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M. marinum M MMAR_0616 (iniC)

annotation: isoniazid inductible protein IniC
coordinates: 727680 - 729161
length: 493

VSTSDRVRAILGGTIQAYRGEPAYRQRADVFYELDRIGARLSEPIRIALAGTLKAGKSTLVNALVGDDIA
PTDATEATRIVTGFRHGPTPRVTANHRGGRRVNVPITHRDGLSFDLRRLNPAEIADLDVEWPAEELVNTT
IIDTPGTSSLNRDTSERTLRLLVPADGVPRVDAVVFLLRTLNAADIALLKQIGGLVGDSAGALGIIGVAS
RADEIGAGRIDAMSSAQDVAKRFTAELSQTGICQAVVPVSGLLALTARTLRQSEFAALKKLAGADSTELN
KALLSVDRFVRPDSPLPVDAGTRAQLLERFGMFGIRISIAGLAAGIADSAGLAAELLERSGLVALREVID
QQFAQRSDMLKAHTALVSLRRFVQAHPVMATPYVIADIDPLLADTHAFEELRVLSLLPSQATTLNDEELV
SLRRIIGGSGTSPAARLGLDPQHRHDGPRAAFAAAQRWRRRADHPLNDPFTTRACRAAVRSAEAMVAEFA
ARR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0616iniC-100% (493)isoniazid inductible protein IniC
M. marinum MMMAR_0615iniA2e-1127.71% (249) hypothetical protein MMAR_0615

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0350iniC0.087.22% (493) isoniazid inductible gene protein INIC
M. gilvum PYR-GCKMflv_0272-0.079.18% (466) isoniazid inductible gene protein IniC
M. tuberculosis H37RvRv0343iniC0.087.22% (493) isoniazid inductible gene protein INIC
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4282c-1e-16763.21% (492) isoniazid inductible gene protein IniC
M. avium 104-----
M. smegmatis MC2 155MSMEG_0698-0.078.83% (496) isoniazid inductible protein IniC
M. thermoresistible (build 8)TH_1301-0.080.41% (485) ISONIAZID INDUCTIBLE GENE PROTEIN INIC
M. ulcerans Agy99MUL_0581iniC0.099.59% (493) protein IniC
M. vanbaalenii PYR-1Mvan_0625-0.077.73% (494) isoniazid inductible gene protein IniC

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0616|M.marinum_M               MSTSDRVRAILGGTIQAYRGEPAYRQRADVFYELDRIGARLSEPIRIALA
MUL_0581|M.ulcerans_Agy99           MSTSDRVRAILGGTIQAYRGEPAYRQRADVFYELDRIGARLSEPIRIALA
Mb0350|M.bovis_AF2122/97            MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALA
Rv0343|M.tuberculosis_H37Rv         MSTSDRVRAILHATIQAYRGAPAYRQRGDVFCQLDRIGARLAEPLRIALA
Mflv_0272|M.gilvum_PYR-GCK          -----------------------------MHAELDRIGRRLNEPMRIALA
Mvan_0625|M.vanbaalenii_PYR-1       ------MRAILGGTIAAYRADPAYRQRPDLHAELERIGRRLNEPMRIALA
MSMEG_0698|M.smegmatis_MC2_155      MSTGDQVRAILRGTVQAYRGDPAYRHRPDVHNELERIGWQLNQPIRIALA
TH_1301|M.thermoresistible__bu      ------VRAILGGTIRAYRAEAAYRDRPDVHNELMRIGARLNEPIRVALA
MAB_4282c|M.abscessus_ATCC_199      MSSVVQARVIISDAMRAYQNDSRYLRVAEPHDELRRIAARLDEPIRVAIA
                                                                  . :* **. :* :*:*:*:*

MMAR_0616|M.marinum_M               GTLKAGKSTLVNALVGDDIAPTDATEATRIVTGFRHGPTPRVTANHRGGR
MUL_0581|M.ulcerans_Agy99           GTLKAGKSTLVNALVGDDIAPTDATEATRIVTGFRHGPTPRVTANHRGGC
Mb0350|M.bovis_AF2122/97            GTLKAGKSTLVNALVGDDIAPTDATEATRIVTWFRHGPTPRVTANHRGGR
Rv0343|M.tuberculosis_H37Rv         GTLKAGKSTLVNALVGDDIAPTDATEATRIVTWFRHGPTPRVTANHRGGR
Mflv_0272|M.gilvum_PYR-GCK          GTLKAGKSTLVNALVGETIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
Mvan_0625|M.vanbaalenii_PYR-1       GTLKAGKSTLVNALVGDEIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
MSMEG_0698|M.smegmatis_MC2_155      GTLKAGKSTLVNALLGEEIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
TH_1301|M.thermoresistible__bu      GTLKAGKSTLVNALVGESIAPTDATEATRIVTWFRHGPTPKVTANHRGGR
MAB_4282c|M.abscessus_ATCC_199      GTLNAGKSTLVNALVGEDIAPTDATEATRIVAWFRHGAAPRVTANLFSGV
                                    ***:**********:*: *************: ****.:*:****  .* 

