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RGIVLAGGSGTRLYPITLGVSKQLMPVYDKPLIYYPLSTLMMAGIRDILIITTPRDAPDFHRLLGDGSAF GVNLTYAEQEEPEGLAQAFVIGASHIGSDPVALVLGDNIFYGPGLGTGLQRFQNVTGASIFAYWVADPAA YGVVEFDADGNALSLQEKPARPRSHYAVPGLYFYDNDVVEIARHLKKSDRGEYEITEVNQTYLDQGRLRV EVLARGTAWLDTGTFDSLLDASDYVRTLERRQGLKISVPEEVAWRVGFIDDATLEARGKALLKSGYGAYL LELLDR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0285 | - | - | 100% (287) | glucose-1-phosphate thymidylyltransferase |
M. gilvum PYR-GCK | Mflv_3295 | - | e-121 | 71.43% (287) | glucose-1-phosphate thymidylyltransferase |
M. gilvum PYR-GCK | Mflv_4734 | - | 2e-17 | 29.54% (237) | nucleotidyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0341 | rmlA | 1e-135 | 79.09% (287) | glucose-1-phosphate thymidylyltransferase |
M. tuberculosis H37Rv | Rv0334 | rmlA | 1e-135 | 79.09% (287) | alpha-D-glucose-1-phosphate thymidylyltransferase RmlA |
M. leprae Br4923 | MLBr_02503 | rfbA | 1e-131 | 78.75% (287) | glucose-1-phosphate thymidyltransferase |
M. abscessus ATCC 19977 | MAB_4113 | - | 1e-134 | 78.75% (287) | glucose-1-phosphate thymidylyltransferase |
M. marinum M | MMAR_0606 | rmlA | 1e-137 | 79.79% (287) | alpha-D-glucose-1-phosphate thymidylyl- transferase, RmlA |
M. avium 104 | MAV_4820 | rfbA | 1e-132 | 77.35% (287) | glucose-1-phosphate thymidylyltransferase |
M. smegmatis MC2 155 | MSMEG_0384 | rfbA | 1e-134 | 78.75% (287) | glucose-1-phosphate thymidylyltransferase |
M. thermoresistible (build 8) | TH_1924 | rmlA | 1e-137 | 81.53% (287) | ALPHA-D-GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE RMLA |
M. ulcerans Agy99 | MUL_0568 | rmlA | 1e-137 | 79.79% (287) | alpha-D-glucose-1-phosphate thymidylyl- transferase, RmlA |
M. vanbaalenii PYR-1 | Mvan_0603 | - | 1e-142 | 85.02% (287) | glucose-1-phosphate thymidylyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0285|M.gilvum_PYR-GCK MRGIVLAGGSGTRLYPITLGVSKQLMPVYDKPLIYYPLSTLMMAGIRDIL Mvan_0603|M.vanbaalenii_PYR-1 MRGIILAGGSGTRLYPITLGISKQLVPVYDKPLVYYPLSTLMMAGIRDIL Mb0341|M.bovis_AF2122/97 MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQ Rv0334|M.tuberculosis_H37Rv MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQ MMAR_0606|M.marinum_M MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQ MUL_0568|M.ulcerans_Agy99 MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQ MLBr_02503|M.leprae_Br4923 MRGIILAGGSGTRLYPITLGISKQLLPVYDKPMIYYPLSTLMMAGIRDIL