis MC2 155 | MSMEG_0261 | - | 1e-134 | 72.38% (344) | p40 protein |
| M. thermoresistible (build 8) | TH_0720 | - | 4e-06 | 26.61% (124) | POSSIBLE OXIDASE REGULATORY-RELATED PROTEIN |
| M. ulcerans Agy99 | MUL_1107 | - | 1e-133 | 71.69% (332) | hypothetical protein MUL_1107 |
| M. vanbaalenii PYR-1 | Mvan_0222 | - | 1e-151 | 79.22% (332) | hypothetical protein Mvan_0222 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0445|M.gilvum_PYR-GCK MPAVTLYGQIPGGPFFDDLSVGQVFDAAPSMTLTPGVAATHQAILGDRLR
Mvan_0222|M.vanbaalenii_PYR-1 ---------MSGGPHFDDLRVGQVFDSAPSMTLTAGVAATHQAIIGDRMR
MSMEG_0261|M.smegmatis_MC2_155 ---MTAHGRRSGGPYFDDLAVGQVFDTAPSMTLTEGAAAAHQAVIGDRLR
Mb0222|M.bovis_AF2122/97 -MASGYGGIRVGGPYFDDLSKGQVFDWAPGVTLSLGLAAAHQSIVGNRLR
Rv0216|M.tuberculosis_H37Rv -MASGYGGIRVGGPYFDDLSKGQVFDWAPGVTLSLGLAAAHQSIVGNRLR
MAV_4957|M.avium_104 MTSDGYARIREGGPYFDDLSVGQVFDWAPSVTLSSGLAAAHQAILGDRLR
MMAR_0456|M.marinum_M -MHTGYMGIREGGPYFDDLSVGQVFDWAPALTLSAGLAAAHQAILGDRLR
MUL_1107|M.ulcerans_Agy99 -MHTGYMGIREGGPYFDDLSVGQVFDWAPALTLSAGLAAAHQAILGDRLR
MLBr_02627|M.leprae_Br4923 MTANGHAGRREGGPYFDDLSIGQVFDWAPAVTLTSGMAAVHQAILGDRMR
TH_0720|M.thermoresistible__bu --VSEKKVVVQRGLWFEEFETGVLYLHRPGRTITEADNVFFTTLTMNTQA
* *::: * :: *. *:: . . . :: :
Mflv_0445|M.gilvum_PYR-GCK LPLDADLSSAVTGSTAALAHPALVCDVAIGQST--LVTQRVKANLFYRGL
Mvan_0222|M.vanbaalenii_PYR-1 LPLDGELSLSVAGATAPLAHPALVCDVAIGQST--LATQRVKANLFYRGL
MSMEG_0261|M.smegmatis_MC2_155 LSLDAELSSAVTGEPGPLAHPALVCDVAIGQST--LVTQRVKANLFYRGL
Mb0222|M.bovis_AF2122/97 LALDSDLCAAVTGMPGPLAHPGLVCDVAIGQST--LATQRVKANLFYRGL
Rv0216|M.tuberculosis_H37Rv LALDSDLCAAVTGMPGPLAHPGLVCDVAIGQST--LATQRVKANLFYRGL
MAV_4957|M.avium_104 LALDADLCAAVTGLPAPLAHPGLVCDVAIGQST--LVTQRVKANLFYRGL
MMAR_0456|M.marinum_M LALDSSLCGAVTGAPAALAHPGLVCNAAIGQST--LVTQRVKANLFYRGL
MUL_1107|M.ulcerans_Agy99 LALDSSLCGAVTGAPAALAHPGLVCNAAIGQST--LVTQRVKANLFYRGL
MLBr_02627|M.leprae_Br4923 LALDAELSTTVIGTHAMLAHPGLVCDVAIGQST--LVTQRVKANLFYRGL
TH_0720|M.thermoresistible__bu LHLDAAFSDALPPFNARLVNSMFTLSTLVGLSVTQLTQGTIVGNLGFSDI
* **. :. :: . *.:. :. .. :* *. *. : .** : .:
Mflv_0445|M.gilvum_PYR-GCK TFHRYPVLGDTIYTRTEVVGLKQNSAKPGRAATGLAALRMTTIDGIGRLV
