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HAELDRIGRRLNEPMRIALAGTLKAGKSTLVNALVGETIAPTDATEATRIVTWFRHGPTPKVTANHRGGR RTNVPIARDPHAGGLTFDFARLDPDDVLDLDVEWPASELVDATIIDTPGTSSLSKDVSARTLRLLVPDDG VPRVDAVVFLLRTLNAPDIALLKQIGELVGGSSGALGVIGVASRADEIGAGRIDAMMSAGDVAARFTKEM EQTGICQAVVPVSGLLALTARTLRQSEFGALDKLAGVEPAELAKAMLSVDRFVREDSPLPVDAATRAALL DRFGMFGLRISIAVLRAGVRDSVALAEELLERSGLVALRDVIDQQFAQRSDLLKAHTALLSLRQFVQRNP VYATPRILADIEPLLADTHAFEELRLLSRLRSRPTTLNDDEMASLRRVIGGSGTDVASRLGLPPGDESDG PRAAFAAVQRWRRRADHPLNDPFTARACRAAVRSAEAIVADYARRGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0272 | - | - | 100% (468) | isoniazid inductible gene protein IniC |
| M. gilvum PYR-GCK | Mflv_0273 | - | 6e-11 | 24.52% (363) | hypothetical protein Mflv_0273 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0350 | iniC | 0.0 | 77.90% (466) | isoniazid inductible gene protein INIC |
| M. tuberculosis H37Rv | Rv0343 | iniC | 0.0 | 77.90% (466) | isoniazid inductible gene protein INIC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4282c | - | 1e-169 | 66.88% (468) | isoniazid inductible gene protein IniC |
| M. marinum M | MMAR_0616 | iniC | 0.0 | 79.18% (466) | isoniazid inductible protein IniC |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0698 | - | 0.0 | 87.39% (468) | isoniazid inductible protein IniC |
| M. thermoresistible (build 8) | TH_1301 | - | 0.0 | 85.47% (468) | ISONIAZID INDUCTIBLE GENE PROTEIN INIC |
| M. ulcerans Agy99 | MUL_0581 | iniC | 0.0 | 78.76% (466) | protein IniC |
| M. vanbaalenii PYR-1 | Mvan_0625 | - | 0.0 | 87.08% (472) | isoniazid inductible gene protein IniC |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0350|M.bovis_AF2122/97 MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALA
Rv0343|M.tuberculosis_H37Rv MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALA
MMAR_0616|M.marinum_M MSTSDRVRAILGGTIQAYRGEPAYRQRADVFYELDRIGARLSEPIRIALA
MUL_0581|M.ulcerans_Agy99 MSTSDRVRAILGGTIQAYRGEPAYRQRADVFYELDRIGARLSEPIRIALA
Mflv_0272|M.gilvum_PYR-GCK -----------------------------MHAELDRIGRRLNEPMRIALA
Mvan_0625|M.vanbaalenii_PYR-1 ------MRAILGGTIAAYRADPAYRQRPDLHAELERIGRRLNEPMRIALA
MSMEG_0698|M.smegmatis_MC2_155 MSTGDQVRAILRGTVQAYRGDPAYRHRPDVHNELERIGWQLNQPIRIALA
TH_1301|M.thermoresistible__bu ------VRAILGGTIRAYRAEAAYRDRPDVHNELMRIGARLNEPIRVALA
MAB_4282c|M.abscessus_ATCC_199 MSSVVQARVIISDAMRAYQNDSRYLRVAEPHDELRRIAARLDEPIRVAIA
. :* **. :* :*:*:*:*