MAV_4820|M.avium_104 MRGIILAGGSGTRLHPITTGISKQLLPVYDKPMVYYPLSTLMMAGIRDIL MSMEG_0384|M.smegmatis_MC2_155 MRGIILAGGSGTRLHPLTIGVSKQLLPVYDKPLVYYPLSTLIMAGIRDIL TH_1924|M.thermoresistible__bu MRGIILAGGSGTRLHPITMGVSKQLLPVYDKPLIYYPLSTLIMAGIRDIL MAB_4113|M.abscessus_ATCC_1997 MRGIILAGGSGTRLHPITTGVSKQLLPVYDKPLVYYPLSTLIMAGVRDIL ****:*********:*:* *:****:******::****:**:***:*** Mflv_0285|M.gilvum_PYR-GCK IITTPRDAPDFHRLLGDGSAFGVNLTYAEQEEPEGLAQAFVIGASHIGSD Mvan_0603|M.vanbaalenii_PYR-1 VITTAHDAPDFRRLLGDGSDLGVNLSYAVQDEPDGLAQAFVIGASHIGTD Mb0341|M.bovis_AF2122/97 LITTPHDAPGFHRLLGDGAHLGVNISYATQDQPDGLAQAFVIGANHIGAD Rv0334|M.tuberculosis_H37Rv LITTPHDAPGFHRLLGDGAHLGVNISYATQDQPDGLAQAFVIGANHIGAD MMAR_0606|M.marinum_M LITTPHDAAGFHRLLGDGTHFGVNITYATQDQPDGLAQAFVIGADHIGTD MUL_0568|M.ulcerans_Agy99 LITTPHDAAGFHRLLGDGTHFGVNITYATQDQPDGLAQAFVIGADHIGTD MLBr_02503|M.leprae_Br4923 VITTAHDAPGFKRLLGDGTQFGVNISYATQDHPDGLAQAFVIGANHIGAD MAV_4820|M.avium_104 VITTPHDAAGFVRLLGDGSQFGINITYVTQERPDGLAQAFVLGADHIGND MSMEG_0384|M.smegmatis_MC2_155 VITTPADAPAFRRLLGDGSDFGVNLSYAAQNEPEGLAQAFLIGADHIGND TH_1924|M.thermoresistible__bu VITTPTDAPAFQRLLGDGSAFGVNLRYAEQQEPEGLAQAFVIGADHIGDD MAB_4113|M.abscessus_ATCC_1997 VITTPADAPAFERLLGDGSAFGINLSYAVQPQPEGLAQAFVIGAQHIGTD :***. **. * ******: :*:*: *. * .*:******::**.*** * Mflv_0285|M.gilvum_PYR-GCK PVALVLGDNIFYGPGLGTGLQRFQNVTGASIFAYWVADPAAYGVVEFDAD Mvan_0603|M.vanbaalenii_PYR-1 SVALVLGDNIFYGPGLGTSLQRFQNVSGGAIFAYWVANPSAYGVVEFAED Mb0341|M.bovis_AF2122/97 SVALVLGDNIFYGPGLGTSLKRFQSISGGAIFAYWVANPSAYGVVEFGAE Rv0334|M.tuberculosis_H37Rv SVALVLGDNIFYGPGLGTSLKRFQSISGGAIFAYWVANPSAYGVVEFGAE MMAR_0606|M.marinum_M SVALVLGDNIFYGPGLGTSLRRFQDISGGTIFAYWVANPTAYGVVEFSAD MUL_0568|M.ulcerans_Agy99 SVALVLGDNIFYGPGLGTSLRRFQDISGGTIFAYWVANPTAYGVVEFSAD MLBr_02503|M.leprae_Br4923 TVALVLGDNIFYGPGLGTSLRRFQYVSGGAIFAYCVANPSSYGIVELGID MAV_4820|M.avium_104 SVALVLGDNIFYGPGLGTSLRRFQTITGGAVFAYWVANPSAYGVVEFSDD MSMEG_0384|M.smegmatis_MC2_155 TVALALGDNIFYGPGLGTSLRRFEHVSGGAIFAYWVANPSAYGVVEFDAD TH_1924|M.thermoresistible__bu TVALALGDNIFYGPGLGTSLRRFQNVTGGAIFAYWVANPSAYGVVEFGPD MAB_4113|M.abscessus_ATCC_1997 TAMLALGDNVFYGPGLGTSLRRFENIDGGAIFAYWVANPSAYGVVEFDAA .. *.****:********.