Mvan_0222|M.vanbaalenii_PYR-1 TFYRYPVIGDSLFTRTEVVGLRQNTAKPGRAPTGLAALRMTTIDGVGRLI
MSMEG_0261|M.smegmatis_MC2_155 AFHRFPVIGDTLTTRTEVVGLKQNSNKPGRAPTGLAALRMTTTDHKDRLV
Mb0222|M.bovis_AF2122/97 RFHRFPAVGDTLYTRTEVVGLRANSPKPGRAPTGLAGLRMTTIDRTDRLV
Rv0216|M.tuberculosis_H37Rv RFHRFPAVGDTLYTRTEVVGLRANSPKPGRAPTGLAGLRMTTIDRTDRLV
MAV_4957|M.avium_104 VFHRFPVIGDSLYTRTEVVGLRANSPKPGRAPTGMAALRMITIDQADQLV
MMAR_0456|M.marinum_M TFHRYPLIGDTIYTRTEVVALRANTAKPGRAPTGMAALRMTTIDQADRLV
MUL_1107|M.ulcerans_Agy99 TFHRYPLIGDTIYTRTEVVALRANTAKPRRAPTGMAALRMTTIDQADRLV
MLBr_02627|M.leprae_Br4923 TFHRFPVIGDTLYTSTEVVGLQANSAKPGRPPTGMAALRITTTDQHDRLV
TH_0720|M.thermoresistible__bu AFPKPLFHGDTLYAETEVVDKRPSKSRPGE---GIVTFAHTGRNQHGDVV
* : **:: : **** : .. :* . *:. : : . ::
Mflv_0445|M.gilvum_PYR-GCK LDFYRCAMLPLSSDDVQ---TGHDDDLSTVGAGGSDAASGTRLVDPTRDW
Mvan_0222|M.vanbaalenii_PYR-1 LDFYRCAMLPLSDDTAQ---TGHDDDLSAIGAG---AAP---VADPTADW
MSMEG_0261|M.smegmatis_MC2_155 LDFYRCAMLPLSENGGD---TGYSDDLSAIGAD---ASP-----TPTAHW
Mb0222|M.bovis_AF2122/97 LDFYRCAMLPASPDWKP--GAVPGDDLSRIGADAPAPAA-----DPTAHW
Rv0216|M.tuberculosis_H37Rv LDFYRCAMLPASPDWKP--GAVPGDDLSRIGADAPAPAA-----DPTAHW
MAV_4957|M.avium_104 LDFYRCGMLPASPEFTPEAGSVPHDDLSGIGADVPGPAH-----DPTAQW
MMAR_0456|M.marinum_M LDFYRCAMLPASADWDP--AGAADDDLSGIGADAKPPAI-----DPTAHW
MUL_1107|M.ulcerans_Agy99 LDFYRCAMLPASADWDP--AGAADDDLSGIGADAKPPAI-----DPTAHW
MLBr_02627|M.leprae_Br4923 LDFYRCAMLPASAAWHPHDALNRNDDLANVGADAVASAS-----DPTGQW
TH_0720|M.thermoresistible__bu ATATRKTMVRMRP----------ADDPAQ---------------------
* *: ** :
Mflv_0445|M.gilvum_PYR-GCK DDAAFRDRVPGPHFD---PALAGTVLRSTADVVSSAPELARLSLNIAATH
Mvan_0222|M.vanbaalenii_PYR-1 DAEAFRTRVPGPHFD---PALVGTVGRSTADVVSSAPELARLSLNIAATH
MSMEG_0261|M.smegmatis_MC2_155 DADAYRARVPGPHLDDLRDELAGAVLRSTADVVSSAPELARLTLNIAATH
Mb0222|M.bovis_AF2122/97 DGAVFRKRVPGPHFD---AGIAGAVLHSTADLVSGAPELARLTLNIAATH
Rv0216|M.tuberculosis_H37Rv DGAVFRKRVPGPHFD---AGIAGAVLHSTADLVSGAPELARLTLNIAATH
MAV_4957|M.avium_104 DGDVFRTEVPGPHFD---PALAGSVLHSTGDVVSSAPELARLTLNIAATH
MMAR_0456|M.marinum_M DAEAYRTRVPGPHFD---AGIAGKVMHSTGDLVSSAPELARLTLNIAATH