Mb0350|M.bovis_AF2122/97 GTLKAGKSTLVNALVGDDIAPTDATEATRIVTWFRHGPTPRVTANHRGGR
Rv0343|M.tuberculosis_H37Rv GTLKAGKSTLVNALVGDDIAPTDATEATRIVTWFRHGPTPRVTANHRGGR
MMAR_0616|M.marinum_M GTLKAGKSTLVNALVGDDIAPTDATEATRIVTGFRHGPTPRVTANHRGGR
MUL_0581|M.ulcerans_Agy99 GTLKAGKSTLVNALVGDDIAPTDATEATRIVTGFRHGPTPRVTANHRGGC
Mflv_0272|M.gilvum_PYR-GCK GTLKAGKSTLVNALVGETIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
Mvan_0625|M.vanbaalenii_PYR-1 GTLKAGKSTLVNALVGDEIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
MSMEG_0698|M.smegmatis_MC2_155 GTLKAGKSTLVNALLGEEIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
TH_1301|M.thermoresistible__bu GTLKAGKSTLVNALVGESIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
MAB_4282c|M.abscessus_ATCC_199 GTLNAGKSTLVNALVGEDIAPTDATEATRIVAWFRHGAAPRVTANLFSGV
***:**********:*: *************: ****.:*:**** .*
Mb0350|M.bovis_AF2122/97 RANVPITRRG-------GLSFDLRRINPAELIDLEVEWPAEELIDATIVD
Rv0343|M.tuberculosis_H37Rv RANVPITRRG-------GLSFDLRRINPAELIDLEVEWPAEELIDATIVD
MMAR_0616|M.marinum_M RVNVPITHRD-------GLSFDLRRLNPAEIADLDVEWPAEELVNTTIID
MUL_0581|M.ulcerans_Agy99 RVNVPITHRD-------GLSFDLRRLNPAEIADLDVEWPAEELVNTTIID
Mflv_0272|M.gilvum_PYR-GCK RTNVPIARD---PHAG-GLTFDFARLDPDDVLDLDVEWPASELVDATIID
Mvan_0625|M.vanbaalenii_PYR-1 RSNVPITRDRADPQGRRGLTFDFASLDPDDVVDLDVEWPAAELIDATIID
MSMEG_0698|M.smegmatis_MC2_155 RSNVPIVRDP----HDRGLTFRFDGLDPGEILDLDVEWPAVELIDTTIID
TH_1301|M.thermoresistible__bu RSNVPITRN-------GGLTFDFANLDPEDIVDLEVEWPAAELIDYTIID
MAB_4282c|M.abscessus_ATCC_199 RQDIPIRREG-------GLSFELDRLDPASVADLDVNWPAPELNEITLID
* ::** : **:* : ::* .: **:*:*** ** : *::*
Mb0350|M.bovis_AF2122/97 TPGTSSLACDASERTLRLLVPADGVPRVDAVVFLLRTLNAADVALLKQIG
Rv0343|M.tuberculosis_H37Rv TPGTSSLACDASERTLRLLVPADGVPRVDAVVFLLRTLNAADVALLKQIG
MMAR_0616|M.marinum_M TPGTSSLNRDTSERTLRLLVPADGVPRVDAVVFLLRTLNAADIALLKQIG
MUL_0581|M.ulcerans_Agy99 TPGTSSLNRDTSERTLRLLVPADGVPRVDAVVFLLRTLNAADIALLKQIG
Mflv_0272|M.gilvum_PYR-GCK TPGTSSLSKDVSARTLRLLVPDDGVPRVDAVVFLLRTLNAPDIALLKQIG
Mvan_0625|M.vanbaalenii_PYR-1 TPGTSSLSQDVSARTLRLLVPDDGVPRVDAVVFLLRTLNAADIALLKQIG
MSMEG_0698|M.smegmatis_MC2_155 TPGTSSLSQDVSERTYRLLVPDDGVPRVDAVVFLLRTLNAADIALLKQIG
TH_1301|M.thermoresistible__bu TPGTSSLNRDVSERTLRLLVPEDGVPRVDAVVFLLRTLNAADIALLKQIG
MAB_4282c|M.abscessus_ATCC_199 TPGTSSLSTDVSERSLALLVPEDGVPRVDAVIFLLRSLNAADIGLLTQIG
******* *.* *: **** *********:****:***.*:.**.***
Mb0350|M.bovis_AF2122/97 GLVGGS-VGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQMGI
Rv0343|M.tuberculosis_H37Rv GLVGGS-VGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQMGI
MMAR_0616|M.marinum_M GLVGDS-AGALGIIGVASRADEIGAGRIDAMSSAQDVAKRFTAELSQTGI
MUL_0581|M.ulcerans_Agy99 GLVGDS-AGALGIIGVASRADEIGAGRIDAMSSAQDVAKRFTAELSQTGI
Mflv_0272|M.gilvum_PYR-GCK ELVGGS-SGALGVIGVASRADEIGAGRIDAMMSAGDVAARFTKEMEQTGI
Mvan_0625|M.vanbaalenii_PYR-1 ELVGGA-AGALGVIGVASRADEIGAGRIDAMMSARDVAQRFTAEMERTGI
MSMEG_0698|M.smegmatis_MC2_155 ELVGGS-SGALGVIGVASRADEIGAGRIDAMMSAKDVAKRFTAEMDKTGI
TH_1301|M.thermoresistible__bu DLVGGS-AGALGVIGVASRADEIGAGRIDAMLSAKDVAKRFTDELERTGV
MAB_4282c|M.abscessus_ATCC_199 KLVGGERGGAVGVVGVVSRADEIGVGRLDAMLSAREVAARFAGEMERTGI
***. **:*::**.*******.**:*** ** :** **: *:.: *:
Mb0350|M.bovis_AF2122/97 CQAVVPVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRR
Rv0343|M.tuberculosis_H37Rv CQAVVPVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRR
MMAR_0616|M.marinum_M CQAVVPVSGLLALTARTLRQSEFAALKKLAGADSTELNKALLSVDRFVRP
MUL_0581|M.ulcerans_Agy99 CQAVVPVSGLLALTARTLRQSEFAALKKLAGADSTELNKALLSVDRFVRP
Mflv_0272|M.gilvum_PYR-GCK CQAVVPVSGLLALTARTLRQSEFGALDKLAGVEPAELAKAMLSVDRFVRE
Mvan_0625|M.vanbaalenii_PYR-1 CQAVVPVSGLLALTARTLRQSEFVALKKLSEVEPAQLAKAMLSVDRFVRA
MSMEG_0698|M.smegmatis_MC2_155 CQAVVPVSGLLAVTARTLRQSEFVALEKLAGVDPAELAKAMLSVDRFVRE
TH_1301|M.thermoresistible__bu CQAVVPVSGLLALTARTLRQSEFVALERLAGVDPAVLTKAMLSVDRFVRE
MAB_4282c|M.abscessus_ATCC_199 CQAVVPVAGLLALTARTLRQAEFVALQRLAELDPQVLAKALLSVDRFVRE
*******:****:*******:** ** :*: : * :*:********
Mb0350|M.bovis_AF2122/97 DS---PLPVDAGIRAQLLERFGMFGIRMSIAVLAAGVTDSTGLAAELLER
Rv0343|M.tuberculosis_H37Rv DS---PLPVDAGIRAQLLERFGMFGIRMSIAVLAAGVTDSTGLAAELLER
MMAR_0616|M.marinum_M DS---PLPVDAGTRAQLLERFGMFGIRISIAGLAAGIADSAGLAAELLER
MUL_0581|M.ulcerans_Agy99 DS---PLPVDAGTRAQLLERFGMFGIRISIAGLAAGIADSAGLAAELLER
Mflv_0272|M.gilvum_PYR-GCK DS---PLPVDAATRAALLDRFGMFGLRISIAVLRAGVRDSVALAEELLER
Mvan_0625|M.vanbaalenii_PYR-1 DSEDTALPVSSGTRAELLDRFGMFGIRIAIAVLRAGVGDSVALADELLER
MSMEG_0698|M.smegmatis_MC2_155 DS---ALPVDAATRAALLDRFGMFGIRISIAVLRAGVSDSVALADELLER
TH_1301|M.thermoresistible__bu DA---DLPVDAATRAALLDRFGMFGIRISIAVLRAGIKDSVALADELLER
MAB_4282c|M.abscessus_ATCC_199 DD---SLPVDAQTRAALLHRFGMFGIRISVAVMRVGVTDATGLAEELLER
* ***.: ** **.******:*:::* : .*: *:..** *****
Mb0350|M.bovis_AF2122/97 SGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADID
Rv0343|M.tuberculosis_H37Rv SGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADID
MMAR_0616|M.marinum_M SGLVALREVIDQQFAQRSDMLKAHTALVSLRRFVQAHPVMATPYVIADID