*:**: : *.::*** **:*::**:**: Mflv_0285|M.gilvum_PYR-GCK GNALSLQEKPARPRSHYAVPGLYFYDNDVVEIARHLKKSDRGEYEITEVN Mvan_0603|M.vanbaalenii_PYR-1 GTALSLEEKPATPKSHYAVPGLYFYDNDVIEIARGLRRSARGEYEITEVN Mb0341|M.bovis_AF2122/97 GMALSLEEKPVTPKSNYAVPGLYFYDNDVIEIARGLKKSARGEYEITEVN Rv0334|M.tuberculosis_H37Rv GMALSLEEKPVTPKSNYAVPGLYFYDNDVIEIARGLKKSARGEYEITEVN MMAR_0606|M.marinum_M GTALSLEEKPATPKSHYAVPGLYFYDNDVIEIARGLKKSARGEYEITEVN MUL_0568|M.ulcerans_Agy99 GTALSLEEKPATPKSHYAVPGLYFYDNDVIEIARSLKKSARGEYEITEVN MLBr_02503|M.leprae_Br4923 GIALSLEEKPATPKSQYAVPGLYFYDNDVVEIARGLTKSARGEYEITEVN MAV_4820|M.avium_104 GMALSLEEKPKTPKSNYAVPGLYFYDNDVIEIAKGLKKSERGEYEITEVN MSMEG_0384|M.smegmatis_MC2_155 GKAVSLEEKPKTPKSHYAVPGLYFYDNTVIDIARSLKKSARGEYEITEVN TH_1924|M.thermoresistible__bu GKAVSLEEKPKVPKSNYAVPGLYFYDNDVIEIARSLRKSARGEYEITEVN MAB_4113|M.abscessus_ATCC_1997 GVPLSLEEKPATPKSHYAVPGLYFYDNDVIEIARSLQKSARGEYEITEIN * .:**:*** *:*:*********** *::**: * :* ********:* Mflv_0285|M.gilvum_PYR-GCK QTYLDQGRLRVEVLARGTAWLDTGTFDSLLDASDYVRTLERRQGLKISVP Mvan_0603|M.vanbaalenii_PYR-1 QTYLNQGRLSVEVLARGTAWLDTGTFDSLLDAADFVRTIERRQGLKISVP Mb0341|M.bovis_AF2122/97 QVYLNQGRLAVEVLARGTAWLDTGTFDSLLDAADFVRTLERRQGLKVSIP Rv0334|M.tuberculosis_H37Rv QVYLNQGRLAVEVLARGTAWLDTGTFDSLLDAADFVRTLERRQGLKVSIP MMAR_0606|M.marinum_M QAYLNHGRLNVEMLARGTAWLDTGTFDSLLDAADFVRTLERRQGLKVSVP MUL_0568|M.ulcerans_Agy99 QAYLNHGRLNVEMLARGTAWLDTGTFDSLLDAADFVRTLERRQGLKVSVP MLBr_02503|M.leprae_Br4923 QIYLNQGRLTVEVLARGTAWLDTGTFDSLLDASDFVRTLERRQGLKVSVP MAV_4820|M.avium_104 QIYLSRGRLSVEVMARGTAWLDTGTFDSLLDASDFVRTLERRQGLKVSVP MSMEG_0384|M.smegmatis_MC2_155 QIYLNRGQLSVEVLARGTAWLDTGTFDSLLDASDFVRTIELRQGLKVGAP TH_1924|M.thermoresistible__bu QIYLERGQLSVEVLARGTAWLDTGTFDSLLDASDFVRTIERRQGLKIGAP MAB_4113|M.abscessus_ATCC_1997 QIYLDQGRLSVEVLPRGTAWLDTGTFDSLLDASDYVRTIERRQGLKIGVP * **.:*:* **::.*****************:*:***:* *****:. * Mflv_0285|M.gilvum_PYR-GCK EEVAWRVGFIDDATLEARGKALLKSGYGAYLLELLDR------ Mvan_0603|M.vanbaalenii_PYR-1 EEVAWRVGFIDDDALEARAKTLLKSGYGAYLLELLQR------ Mb0341|M.bovis_AF2122/97 EEVAWRMGWIDDEQLVQRARALVKSGYGNYLLELLERN----- Rv0334|M.tuberculosis_H37Rv EEVAWRMGWIDDEQLVQRARALVKSGYGNYLLELLERN----- MMAR_0606|M.marinum_M EEVAWRLGWIDDEQLMRRARSLVKSGYGSYLLELLERN----- MUL_0568|M.ulcerans_Agy99 EEVAWRLGWIDDEQLMRRARSLVKSGYGSYLLELLERN----- MLBr_02503|M.leprae_Br4923 EEVSWRMGWIDDEQLALRAHSLAKSGYGCYLSELLERG----- MAV_4820|M.avium_104 EEVAWQQGWITDEQLSERAQSLLKSGYGGYLLDLLERSRFH-- MSMEG_0384|M.smegmatis_MC2_155 EEIAWRAGFIDDDQLATRAKELLKSGYGHYLLQLLDRE----- TH_1924|M.thermoresistible__bu EEIAWRAGFIDDEQLAARARQLLKSGYGTYLLELLGRERREPF MAB_4113|M.abscessus_ATCC_1997 EEIAWRAGFINDDQLAARAQKLLKSGYGSYLLQLLQRK----- **::*: *:* * * *.: * ***** ** :** *