MMAR_0616|M.marinum_M               RVNVPITHRD-------GLSFDLRRLNPAEIADLDVEWPAEELVNTTIID
MUL_0581|M.ulcerans_Agy99           RVNVPITHRD-------GLSFDLRRLNPAEIADLDVEWPAEELVNTTIID
Mb0350|M.bovis_AF2122/97            RANVPITRRG-------GLSFDLRRINPAELIDLEVEWPAEELIDATIVD
Rv0343|M.tuberculosis_H37Rv         RANVPITRRG-------GLSFDLRRINPAELIDLEVEWPAEELIDATIVD
Mflv_0272|M.gilvum_PYR-GCK          RTNVPIARD---PHAG-GLTFDFARLDPDDVLDLDVEWPASELVDATIID
Mvan_0625|M.vanbaalenii_PYR-1       RSNVPITRDRADPQGRRGLTFDFASLDPDDVVDLDVEWPAAELIDATIID
MSMEG_0698|M.smegmatis_MC2_155      RSNVPIVRDP----HDRGLTFRFDGLDPGEILDLDVEWPAVELIDTTIID
TH_1301|M.thermoresistible__bu      RSNVPITRN-------GGLTFDFANLDPEDIVDLEVEWPAAELIDYTIID
MAB_4282c|M.abscessus_ATCC_199      RQDIPIRREG-------GLSFELDRLDPASVADLDVNWPAPELNEITLID
                                    * ::** :         **:* :  ::* .: **:*:*** ** : *::*

MMAR_0616|M.marinum_M               TPGTSSLNRDTSERTLRLLVPADGVPRVDAVVFLLRTLNAADIALLKQIG
MUL_0581|M.ulcerans_Agy99           TPGTSSLNRDTSERTLRLLVPADGVPRVDAVVFLLRTLNAADIALLKQIG
Mb0350|M.bovis_AF2122/97            TPGTSSLACDASERTLRLLVPADGVPRVDAVVFLLRTLNAADVALLKQIG
Rv0343|M.tuberculosis_H37Rv         TPGTSSLACDASERTLRLLVPADGVPRVDAVVFLLRTLNAADVALLKQIG
Mflv_0272|M.gilvum_PYR-GCK          TPGTSSLSKDVSARTLRLLVPDDGVPRVDAVVFLLRTLNAPDIALLKQIG
Mvan_0625|M.vanbaalenii_PYR-1       TPGTSSLSQDVSARTLRLLVPDDGVPRVDAVVFLLRTLNAADIALLKQIG
MSMEG_0698|M.smegmatis_MC2_155      TPGTSSLSQDVSERTYRLLVPDDGVPRVDAVVFLLRTLNAADIALLKQIG
TH_1301|M.thermoresistible__bu      TPGTSSLNRDVSERTLRLLVPEDGVPRVDAVVFLLRTLNAADIALLKQIG
MAB_4282c|M.abscessus_ATCC_199      TPGTSSLSTDVSERSLALLVPEDGVPRVDAVIFLLRSLNAADIGLLTQIG
                                    *******  *.* *:  **** *********:****:***.*:.**.***

MMAR_0616|M.marinum_M               GLVGDS-AGALGIIGVASRADEIGAGRIDAMSSAQDVAKRFTAELSQTGI
MUL_0581|M.ulcerans_Agy99           GLVGDS-AGALGIIGVASRADEIGAGRIDAMSSAQDVAKRFTAELSQTGI
Mb0350|M.bovis_AF2122/97            GLVGGS-VGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQMGI
Rv0343|M.tuberculosis_H37Rv         GLVGGS-VGALGIIGVASRADEIGAGRIDAMLSANDVAKRFTRELNQMGI
Mflv_0272|M.gilvum_PYR-GCK          ELVGGS-SGALGVIGVASRADEIGAGRIDAMMSAGDVAARFTKEMEQTGI
Mvan_0625|M.vanbaalenii_PYR-1       ELVGGA-AGALGVIGVASRADEIGAGRIDAMMSARDVAQRFTAEMERTGI
MSMEG_0698|M.smegmatis_MC2_155      ELVGGS-SGALGVIGVASRADEIGAGRIDAMMSAKDVAKRFTAEMDKTGI
TH_1301|M.thermoresistible__bu      DLVGGS-AGALGVIGVASRADEIGAGRIDAMLSAKDVAKRFTDELERTGV
MAB_4282c|M.abscessus_ATCC_199      KLVGGERGGAVGVVGVVSRADEIGVGRLDAMLSAREVAARFAGEMERTGI
                                     ***.   **:*::**.*******.**:*** ** :** **: *:.: *:

MMAR_0616|M.marinum_M               CQAVVPVSGLLALTARTLRQSEFAALKKLAGADSTELNKALLSVDRFVRP
MUL_0581|M.ulcerans_Agy99           CQAVVPVSGLLALTARTLRQSEFAALKKLAGADSTELNKALLSVDRFVRP
Mb0350|M.bovis_AF2122/97            CQAVVPVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRR
Rv0343|M.tuberculosis_H37Rv         CQAVVPVSGLLALTARTLRQTEFIALRKLAGAERTELNRALLSVDRFVRR
Mflv_0272|M.gilvum_PYR-GCK          CQAVVPVSGLLALTARTLRQSEFGALDKLAGVEPAELAKAMLSVDRFVRE
Mvan_0625|M.vanbaalenii_PYR-1       CQAVVPVSGLLALTARTLRQSEFVALKKLSEVEPAQLAKAMLSVDRFVRA
MSMEG_0698|M.smegmatis_MC2_155      CQAVVPVSGLLAVTARTLRQSEFVALEKLAGVDPAELAKAMLSVDRFVRE
TH_1301|M.thermoresistible__bu      CQAVVPVSGLLALTARTLRQSEFVALERLAGVDPAVLTKAMLSVDRFVRE
MAB_4282c|M.abscessus_ATCC_199      CQAVVPVAGLLALTARTLRQAEFVALQRLAELDPQVLAKALLSVDRFVRE
                                    *******:****:*******:** ** :*:  :   * :*:******** 

MMAR_0616|M.marinum_M               DS---PLPVDAGTRAQLLERFGMFGIRISIAGLAAGIADSAGLAAELLER
MUL_0581|M.ulcerans_Agy99           DS---PLPVDAGTRAQLLERFGMFGIRISIAGLAAGIADSAGLAAELLER
Mb0350|M.bovis_AF2122/97            DS---PLPVDAGIRAQLLERFGMFGIRMSIAVLAAGVTDSTGLAAELLER
Rv0343|M.tuberculosis_H37Rv         DS---PLPVDAGIRAQLLERFGMFGIRMSIAVLAAGVTDSTGLAAELLER
Mflv_0272|M.gilvum_PYR-GCK          DS---PLPVDAATRAALLDRFGMFGLRISIAVLRAGVRDSVALAEELLER
Mvan_0625|M.vanbaalenii_PYR-1       DSEDTALPVSSGTRAELLDRFGMFGIRIAIAVLRAGVGDSVALADELLER
MSMEG_0698|M.smegmatis_MC2_155      DS---ALPVDAATRAALLDRFGMFGIRISIAVLRAGVSDSVALADELLER
TH_1301|M.thermoresistible__bu      DA---DLPVDAATRAALLDRFGMFGIRISIAVLRAGIKDSVALADELLER
MAB_4282c|M.abscessus_ATCC_199      DD---SLPVDAQTRAALLHRFGMFGIRISVAVMRVGVTDATGLAEELLER
                                    *     ***.:  ** **.******:*:::* : .*: *:..** *****

MMAR_0616|M.marinum_M               SGLVALREVIDQQFAQRSDMLKAHTALVSLRRFVQAHPVMATPYVIADID
MUL_0581|M.ulcerans_Agy99           SGLVALREVIDQQFAQRSDMLKAHAALVSLRRFVQAHPVMATPYVIADID
Mb0350|M.bovis_AF2122/97            SGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADID
Rv0343|M.tuberculosis_H37Rv         SGLVALRNVIDQQFAQRSDMLKAHTALVSLRRFVQTHPVPATPYVIADID
Mflv_0272|M.gilvum_PYR-GCK          SGLVALRDVIDQQFAQRSDLLKAHTALLSLRQFVQRNPVYATPRILADIE
Mvan_0625|M.vanbaalenii_PYR-1       SGLPALREVIDQQFAQRSDLLKAHTALLSLRQFVQRHPIYATPRILADIE
MSMEG_0698|M.smegmatis_MC2_155      SGLIALRDVIDQQFAQRSELLKAHTALLSLRQFVQHNPIYATPYILADIE
TH_1301|M.thermoresistible__bu      SGLIALRDVIDQQFAQRSDLLKAHTALLSLRQFVQRHPIYATPYILADIE
MAB_4282c|M.abscessus_ATCC_199      SGLVELHNIIANQFGQRAGILKSHTALLSARRVLTTYPVHGGRRVIDDID
                                    ***  *:::* :**.**: :**:*:**:* *:.:   *: .   :: **:

MMAR_0616|M.marinum_M               PLLADTHAFEELRVLSLLPSQATTLNDEELVSLRRIIGGSGTSPAARLGL
MUL_0581|M.ulcerans_Agy99           PLLADTHAFEELRVLSLLPSQATTLNDEELVSLRRIIGGSGTSPAARLGL
Mb0350|M.bovis_AF2122/97            PLLADTHAFEELRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGL
Rv0343|M.tuberculosis_H37Rv         PLLADTHAFEELRMLSLLPSRATTLNDDEIASLRRIIGGSGTSAAARLGL
Mflv_0272|M.gilvum_PYR-GCK          PLLADTHAFEELRLLSRLRSRPTTLNDDEMASLRRVIGGSGTDVASRLGL
Mvan_0625|M.vanbaalenii_PYR-1       PLLADTHAFEELRLLSQLRSRATTLNDDEMASLRRLIGGSGTDAASRLGL
MSMEG_0698|M.smegmatis_MC2_155      PLLADTHAFEELRLLSQLRSRPTTLNEDEMASLRRIIGGSGTDAASRLGL
TH_1301|M.thermoresistible__bu      PLLADTHAFEELRLLSQLRSRPTTLNEEEMASLRRLLGGSGTDAASRLGL
MAB_4282c|M.abscessus_ATCC_199      PLLADTHAFDELRLLAELSSRSTTLTEHETMLIRRLLGSFGTDAAARLGL
                                    *********:***:*: * *:.***.:.*   :**::*. **. *:****

MMAR_0616|M.marinum_M               DPQHRHDGPRAAFAAAQRWRRRADHPLNDPFTTRACRAAVRSAEAMVAEF
MUL_0581|M.ulcerans_Agy99           DPQHRHDGPRAAFAAAQRWRRRADHPLNDPFTTRACRAAVRSAEAMVAEF
Mb0350|M.bovis_AF2122/97            DPANSREAPRAALAAAQHWRRRAAHPLNDPFTTRACRAAVRSAEAMVAEF
Rv0343|M.tuberculosis_H37Rv         DPANSREAPRAALAAAQHWRRRAAHPLNDPFTTRACRAAVRSAEAMVAEF
Mflv_0272|M.gilvum_PYR-GCK          PPGDESDGPRAAFAAVQRWRRRADHPLNDPFTARACRAAVRSAEAIVADY
Mvan_0625|M.vanbaalenii_PYR-1       SPDTVGDGPRAAFAAAQRWRRRAEHPLNDPFTARACRAAVRSAEALVAEY
MSMEG_0698|M.smegmatis_MC2_155      TPDAPYDGPRAAFAAAQRWRRRAEHPLNDPFTTRACRAAVRSAEALVAEY
TH_1301|M.thermoresistible__bu      SPDAPYDGPRAAFAAAQRWRRRAEHPLNDPFTTRACRAAVRSAEALVAEY
MAB_4282c|M.abscessus_ATCC_199      D-ETRSDPRRAALDAVGRWRARAEHPLNDPFTSRLCLAAVRSAEGILTQL
                                          :  ***: *. :** ** ********:* * *******.:::: 

MMAR_0616|M.marinum_M               AARR----
MUL_0581|M.ulcerans_Agy99           AARR----
Mb0350|M.bovis_AF2122/97            SARR----
Rv0343|M.tuberculosis_H37Rv         SARR----
Mflv_0272|M.gilvum_PYR-GCK          ARRGR---
Mvan_0625|M.vanbaalenii_PYR-1       ARA-----
MSMEG_0698|M.smegmatis_MC2_155      AARQR---
TH_1301|M.thermoresistible__bu      AALGRR--
MAB_4282c|M.abscessus_ATCC_199      SAHDRPAY
                                    :