MUL_0581|M.ulcerans_Agy99 SGLVALREVIDQQFAQRSDMLKAHAALVSLRRFVQAHPVMATPYVIADID
Mflv_0272|M.gilvum_PYR-GCK SGLVALRDVIDQQFAQRSDLLKAHTALLSLRQFVQRNPVYATPRILADIE
Mvan_0625|M.vanbaalenii_PYR-1 SGLPALREVIDQQFAQRSDLLKAHTALLSLRQFVQRHPIYATPRILADIE
MSMEG_0698|M.smegmatis_MC2_155 SGLIALRDVIDQQFAQRSELLKAHTALLSLRQFVQHNPIYATPYILADIE
TH_1301|M.thermoresistible__bu SGLIALRDVIDQQFAQRSDLLKAHTALLSLRQFVQRHPIYATPYILADIE
MAB_4282c|M.abscessus_ATCC_199 SGLVELHNIIANQFGQRAGILKSHTALLSARRVLTTYPVHGGRRVIDDID
*** *:::* :**.**: :**:*:**:* *:.: *: . :: **:
Mb0350|M.bovis_AF2122/97 PLLADTHAFEELRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGL
Rv0343|M.tuberculosis_H37Rv PLLADTHAFEELRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGL
MMAR_0616|M.marinum_M PLLADTHAFEELRVLSLLPSQATTLNDEELVSLRRIIGGSGTSPAARLGL
MUL_0581|M.ulcerans_Agy99 PLLADTHAFEELRVLSLLPSQATTLNDEELVSLRRIIGGSGTSPAARLGL
Mflv_0272|M.gilvum_PYR-GCK PLLADTHAFEELRLLSRLRSRPTTLNDDEMASLRRVIGGSGTDVASRLGL
Mvan_0625|M.vanbaalenii_PYR-1 PLLADTHAFEELRLLSQLRSRATTLNDDEMASLRRLIGGSGTDAASRLGL
MSMEG_0698|M.smegmatis_MC2_155 PLLADTHAFEELRLLSQLRSRPTTLNEDEMASLRRIIGGSGTDAASRLGL
TH_1301|M.thermoresistible__bu PLLADTHAFEELRLLSQLRSRPTTLNEEEMASLRRLLGGSGTDAASRLGL
MAB_4282c|M.abscessus_ATCC_199 PLLADTHAFDELRLLAELSSRSTTLTEHETMLIRRLLGSFGTDAAARLGL
*********:***:*: * *:.***.:.* :**::*. **. *:****
Mb0350|M.bovis_AF2122/97 DPANSREAPRAALAAAQHWRRRAAHPLNDPFTTRACRAAVRSAEAMVAEF
Rv0343|M.tuberculosis_H37Rv DPANSREAPRAALAAAQHWRRRAAHPLNDPFTTRACRAAVRSAEAMVAEF
MMAR_0616|M.marinum_M DPQHRHDGPRAAFAAAQRWRRRADHPLNDPFTTRACRAAVRSAEAMVAEF
MUL_0581|M.ulcerans_Agy99 DPQHRHDGPRAAFAAAQRWRRRADHPLNDPFTTRACRAAVRSAEAMVAEF
Mflv_0272|M.gilvum_PYR-GCK PPGDESDGPRAAFAAVQRWRRRADHPLNDPFTARACRAAVRSAEAIVADY
Mvan_0625|M.vanbaalenii_PYR-1 SPDTVGDGPRAAFAAAQRWRRRAEHPLNDPFTARACRAAVRSAEALVAEY
MSMEG_0698|M.smegmatis_MC2_155 TPDAPYDGPRAAFAAAQRWRRRAEHPLNDPFTTRACRAAVRSAEALVAEY
TH_1301|M.thermoresistible__bu SPDAPYDGPRAAFAAAQRWRRRAEHPLNDPFTTRACRAAVRSAEALVAEY
MAB_4282c|M.abscessus_ATCC_199 D-ETRSDPRRAALDAVGRWRARAEHPLNDPFTSRLCLAAVRSAEGILTQL
: ***: *. :** ** ********:* * *******.::::
Mb0350|M.bovis_AF2122/97 SARR----
Rv0343|M.tuberculosis_H37Rv SARR----
MMAR_0616|M.marinum_M AARR----
MUL_0581|M.ulcerans_Agy99 AARR----
Mflv_0272|M.gilvum_PYR-GCK ARRGR---
Mvan_0625|M.vanbaalenii_PYR-1 ARA-----
MSMEG_0698|M.smegmatis_MC2_155 AARQR---
TH_1301|M.thermoresistible__bu AALGRR--
MAB_4282c|M.abscessus_ATCC_199 SAHDRPAY
: