For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_2555 (-)

annotation: dehydratase
coordinates: 2667156 - 2667650
length: 164

VSGYTKIVVQRGLWFEEFETGVLYQHRPGRTITEADNVLFTTLTMNTQALHLDAAFSDALPPFNQRLVNS
MFTLSTLVGLSVAQLTQGTIVGNLGFGEVAFPKPLFHGDTLYAETEVTDKRESKSRPGEGIVTFSHVGRN
QHGDIVATASRKTMVRKRPEGEAQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2555--100% (164)dehydratase
M. gilvum PYR-GCKMflv_0445-1e-0523.93% (117) hypothetical protein Mflv_0445

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2527c-2e-6373.42% (158) oxidase regulatory-like protein
M. tuberculosis H37RvRv2499c-2e-6373.42% (158) oxidase regulatory-like protein
M. leprae Br4923MLBr_02627-7e-0623.13% (147) hypothetical protein MLBr_02627
M. abscessus ATCC 19977MAB_4379c-4e-7788.96% (154) MaoC-like dehydratase
M. marinum MMMAR_3846-4e-6676.88% (160) hypothetical protein MMAR_3846
M. avium 104MAV_1673-9e-6677.22% (158) MoaC domain-containing protein
M. smegmatis MC2 155MSMEG_4714-3e-8188.82% (161) MoaC domain-containing protein
M. thermoresistible (build 8)TH_0720-5e-7990.26% (154) POSSIBLE OXIDASE REGULATORY-RELATED PROTEIN
M. ulcerans Agy99MUL_3777-3e-6676.88% (160) hypothetical protein MUL_3777
M. vanbaalenii PYR-1Mvan_4088-1e-8495.54% (157) dehydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2527c|M.bovis_AF2122/97           MTKHAGDRESDDAVSACRVAGSTVGRRILQRGLWFEEFQIGTTYLHRPGR
Rv2499c|M.tuberculosis_H37Rv        MTKHAGDRESDDAVSACRVAGSTVGRRILQRGLWFEEFQIGTTYLHRPGR
MMAR_3846|M.marinum_M               -----------------MSEREPAGKSVVQRGLWFEEFEIGTTYLHRPGR
MUL_3777|M.ulcerans_Agy99           -----------------MSEREPAGKSVVQRGLWFEEFEIGTTYLHRPGR
MAV_1673|M.avium_104                -----------------MS--EPV-KSVVQRGLWFEEFEIGTTYLHRPGR
Mflv_2555|M.gilvum_PYR-GCK          ------------------MSGYT--KIVVQRGLWFEEFETGVLYQHRPGR
Mvan_4088|M.vanbaalenii_PYR-1       ------------------MSDMTPNKTVIQRGLWFEEFETGVLYQHRPGR
MSMEG_4714|M.smegmatis_MC2_155      ---------------------MGAKKVVEQRGLWFEEFEIGVIYKHRPGR
MAB_4379c|M.abscessus_ATCC_199      -------MHRQVDAQLGMEVVVSERRTVEQRGLWFEEFETDVLYLHRPGR
TH_0720|M.thermoresistible__bu      ---------------------VSEKKVVVQRGLWFEEFETGVLYLHRPGR
MLBr_02627|M.leprae_Br4923          -------------------MTANGHAGRREGGPYFDDLSIGQVFDWAPAV
                                                                 : * :*:::. .  :   *. 

Mb2527c|M.bovis_AF2122/97           TVTEADNVLFTTLTMNTQSLHLDAAWAGQQPGFRGERLVNSMFTLSTMVG
Rv2499c|M.tuberculosis_H37Rv        TVTEADNVLFTTLTMNTQSLHLDAAWAGQQPGFRGERLVNSMFTLSTMVG
MMAR_3846|M.marinum_M               TVTEADNVLFTTLTMNTQSLHLDAAWAAEQPGFRGERLVNSMFTLSTLVG
MUL_3777|M.ulcerans_Agy99           TVTEADNVLFTTLTMNTQSLHLDAAWAAEQPGFRGERLVNSMFTLSTLVG
MAV_1673|M.avium_104                TITEADNVLFTTLTMNTQSLHLDAAWAAQQPGFRGERLVNSMFTLSTLVG
Mflv_2555|M.gilvum_PYR-GCK          TITEADNVLFTTLTMNTQALHLDAAFSDALPPFN-QRLVNSMFTLSTLVG
Mvan_4088|M.vanbaalenii_PYR-1       TITEADNVLFTTLTMNTQALHLDAAFSDALPPFH-QRLVNSMFTLSTLVG
MSMEG_4714|M.smegmatis_MC2_155      TITEADNVLFTTLTMNTQALHLDAAFSDALPPFN-QRLVNSMFTLSTLVG
MAB_4379c|M.abscessus_ATCC_199      TITEADNVLFTTLTMNTQALHLDAAFSDALPPFN-QRLVNSMFTLSTVVG
TH_0720|M.thermoresistible__bu      TITEADNVFFTTLTMNTQALHLDAAFSDALPPFN-ARLVNSMFTLSTLVG
MLBr_02627|M.leprae_Br4923          TLTSGMAAVHQAILGDRMRLALDAELSTTVIGTH---AMLAHPGLVCDVA
                                    *:*..  ... ::  :   * ***  :      .    : :   *   *.