MUL_1107|M.ulcerans_Agy99 DAEAYRTRVPGPHFD---AGIAGKVMHSTGDLVSSAPELARLTLNIAATH
MLBr_02627|M.leprae_Br4923 DAAAFRERVPGPHFD---AGITGAVLRSTGDIVSSAPDLARLTLNIASTH
TH_0720|M.thermoresistible__bu --------------------------------------------------
Mflv_0445|M.gilvum_PYR-GCK HDSRVAGKRLVYGGHTIGLALAQASRLLPNLVTVLGWESCDHTGPVHEGD
Mvan_0222|M.vanbaalenii_PYR-1 HDSRVAGRRLVYGGHTIGLALAQATRLLPNLVTVLGWESCDHTGPVYEND
MSMEG_0261|M.smegmatis_MC2_155 HDWRSGGRRLVYGGHTIGLALAQATRLLPNLVTVLGWESCDHTGPVHEGD
Mb0222|M.bovis_AF2122/97 HDWRVSGRRLVYGGHTIGLALAQATRLLPNLATVLDWESCDHTAPVHEGD
Rv0216|M.tuberculosis_H37Rv HDWRVSGRRLVYGGHTIGLALAQATRLLPNLATVLDWESCDHTAPVHEGD
MAV_4957|M.avium_104 HDSRVGGRRLVYGGHTIGLALAQAARLLPNLVTVLGWRSCDHTGPVHEGD
MMAR_0456|M.marinum_M HDSRVAGQRLVYGGHTIGLALAQASRLMPNLVTVLGWEHCDHTGPVREGD
MUL_1107|M.ulcerans_Agy99 HDSRVAGQRLVYGGHTIGLALAQASRLMPNLATVLGWSHCDHTGPVREGD
MLBr_02627|M.leprae_Br4923 HDSRVRGLRLVYGGHTIGLALAQAGRMLPNLATVLNWRSCDHTGPVHEGD
TH_0720|M.thermoresistible__bu --------------------------------------------------
Mflv_0445|M.gilvum_PYR-GCK TLYSELRVESVQPRPDGRGGTVALRSTVFAAS-DET-EDRPVLDWRFTGL
Mvan_0222|M.vanbaalenii_PYR-1 TLYSDLTVESADPLPDGRGAVLRLRSVVHAAG-DEPGADRQVLEWRFSAL
MSMEG_0261|M.smegmatis_MC2_155 TVFSELHVESIEAN------VVGLRSIVFAAGGPDGGADRQVLDWRFSAL
Mb0222|M.bovis_AF2122/97 TLYSELHIESAQAHADG--GVLGLRSLVYAVSDSASEPDRQVLDWRFSAL
Rv0216|M.tuberculosis_H37Rv TLYSELHIESAQAHADG--GVLGLRSLVYAVSDSASEPDRQVLDWRFSAL
MAV_4957|M.avium_104 TLYSELHIESARPTEHG--GVLGLRSLVYAVSDTPDERDRAVLDWRFDAL
MMAR_0456|M.marinum_M TLYSELHVESAEPTANG--GVLGLRSLVYAVGDS--EPDRQVLDWRFTAL
MUL_1107|M.ulcerans_Agy99 TLYSELHVESAEPTANG--GVLGLRSLVYAVGDS--EPDRQVLDWRFTAL
MLBr_02627|M.leprae_Br4923 TLYSELHVESAEATEQG--GVLGLRSLVYAVSAAG-GSDHLVLDWRFTVL
TH_0720|M.thermoresistible__bu --------------------------------------------------
Mflv_0445|M.gilvum_PYR-GCK LF
Mvan_0222|M.vanbaalenii_PYR-1 HF
MSMEG_0261|M.smegmatis_MC2_155 LF
Mb0222|M.bovis_AF2122/97 QF
Rv0216|M.tuberculosis_H37Rv QF
MAV_4957|M.avium_104 QF
MMAR_0456|M.marinum_M QY
MUL_1107|M.ulcerans_Agy99 QY
MLBr_02627|M.leprae_Br4923 QF
TH_0720|M.thermoresistible__bu --