Mb2527c|M.bovis_AF2122/97           LSVAQLTLGTIVANLGFSEVSFPKPVFHGDTLYAETVCTGKRESKSRPGE
Rv2499c|M.tuberculosis_H37Rv        LSVAQLTLGTIVANLGFSEVSFPKPVFHGDTLYAETVCTGKRESKSRPGE
MMAR_3846|M.marinum_M               LSVAQLTLGTIVANLGFSEVSFPKPVFHGDTLYAETVCAGKRESKSRPGE
MUL_3777|M.ulcerans_Agy99           LSVAQLTLGTIVANLGFSEVSFPKPVFHGDTLYAETVCAGKRESKSRPGE
MAV_1673|M.avium_104                LSVSQLTLGTIVANLGFSEVSFPKPVFHGDTLYAETVCTGKRESKSRPGE
Mflv_2555|M.gilvum_PYR-GCK          LSVAQLTQGTIVGNLGFGEVAFPKPLFHGDTLYAETEVTDKRESKSRPGE
Mvan_4088|M.vanbaalenii_PYR-1       LSVAQLTQGTIVGNLGFGEVAFPKPLFHGDTLYAETEVVDKRESRSRPGE
MSMEG_4714|M.smegmatis_MC2_155      LSVAQLTQGTIVGNLGFSEIAFPKPLFHGDTLYAETEILEKRASKSRPGE
MAB_4379c|M.abscessus_ATCC_199      LSVAQLTQGTIVGNLGFSEIAFPAPLFHGDTLYAESEVIDKRESKSRPGE
TH_0720|M.thermoresistible__bu      LSVTQLTQGTIVGNLGFSDIAFPKPLFHGDTLYAETEVVDKRPSKSRPGE
MLBr_02627|M.leprae_Br4923          IGQSTLVTQRVKANLFYRGLTFHRFPVIGDTLYTSTEVVGLQANSAKPGR
                                    :. : *.   : .** :  ::*    . *****:.:     : . ::**.

Mb2527c|M.bovis_AF2122/97           ---GIVTLEHIARNQHGEVVARAVRTTLVQKQSIK-EAQ-----------
Rv2499c|M.tuberculosis_H37Rv        ---GIVTLEHIARNQHGEVVARAVRTTLVQKQSIK-EAQ-----------
MMAR_3846|M.marinum_M               ---GIVTLEHTGRNQHGDVVARAVRTTLVQKRPSE-EAK-----------
MUL_3777|M.ulcerans_Agy99           ---GIVTLEHTGRNQHGDVVARAVRTTLVQKRPSE-EAK-----------
MAV_1673|M.avium_104                ---GIVTLEHTGRNQHGDVVARAVRTTLVQKRPSDQEAP-----------
Mflv_2555|M.gilvum_PYR-GCK          ---GIVTFSHVGRNQHGDIVATASRKTMVRKRPEG-EAQ-----------
Mvan_4088|M.vanbaalenii_PYR-1       ---GIVTFAHTGRNQHGDIVATASRKTMVRKRPEG-E-------------
MSMEG_4714|M.smegmatis_MC2_155      ---GILTFAHTGRNQHGDIVATAQRKTMVRMRPEG-EA------------
MAB_4379c|M.abscessus_ATCC_199      ---GIVTFAHTGRNQRGDVVATATRKTMVRRRPAE-QPS-----------
TH_0720|M.thermoresistible__bu      ---GIVTFAHTGRNQHGDVVATATRKTMVRMRPAD-DPAQ----------
MLBr_02627|M.leprae_Br4923          PPTGMAALRITTTDQHDRLVLDFYRCAMLPASAAWHPHDALNRNDDLANV
                                       *: ::     :*:. :*    * :::   .                 

Mb2527c|M.bovis_AF2122/97           --------------------------------------------------
Rv2499c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3846|M.marinum_M               --------------------------------------------------
MUL_3777|M.ulcerans_Agy99           --------------------------------------------------
MAV_1673|M.avium_104                --------------------------------------------------
Mflv_2555|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4088|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4714|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4379c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02627|M.leprae_Br4923          GADAVASASDPTGQWDAAAFRERVPGPHFDAGITGAVLRSTGDIVSSAPD
                                                                                      

Mb2527c|M.bovis_AF2122/97           --------------------------------------------------
Rv2499c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3846|M.marinum_M               --------------------------------------------------
MUL_3777|M.ulcerans_Agy99           --------------------------------------------------
MAV_1673|M.avium_104                --------------------------------------------------
Mflv_2555|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4088|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4714|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4379c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02627|M.leprae_Br4923          LARLTLNIASTHHDSRVRGLRLVYGGHTIGLALAQAGRMLPNLATVLNWR
                                                                                      

Mb2527c|M.bovis_AF2122/97           --------------------------------------------------
Rv2499c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3846|M.marinum_M               --------------------------------------------------
MUL_3777|M.ulcerans_Agy99           --------------------------------------------------
MAV_1673|M.avium_104                --------------------------------------------------
Mflv_2555|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4088|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_4714|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4379c|M.abscessus_ATCC_199      --------------------------------------------------
TH_0720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02627|M.leprae_Br4923          SCDHTGPVHEGDTLYSELHVESAEATEQGGVLGLRSLVYAVSAAGGSDHL
                                                                                      

Mb2527c|M.bovis_AF2122/97           -----------
Rv2499c|M.tuberculosis_H37Rv        -----------
MMAR_3846|M.marinum_M               -----------
MUL_3777|M.ulcerans_Agy99           -----------
MAV_1673|M.avium_104                -----------
Mflv_2555|M.gilvum_PYR-GCK          -----------
Mvan_4088|M.vanbaalenii_PYR-1       -----------
MSMEG_4714|M.smegmatis_MC2_155      -----------
MAB_4379c|M.abscessus_ATCC_199      -----------
TH_0720|M.thermoresistible__bu      -----------
MLBr_02627|M.leprae_Br4923          VLDWRFTVLQF